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ClinicalTrials.gov public records Last synced Nov 12, 2026, 9:17 AM EST

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Showing 73–96 of 517 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sepsis Clear all

Conditions: Sepsis
Interventions: Muscle stimulation with Niveus medical stimulator, measurement of maximal isometric twitch strength, Muscle Biopsy, Muscle Biopsy Medication: Lidocaine, Muscle Biopsy Medication: Versed, Muscle Biopsy Medication: Fentanyl, Blood and Urine Sampling, ineffective muscle stimulation; Device · Procedure · Drug + 1 more
Lead sponsor: University of Florida; Other
Eligibility: 18 Years and older
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Sepsis, Septic Shock, Sepsis-Associated Immune Dysregulation
Interventions: Not listed
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: 18 Years to 100 Years
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2037
U.S. locations: 1
States / cities: Falls Church, Virginia

Conditions: Signs and Symptoms, Respiratory
Interventions: Not listed
Lead sponsor: Baylor Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 87 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Sepsis, Critical Illness, Respiratory Failure, Nutrition Disorders, Calorie Deficiency, Diaphragm Injury, Quadriceps Muscle Atrophy
Interventions: Caloric delivery will target results of IC measurement.; Other
Lead sponsor: Baylor Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: SIRS, Sepsis
Interventions: Not listed
Lead sponsor: Mochida Pharmaceutical Company, Ltd.; Industry
Eligibility: 21 Years and older
Enrollment: 226 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 2
States / cities: Boston, Massachusetts

Conditions: Acute Respiratory Failure
Interventions: IV Ganciclovir, Normal saline; Drug
Lead sponsor: Fred Hutchinson Cancer Center; Other
Eligibility: 18 Years to 85 Years
Enrollment: 205 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 20
States / cities: Denver, Colorado • Baltimore, Maryland • Boston, Massachusetts + 16 more

Conditions: Hypovitaminosis D
Interventions: Cholecalciferol, Placebo; Dietary Supplement
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Acinetobacter Infections
Interventions: Not listed
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2017
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Sepsis
Interventions: Vital Signs at 2 Hours, Confusion Assessment method for the ICU (CAM-ICU); Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 110 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: New York, New York

Conditions: Sepsis, Electronic Health Records, Clinical Decision Support Systems
Interventions: Nurse SIRS alert, Prescribing clinician SIRS alert; Other
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 25,668 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: New York, New York

Conditions: Septic Shock
Interventions: Seraph-100 + State of the Art Care, State of the Art Care; Device
Lead sponsor: ExThera Medical Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 9
States / cities: Washington D.C., District of Columbia • Brunswick, Georgia • Ann Arbor, Michigan + 5 more

Conditions: Sepsis
Interventions: Inhaled nitric oxide, Sham inhaled nitric oxide; Drug · Other
Lead sponsor: National Institute of General Medical Sciences (NIGMS); NIH
Eligibility: 14 Years and older
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Camden, New Jersey

Conditions: Antibiotic Stewardship
Interventions: Opt-Out Protocol; Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 762 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 10
States / cities: Atlanta, Georgia • Fayetteville, Georgia • Newnan, Georgia + 6 more

Conditions: Sepsis, Deterioration, Clinical, Critical Illness, Early Warning Score
Interventions: Algorithm-triggered sepsis alert with structured critical care team activation; Other
Lead sponsor: Patricks Lyons; Other
Eligibility: 18 Years and older
Enrollment: 3,700 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Catheter-associated Bloodstream Infections (CLABSI)
Interventions: Sample collection; Other
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 1 Day to 3 Weeks
Enrollment: 144 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Sepsis, Systemic Inflammatory Response Syndrome (SIRS)
Interventions: Not listed
Lead sponsor: Immunexpress; Industry
Eligibility: 18 Years to 89 Years
Enrollment: 379 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 6
States / cities: Atlanta, Georgia • Chicago, Illinois • Maywood, Illinois + 3 more

Conditions: Sepsis
Interventions: Not listed
Lead sponsor: Northwell Health; Other
Eligibility: 18 Years and older
Enrollment: 134 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Manhasset, New York

