Independent directory Public ClinicalTrials.gov records United States
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Showing 121–144 of 729 matching trials from the live ClinicalTrials.gov search.
Not yet recruiting Phase 4 Interventional

The Use of Remimazolam for TEE

NCT07829458
Conditions
Cardiac Disease, Anesthesia
Interventions
Remimazolam, Propofol
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

A Pilot Study of Local Anesthesia for Inguinal Hernia Surgery in Older Adults

NCT04706026
Conditions
Inguinal Hernia, Anesthesia, Local
Interventions
Open Inguinal Hernia Repair - Local Anesthesia, Inguinal Hernia Repair - General Anesthesia
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
60 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
3
States / cities
Dallas, Texas • Houston, Texas • Madison, Wisconsin
Conditions
Sedation, Anxiety, Pain
Interventions
Sublingual Sufentanil/Triazolam NanoTab™ (ARX-F03), Placebo NanoTab™
Drug
Lead sponsor
Talphera, Inc
Industry
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Pasadena, California
Completed No phase listed Observational Accepts healthy volunteers

Hemodynamic Changes During Implant Surgery with Intravenous Conscious Sedation

NCT05756439
Conditions
Blood Pressure, Dental Anxiety
Interventions
Intravenous Sedatives with or Without Analgesia, No IV sedation
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Completed Not applicable Interventional Results available

Acupuncture for Low-Dose Opioid for TKA Replacement

NCT04084288
Conditions
Knee Osteoarthritis, Pain, Postoperative, Acupuncture
Interventions
Acupuncture, Peripheral Nerve Stimulator
Other · Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 70 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
New York, New York
Suspended Phase 2 Interventional Accepts healthy volunteers

A Study of Human Multi-Sensory Integration

NCT03498391
Conditions
Anesthesia Awareness
Interventions
Propofol, Ketamine Injectable Product
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Osteoarthritis
Interventions
Bupivacaine, Morphine, Methylprednisolone, Cefazolin, Normal saline, Midazolam, Propofol, Dexamethasone, 8 MHz. Chiba needle, 22 G / 4 inches
Drug · Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
New York, New York
Conditions
Claustrophobia, Complication of Diagnostic Procedure
Interventions
Comfort Talk®
Behavioral
Lead sponsor
Hypnalgesics, LLC
Industry
Eligibility
Not listed
Enrollment
97,712 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
4
States / cities
Boston, Massachusetts • Brookline, Massachusetts • Columbus, Ohio
Conditions
Contraceptive Devices, Long-Acting Reversible Contraception, Analgesia, Adolescent Health, Gynecology
Interventions
Nitrous oxide gas for inhalation, Oxygen Gas for Inhalation
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
14 Years to 24 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Pain
Interventions
normal saline, lidocaine
Drug
Lead sponsor
Akron Children's Hospital
Other
Eligibility
2 Years to 7 Years
Enrollment
109 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Akron, Ohio
Terminated Phase 4 Interventional Results available

Multimodal Analgesia in Cardiac Surgery (Pilot Study)

NCT02734940
Conditions
Heart Diseases
Interventions
Lidocaine, Unrestricted Fentanyl, Ketamine, Precedex, Duramorph
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Richmond, Virginia
Conditions
Acute Respiratory Failure, Encephalopathy, ARDS, Sepsis, Critical Illness
Interventions
Exersides
Device
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
3
States / cities
San Diego, California • Baltimore, Maryland • Burlington, Vermont
Terminated Phase 1Phase 2 Interventional Results available

RCT for Women With a Persisting Pregnancy of Unknown Location

NCT01800162
Conditions
Persistent Pregnancy of Unknown Location, Ectopic Pregnancy
Interventions
Methotrexate, Uterine Evacuation, Expectant Management
Drug · Procedure · Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older · Female only
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Greenville, South Carolina
Conditions
Pain, Postoperative
Interventions
Fentanyl
Drug
Lead sponsor
Bassett Healthcare
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2014
U.S. locations
1
States / cities
Cooperstown, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluating the Feasibility of VR for Pediatric Renal Biopsies

NCT05267704
Conditions
Pain, Procedural, Procedural Anxiety, Sedation Complication
Interventions
Oculus Go Virtual Reality Headset
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
5 Years to 17 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Francisco, California
Conditions
Osteoid Osteoma
Interventions
MR-HIFU
Device
Lead sponsor
Children's National Research Institute
Other
Eligibility
Up to 25 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Colonoscopy
Interventions
Remimazolam, Midazolam, Placebo
Drug
Lead sponsor
Paion UK Ltd.
Industry
Eligibility
18 Years and older
Enrollment
461 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
13
States / cities
Mobile, Alabama • Anaheim, California • Chula Vista, California + 10 more
Conditions
HIV-1-infection, HIV Disease Progression, Inflammation, HIV
Interventions
Venipuncture, Targeted physical medical exam, Urine pregnancy test, Anoscopy, Esophagogastroduodenoscopy (EGD)
Procedure
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Terminated Phase 2Phase 3 Interventional Results available

Clonidine to Treat Iatrogenic-induced Opioid Dependence in Infants

NCT01360450
Conditions
Neonatal Abstinence Syndrome
Interventions
Clonidine HCL, saline
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
5 Days to 90 Days
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Baltimore, Maryland
Withdrawn Not applicable Interventional Accepts healthy volunteers

Use of EndoFLIP and Manometry Prior to G-POEM

NCT04844190
Conditions
Gastroparesis
Interventions
EndoFLIP, Antroduodenal Manometry
Diagnostic Test
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Anesthesia
Interventions
Accelerometer
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 90 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Airway Obstruction, Apnea, Hypopnea
Interventions
Airway Management System (AMS)
Device
Lead sponsor
5i Sciences, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
La Jolla, California
Conditions
Colon Adenocarcinoma
Interventions
Biospecimen Collection, Electronic Health Record Review, Fentanyl Citrate, Propofol, Questionnaire Administration, Sevoflurane, Surgical Procedure
Procedure · Other · Drug
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Kansas City, Kansas
Conditions
Acute Pain
Interventions
Twin block local anesthetic nerve block using standard dental anesthetic, Twin block with placebo
Drug · Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Newark, New Jersey