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ClinicalTrials.gov public records Last synced Nov 5, 2026, 10:39 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1081–1104 of 1,581 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Self help Clear all

Conditions: Hearing Loss
Interventions: Comparison of PRO-FIT or SELF-FIT fitting; Device
Lead sponsor: Whisper.ai; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Survivors of Childhood Cancer, Substance Use
Interventions: WHO ASSIST v3.1 Screening with Feedback, ASSIST Linked Brief Intervention (10 Step Motivational interviewing (MI)/FRAMES), WHO ASSIST v3.1 Screening (No Feedback); Behavioral
Lead sponsor: St. Jude Children's Research Hospital; Other
Eligibility: 15 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Depression, Anxiety, Well-being
Interventions: The Common Elements Toolbox (COMET); Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 850 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Hearing Loss
Interventions: MDHearing smart hearing aid; Device
Lead sponsor: MDHearingAid; Industry
Eligibility: 18 Years and older
Enrollment: 91 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Mount Pleasant, Michigan

Conditions: Vaccination
Interventions: Girls OnGuard; Behavioral
Lead sponsor: Emory University; Other
Eligibility: 13 Years to 18 Years · Female only
Enrollment: 216 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2014
U.S. locations: 2
States / cities: Atlanta, Georgia • Decatur, Georgia

Conditions: Type 1 Diabetes
Interventions: FAMS-T1D, Digital resources for diabetes; Behavioral
Lead sponsor: University of Utah; Other
Eligibility: 18 Years to 24 Years
Enrollment: 280 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 2
States / cities: Los Angeles, California • Salt Lake City, Utah

Conditions: Smoking Cessation
Interventions: Non-invasive vagus nerve stimulator plus nicotine replacement patches, nicotine replacement patches; Combination Product · Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Geriatrics
Interventions: exoskeleton-based gait training; Device
Lead sponsor: Shirley Ryan AbilityLab; Other
Eligibility: 65 Years and older
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Covid19, SARS-CoV Infection, SARS-CoV-2, Corona Virus Infection
Interventions: Specimen Collection, Surveys; Diagnostic Test
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Insomnia
Interventions: Internet-based Self-help Insomnia Intervention; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 77 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Interventions: Mobile self-help intervention; Behavioral
Lead sponsor: Rush University Medical Center; Other
Eligibility: 16 Years to 25 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Fatigue
Interventions: Mindfulness-Based Stress Reduction, Attention Control; Behavioral
Lead sponsor: Indiana University; Other
Eligibility: 18 Years and older
Enrollment: 107 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 4
States / cities: Carmel, Indiana • Indianapolis, Indiana

Conditions: Anxiety and Mood Disorders
Interventions: Compassion Meditation (CM) intervention, Healthy Aging Psychoeducation; Behavioral · Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 55 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: San Diego, California

Conditions: Kidney Diseases
Interventions: Kidney Health Coaching, Usual Care; Other
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 2
States / cities: Atlanta, Georgia

Conditions: Substance Use Disorders, Alcohol Use Disorder, Stimulant-Related Disorder
Interventions: Cognitive Behavioral Therapy, Standard CBT; Device · Behavioral
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years to 65 Years · Male only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Gambling
Interventions: Referral to Gamblers Anonymous, Cognitive behavioral therapy, Cognitive behavioral self-help manual; Behavioral
Lead sponsor: UConn Health; Other
Eligibility: 18 Years and older
Enrollment: 231 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1998 – 2003
U.S. locations: 1
States / cities: Farmington, Connecticut

Conditions: Congestive Heart Failure
Interventions: self-paced instruction; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 95 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Hiv, Adherence, Medication
Interventions: PositiveLinks RX Mobile App, PositiveLinks RX Portal; Other
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Traumatic Brain Injury (TBI), Posttraumatic Stress Disorder (PTSD)
Interventions: CALM (Cognitive Apps for Life Management), Psychoeducation; Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Low Back Pain
Interventions: Medical Care, Dual Care, Shared Care; Other
Lead sponsor: Palmer College of Chiropractic; Other
Eligibility: 65 Years and older
Enrollment: 131 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 2
States / cities: Davenport, Iowa

Conditions: Smoking Cessation
Interventions: GENERIC, eTARGET; Behavioral
Lead sponsor: H. Lee Moffitt Cancer Center and Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 2,896 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Diabetes Mellitus, Cardiovascular Diseases
Interventions: Algorithm driven medication titration, Monitoring, Group support, Self efficacy; Other · Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 3
States / cities: West Haven, Connecticut • Honolulu, Hawaii • Providence, Rhode Island

Conditions: Pregnancy, Pregnancy, Complications, Pregnancy Outcomes
Interventions: MI MOM App; Behavioral
Lead sponsor: Michigan State University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 8
States / cities: Corunna, Michigan • Flint, Michigan • Gaylord, Michigan + 5 more

Conditions: Malignant Neoplasms of Mesothelial and Soft Tissue, Human Immunodeficiency Virus
Interventions: Screening Interview, Carbon Monoxide Test, Self-Help Materials, Visual Oral Screening Examination, Direct Fluorescent Oral Visualization Examination, Oral Biopsy; Behavioral · Device · Procedure
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2021
U.S. locations: 1
States / cities: Houston, Texas

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Clinical Trial Evaluating Outcomes of Self-Fit and Professionally Fit Hearing Aids

Feasibility of Incorporating a Standardized Substance Use Measure With Linked-Brief Intervention Into Routine Psychosocial Care of Adult Childhood Cancer Survivors

Online Wellness Intervention for College Students

Comparison of Hearing Aid Fitting Outcomes Between Self-fit and Professional Fit for MDHearing Smart Hearing Aids

Girls OnGuard: HPV Vaccination Uptake Among African American Adolescent Females

FAMS-T1D Self-Regulation and Social Support for T1D

A Study Of Vagal Nerve Stimulation In Conjunction With NRT For Smoking Cessation

Efficacy of Samsung GEMS-H Device Training in Older Adults

Epidemiologic Assessment of SARS-CoV-2 (COVID-19) Prevalence in Minnesota

Implementing and Evaluating Computer-Based Interventions for Mental Health: Testing an Implementation Strategy for VA Outpatient Care

Homeless Youth Study - Stepping Stone 2.0

Treatment for Persistently Fatigued Cancer Survivors: A Randomized Controlled Trial With Biomarker Response

Compassion Meditation for Older Adults

Collaborative Learning to Achieve Refined Interventions for Emory: Kidney Disease

A Randomized Controlled Trial of Digital CBT to Treat Addiction: Digital RITch®CBT vs. Standard CBT

Cognitive Behavioral Therapy for Treatment of Pathological Gambling

Developing and Assessing Competencies for Caregivers and Patients With Ventricular Assist Devices

Using Smart Phone Technology to Support HIV Medication Refill Adherence in Virginia

Cognitive Rehabilitation for Treatment of Anger in Veterans With TBI and PTSD

Collaborative Care for Older Adults With Back Pain (COCOA)

Smoking Cessation Self-Help for Dual Users of Tobacco Cigarettes and E-Cigarettes

Pharmacist-led Group Medical Visits to Help With Diabetes Management

Michigan Healthy Mom (MI-MOM) Pregnancy Improvement Web Application Trial

Non Invasive Oral Cancer Screening Among HIV Infected Individuals