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Showing 481–504 of 1,836 matching trials from the live ClinicalTrials.gov search.
Completed Phase 2 Interventional Results available

Tafenoquine in Patients With Mild to Moderate COVID-19

NCT04533347
Conditions
COVID 19 Disease
Interventions
Tafenoquine Oral Tablet, Placebo
Drug
Lead sponsor
60 Degrees Pharmaceuticals LLC
Industry
Eligibility
18 Years and older
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
10
States / cities
Miami, Florida • Elkhorn, Nebraska • Morgantown, North Carolina + 4 more
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Collaborative Care for Alcohol Use Disorders in the Patient-centered Medical Home

NCT02885311
Conditions
Alcohol-Related Disorders, Alcohol Drinking, Alcoholism, Alcohol Abuse, Alcohol Use Disorders
Interventions
Motivation Enhancement Therapy, Modified Behavioral Self-Control Therapy, Naltrexone, Brief Advice, Referral to specialty substance use disorder treatment
Behavioral · Drug · Other
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 75 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Great Neck, New York
Conditions
COVID-19
Interventions
Rivaroxaban, Placebo
Drug
Lead sponsor
Gates Medical Research Institute
Other
Eligibility
18 Years and older
Enrollment
497 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
17
States / cities
Rogers, Arkansas • Los Angeles, California • San Diego, California + 14 more
Conditions
Polycythemia Vera
Interventions
Ruxolitinib, Hydroxyurea (HU), HU-placebo, Ruxolitinib-placebo
Drug
Lead sponsor
Incyte Corporation
Industry
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
51
States / cities
Scottsdale, Arizona • Fayetteville, Arkansas • Burbank, California + 48 more
Conditions
Bipolar Disorder
Interventions
Weekly review, No weekly review
Behavioral · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
Ann Arbor, Michigan • Madison, Wisconsin
Conditions
Alcohol Drinking, Veterans
Interventions
Cognitive Behavioral Therapy (CBT), Mobile Contingency Management (mCM), Long-term incentive
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Squamous Cell Carcinoma of Head and Neck
Interventions
NDURE
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Completed Not applicable Interventional Results available

Brief Behavioral Treatment for Insomnia in Cancer Survivors

NCT03810365
Conditions
Chronic Insomnia
Interventions
Brief behavioral treatment for insomnia, Healthy Eating Control
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Buffalo, New York
Conditions
Type 2 Diabetes Mellitus
Interventions
Insulin glargine /lixisenatide Fixed Ratio Combination, Insulin glargine, Metformin (Background drug)
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older
Enrollment
323 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
14
States / cities
Little Rock, Arkansas • Paramount, California • Larenceville, Georgia + 11 more
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Effectiveness of the Adapt for Life, Mental Wellness and Suicide Prevention Program

NCT06979479
Conditions
Depression Disorders, Suicidality
Interventions
school-based intervention
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Not listed
Enrollment
1,102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Rectal Cancer, Self Efficacy
Interventions
PATHWAYS, Enhanced usual care
Behavioral · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
2
States / cities
Boston, Massachusetts
Conditions
Aortic Stenosis
Interventions
ACURATE neo2™ Transfemoral TAVR System, Medtronic CoreValve TAVR System, Edwards SAPIEN 3 TAVR System, ACURATE Prime™ Transfemoral TAVR System XL
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
Not listed
Enrollment
1,948 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2029
U.S. locations
69
States / cities
Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 58 more
Conditions
Moderate Gastrointestinal Discomfort
Interventions
BIOHM FX Probiotic Blend
Dietary Supplement
Lead sponsor
Biohm Technologies
Industry
Eligibility
18 Years to 75 Years
Enrollment
141 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Lung Cancer, Gastric Cancer, Pancreatic Cancer
Interventions
Testing an interactive technology in a diverse health literary population
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Asthma in Children
Interventions
AsthmaTuner, Asthma-Guidance and Prediction System
Device · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
6 Years to 17 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Rochester, Minnesota
Completed No phase listed Observational Accepts healthy volunteers

