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ClinicalTrials.gov public records Last synced Nov 6, 2026, 9:16 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1105–1128 of 1,582 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Self help Clear all

Conditions: Smoking Cessation
Interventions: Non-invasive vagus nerve stimulator plus nicotine replacement patches, nicotine replacement patches; Combination Product · Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Cystic Fibrosis
Interventions: Airway-clearance vest, Hyperpolarized Xe129; Procedure · Drug
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 12 Years to 21 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Osteoarthritis, Knee, Osteoarthritis, Hip, Avascular Necrosis, Rheumatoid Arthritis
Interventions: POPOP (preoperative patient optimization program), SOC (standard of care); Other
Lead sponsor: University of Arkansas; Other
Eligibility: 18 Years to 80 Years
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: Obesity
Interventions: Increase Fruits and Vegetables, Decrease Snack Foods, Increase Fruits and Vegetables and Decrease Snack Foods; Behavioral
Lead sponsor: The University of Tennessee, Knoxville; Other
Eligibility: 6 Years to 12 Years
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2025
U.S. locations: 2
States / cities: Knoxville, Tennessee

Conditions: Anxiety, Depressive Symptoms, Sleep Disturbance, Recurrent Disease, Fatigue, Quality of Life, Cancer
Interventions: Severe Anxiety/depression: High Intensity Stepped Care, Moderate Anxiety/depression: Low Intensity Stepped care, Enhanced Usual Care Control; Other
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 166
States / cities: Fort Smith, Arkansas • Fresno, California • Modesto, California + 129 more

Conditions: Pregnancy Related
Interventions: Standard Care with Well-Mama Intervention; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 15 Years to 49 Years · Female only
Enrollment: 576 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 2
States / cities: Baton Rouge, Louisiana • Newark, New Jersey

Conditions: Heart Failure, Asymptomatic Systolic Dysfunction
Interventions: Nesiritide, Placebo; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 37 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2013
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Treatment (ProudMe), Waitlist Control
Interventions: ProudMe, Waitlist Control; Behavioral
Lead sponsor: Louisiana State University and A&M College; Other
Eligibility: 10 Years to 15 Years
Enrollment: 480 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

Conditions: Eating Disorders, Obesity
Interventions: CoED Online Intervention; Behavioral
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Type 2 Diabetes
Interventions: Diabetes Empowerment Education Program; Other
Lead sponsor: Brittany L Smalls; Other
Eligibility: 18 Years to 99 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Hyden, Kentucky

Conditions: Disaster, PTSD, Adolescent Behavior, Trauma, Anxiety, Stress
Interventions: Sonoma Rises; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 13 Years to 17 Years
Enrollment: 7 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Transgender Adolescents & Young Adults
Interventions: Decision-aid; Behavioral
Lead sponsor: Ann & Robert H Lurie Children's Hospital of Chicago; Other
Eligibility: 8 Years to 24 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Insomnia, Traumatic Brain Injury
Interventions: Computerized Cognitive Behavioral Therapy for Insomnia; Behavioral
Lead sponsor: VA Eastern Colorado Health Care System; Federal
Eligibility: 18 Years to 60 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Young Adult, Cancer, Physical Activity
Interventions: Step-Up Intervention; Behavioral
Lead sponsor: University of Wisconsin, Milwaukee; Other
Eligibility: 18 Years to 39 Years
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 2
States / cities: Milwaukee, Wisconsin

Conditions: Asthma
Interventions: Group A - Patient Education, Group B - Patient Education with Nutrition Counseling; Behavioral
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 18 Years and older
Enrollment: 323 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 2
States / cities: Chicago, Illinois

Conditions: Colorectal Cancer
Interventions: Brochure regarding sedentary behavior; Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Smoking Cessation, Medication Adherence
Interventions: Varenicline, Cognitive-behavioral self-help, MyMAP (My Mobile Advice Program); Drug · Behavioral
Lead sponsor: Kaiser Permanente; Other
Eligibility: 18 Years to 65 Years
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Cancer, Survivorship, Depression, Anxiety
Interventions: Telemental Health Sessions, Support Groups and Questionnaires; Behavioral
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years to 39 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Suicide, Suicidal Ideation, Suicidal Intention, Suicidal and Self-injurious Behavior
Interventions: Intergenerational Knowledge Sharing group, Support group; Behavioral
Lead sponsor: University of New Mexico; Other
Eligibility: 13 Years to 24 Years
Enrollment: 222 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Breast Cancer, Physical Activity
Interventions: Aerobic Training - Fixed Schedule, Resistance Training - Fixed Schedule, Walking program, Aerobic Training - Flexible Schedule, Resistance Training - Flexible Schedule, Successful Survivorship Health Education and Support Group, Flexible support groups; Behavioral
Lead sponsor: Case Comprehensive Cancer Center; Other
Eligibility: 65 Years and older · Female only
Enrollment: 218 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 3
States / cities: Cleveland, Ohio

Conditions: Obesity
Interventions: Health Smart for Weight Loss; Behavioral
Lead sponsor: University of Florida; Other
Eligibility: 21 Years to 100 Years · Female only
Enrollment: 683 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Chronic Pain
Interventions: STEPS Intervention; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 60 Years and older
Enrollment: 57 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Advanced Cancers
Interventions: Edmonton Symptom Assessment Scale, Interview; Behavioral
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 138 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Diabetes
Interventions: TEAMcare treatment of diabetes; Other
Lead sponsor: University of Washington; Other
Eligibility: 18 Years to 70 Years
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Seattle, Washington

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A Study Of Vagal Nerve Stimulation In Conjunction With NRT For Smoking Cessation

Regional Monitoring of CF Lung Disease

Impact of a POPOP on Preoperative Health, Eligibility, and Clinical & Patient-Reported Outcomes in TJA

The Effect of Three Different Dietary Messages on Dietary Intake and Health in Families

Stepped-Care Telehealth for Distress in Cancer Survivors

Well-Mama Community Doula Navigator Study

Human B-type Natriuretic Peptide (BNP) (Nesiritide) to Help Heart, Kidney, and Hormonal Functions in Persons With Lower Heart Pumping Function

Dissemination of an Adolescent Obesity Prevention Intervention to Louisiana Schools

Combined Eating Disorder and Weight Loss Online Guided-Self Help Intervention

Social Support Intervention for Older Adults With T2DM

Feasibility and Efficacy of a Digital Mental Health Intervention for Teen Wildfire Survivors

Fertility Decision-Making in Youth and Young Adults

University of Colorado - Restoring Efficient Sleep After TBI

Step-Up Intervention for Self-Management of Fatigue in Young Adults Receiving Chemotherapy

Addressing Quality of Life, Clinical Outcomes, and Mechanisms in Uncontrolled Asthma Following the DASH Dietary Pattern

Reducing Sedentary Behaviors Among Colorectal Cancer Survivors

My Mobile Advice Program: A Randomized Pilot Feasibility Study

Cancer Within a Pandemic: A Telemental Health Intervention

Zero Suicide Plus KICKS

Physical Activity Intervention to Reduce Functional Health Disparities Among Breast Cancer Survivors

Health-Smart for Weight Loss at UF Jax Clinics

Tracking Physical Activity for Chronic Pain Management Among Older Adults in Detroit

Edmonton Symptom Assessment Scale: Self-Completion vs. Assisted-Completion

TEAMcare for Diabetes in Mental Health Centers