Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 14, 2026, 12:58 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 361–384 of 517 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sepsis Clear all

Conditions: Systemic Inflammatory Response Syndrome
Interventions: Azithromycin on admission - not enrolled in the RCT; Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2013
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Sepsis
Interventions: Sepsis Transition and Recovery (STAR) program, Usual care; Behavioral
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 3,894 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Charlotte, North Carolina

Conditions: Sepsis, Blood Pressure
Interventions: Midodrine Hydrochloride 10 milligrams, Placebo capsule; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Sepsis, Severe Sepsis
Interventions: Not listed
Lead sponsor: Christiana Care Health Services; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 4
States / cities: Denver, Colorado • Newark, Delaware • Billings, Montana + 1 more

Conditions: Sepsis, Sepsis Bacterial, Lactate Blood Increase, Infectious Disease
Interventions: Lab Clasp; Device
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 6 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Septic Shock
Interventions: Simvastatin, Placebo; Drug
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Bloodstream Infection
Interventions: 70% ethanol, heparin flush solution; Drug
Lead sponsor: Baystate Medical Center; Other
Eligibility: 6 Months to 23 Years
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Springfield, Massachusetts

Conditions: Stroke, Acute
Interventions: BrainPulse Device; Device
Lead sponsor: Jan Medical, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 252 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2024
U.S. locations: 3
States / cities: Arlington Heights, Illinois • Evanston, Illinois • Cincinnati, Ohio

Conditions: Premature Birth of Newborn, Enterocolitis, Necrotizing
Interventions: Ampicillin, Gentamicins, Placebo; Drug
Lead sponsor: University of Chicago; Other
Eligibility: Up to 6 Hours
Enrollment: 27 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Sepsis
Interventions: Conservative Fluid Management Strategy; Other
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Sepsis
Interventions: piperacillin-tazobactam; Drug
Lead sponsor: Phillip Brian Smith; Other
Eligibility: Up to 60 Days
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 4
States / cities: Indianapolis, Indiana • Wichita, Kansas • Kansas City, Missouri + 1 more

Conditions: Severe Sepsis
Interventions: eritoran tetrasodium, Placebo; Drug
Lead sponsor: Eisai Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 2,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2006
U.S. locations: 69
States / cities: Birmingham, Alabama • Mobile, Alabama • Mesa, Arizona + 66 more

Conditions: Sepsis-associated Acute Kidney Injury
Interventions: Not listed
Lead sponsor: Novartis Pharmaceuticals; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: East Hanover, New Jersey

Conditions: Cytoreductive Surgery
Interventions: Serum procalcitonin lab draws; Other
Lead sponsor: Eastern Regional Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Nephrolithiasis, Urinary Tract Infection (UTI), Sepsis
Interventions: Nitrofurantoin 100 MG, 7d, Gentamicin, 5mg/kg, Ampicillin 2g, Nitrofurantoin 100 mg, 48 hrs, Gentamicin, 80 mg, 7d, Gentamicin, 80 mg, 48hr; Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: Not listed
Enrollment: 330 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2025
U.S. locations: 1
States / cities: San Diego, California

Conditions: Sepsis, Septic Shock
Interventions: vasopressin - early initiation, vasopressin - standard initiation; Drug
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Acute Kidney Injury, Peritonitis, Necrotizing Soft Tissue Infection
Interventions: Reltecimod 0.5 mg/kg, Placebo; Drug
Lead sponsor: Atox Bio Ltd; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 58 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 40
States / cities: Phoenix, Arizona • Tucson, Arizona • Little Rock, Arkansas + 33 more

Conditions: Sepsis, Shock, Septic, Sepsis Syndrome, Septicemia, Infection
Interventions: E5564; Drug
Lead sponsor: Eisai Inc.; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2005
U.S. locations: 17
States / cities: Mobile, Alabama • San Diego, California • Santa Barbara, California + 14 more

