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ClinicalTrials.gov public records Last synced Nov 5, 2026, 1:22 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 913–936 of 1,580 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Self help Clear all

Conditions: Depression
Interventions: Enhanced Usual Care (EUC), Supported Online Self-help for Depression (SOS-Depression); Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 2
States / cities: San Diego, California • West Los Angeles, California

Conditions: Insomnia Disorder
Interventions: Virtual Coaching; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 100 Years
Enrollment: 244 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 5
States / cities: West Haven, Connecticut • Augusta, Maine • Leeds, Massachusetts + 2 more

Conditions: Sexual Behavior
Interventions: Media Aware Sexual Health - High School; Other
Lead sponsor: Innovation Research & Training; Other
Eligibility: 12 Years to 17 Years
Enrollment: 590 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Dementia, Mild, Mild Cognitive Impairment (MCI)
Interventions: Let's Talk Tech; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 222 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Type II Diabetes, Primary Health Care, Behavioral Health
Interventions: INTEGRATE-D; Behavioral
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 18 Years and older
Enrollment: 294 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Executive Dysfunction, Cognitive Impairment
Interventions: ASCEND-I; Behavioral
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 30 Years to 89 Years
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: New York, New York

Conditions: Post-discharge
Interventions: Telemonitoring plus self-management support; Other
Lead sponsor: University of Michigan; Other
Eligibility: 21 Years and older
Enrollment: 246 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Epilepsy, Cognitive Dysfunction, Cognitive Disorder, Memory and Thinking Problems
Interventions: HOBSCOTCH/HOBSCOTCH-YOUTH; Other
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 13 Years to 29 Years
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Lebanon, New Hampshire

Conditions: Obesity
Interventions: EMBER, Control; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 79 Years
Enrollment: 470 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 2
States / cities: Palo Alto, California • Houston, Texas

Conditions: Stress
Interventions: Mindfulness Compassion (MC), Mindfulness Gratitude (MG), Mindfulness Value-Based Living (MV); Behavioral
Lead sponsor: Sam Houston State University; Other
Eligibility: 18 Years and older
Enrollment: 126 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Huntsville, Texas

Conditions: Asthma
Interventions: SaMBA, Asthma Education - WTC Related; Behavioral
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 21 Years and older
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Post Traumatic Stress Disorder
Interventions: CPT Skills, Cognitive Processing Therapy, Present Centered Therapy, Shared Decision Making, Measurement Based Care; Behavioral
Lead sponsor: United States Department of Defense; Federal
Eligibility: 18 Years and older
Enrollment: 280 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 4
States / cities: Phoenix, Arizona • New Orleans, Louisiana • Charleston, South Carolina + 1 more

Conditions: Chronic Pain
Interventions: User guide with prompts; Behavioral
Lead sponsor: Washington State University; Other
Eligibility: 18 Years and older
Enrollment: 99 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 2
States / cities: Spokane, Washington

Conditions: Treatment Adherence
Interventions: Phone Coaching, Text Message Coaching, ACT Guide; Behavioral
Lead sponsor: Utah State University; Other
Eligibility: 18 Years and older
Enrollment: 236 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Logan, Utah

Conditions: Stroke Patients, CPAP, OSA - Obstructive Sleep Apnea
Interventions: CPAP device, CPAP technical support, Phone follow-up for adherence feedback and self-management skills, myAir, Tailored messages, Written Materials, Motivational Enhancement Therapy (MET); Device · Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 2
States / cities: Downey, California • Seattle, Washington

Conditions: Hearing Loss, Sensorineural
Interventions: Remote Microphone; Device
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 85 Years
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Evanston, Illinois

Conditions: Alcohol Use Disorder, Alcohol Drinking, Alcohol Abuse, Alcohol Dependence
Interventions: Contingency Management, Computer Based Training for Cognitive Behavioral Therapy for AUD (CBT4CBT); Behavioral
Lead sponsor: Washington State University; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Spokane, Washington

