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Showing 1–24 of 728 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Intervention: Sedation Clear all
Completed Phase 4 Interventional Results available

Alternative Sedation During Bronchoscopy

NCT01158820
View directory record Official record
Conditions
Sedation
Interventions
Dexmedetomidine load, Ketamine load, Midazolam load, Fentanyl load, Dexmedetomidine maintenance, Ketamine maintenance, Midazolam demand, Fentanyl demand, Benadryl demand
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 25, 2019 · Synced Sep 2, 2026, 2:15 AM EDT
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

Proposal To Develop A Rapid And Cost-Effective Diagnostic Test For Schizophrenia

NCT03781115
View directory record Official record
Conditions
Schizophrenia
Interventions
Ziprasidone, Olanzapine, Placebo Comparator
Drug
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 40 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2027
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Sep 2, 2026, 2:15 AM EDT
Completed Not applicable Interventional

Post Anesthesia Care Unit (PACU) Weighted Blanket Study

NCT05632640
View directory record Official record
Conditions
Cardiac Catheterization, Electrophysiology Procedure, Pediatric Cardiology
Interventions
Standard of Care, Weighted blanket
Other · Device
Lead sponsor
University of Michigan
Other
Eligibility
3 Years to 17 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 24, 2025 · Synced Sep 2, 2026, 2:15 AM EDT
Withdrawn Phase 2Phase 3 Interventional

Dexmedetomidine Effects on Microelectrode Recording in Deep Brain Stimulation

NCT00608231
View directory record Official record
Conditions
Parkinson's Disease, Essential Tremor, Dystonia
Interventions
Dexmedetomidine Hydrochloride Infusion, Normal Saline
Drug
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 30, 2014 · Synced Sep 2, 2026, 2:15 AM EDT
Completed Not applicable Interventional

MIVetsCan: Can-Coach Trial (Phase 1)

NCT06320470
View directory record Official record
Conditions
Chronic Pain
Interventions
Educational Session
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Sep 2, 2026, 2:15 AM EDT
Completed Not applicable Interventional

The Utility of Pretracheal Stethoscope in Detecting Respiratory Abnormalities in Sedated Children

NCT01957566
View directory record Official record
Conditions
Sedation
Interventions
APS
Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
2 Years to 18 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 25, 2018 · Synced Sep 2, 2026, 2:15 AM EDT
Withdrawn Phase 4 Interventional

Safety and Efficacy of Intravenous (IV) Dexmedetomidine During Flexible Bronchoscopy and Endobronchial Ultrasound

NCT00691886
View directory record Official record
Conditions
Pain
Interventions
dexmedetomidine hydrochloride
Drug
Lead sponsor
Lahey Clinic
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Burlington, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 9, 2012 · Synced Sep 2, 2026, 2:15 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Reduction of Conscious Sedation Requirements by Olfactory Stimulation

NCT00417001
View directory record Official record
Conditions
Colon Cancer Screening, Colon Polyps
Interventions
Aroma therapy
Procedure
Lead sponsor
United States Naval Medical Center, Portsmouth
Federal
Eligibility
21 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Portsmouth, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 16, 2025 · Synced Sep 2, 2026, 2:15 AM EDT
Completed Not applicable Interventional Results available

Laparotomy vs. Drainage for Infants With Necrotizing Enterocolitis

NCT01029353
View directory record Official record
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Enterocolitis, Necrotizing, Intestinal Perforation
Interventions
Laparotomy, Drainage
Procedure
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 8 Weeks
Enrollment
529 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2019
U.S. locations
22
States / cities
Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 18 more
Source: ClinicalTrials.gov public record
Updated Jul 17, 2024 · Synced Sep 2, 2026, 2:15 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Sedation Regimens in GI Endoscopy

NCT04807101
View directory record Official record
Conditions
Anesthesia, Endoscopy, Colonoscopy, Conscious Sedation
Interventions
midazolam alone
Drug
Lead sponsor
Greg S Cohen MD LLC
Other
Eligibility
18 Years to 75 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 14, 2024 · Synced Sep 2, 2026, 2:15 AM EDT
Completed Phase 3 Interventional Results available

Ketamine Versus Co-administration of Ketamine and Propofol for Procedural Sedation in a Pediatric Emergency Department

NCT01387139
View directory record Official record
Conditions
Procedural Sedation and Analgesia
Interventions
Ketamine, Ketamine Co-administered with Propofol
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
3 Years to 21 Years
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 7, 2017 · Synced Sep 2, 2026, 2:15 AM EDT
Recruiting Not applicable Interventional

Platform of Randomized Adaptive Clinical Trials in Critical Illness

NCT05440851
View directory record Official record
Conditions
Respiratory Insufficiency, Extracorporeal Membrane Oxygenation Complication, Mechanical Ventilation Pressure High
Interventions
Ultra-Protective Ventilation Facilitated by Extracorporeal Support, Lung-Protective Ventilation (LPV), Driving Pressure-Limited Ventilation (DPL), Lung- and Diaphragm-Protective Ventilation and Sedation (LDPVS), Early Cohort corticosteroid dose, Extended Cohort corticosteroid dose, Usual care without routine corticosteroids, Usual care without extending corticosteroids, Usual care with fludrocortisone, Usual care without fludrocortisone, Drug 4 mL:, Drug 40 mg:, PEEP-20, PEEP-AOP, PEEP-10, VV ECMO-facilitated strategy of earlier awakening, extubation and rehabilitation, Electrical impedance tomography (EIT), no treatment / intervention arm is involved., Usual care, Early Routine IMT
Other · Drug
Lead sponsor
University Health Network, Toronto
Other
Eligibility
18 Years and older
Enrollment
6,250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
26
States / cities
Tucson, Arizona • Los Angeles, California • San Diego, California + 19 more
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Sep 2, 2026, 2:15 AM EDT
Completed Not applicable Interventional