Health Risks and Barriers to Management Across the PCOS Lifespan

NCT05769426
Conditions
Polycystic Ovary Syndrome, Menopause
Interventions
Not listed
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years and older · Female only
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Galveston, Texas
Conditions
Treatment-resistant Depression
Interventions
Esketamine (Intranasal Spray), Duloxetine (Oral Antidepressant), Escitalopram (Oral Antidepressant), Sertraline (Oral Antidepressant), Venlafaxine Extended Release (XR) (Oral Antidepressant)
Drug
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
18 Years and older
Enrollment
802 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
16
States / cities
New Haven, Connecticut • Miami, Florida • Marietta, Georgia + 13 more
Completed Not applicable Interventional Accepts healthy volunteers

Engineering an Online STI Prevention Program: CSE2

NCT03408743
Conditions
Alcohol Consumption, Sexually Transmitted Diseases
Interventions
Knowledge Alone, Self-efficacy alone, Perceived benefits alone, Benefits and self-efficacy, Injunctive norms alone, Injunctive norms and self-efficacy, Injunctive norms and benefits, Injunctive norms, benefits, self-efficacy, Descriptive norms alone, Descriptive norms and self-efficacy, Descriptive norms and perceived benefits, Descriptive norms, benefits, self-efficacy, Descriptive norms and injunctive norms, Descriptive and injunctive norms, self-efficacy, Descriptive and injunctive norms, and benefits, Descriptive & injunctive norms, benefits, efficacy, Expectancies alone, Expectancies and self-efficacy, Expectancies and perceived benefits, Expectancies, benefits, self-efficacy, Expectancies and injunctive norms, Expectancies, injunctive norms, self-efficacy, Expectancies, injunctive norms, and benefits, Expectancies, injunctive norms, benefits, efficacy, Expectancies and descriptive norms, Expectancies, descriptive norms, & self-efficacy, Expectancies, descriptive norms, benefits, Expectancies, descriptive norms, benefits, efficacy, Expectancies, descriptive and injunctive norms, Expectancies, descriptive & injunctive norms, efficacy, Expectancies, descriptive & injunctive norms, benefits, Expectancies, descriptive & injunctive, benefits, efficacy
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 30 Years
Enrollment
2,946 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
4
States / cities
Fresno, California • Fargo, North Dakota • Murfreesboro, Tennessee + 1 more
Conditions
Overweight and Obesity, Weight Loss Maintenance, Dietary Habits
Interventions
Weight Loss Maintenance (Control vs. Reverse Diet)
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
21 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Aurora, Colorado
Not listed Not applicable Interventional Accepts healthy volunteers

Health Behavior Change in Midlife Adults at Risk for Alzheimer's Disease

NCT05599425
Conditions
Alzheimer Disease
Interventions
Enhanced Healthy Living Education, Basic Healthy Living Education
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
45 Years to 69 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Conditions
Cataract
Interventions
Clobetasol Propionate, Vehicle
Drug
Lead sponsor
Salvat
Industry
Eligibility
18 Years and older
Enrollment
215 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
18
States / cities
Sun City, Arizona • Hemet, California • Inglewood, California + 15 more
Conditions
Prader-Willi Syndrome, Aggression, Self-Injurious Behavior, Pathologic Processes, Behavioral Symptoms, Intellectual Disability, Neurobehavioral Manifestations, Neurologic Manifestations, Nervous System Diseases, Abnormalities, Multiple, Congenital Abnormalities, Chromosome Disorders, Genetic Diseases, Inborn, Obesity, Overnutrition, Nutrition Disorders, Antihypertensive Agents, Neurotransmitter Agents, Molecular Mechanisms of Pharmacological Action, Physiological Effects of Drugs, Skin-Picking
Interventions
Guanfacine Extended Release, Placebo
Drug · Other
Lead sponsor
Maimonides Medical Center
Other
Eligibility
6 Years to 35 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Brooklyn, New York
Completed Not applicable Interventional Accepts healthy volunteers

Tailoring of Vaccine-Focused Messages: Disease Salience

NCT03002324
Conditions
Human Papillomavirus
Interventions
Baseline Survey, Current CDC Message, Cervical Cancer Message, Control Message, Post-Intervention Survey
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
1,320 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Diabetes Mellitus, Type 2, Lifestyle, Hyperglycemia, Physical Inactivity
Interventions
Focused App Prompt, No App Prompt
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
14 Years to 26 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania