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ClinicalTrials.gov public records Last synced Nov 6, 2026, 10:07 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1129–1152 of 1,582 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Self help Clear all

Conditions: Alcohol Abuse, Alcohol Use Disorder, Alcohol Drinking, Relations, Interpersonal, Military Family
Interventions: CRAFT Web-Based Intervention, Phone-Based CRAFT, CRAFT Workbook, Gottman Self-Guided Resources; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 744 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Menopausal Women, Insomnia
Interventions: Cognitive behavioral therapy for insomnia (CBT-i), Trazodone, Daridorexant; Behavioral · Drug
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 40 Years to 62 Years · Female only
Enrollment: 1,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 5
States / cities: Boston, Massachusetts • Novi, Michigan • Winston-Salem, North Carolina + 2 more

Conditions: Smoking Cessation, Smoking, Cigarette, Smoking Reduction, Smoking, Smoking, Tobacco, Quitting Smoking
Interventions: 4 weeks of Nicotine lozenge, 8 weeks of Nicotine Replacement Therapy Patch, QuitAid, Smokefree TXT, Tobacco Quitline, 4 weeks of Nicotine Replacement Therapy Patch, 8 Weeks Nicotine Lozenge; Drug · Behavioral
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years and older
Enrollment: 768 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Peripheral Arterial Disease
Interventions: Smartphone-enabled structured exercise therapy (SE-SET), Standard exercise therapy; Behavioral
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 89 Years
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2025
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Nicotine Dependence
Interventions: Behavioral Counseling, Self-help control; Behavioral
Lead sponsor: Temple University; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2011
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Tobacco Cessation
Interventions: Written self-help materials, Group behavioral counseling; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 12 Years to 17 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Bethel, Alaska

Conditions: Smoking Cessation
Interventions: Telephone counseling, Voucher, Nicotine patches; Behavioral · Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 3,706 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: San Diego, California

Conditions: Suicide, Suicide, Attempted, Hospitals, Psychiatric
Interventions: Crisis Line Facilitation (CLF), Enhanced Usual Care (EUC); Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 99 Years
Enrollment: 307 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 2
States / cities: Ann Arbor, Michigan • Battle Creek, Michigan

Conditions: Inherited Retinal Diseases
Interventions: Low Vision Rehabilitation (LVR), Emotion Regulation Therapy (ERT); Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: COPD (Chronic Obstructive Pulmonary Disease)
Interventions: COPD Wellness, COPD Wellness Plus+, Usual Care; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 40 Years to 90 Years
Enrollment: 387 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 3
States / cities: San Francisco, California

Conditions: Refractory Epilepsy
Interventions: HOBSCOTCH: "Home-Based Self-Management and Cognitive Training Changes Lives"; Behavioral
Lead sponsor: Kessler Foundation; Other
Eligibility: 18 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: East Hanover, New Jersey

Conditions: Chronic Low Back Pain
Interventions: Intervention, No intervention; Behavioral · Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 27 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Caregiver Burden, Caregiver Stress Syndrome, Caregiver Burnout
Interventions: TBI-AD/ADRD Caregiver Support Intervention (TACSI); Other
Lead sponsor: University of Minnesota; Other
Eligibility: 21 Years and older
Enrollment: 95 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Hypertension, Type 2 Diabetes Mellitus (T2DM)
Interventions: Coach-Directed Tailored DASH Groceries Plus Lifestyle Intervention, Self-Shopping DASH diet advice; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Cancer, Cancer-related Problem/Condition, Exercise
Interventions: Yoga, Stretching and Toning, Aerobic Walking; Behavioral
Lead sponsor: University of Illinois at Urbana-Champaign; Other
Eligibility: 30 Years to 70 Years
Enrollment: 78 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Urbana, Illinois

