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ClinicalTrials.gov public records Last synced Nov 14, 2026, 7:18 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 481–504 of 517 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sepsis Clear all

Conditions: Medical Knowledge, Clinical Performance
Interventions: Debriefing of high-fidelity sepsis simulation scenarios, Placebo: Debriefing of high-fidelity non-sepsis simulation scenarios; Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 20 Years to 60 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: New York, New York

Conditions: Sepsis, Adult Disease, Emergency Department, Severe Sepsis
Interventions: CBC-DIFF Monocyte Volume Width Distribution (MDW); Diagnostic Test
Lead sponsor: Beckman Coulter, Inc.; Industry
Eligibility: 18 Years to 89 Years
Enrollment: 1,700 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Temple, Texas

Conditions: Shock, Sepsis, Hypotension, Critical Illness
Interventions: Tranexamic Acid, Control Intervention (Carrier fluid only); Drug
Lead sponsor: San Diego Veterans Healthcare System; Federal
Eligibility: 18 Years and older
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: San Diego, California

Conditions: Sepsis
Interventions: Suspected Sepsis Group - Diagnostic Measurements, Control Group - Diagnostic Measurements; Diagnostic Test
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Sepsis, SIRS
Interventions: Nanomix eLab® System molecular diagnostic test (non-interventional); Other
Lead sponsor: Nanomix; Industry
Eligibility: 18 Years and older
Enrollment: 184 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Streptococcus Pneumoniae
Interventions: pneumoniae bacteremia therapy; Drug
Lead sponsor: Methodist Health System; Other
Eligibility: 18 Years to 75 Years
Enrollment: 200 participants
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Lumbar Puncture
Interventions: ultrasound contrast; Device
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 1 Day to 12 Months
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Infection, Hypervolemia, Hypovolemia, Septic Shock, Acute Heart Failure, Congestive Heart Failure
Interventions: Peripheral Intravenous Analysis (PIVA), Non-invasive fluid response measure, Passive leg raise (PLR); Procedure · Diagnostic Test
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2021
U.S. locations: 3
States / cities: Boston, Massachusetts • Worcester, Massachusetts • Seattle, Washington

Conditions: Acute Lymphoblastic Leukemia
Interventions: Wearable Sensors; Other
Lead sponsor: St. Jude Children's Research Hospital; Other
Eligibility: 5 Years to 25 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Systemic Inflammatory Response Syndrome (SIRS), Sepsis
Interventions: Not listed
Lead sponsor: Seattle Children's Hospital; Other
Eligibility: 38 Weeks to 18 Years
Enrollment: 104 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Severe Sepsis, Coagulopathy
Interventions: ART-123, Placebo; Drug
Lead sponsor: Asahi Kasei Pharma America Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 816 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2019
U.S. locations: 22
States / cities: Mobile, Alabama • Phoenix, Arizona • Atlanta, Georgia + 17 more

Conditions: Severe Sepsis, Respiratory Failure
Interventions: Not listed
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Healthy
Interventions: LabClasp; Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Sepsis
Interventions: Not listed
Lead sponsor: Northwell Health; Other
Eligibility: 18 Years and older
Enrollment: 134 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Manhasset, New York

Conditions: Sepsis
Interventions: Additional physical therapy; Procedure
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Healthy
Interventions: CVC Train the Trainer; Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 226 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Severe Sepsis
Interventions: Severe sepsis early warning best practice alert, Standard care; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 1,149 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Stanford, California

Conditions: Sepsis
Interventions: Vital Signs at 2 Hours, Confusion Assessment method for the ICU (CAM-ICU); Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 110 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: New York, New York

Conditions: Sepsis, Infection
Interventions: Cytovale IntellipSep test; Diagnostic Test
Lead sponsor: Cytovale, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 599 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 4
States / cities: Baton Rouge, Louisiana • Columbia, Missouri • Winston-Salem, North Carolina + 1 more

Conditions: Severe Sepsis, Septic Shock
Interventions: Pioglitazone hydrochloride; Drug
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: Not listed
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2017
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Sepsis, Severe Sepsis, Septic Shock, Multi-organ Failure
Interventions: Not listed
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Severe Sepsis, Septic Shock
Interventions: Esophageal Doppler monitoring - CardioQ, Deltex Inc, Central line with CVP and continuous ScvO2 monitoring; Device
Lead sponsor: Loma Linda University; Other
Eligibility: 18 Years and older
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 4
States / cities: Loma Linda, California • Worcester, Massachusetts • Detroit, Michigan

Conditions: Healthy Volunteer Safety Study
Interventions: AB103, Placebo; Drug
Lead sponsor: Atox Bio Ltd; Industry
Eligibility: 18 Years to 40 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Severe Sepsis, Septic Shock
Interventions: BMS-936559, Placebo; Biological · Other
Lead sponsor: Bristol-Myers Squibb; Industry
Eligibility: 18 Years and older
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 13
States / cities: Sacramento, California • Denver, Colorado • Gainesville, Florida + 10 more

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Utility of High-Fidelity Simulation In the Education and Assessment of Residents in the Recognition and Management of the Sepsis Syndrome

Sepsis Post Market Observational Study and Potential Reduction of Time to Antibiotics - Baylor S&W

Single Dose Enteral Tranexamic Acid in Critically Ill Patients

Mitochondrial Dysfunction Contributes to Sepsis Induced Cardiac Dysfunction

Performance Evaluation of the Nanomix eLab® CRP, PCT, and LAC Assays With the Nanomix eLab System

Short Versus Long Duration of Therapy for Streptococcus Pneumoniae Bloodstream Infections

Hemorrhage Elimination During Lumbar Puncture Using Ultrasound Measurements (HELPUS)

Observational Study to Evaluate Peripheral IntraVenous Analysis (PIVA) in Euvolemic, Hypovolemic, and Hypervolemic Emergency Department Patients

Continuous Ambulatory Monitoring to Predict Elevated Risk of Infection in Children With Lymphoblastic Leukemia Undergoing Induction Chemotherapy (CAMPER-ALL)

Genotypes and Phenotypes in Pediatric SIRS and Sepsis

Phase 3 Safety and Efficacy Study of ART-123 in Subjects With Severe Sepsis and Coagulopathy

Muscle Atrophy in Patients With Severe Sepsis

Estimating Blood [Lactate] Non-Invasively

Point of Care Ultrasound to Predict Intensive Care Unit Admission of Patients Presenting With Sepsis to the Emergency Department

Sepsis Trial of Early Physical Therapy Outside the ICU

Central Venous Catheter Insertion Train the Trainer

Study of an Electronic Health Record-embedded Severe Sepsis Early Warning Alert

Sepsis Pre-Alert Monitoring Intervention: Study to Investigate Targeted Enhanced Monitoring for Sepsis

CV-SQuISH-ED: Clinical Validation Study

Pharmacokinetic and Biomarker Study of Pioglitazone in Adolescents With Severe Sepsis and Septic Shock

Alveolar Dead Space as Predictor of Organ Failure in Severe Sepsis

Minimally-Invasive Cardiovascular Hemodynamic Optimization (MiCHO) Versus Early Goal-Directed Therapy (EGDT) in the Management of Septic Shock

AB103 Peptide Antagonist in Healthy Volunteers

Safety, Pharmacokinetics and Pharmacodynamics of BMS-936559 in Severe Sepsis