Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 12, 2026, 9:05 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 517 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sepsis Clear all

Conditions: Sepsis
Interventions: Fluid Resuscitation, Standard of Care; Other
Lead sponsor: Cheetah Medical Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 12
States / cities: Birmingham, Alabama • Sacramento, California • Denver, Colorado + 7 more

Conditions: Staphylococcus Aureus Bacteremia, Staphylococcus Aureus Endocarditis
Interventions: CF-301, Placebo; Biological · Drug
Lead sponsor: ContraFect; Industry
Eligibility: 18 Years and older
Enrollment: 121 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 31
States / cities: Birmingham, Alabama • Sacramento, California • Sylmar, California + 25 more

Conditions: Pneumonia, Sepsis
Interventions: Recombinant Chimeric Monoclonal Antibody; Drug
Lead sponsor: ICOS Corporation; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2002
U.S. locations: 1
States / cities: Bothell, Washington

Conditions: Acute Kidney Injury, Peritonitis, Necrotizing Soft Tissue Infection
Interventions: Reltecimod 0.5 mg/kg, Placebo; Drug
Lead sponsor: Atox Bio Ltd; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 58 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 40
States / cities: Phoenix, Arizona • Tucson, Arizona • Little Rock, Arkansas + 33 more

Conditions: Sepsis, Septicemia, Sepsis Syndrome, Shock, Septic, Community Acquired Pneumonia
Interventions: Not listed
Lead sponsor: National Center for Genome Resources; Other
Eligibility: 6 Years and older
Enrollment: 1,200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2010
U.S. locations: 3
States / cities: Detroit, Michigan • Durham, North Carolina

Conditions: Glucose, Metabolism, Isotope Labeling, Immune System and Related Disorders, Critical Illness, Intensive Care Unit (ICU), Sepsis
Interventions: 13C6-Glucose; Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Sepsis, Septic Shock
Interventions: Vitamin C, Vitamin B1; Drug
Lead sponsor: Trinity Health Of New England; Other
Eligibility: 18 Years to 90 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Hartford, Connecticut

Conditions: Kidney Failure, Chronic, Catheter-Related Infections
Interventions: Neutrolin, Heparin; Drug
Lead sponsor: CorMedix Therapeutics; Industry
Eligibility: 18 Years and older
Enrollment: 806 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 5
States / cities: Riverside, California • San Dimas, California • Miami Gardens, Florida + 2 more

Conditions: Sepsis
Interventions: Telemedicine; Other
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years and older
Enrollment: 1,191 participants
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Acute Kidney Injury
Interventions: Pediatric Quality of Life (Peds QL) Survey; Other
Lead sponsor: University of Florida; Other
Eligibility: 2 Years to 36 Years
Enrollment: 73 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2024
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Acute Respiratory Infection
Interventions: HostDx Fever Test, HostDx Sepsis Test; Diagnostic Test
Lead sponsor: Inflammatix; Industry
Eligibility: 1 Year and older
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Burlingame, California

Conditions: Sepsis
Interventions: Implementation and evaluation of a sepsis sub-phenotyping algorithm; Other
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 1,916 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 4
States / cities: Atlanta, Georgia • Johns Creek, Georgia

Conditions: Neonatal Early-onset Sepsis, Neonatal Late-onset Sepsis
Interventions: Intervention is to stop antibiotics at 24h .; Other
Lead sponsor: Yale University; Other
Eligibility: 1 Hour to 5 Months
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Hematologic Malignancy, Leukemia, Acute, Neutropenia, Bloodstream Infection
Interventions: No intervention.; Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 168 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 6
States / cities: San Francisco, California • Nutley, New Jersey • New York, New York + 3 more

Conditions: Septic Shock, Vasodilatory Shock
Interventions: Angiotensin II; Drug
Lead sponsor: University of New Mexico; Other
Eligibility: 18 Years and older
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Severe Trauma
Interventions: Not listed
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 213 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2013
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Sepsis, Acute Kidney Injury Due to Sepsis, Acute Kidney Injury (Nontraumatic)
Interventions: Not listed
Lead sponsor: Northwell Health; Other
Eligibility: 1 Day to 18 Years
Enrollment: 74 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: New Hyde Park, New York

