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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Sexual Risk Reduction Intervention Clear all
Completed Phase 2 Interventional Results available

Interventions for HIV Negative Men and Women Who Have High-risk Suspected Exposure to HIV

NCT00949234
View directory record Official record
Conditions
HIV Prevention, HIV Infections
Interventions
tenofovir + emtricitabine, lopinavir/ritonavir
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
267 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 17, 2017 · Synced Sep 24, 2026, 4:29 AM EDT
Completed Not applicable Interventional

Distress Tolerance and HIV Prevention With XR-NTX Initiation in Opioid Dependence

NCT02602795
View directory record Official record
Conditions
Opiate Dependence, Sexually Transmitted Diseases, HIV
Interventions
Acceptance and Commitment Therapy, Information Motivation Behavioral Model
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 28, 2018 · Synced Sep 24, 2026, 4:29 AM EDT
Completed Not applicable Interventional

Partner-Specific HIV Risk Reduction Intervention for Drug-Using Adolescents

NCT00831883
View directory record Official record
Conditions
Sexually Transmitted Diseases, Substance-Related Disorders
Interventions
Partner-Specific IMB-based HIV risk reduction intervention, Healthy Lifestyle
Behavioral
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
15 Years to 18 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 4, 2012 · Synced Sep 24, 2026, 4:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Multi-Component Alcohol and Sex Risk Intervention for College Students

NCT05180539
View directory record Official record
Conditions
College Drinking
Interventions
SPLASH Intervention Condition, Control Condition
Behavioral
Lead sponsor
Lehigh University
Other
Eligibility
18 Years to 24 Years
Enrollment
274 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Bethlehem, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced Sep 24, 2026, 4:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Parent-Based Intervention to Reduce Sexual Risk Behavior in Adolescents

NCT00461487
View directory record Official record
Conditions
Behavior and Behavior Mechanisms
Interventions
Active control on hygiene and nutrition, Families Talking Together
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
11 Years to 14 Years
Enrollment
530 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 10, 2013 · Synced Sep 24, 2026, 4:29 AM EDT
Completed Not applicable Interventional Results available

Understanding and Reducing HIV Risk Behavior and Substance Use Among Self-identified Bisexual Adolescent Men

NCT03409328
View directory record Official record
Conditions
HIV/AIDS, Substance Use, Bisexuality
Interventions
HIV and substance use prevention
Behavioral
Lead sponsor
Rosalind Franklin University of Medicine and Science
Other
Eligibility
14 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
North Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 21, 2024 · Synced Sep 24, 2026, 4:29 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

A Randomized Controlled Trial of the Bruthas Project

NCT01270230
View directory record Official record
Conditions
HIV Infection
Interventions
Bruthas Project, Standard HIV Testing and Counseling
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
396 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 26, 2016 · Synced Sep 24, 2026, 4:29 AM EDT
Completed Phase 2Phase 3 Interventional

A Bundled Rapid HIV/HCV Testing Intervention to Increase Receipt of Test Results

NCT02355080
View directory record Official record
Conditions
Substance-related Disorders
Interventions
On-site bundled rapid HIV/HCV testing, Standard of care (SOC)
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 22, 2018 · Synced Sep 24, 2026, 4:29 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

PAIRS: Friend-Based AISA Intervention

NCT07433270
View directory record Official record
Conditions
Sexual Violence, College Drinking, Behavioral Changes
Interventions
Friend-Based Motivational Interview, Treatment as usual (TAU)
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years to 24 Years · Female only
Enrollment
560 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 24, 2026, 4:29 AM EDT
Completed Not applicable Interventional

Contextualizing & Responding to HIV Risk Behaviors

NCT03300908
View directory record Official record
Conditions
Human Immunodeficiency Virus
Interventions
Project ADHERE, MACE
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 3, 2017 · Synced Sep 24, 2026, 4:29 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

MyPEEPS LITE Trial

NCT06741631
View directory record Official record
Conditions
HIV/AIDS
Interventions
MyPEEPS Mobile
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
16 Years to 29 Years · Male only
Enrollment
3,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
2
States / cities
Chicago, Illinois • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 24, 2026, 4:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility Testing a Meditation App for Youth in the Legal System

NCT05146167
View directory record Official record
Conditions
Behavioral Health
Interventions
Bodhi AIM (intervention group), HIB (control group)
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
13 Years to 18 Years
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Sep 24, 2026, 4:29 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Project Power: An HIV Risk Reduction Intervention for Black Men Who Have Sex With Men and Women (BMSM/W)

NCT01376895
View directory record Official record
Conditions
Unsafe Sex, Risk Reduction
Interventions
PROJECT POWER, Power Health
Behavioral
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 60 Years · Male only
Enrollment
211 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 10, 2014 · Synced Sep 24, 2026, 4:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reduction of Drug Use and HIV Risk Among Out-of-Treatment Methamphetamine Users