Conditions: Heart Failure, Pulmonary Disease, Chronic Obstructive, Emphysema, Pulmonary Fibrosis, Interstitial Lung Disease
Interventions: ADAPT Intervention; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 99 Years
Enrollment: 306 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2021
U.S. locations: 2
States / cities: Aurora, Colorado • Seattle, Washington

Conditions: Alcohol Use Disorder
Interventions: DynamiCare Rewards; Behavioral
Lead sponsor: DynamiCare Health; Industry
Eligibility: 18 Years and older
Enrollment: 61 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 2
States / cities: Centerville, Massachusetts • Falmouth, Massachusetts

Conditions: Binge Eating, Overweight and Obesity, Eating Disorders in Adolescence
Interventions: Cognitive-Behavioral Therapy for Adolescent Binge Eating, Lifestyle Behavioral Obesity Intervention, Active Control; Behavioral · Other
Lead sponsor: Indiana University; Other
Eligibility: 12 Years to 17 Years
Enrollment: 159 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Obesity and Overweight, Binge Eating Disorder
Interventions: Tirzepatide, Lisdexamfetamine Dimesylate, Guided self-help cognitive behavioral therapy, Placebo (oral), Placebo (injection); Drug · Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 105 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Obesity, Binge Eating Disorder
Interventions: Guided Self-Help, Pure Self-Help; Behavioral
Lead sponsor: Francine Rosselli; Other
Eligibility: 18 Years to 22 Years
Enrollment: 130 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 2
States / cities: Manchester, Connecticut • Middletown, Connecticut

Conditions: Type 1 Diabetes (T1D)
Interventions: Automated Insulin Delivery (AID), AIDANET + Fully Closed Loop (FCL), AIDANET + Anticipatory Closed Loop (ACL); Device
Lead sponsor: Sue Brown; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Smoking Cessation
Interventions: Stage-Tailored Manual, Stage Tailored Feedback Report, Moderate TTM-Tailored Feedback Report, Full TTM-Tailored Feedback Report, Enhanced TTM+Addiction Tailored Feedback Report; Behavioral
Lead sponsor: University of Rhode Island; Other
Eligibility: 18 Years and older
Enrollment: 3,006 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Kingston, Rhode Island

Search by objective public record fields.

Supported Online Self-Help for Veterans With Depression in Primary Care

The DigIT Trial: The Effectiveness and Implementation of a Coached Digital Insomnia Treatment Program in a Regional Healthcare System.

Evaluation Study of the Online High School Media Aware Program

The "Let's Talk Tech" Tool to Support Decision Making About Technology Use

INTEGRATE-D: A Pilot Test to Support Integration of Medical and Psychosocial Care for People With Type II Diabetes

Cognitive Training in Stroke Rehabilitation

Improving Transition Outcomes Through Accessible Health IT and Caregiver Support

HOBSCOTCH-YOUTH and Young Adults

The EMBER Trial for Weight Management Engagement

Two-Session Couples Class to Improve Relationship Health

NIOSH R21 WTC Asthma

Reducing Dropout and Improving Outcomes From PTSD Therapy: When to Switch Therapies or Stay the Course

Improving Activity in Adults With Chronic Pain With Online Resources

Pilot Evaluation of Peer-support Coaching to Increase Adherence to Online Self-help for College Mental Health

Stroke and CPAP Outcome Study 3 Randomized Controlled Trial

Remote Microphone Candidacy Study

Virtual Incentive Treatment for Alcohol

Advancing Symptom Alleviation With Palliative Treatment

Contingency Management for Alcohol Use Disorder

Cognitive and Behavioral Approaches to Reduce Binge Eating and Excess Weight in Adolescents (Online)

Efficacy and Safety of Tirzepatide Versus Placebo or Lisdexamfetamine Dimesylate for Binge-Eating Disorder

Binge Eating Self-help Treatment for University Students

Insulin Delivery With Self-Adjusting Closed-Loop and Behavioral Glycemic Control Enhanced by Prediction

Optimal TTM Tailoring for Population Cessation