Water-aided Colonoscopy vs Air Insufflation Colonoscopy in Colorectal Cancer Screening

NCT02041507
View directory record Official record
Conditions
Colorectal Cancer, Colorectal Adenomas, Colorectal Polyps, Pain
Interventions
Air insufflation method., Water Immersion method., Water Exchange method.
Other
Lead sponsor
Presidio Ospedaliero Santa Barbara
Other
Eligibility
50 Years to 70 Years
Enrollment
1,224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 12, 2016 · Synced Sep 2, 2026, 2:15 AM EDT
Completed No phase listed Observational

The Effect of Midazolam Sedation on Diagnostic Medial Branch Blocks

NCT04453449
View directory record Official record
Conditions
Lumbar Spine Spondylosis, Anxiety Generalized
Interventions
Midazolam
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 6, 2022 · Synced Sep 2, 2026, 2:15 AM EDT
Active, not recruiting Not applicable Interventional

PICU Up!: A Pilot Stepped-wedge Trial of a Multicomponent Early Mobility Intervention for Critically Ill Children

NCT03860168
View directory record Official record
Conditions
Critical Illness
Interventions
PICU Up!
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
0 Years to 24 Years
Enrollment
2,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Sep 2, 2026, 2:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Opioid Use in Shoulder Arthroplasty Patients: A Stratification and Algorithm

NCT03808025
View directory record Official record
Conditions
Opioid Use
Interventions
opioid education
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Aug 31, 2023 · Synced Sep 2, 2026, 2:15 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

SGA for TEE: Safe Alternative to Deep Sedation for Patients With High-risk Cardiopulmonary Disease.

NCT04939220
View directory record Official record
Conditions
Cardiopulmonary Disease
Interventions
TEE with SGA, TEE with Deep Sedation
Procedure
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 120 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 20, 2024 · Synced Sep 2, 2026, 2:15 AM EDT
Completed No phase listed Observational

Investigate the Aerosol Particle Distribution During Aerosol Generating Procedures

NCT04353531
View directory record Official record
Conditions
Transmission, Patient Professional, High-flow Nasal Cannula
Interventions
High-flow nasal cannula, Surgical mask, bronchoscopy examination, intubation, tracheostomy, nebulization, Pulmonary function test
Device · Procedure · Diagnostic Test
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 22, 2021 · Synced Sep 2, 2026, 2:15 AM EDT
Completed Not applicable Interventional Results available

Using Capnography to Reduce Hypoxia During Pediatric Sedation

NCT01463527
View directory record Official record
Conditions
Hypoventilation, Hypoxia
Interventions
Nellcor NPB-70 Capnograph
Device
Lead sponsor
Yale University
Other
Eligibility
1 Year to 20 Years
Enrollment
167 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 10, 2018 · Synced Sep 2, 2026, 2:15 AM EDT
Completed No phase listed Observational

Prospective Study Assessing the Validity of Y-PAS (Yale Preoperative Anxiety Scale) to Predict Patients Undergoing Magnetic Resonance Imaging Without the Use of Sedation/General Anesthesia

NCT02586103
View directory record Official record
Conditions
Magnetic Resonance Imaging
Interventions
MRI simulation
Device
Lead sponsor
Arlyne Thung
Other
Eligibility
Not listed
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 19, 2017 · Synced Sep 2, 2026, 2:15 AM EDT
Enrolling by invitation No phase listed Observational

MRI and Computational Simulation Cardiology Study

NCT03149341
View directory record Official record
Conditions
Congenital Heart Disease, Pulmonary Hypertension
Interventions
Magnetic Resonance Imaging
Other
Lead sponsor
Stanford University
Other
Eligibility
Not listed
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2029
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Dec 17, 2024 · Synced Sep 2, 2026, 2:15 AM EDT
Completed Not applicable Interventional

Music Therapy With Intubated and Sedated Pediatric Patients

NCT03629145
View directory record Official record
Conditions
Respiratory Syncytial Virus Infections
Interventions
Live Music Therapy, Recorded Music Therapy
Behavioral
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
Up to 2 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 25, 2019 · Synced Sep 2, 2026, 2:15 AM EDT
Not listed Phase 4 Interventional

Nitrous Oxide Prior to Intranasal Midazolam for Moderate Dental Sedation in Pediatric Patients

NCT04083105
View directory record Official record
Conditions
Dental Anxiety, Pain
Interventions
Nitrous Oxide, Midazolam
Drug
Lead sponsor
Children's Hospital Colorado
Other
Eligibility
3 Years to 8 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 9, 2019 · Synced Sep 2, 2026, 2:15 AM EDT
Completed Not applicable Interventional Results available

Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Control During First Trimester Abortion

NCT03187002
View directory record Official record
Conditions
Abortion in First Trimester
Interventions
Transcutaneous electrical nerve stimulation (TENS), Moderate IV Sedation, SHAM: Transcutaneous electrical nerve stimulation (TENS), SHAM: Moderate IV Sedation
Device · Drug · Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
San Jose, California
Source: ClinicalTrials.gov public record
Updated Nov 1, 2020 · Synced Sep 2, 2026, 2:15 AM EDT