Conditions: Sepsis, Systemic Inflammatory Response Syndrome, Infection Mixed, Infection, Bacterial, Infection, Fungal, Infection, Coronavirus, Antibiotic Resistance Genes, Human Genome Analysis
Interventions: Gene Z or other rapid diagnostic techniques developed in our lab (as of 2018 not using Gene Z - now using In-Dx along with other developed techniquesregularly); Device
Lead sponsor: Michigan State University; Other
Eligibility: 18 Years and older
Enrollment: 2,500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2032
U.S. locations: 2
States / cities: Lansing, Michigan

Conditions: Sepsis
Interventions: Near-real time automated feedback on SEP-1 performance; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: San Diego, California

Conditions: Candidemia, Mycoses, Fungal Infection, Fungemia, Invasive Candidiasis, Pneumocystis, Mold Infection, Invasive Fungal Disease, Prophylaxis of Invasive Fungal Infections, Aspergillus
Interventions: Rezafungin for Injection, Posaconazole, Fluconazole, Trimethoprim-sulfamethoxazole (TMP/SMX), Intravenous Placebo, Oral Placebo; Drug
Lead sponsor: Mundipharma Research Limited; Industry
Eligibility: 18 Years and older
Enrollment: 602 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 18
States / cities: Birmingham, Alabama • Los Angeles, California • Stanford, California + 13 more

Conditions: Sepsis, Severe, Septic Shock
Interventions: Ascorbic Acid, Thiamine, Hydrocortisone, Sodium Chloride 0.9%; Drug
Lead sponsor: Community Medical Center, Toms River, NJ; Other
Eligibility: 18 Years and older
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 2
States / cities: Lakewood, New Jersey • Toms River, New Jersey

Conditions: Congenital Heart Disease, Sepsis, Infection
Interventions: Not listed
Lead sponsor: Emory University; Other
Eligibility: Up to 5 Years
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Sepsis
Interventions: Additional physical therapy; Procedure
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Vascular Access Complication, Central Line Complication, Central Line-Associated Infection, Superficial Vein Thrombosis, Deep Vein Thrombosis
Interventions: Midline catheter; Device
Lead sponsor: Corewell Health East; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Royal Oak, Michigan

Search by objective public record fields.

Cardiac Output Monitoring Managing Intravenous Therapy (COMMIT) to Treat Emergency Department Severe Sepsis

Safety, Efficacy and Pharmacokinetics of CF-301 vs. Placebo in Addition to Antibacterial Therapy for Treatment of S. Aureus Bacteremia

A Safety and Efficacy Study of Hospitalized Patients With Community-Acquired Pneumonia and Sepsis

Phase 3 Study of Reltecimod vs Placebo in Patients With Sepsis-associated Acute Kidney Injury

Observational Study of Sepsis and Pneumonia to Develop Diagnostic Tests

Tracing Of Real-time glu13Cose Metabolism in Human Immune Cells - Intensive Care Unit

Vitamin C & Thiamine to Treat Sepsis and Septic Shock

Study Assessing Safety & Effectiveness of a Catheter Lock Solution in Dialysis Patients to Prevent Bloodstream Infection

TELEmedicine as an Intervention for Sepsis in Emergency Departments

Long Term Cognitive Impact of Pediatric Acute Renal Injury

Collection of Clinical Specimens From Volunteers for Assay Development

Novel Sepsis Sub-phenotypes Based on Trajectories of Vital Signs

A Pilot Randomized Controlled Trial for Antibiotic Exposure in Neonatal Sepsis Using Neutrophil CD64

Screening for Colonization With Resistant Enterobacterales in Neutropenic Patients With Hematologic Malignancies

Serum Biomarkers to Predict Response to Angiotensin II in Septic Shock

Immune-cell Membrane Trafficking

Renin Angiotensin Aldosterone System In Septic Kids

Clinical Microbial Species & Antibiotic Resistance ID in ED Patients Presenting With Infection - is Rapid ID Possible & Accurate?

Using AI to Improve Sepsis Quality of Care in the Emergency Department

Study of Rezafungin Compared to Standard Antimicrobial Regimen for Prevention of Invasive Fungal Diseases in Adults Undergoing Allogeneic Blood and Marrow Transplantation

Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in Sepsis.

Pro-Calcitonin Levels Following Pediatric Cardiac Surgery

Sepsis Trial of Early Physical Therapy Outside the ICU

Novel Strategy to Encourage Early Removal of Central Venous Catheters