Conditions: Sepsis
Interventions: No Intervention: Observational Cohort; Other
Lead sponsor: University of British Columbia; Other
Eligibility: 5 Years to 16 Years
Enrollment: 4,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 3
States / cities: San Francisco, California • Ithaca, New York • Seattle, Washington

Conditions: Sepsis
Interventions: Metoclopramide, Zinc, Glutamine, Selenium, saline, sterile water, selenium, whey-protein; Drug · Dietary Supplement · Other
Lead sponsor: Michael Dean; Other
Eligibility: 12 Months to 17 Years
Enrollment: 293 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 7
States / cities: Little Rock, Arkansas • Los Angeles, California • Washington D.C., District of Columbia + 3 more

Conditions: Necrotizing Enterocolitis, Sepsis
Interventions: Fortified Pasteurized Donor Human Milk supplement, Preterm Formula supplement; Behavioral
Lead sponsor: National Center for Research Resources (NCRR); NIH
Eligibility: 0 Years to 96 Hours
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 1997
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Sepsis, Adult Disease, Severe Sepsis, Emergency Department
Interventions: CBC-DIFF Monocyte Volume Width Distribution (MDW); Diagnostic Test
Lead sponsor: Beckman Coulter, Inc.; Industry
Eligibility: 18 Years to 89 Years
Enrollment: 1,139 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Severe Sepsis, Septic Shock
Interventions: Modified EGDT, Standard EGDT; Procedure
Lead sponsor: National Institute of General Medical Sciences (NIGMS); NIH
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 3
States / cities: Boston, Massachusetts • Camden, New Jersey • Charlotte, North Carolina

Conditions: Sepsis, Non-Infectious Systemic Inflammatory Response Syndrome
Interventions: SeptiCyte (various); Diagnostic Test
Lead sponsor: Seattle Children's Hospital; Other
Eligibility: 1 Month to 17 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 2
States / cities: Seattle, Washington

Search by objective public record fields.

Efficacy of Macrolide Immunomodulation in Severe Sepsis.

Implementation and Effectiveness of Engagement and Collaborative Management to Proactively Advance Sepsis Survivorship

Midodrine Hydrochloride in Early Sepsis

The AVERT Sepsis Investigation

A Validation Study of the Lab Clasp Device: A Point of Care Sepsis Risk Monitor

Statin Therapy in the Treatment of Sepsis

Ethanol Locks for the Treatment of Central Venous Line Infections

Pilot Study of Acute Stroke Using the Brainpulse™

A Randomized Controlled Trial Investigating if Antibiotic Use in the First 48 Hours of Life Adversely Impacts the Preterm Infant Microbiome

A Randomized Controlled Trial of a Conservative Fluid Balance Strategy for Patients With Sepsis and Cardiopulmonary Dysfunction (BALANCE Study)

Pharmacokinetics and Safety of Piperacillin-tazobactam in Neonates

ACCESS: A Controlled Comparison of Eritoran Tetrasodium and Placebo in Patients With Severe Sepsis

Concept Elicitation and Patient Experience Mapping in SA-AKI

Does Serum Procalcitonin Levels Predict Sepsis in Patients Undergoing Cytoreductive Surgery

Endourology Disease Group Excellence (EDGE) Consortium: Antibiotics (Abx) for Percutaneous Nephrolithotomy (PCNL) Part 2

Early Versus Late Adjunctive Vasopressin in Septic Shock

Phase 3 Study of Reltecimod vs Placebo in Patients With Sepsis-associated Acute Kidney Injury

A Safety and Efficacy Study of Intravenous E5564 in Patients With Severe Sepsis

Smart Discharges for Older Children

The CRISIS Prevention Study

Study of the Relationship Between Feeding and Late Onset Sepsis and/or Necrotizing Enterocolitis in Low Birth Weight Infants

Sepsis Post Market Observational Study and Potential Reduction of Time to Antibiotics - Washington University

Clinical Trial of the Optimal Endpoint of Early Sepsis Resuscitation

Gene Expression Objective Definition of Early Sepsis In Children