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Showing 1–24 of 46 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Self-Guided Lifestyle Intervention Clear all
Completed Not applicable Interventional

Financial Coaching and Lifestyle Intervention for Diabetes Prevention in Low-income Families

NCT05944549
View directory record Official record
Conditions
Weight Loss
Interventions
Financial coaching using TrustPlus, Brighter Bites, Noom
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 8, 2025 · Synced Sep 25, 2026, 5:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Girl2Girl: Harnessing Text Messaging to Reduce Teenage Pregnancy Among LGB Girls

NCT03029962
View directory record Official record
Conditions
Teenage Pregnancy
Interventions
Girl2Girl
Behavioral
Lead sponsor
Center for Innovative Public Health Research
Other
Eligibility
14 Years to 18 Years · Female only
Enrollment
948 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
San Clemente, California
Source: ClinicalTrials.gov public record
Updated Mar 15, 2021 · Synced Sep 25, 2026, 5:31 PM EDT
Recruiting Not applicable Interventional

Preconception Intervention for Incarcerated Women With Substance Use

NCT05854836
View directory record Official record
Conditions
Substance Use Disorders
Interventions
CHOICES-PLEAS (Pregnancy Liberated from Exposure to Alcohol and Substances)
Behavioral
Lead sponsor
St. Louis University
Other
Eligibility
18 Years to 49 Years · Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Sep 25, 2026, 5:31 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Pilot Factorial Trial of an Integrated Lifestyle Intervention

NCT06116435
View directory record Official record
Conditions
Physical Inactivity, Overweight and Obesity
Interventions
Prevent T2, Move group-based classes, Fitness Membership, Mental Imagery, Move 1:1 Support
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 13, 2024 · Synced Sep 25, 2026, 5:31 PM EDT
Completed Not applicable Interventional

Bariatric Scalable Internet Treatments

NCT03680703
View directory record Official record
Conditions
Bariatric Surgery, Weight Loss
Interventions
Guided Self-Help Behavioral Weight Loss
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 70 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 6, 2020 · Synced Sep 25, 2026, 5:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

U.S. Study to Protect Brain Health Through Lifestyle Intervention to Reduce Risk

NCT03688126
View directory record Official record
Conditions
Alzheimer Disease
Interventions
Self-Guided Lifestyle Intervention, Structured Lifestyle Intervention
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
60 Years to 79 Years
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
6
States / cities
Sacramento, California • Chicago, Illinois • Downers Grove, Illinois + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 2, 2025 · Synced Sep 25, 2026, 5:31 PM EDT
Recruiting Not applicable Interventional

ME/CFS Brain Fog: Cognitive Rehabilitation Trial

NCT07523113
View directory record Official record
Conditions
ME/CFS, ME/CFS Following EBV-associated Infectious Mononucleosis, ME/CFS Following COVID-19, Chronic Fatigue, Chronic Fatigue Syndrome (CFS), Brain Fog, Cognitive Impairment, Cognitive Dysfunction
Interventions
Processing Speed Training, In-session Instrumental Activities of Daily Living Training, Transfer Package, Follow Up Phone Calls, Trans-auricular Vagus Nerve Stimulation: High Intensity, In-session Brain Health Training, Reaction Time Training, Trans-auricular Vagus Nerve Stimulation: Low Intensity
Behavioral · Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 25, 2026, 5:31 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

ENGAGED: E-Networks Guiding Adherence to Goals for Exercise and Diet

NCT01051713
View directory record Official record
Conditions
Obesity
Interventions
Technology Supported, Standard
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 10, 2016 · Synced Sep 25, 2026, 5:31 PM EDT
Not yet recruiting Not applicable Interventional

Addressing Food Access and Physical Activity to Improve Diabetes Prevention Outcomes Among Underserved African Americans

NCT07560969
View directory record Official record
Conditions
Diabetes, Physical Activity, Food Security, Nutrition Security
Interventions
Culturally-tailored, enhanced adaption of Diabetes Prevention Program
Behavioral
Lead sponsor
University of Missouri, Kansas City
Other
Eligibility
18 Years and older
Enrollment
408 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2031
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 25, 2026, 5:31 PM EDT
Recruiting Not applicable Interventional

Long COVID Brain Fog: Cognitive Rehabilitation Trial

NCT06095297
View directory record Official record
Conditions
Long COVID, Brain Fog, Cognitive Impairment, Cognitive Dysfunction, Post-Acute COVID-19 Syndrome
Interventions
Processing Speed Training, In-lab Instrumental Activities of Daily Living Training, In-lab Brain Health Training, Transfer Package, Follow Up Phone Calls, Vocational Rehabilitation, Peer Mentoring, Reaction Time Training, Trans-auricular Vagus Nerve Stimulation: High Intensity, Trans-auricular Vagus Nerve Stimulation: Low Intensity
Behavioral · Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 25, 2026, 5:31 PM EDT
Active, not recruiting Not applicable Interventional

