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ClinicalTrials.gov public records Last synced Nov 12, 2026, 9:52 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 169–192 of 517 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sepsis Clear all

Conditions: Acute Kidney Injury, Septic Shock, Resuscitations
Interventions: Abdominal Perfusion Pressure (APP), Mean Arterial Pressure (MAP); Device
Lead sponsor: Potrero Medical; Industry
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 3
States / cities: Little Rock, Arkansas • Atlanta, Georgia

Conditions: Adrenal Insufficiency
Interventions: Not listed
Lead sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); NIH
Eligibility: 15 Years to 65 Years
Enrollment: 225 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2004
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Bloodstream Infection, Sepsis, Septic Shock
Interventions: InfectID-BSI (Bloodstream Infection) qPCR Assay; Diagnostic Test
Lead sponsor: Microbio Co Ltd; Industry
Eligibility: Not listed
Enrollment: 1,500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 5
States / cities: Indianapolis, Indiana • Baltimore, Maryland • Albuquerque, New Mexico + 2 more

Conditions: Sepsis, Severe Sepsis, Systemic Inflammatory Response Syndrome, Sepsis Syndrome
Interventions: Not listed
Lead sponsor: Inverness Medical Innovations; Industry
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007
U.S. locations: 3
States / cities: Boston, Massachusetts • Cleveland, Ohio • Philadelphia, Pennsylvania

Conditions: Sepsis, Altered Mental Status, Sepsis-Associated Delirium, Sepsis Associated Encephalopathy, Delirium, Sepsis Associated
Interventions: Blood draws; Procedure
Lead sponsor: University of Florida; Other
Eligibility: 18 Years and older
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2026
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Bloodstream Infection
Interventions: Not listed
Lead sponsor: St. Jude Children's Research Hospital; Other
Eligibility: Up to 24 Years
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2027
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Sepsis-associated Acute Kidney Injury
Interventions: Not listed
Lead sponsor: Novartis Pharmaceuticals; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: East Hanover, New Jersey

Conditions: Sepsis
Interventions: SCTP; Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 3,269 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Sepsis, Septic Shock
Interventions: Not listed
Lead sponsor: Bluejay Diagnostics, Inc.; Industry
Eligibility: 22 Years and older
Enrollment: 143 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 7
States / cities: Boston, Massachusetts • St Louis, Missouri • Brooklyn, New York + 4 more

Conditions: Septic Shock
Interventions: Angiotensin II, Norepinephrine; Drug
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 78 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 2
States / cities: Boston, Massachusetts • Winston-Salem, North Carolina

Conditions: Cholangitis, Bacteremia
Interventions: Cholangioscopy; Procedure
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 18 Years to 80 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Premature Birth of Newborn, Enterocolitis, Necrotizing
Interventions: Ampicillin, Gentamicins, Placebo; Drug
Lead sponsor: University of Chicago; Other
Eligibility: Up to 6 Hours
Enrollment: 27 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Necrotizing Enterocolitis, Sepsis
Interventions: Fortified Pasteurized Donor Human Milk supplement, Preterm Formula supplement; Behavioral
Lead sponsor: National Center for Research Resources (NCRR); NIH
Eligibility: 0 Years to 96 Hours
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 1997
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Sepsis, Severe Sepsis, Systemic Inflammatory Response Syndrome
Interventions: ED Sepsis Tracking Sheet; Procedure
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 194 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Lebanon, New Hampshire

Conditions: Dental Caries in Children
Interventions: Modified CariesCare International management; Procedure
Lead sponsor: Universidad El Bosque, Bogotá; Other
Eligibility: 3 Years to 8 Years
Enrollment: 409 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 2
States / cities: Indianapolis, Indiana • Boston, Massachusetts

Conditions: Bloodstream Infections, Short Bowel Syndrome, Development, Nutrition, Biological Markers
Interventions: Glutamine, L-alanine; Drug · Dietary Supplement
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 6 Weeks to 12 Months
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2015
U.S. locations: 2
States / cities: Ann Arbor, Michigan • Cincinnati, Ohio