Conditions: Severe Sepsis, Critical Illness
Interventions: Not listed
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years and older
Enrollment: 250 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2019
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Sepsis, Respiratory Distress Syndrome, Respiratory Distress Syndrome, Adult
Interventions: vasoactive intestinal peptide; Drug
Lead sponsor: Stony Brook University; Other
Eligibility: 18 Years and older
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 1998
U.S. locations: 2
States / cities: Northport, New York • Stony Brook, New York

Conditions: Microbial Colonization, Extreme Prematurity, Early-Onset Neonatal Sepsis, Late-Onset Neonatal Sepsis, Necrotizing Enterocolitis of Newborn, Death; Neonatal
Interventions: Ampicillin, Gentamycin, Normal saline; Drug
Lead sponsor: Michael Morowitz; Other
Eligibility: Up to 4 Hours
Enrollment: 359 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 14
States / cities: Mobile, Alabama • San Diego, California • New Haven, Connecticut + 10 more

Conditions: Catheter-related Infections
Interventions: Mino-Lok, Antibiotic lock; Drug
Lead sponsor: Leonard-Meron Biosciences, Inc.; Industry
Eligibility: 12 Years and older
Enrollment: 144 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 19
States / cities: Washington D.C., District of Columbia • Gainesville, Florida • Hines, Illinois + 16 more

Conditions: Sepsis, Adult Disease, Emergency Department, Severe Sepsis
Interventions: CBC-DIFF Monocyte Volume Width Distribution (MDW); Diagnostic Test
Lead sponsor: Beckman Coulter, Inc.; Industry
Eligibility: 18 Years to 89 Years
Enrollment: 1,700 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Temple, Texas

Conditions: Sepsis
Interventions: Suspected Sepsis Group - Diagnostic Measurements, Control Group - Diagnostic Measurements; Diagnostic Test
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Cancer, Leukemia, Stem Cell Transplantation
Interventions: C-Reactive Protein levels; Behavioral
Lead sponsor: Ann & Robert H Lurie Children's Hospital of Chicago; Other
Eligibility: 6 Months to 20 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2008
U.S. locations: 1
States / cities: Chicago, Illinois

Search by objective public record fields.

Project 4B: Lower Extremity Strength Training in ICU Patients

Immune Dysregulation During Sepsis: A Natural History Cohort

Improved Patient Safety Through Continuous Bi-channel RR and SpO2 Monitoring With Masimo Patient SafetyNet

Indirect Calorimetry Usage and Effect in Ventilator-free Days and Muscle Thickness in Septic Ventilated Patients

Utility of Presepsin in Distinguishing Between Sepsis and SIRS

Ganciclovir to Prevent Reactivation of Cytomegalovirus in Patients With Acute Respiratory Failure and Sepsis

Cholecalciferol Supplementation for Sepsis in the ICU

Multinational Study of Acinetobacter Bloodstream Infection: Clinical Outcomes and Global Epidemiology-PITT Protocol

Sepsis Pre-Alert Monitoring Intervention: Study to Investigate Targeted Enhanced Monitoring for Sepsis

Sepsis Electronic Prompting for Timely Intervention and Care for Emergency Department Patients

Blood Purification for the Treatment of Pathogen Associated Shock

Randomized Trial of Inhaled Nitric Oxide to Augment Tissue Perfusion in Sepsis

The DETOURS Trial: De-escalating Empiric Treatment: Opting Out of Rx for Selected Patients With Suspected Sepsis - Opt-Out Protocol Trial

Hospital-Onset Sepsis Systematic Detection and Structured Interventions

Catheter Biofilm Microbiome in Infected Neonatal Catheters.

VENUS: Septic Gene Expression Using SeptiCyte

Point of Care Ultrasound to Predict Intensive Care Unit Admission of Patients Presenting With Sepsis to the Emergency Department

Ultrasound Measurement of Reactive Hyperemia in Critical Care

Phase I Study of Vasoactive Intestinal Peptide in Patients With Acute Respiratory Distress Syndrome and Sepsis

NICU Antibiotics and Outcomes Trial

Mino-Lok Therapy (MLT) for the Treatment of CRBSI/CLABSI

Sepsis Post Market Observational Study and Potential Reduction of Time to Antibiotics - Baylor S&W

Mitochondrial Dysfunction Contributes to Sepsis Induced Cardiac Dysfunction

C-Reactive Protein as a Predictor of Stem Cell Transplant Complications