Creating a Healthy L.I.F.E: Lifestyle Interventions For Epilepsy

NCT05283200
View directory record Official record
Conditions
Lifestyle
Interventions
Yoga, Cognitive Behavioral Therapy, Music
Behavioral
Lead sponsor
Imad Najm MD
Other
Eligibility
18 Years to 75 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Sep 25, 2026, 5:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Patient-Directed Lifestyle Change and Health Promotion Program or Usual Care in Low-Income, Uninsured Participants in Los Angeles County, California

NCT00521209
View directory record Official record
Conditions
Impoverished Population
Interventions
Self-Care Stimulating Disease Prevention Program (SCSDPP), Stand procedures, no intervention
Behavioral · Other
Lead sponsor
Jonsson Comprehensive Cancer Center
Other
Eligibility
18 Years to 120 Years
Enrollment
97 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 7, 2023 · Synced Sep 25, 2026, 5:31 PM EDT
Recruiting Not applicable Interventional

Active Living After Cancer: Implementation Within Be Well Acres Homes

NCT06907706
View directory record Official record
Conditions
Cancer, Fatigue
Interventions
Physical Activity/Physical Functioning, Quality of Life
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Sep 25, 2026, 5:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Video Chat Intervention for Enhancing Self-efficacy for Lifestyle Physical Activity

NCT03906955
View directory record Official record
Conditions
Physical Activity, Self Efficacy, Working Adults
Interventions
Efficacy for Lifestyle PA, Efficacy for Work-life Balance
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
25 Years to 64 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Champaign, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 23, 2019 · Synced Sep 25, 2026, 5:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mediterranean Diet and Weight Loss: Targeting the Bile Acid/Gut Microbiome Axis to Reduce Colorectal Cancer

NCT04753359
View directory record Official record
Conditions
Colorectal Cancer, Diet Habit
Interventions
Med, WL
Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
45 Years to 75 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Sep 25, 2026, 5:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mind-body Interventions for Healthy Aging

NCT03626532
View directory record Official record
Conditions
Aging
Interventions
Mindfulness-Based Stress Reduction (MBSR), Lifestyle Education (LifeEd)
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
65 Years to 85 Years
Enrollment
173 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 30, 2023 · Synced Sep 25, 2026, 5:31 PM EDT
Recruiting Not applicable Interventional

HTN App for HTN Control and Cardiovascular Health Among African-Americans

NCT06346886
View directory record Official record
Conditions
Hypertension
Interventions
FAITH! HTN app
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 25, 2026, 5:31 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Test of Target Engagement of Ambiguity Aversion

NCT06962527
View directory record Official record
Conditions
Intolerance of Uncertainty, Anxiety, Intolerance of Uncertainty; Anxiety, Depression, Anxiety
Interventions
Uncertainty-focused single session intervention, Maintaining a healthy lifestyle single session intervention
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
25 Years to 60 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Sep 25, 2026, 5:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Passport to Brain Wellness in Sedentary Adults

NCT00979446
View directory record Official record
Conditions
Mild Cognitive Impairment, Alzheimer's Disease
Interventions
Guided, Self-directed
Behavioral
Lead sponsor
HealthPartners Institute
Other
Eligibility
60 Years to 80 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 17, 2009 · Synced Sep 25, 2026, 5:31 PM EDT
Terminated Not applicable Interventional Results available

PACESETTER: Program to Avoid Cerebrovascular Events Through Systematic Electronic Tracking and Tailoring of an Eminent Risk-factor

NCT03401489
View directory record Official record
Conditions
Blood Pressure, Hypertension, Mhealth
Interventions
PACESETTER
Device
Lead sponsor
Northern California Institute of Research and Education
Other
Eligibility
18 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
4
States / cities
San Francisco, California • Charleston, South Carolina • Columbia, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Sep 25, 2026, 5:31 PM EDT
Terminated Not applicable Interventional

Mindfulness-Based Stress Reduction Versus Lifestyle Intervention for Long-Haul Covid-19 Parosmia

NCT06789952
View directory record Official record
Conditions
COVID-19
Interventions
Mindfulness-Based Stress Reduction, Lifestyle Intervention
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 22, 2025 · Synced Sep 25, 2026, 5:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy of Two Novel Behavioral Post-cessation Weight Gain Interventions

NCT03156660
View directory record Official record
Conditions
Weight Change, Body, Smoking Cessation
Interventions
Weight gain prevention (Group 1), Weight loss intervention (Group 2), Self-guided intervention (Group 3)
Behavioral
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
305 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 20, 2023 · Synced Sep 25, 2026, 5:31 PM EDT
Active, not recruiting Not applicable Interventional

Brain Boosters 2 in Persons at Risk for Alzheimer's Disease: a Digital Application Supported Intervention

NCT05027789
View directory record Official record
Conditions
Memory Disorders, Cognitive Impairment
Interventions
Self-Guided, Structured Group
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
65 Years to 90 Years
Enrollment
263 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced Sep 25, 2026, 5:31 PM EDT
Recruiting Not applicable Interventional

Health Behavior Intervention for Adults With Type 1 Diabetes

NCT05823142
View directory record Official record
Conditions
Type1diabetes
Interventions
CB Sleep
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years to 40 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Sep 25, 2026, 5:31 PM EDT