NCT01161485
View directory record Official record
Conditions
HIV Infections
Interventions
HIV Testing and Counseling, Contingency Management, Strengths-based case management
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
502 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 19, 2017 · Synced Sep 24, 2026, 4:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

MyLife MyStyle Evaluation Project

NCT01640392
View directory record Official record
Conditions
Unsafe Sex
Interventions
MyLife MyStyle group-level intervention
Behavioral
Lead sponsor
Los Angeles County Department of Public Health
Government
Eligibility
18 Years to 29 Years · Male only
Enrollment
528 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2019 · Synced Sep 24, 2026, 4:29 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Transmasculine One-on-One and Group Empowerment for Targeted HIV Reduction

NCT06182280
View directory record Official record
Conditions
HIV Infections, Adherence, Medication
Interventions
PrEP4T, LS4TM
Behavioral
Lead sponsor
Fenway Community Health
Other
Eligibility
18 Years and older · Male only
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Sep 24, 2026, 4:29 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Can the IDEA3 Intervention Prevent Intimate Partner Violence?: A Substudy to the IDEA3 Randomized Controlled Trial

NCT07218159
View directory record Official record
Conditions
Intimate Partner Violence (IPV)
Interventions
IDEA3 Sexual Assault Resistance Intervention, Consent workshop
Behavioral
Lead sponsor
University of Maryland, College Park
Other
Eligibility
17 Years to 26 Years
Enrollment
289 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
3
States / cities
Orlando, Florida • College Park, Maryland • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Sep 24, 2026, 4:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adaptation and Implementation of Project Encuentro in the U.S.-Mexico Border

NCT03293875
View directory record Official record
Conditions
HIV
Interventions
Community Events, Social Network HIV Testing, Peer Network Intervention
Behavioral
Lead sponsor
City University of New York
Other
Eligibility
18 Years and older
Enrollment
840 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Sep 25, 2025 · Synced Sep 24, 2026, 4:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

HIV Rapid Testing & Counseling in Sexually Transmitted Disease (STD) Clinics in the U.S.

NCT01154296
View directory record Official record
Conditions
HIV/AIDS, Sexually Transmitted Infections
Interventions
RESPECT-2 Counseling
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
5,012 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
9
States / cities
Los Angeles, California • San Francisco, California • Washington D.C., District of Columbia + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2014 · Synced Sep 24, 2026, 4:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Reducing HIV Risk Among Adolescents: Evaluating Project HEART

NCT02579135
View directory record Official record
Conditions
HIV, Sexually Transmitted Diseases
Interventions
Safer Sex, Growth Mindsets
Behavioral
Lead sponsor
North Carolina State University
Other
Eligibility
14 Years to 18 Years · Female only
Enrollment
222 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 15, 2018 · Synced Sep 24, 2026, 4:29 AM EDT
Completed Not applicable Interventional

Pepped on Pre-exposure Prophylaxis (PrEP): A Counseling and Problem-Solving PrEP Adherence Intervention for Stimulant Using Men Who Have Sex With Men (MSM).

NCT03137342
View directory record Official record
Conditions
PrEP Uptake, Stimulant Abuse, Adherence, Medication
Interventions
Pepped on PrEP Package
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older · Male only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 10, 2018 · Synced Sep 24, 2026, 4:29 AM EDT
Completed Phase 2 Interventional

Effectiveness of Structured Ecosystems Therapy for Reducing HIV Risk Behaviors and Improving Treatment Adherence in HIV Infected Men Released From Prison

NCT00344591
View directory record Official record
Conditions
HIV Infections, Acquired Immunodeficiency Syndrome
Interventions
Structured Ecosystems Therapy (SET), Individually tailored intervention
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Male only
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2005
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 23, 2015 · Synced Sep 24, 2026, 4:29 AM EDT
Not listed Phase 1 Interventional

Behavioral Activation and HIV Risk Reduction for Men Who Have Sex With Men With Crystal Meth Abuse

NCT01255280
View directory record Official record
Conditions
Crystal Methamphetamine Abuse, Crystal Methamphetamine Dependence
Interventions
Behavioral Activation Therapy and Risk Reduction Counseling (BAT-RR), Information, Motivation, Behavioral skills change approach to sexual risk reduction
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Male only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 31, 2012 · Synced Sep 24, 2026, 4:29 AM EDT
Completed Not applicable Interventional Results available

Testing a Community-Friendly Risk Reduction Intervention for Injection Drug Users

NCT01741350
View directory record Official record
Conditions
HIV, Opioid Dependence
Interventions
Community-friendly Health Recovery Program, Time-and-Attention-Matched Control Condition
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years and older
Enrollment
304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 24, 2026, 4:29 AM EDT