Conditions: Sedentary Lifestyle
Interventions: ActivPAL inclinometer, Phone counseling call: Breaking up sitting time, In-person counseling: Breaking up sitting time, Phone counseling call: Healthy living, Tools to prompt standing, In-person counseling: Healthy living; Device · Behavioral · Other
Lead sponsor: University of California, San Diego; Other
Eligibility: 55 Years and older · Female only
Enrollment: 254 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2022
U.S. locations: 2
States / cities: Chula Vista, California • San Diego, California

Conditions: Cigarette Smoking
Interventions: Mindfulness-Based Addiction Treatment, Nicotine Replacement Therapy, Self-help materials, iQuit Mindfully; Behavioral · Drug
Lead sponsor: Georgia State University; Other
Eligibility: 18 Years and older
Enrollment: 504 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Stress
Interventions: Mindfulness Compassion (MC), Mindfulness Gratitude (MG), Mindfulness Value-Based Living (MV); Behavioral
Lead sponsor: Sam Houston State University; Other
Eligibility: 18 Years and older
Enrollment: 126 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Huntsville, Texas

Conditions: Loss of Control Eating
Interventions: Standard-of-Care, Behavioral Weight Loss Treatment, Cognitive Behavioral Therapy; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Hypertension
Interventions: Telemedicine management of Hypertension, Usual Care; Behavioral
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Chronic Kidney Disease, End-Stage Renal Disease
Interventions: Medication Information Transfer Intervention, Usual care for hospital discharge; Other
Lead sponsor: Providence Medical Research Center; Other
Eligibility: 21 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Spokane, Washington

Conditions: IBS - Irritable Bowel Syndrome
Interventions: Use of Zemedy Application; Device
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Redwood City, California

Conditions: Autism Spectrum Disorder, Autism, Autism Spectrum Disorders, Autistic Disorder, Autistic Spectrum Disorder, Autistic Spectrum Disorders, Autistic Disorders Spectrum
Interventions: Autism Family Empowerment Coaching and Training Program; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 12 Months to 60 Months
Enrollment: 143 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 2
States / cities: Atherton, California • Sunnyvale, California

Conditions: Mental Disorders
Interventions: activation curriculum, support group; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: Not listed
Enrollment: 181 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Search by objective public record fields.

A SMART Evaluation of an Adaptive Web-based AUD Treatment for Service Members and Their Partners

Comparing Digital Therapy, Trazodone, and Daridorexant for Menopause-Related Insomnia Symptoms

Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in Appalachia

Smartstep Smartphone PAD

Counseling to Reduce Children's SHS Exposure: A Trial With Maternal Smokers

Tobacco Cessation Treatment for Alaska Native Youth

Providing Free Nicotine Patches to Quitline Smokers

Crisis Line Facilitation

Optimizing Low Vision Rehabilitation in Emotionally Distressed Patients With Inherited Retinal Diseases

Rehabilitation in Safety-net Environments (RISE) to Improve Outcomes in Vulnerable Patients With COPD

Feasibility of HOBSCOTCH Telehealth Intervention in Refractory Epilepsy

Reducing Sedentary Behavior to Decrease Low Back Pain: Stand Back Study

Traumatic Brain Injury and Alzheimer's Disease/Related Dementias Caregiver Support Intervention

Groceries Plus Multi-Component Lifestyle Intervention for Adults With Hypertension and Type 2 Diabetes

Effects of Yoga, Strength Training and Aerobic Exercise on Cognition in Adult Cancer Survivors

Trial to Reduce Sitting Time in Postmenopausal Latina Women at Increased Risk for Heart Disease

Mindfulness-based Smoking Cessation Enhanced With Mobile Technology

Two-Session Couples Class to Improve Relationship Health

Loss of Control Eating Following Weight Loss Surgery

Tailoring TM-HTN Intervention for Black Patients

Medication Intervention in Transitional Care to Optimize Outcomes & Costs for CKD & ESRD

Zemedy Application for Irritable Bowel Syndrome

Project AFECT (Autism Family Empowerment Coaching and Training Program)

Padres Efectivos (Parent Activation): Skills Latina Mothers Use to Get Healthcare for Their Children