Conditions: Sepsis
Interventions: LifeFlow Rapid infuser, Push Pull; Device
Lead sponsor: Phoenix Children's Hospital; Other
Eligibility: 1 Year to 19 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Severe Sepsis or Septic Shock
Interventions: Calcitriol, Placebo; Drug
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 67 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Sepsis
Interventions: Bilateral phrenic nerve stimulation and measurement of transdiaphragmatic pressure, Midazolam, Volitional Measurement of Maximal Inspiratory Pressure (MIP), Inspiratory Muscle Strength Training (IMST), SHAM Inspiratory Muscle Strength Training (IMST), Diaphragm thickness measurement, Blood and Urine samples; Procedure · Drug · Device + 1 more
Lead sponsor: University of Florida; Other
Eligibility: 18 Years and older
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Burns, Sepsis
Interventions: PCR test; Other
Lead sponsor: American Burn Association; Other
Eligibility: 18 Years to 90 Years
Enrollment: 218 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2019
U.S. locations: 4
States / cities: Sacramento, California • Miami, Florida • Cincinnati, Ohio + 1 more

Conditions: Sepsis
Interventions: Not listed
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 84 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2008
U.S. locations: 2
States / cities: Minneapolis, Minnesota • Rochester, Minnesota

Conditions: Severe Sepsis
Interventions: Not listed
Lead sponsor: Bluejay Diagnostics, Inc.; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Acton, Texas

Conditions: Infants in Neonatal Intensive Care Units
Interventions: Education Plus (E+), Clinical Decision Support, Prescriber Audit and Feedback; Other
Lead sponsor: Columbia University; Other
Eligibility: Not listed
Enrollment: 6,184 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 4
States / cities: Wilmington, Delaware • New York, New York • Philadelphia, Pennsylvania

Conditions: Kidney Stone, Kidney Calculi, Urinary Tract Obstruction, Infection, Sepsis
Interventions: Initial clinical and laboratory evaluation; Other
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 477 participants
Timeline: 2019 – 2020
U.S. locations: 2
States / cities: Dallas, Texas

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Targeting Abdominal Perfusion Pressure in Septic Shock

Adrenal Function in Critical Illness

Clinical Performance Study of Microbio InfectID-BSI for Detection of Bacteria and Yeast With Patient Blood Samples

The Utility of Ischemia Modified Albumin (IMA) in Sepsis

Sepsis Associated Encephalopathy (SAE) Biomarkers

Next Generation Pathogen Sequencing for Prediction of Adverse Events

Concept Elicitation and Patient Experience Mapping in SA-AKI

Effect of Automated Real-time Feedback on Early Sepsis Care

Multicenter Symphony IL-6 Monitoring Sepsis ICU Study

Mechanistic Assessment of Norepinephrine Therapy vs. Angiotensin-II in Septic Shock

Factors Associated With Increased Risk of Bacteremia and Cholangitis in ERCP With Cholangioscopy

A Randomized Controlled Trial Investigating if Antibiotic Use in the First 48 Hours of Life Adversely Impacts the Preterm Infant Microbiome

Study of the Relationship Between Feeding and Late Onset Sepsis and/or Necrotizing Enterocolitis in Low Birth Weight Infants

ED Tracking Sheet Implementation

Pandemic-adapted Caries Care Multicentre Single-group Interventional Study

Enteral Glutamine in Reducing Bloodstream Infections in Short Bowel Syndrome Infants

LifeFlow Sepsis Study

Randomized Controlled Trial of Calcitriol vs. Placebo Among Critically-ill Patients With Sepsis

Project 4A: Inspiratory Muscle Training and Diaphragm Strength

Rapid Detection of Staphylococcus Aureus in Burn Patients

A Simple Clinical Tool to Help Assess Patient Volume (Fluid) Status

Symphony IL-6 Cutoff Validation Study for Patients at Risk of Severe Sepsis

Improving Antimicrobial Prescribing Practices in the Neonatal ICU

Evaluation of Infection in Obstructing Urolithiasis