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ClinicalTrials.gov public records Last synced Oct 26, 2026, 2:22 PM EDT

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Showing 1–24 of 183 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Sexual risk reduction intervention Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Game Plan for PrEP

NCT04973267
View directory record Official record
Conditions
Human Immunodeficiency Virus Exposure, Alcohol; Harmful Use
Interventions
Game Plan for PrEP, Attention-Matched Control Lifestyle Habits Videos
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older · Male only
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 28, 2024 · Synced Oct 26, 2026, 2:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project Legacy Impact Evaluation Study

NCT03366636
View directory record Official record
Conditions
Pregnancy Prevention, Sexual Behavior, Contraception Behavior, Sexually Transmitted Diseases
Interventions
Project Legacy
Behavioral
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
14 Years to 19 Years
Enrollment
571 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
12
States / cities
Boyle Heights, California • Long Beach, California • Los Angeles, California + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 3, 2024 · Synced Oct 26, 2026, 2:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

HORIZONS HIV Intervention

NCT00633906
View directory record Official record
Conditions
HIV Infections, Sexually Transmitted Diseases
Interventions
HORIZONS HIV Intervention, enhanced standard-of-care
Behavioral
Lead sponsor
Emory University
Other
Eligibility
15 Years to 21 Years · Female only
Enrollment
715 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2005
U.S. locations
3
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 19, 2013 · Synced Oct 26, 2026, 2:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Group Therapies for Reducing HIV-risk Behavior in Women Who Have Survived Childhood Sexual Abuse

NCT00220597
View directory record Official record
Conditions
Alcoholism, Child Abuse, Sexual, Sexual Abuse, Sexual Behavior, Sexually Transmitted Diseases, Viral
Interventions
Trauma-focused group therapy
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
171 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2004
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 3, 2013 · Synced Oct 26, 2026, 2:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

An Innovative HIV Prevention Intervention Using Social Networking Technology

NCT01381653
View directory record Official record
Conditions
Sexual Risk, Substance Use
Interventions
Behavioral: HIV prevention intervention
Other
Lead sponsor
Hunter College of City University of New York
Other
Eligibility
18 Years to 29 Years · Male only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 3, 2013 · Synced Oct 26, 2026, 2:22 PM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

Novel Internet-Based Interventions to Reduce Sexual Risk Among Men Who Have Sex With Men

NCT00649701
View directory record Official record
Conditions
HIV Infections
Interventions
Standard Text-Based Prevention Web Page, The Morning After, Talking About HIV, Both Videos
Behavioral
Lead sponsor
Public Health Solutions
Other
Eligibility
18 Years and older · Male only
Enrollment
3,097 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 20, 2008 · Synced Oct 26, 2026, 2:22 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Effectiveness of an HIV Prevention Program That Targets the Inner Workings of High-risk Social Networks

NCT00705705
View directory record Official record
Conditions
HIV Infections
Interventions
Network leader training, Standard HIV risk-reduction counseling
Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
852 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 11, 2011 · Synced Oct 26, 2026, 2:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Trial of an Adapted STD Screening and Risk Reduction Intervention

NCT02513225
View directory record Official record
Conditions
Alcohol Use, Drug Use, Diagnostic Self Evaluation, Gonorrhea, Unprotected Sex, Chlamydia, Trichomonas
Interventions
Project EMPWR, Optimized Standard Care (OSC)
Behavioral · Other
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years to 49 Years
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Fort Apache, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 26, 2026, 2:22 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Gathering Online for Dialogue and Discussion to Enhance Social Support

NCT05753683
View directory record Official record
Conditions
Alcohol Misuse, HIV, Sexually Transmitted Infections, Pre-exposure Prophylaxis
Interventions
mHealth-Women's CoOp, Virtual Group
Behavioral
Lead sponsor
RTI International
Other
Eligibility
18 Years to 30 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Oct 26, 2026, 2:22 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Computer-Assisted Tailored Cue-card Health [CATCH] Study

NCT01170741
View directory record Official record
Conditions
Human Immunodeficiency Virus, STDs, Hepatitis, Viral, Human
Interventions
Tailored Cue Cards
Behavioral
Lead sponsor
RTI International
Other
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 25, 2012 · Synced Oct 26, 2026, 2:22 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

WHC+ (Women's Health CoOp PLUS)

NCT01497405
View directory record Official record
Conditions
HIV, Sexual Risk, Sexually Transmitted Diseases, Substance Abuse, Violence, Victimization
Interventions
Test, Treat, Retain(TTR) + Women's Health CoOp (WHC), Test, Treat, Retain(TTR) only
Behavioral · Biological
Lead sponsor
RTI International
Other
Eligibility
15 Years to 55 Years · Female only
Enrollment
641 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Research Triangle Park, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced Oct 26, 2026, 2:22 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

HIV Prevention Among At-risk Latinos in the Heartland

NCT04563715
View directory record Official record
Conditions
HIV Infections
Interventions
HIV counseling and testing, Network intervention
Diagnostic Test · Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older · Male only
Enrollment
456 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
3
States / cities
Indianapolis, Indiana • Cleveland, Ohio • Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 3, 2021 · Synced Oct 26, 2026, 2:22 PM EDT
Completed Not applicable Interventional

Risk Reduction for Drug Use and Sexual Revictimization

NCT00998153
View directory record Official record
Conditions
Risk Reduction Through Family Therapy, Usual Care
Interventions
Risk Reduction through Family Therapy
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
12 Years to 17 Years
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 18, 2018 · Synced Oct 26, 2026, 2:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Substance Use and Sexual Risk Reduction Intervention for Homeless Youth

NCT02188797
View directory record Official record
Conditions
Substance Use, Sexual Risk Behavior
Interventions
Group MI risk reduction program
Behavioral
Lead sponsor
RAND
Other
Eligibility
18 Years to 24 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
2
States / cities
Hollywood, California • Venice Beach, California
Source: ClinicalTrials.gov public record
Updated Apr 19, 2016 · Synced Oct 26, 2026, 2:22 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Alcohol Health Education With Personalized Feedback Boosters

NCT03440463
View directory record Official record
Conditions
College Student Drinking
Interventions
e-checkup to go, Norms-only booster, Norms-plus-Strategies booster
Behavioral
Lead sponsor
Abby Braitman
Other
Eligibility
18 Years to 24 Years
Enrollment
528 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 22, 2023 · Synced Oct 26, 2026, 2:22 PM EDT
Completed Phase 1 Interventional

Telephone-delivered Behavioral Interventions to Reduce Risky Sexual Behavior in HIV-positive Late Middle-age and Older Adults

NCT01499706
View directory record Official record
Conditions
Unsafe Sex
Interventions
1-session of telephone-administered motivational interviewing, 4-session telephone-administered motivational interviewing
Behavioral
Lead sponsor
Ohio University College of Osteopathic Medicine
Other
Eligibility
45 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Athens, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 26, 2011 · Synced Oct 26, 2026, 2:22 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

Reducing HIV: Safer Sex Skill Building in Pregnant Drug Abusing Women

NCT00619320
View directory record Official record
Conditions
HIV Infections, Substance Use
Interventions
Safer Sex Skills Building (SSB)
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older · Female only
Enrollment
380 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
2
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 12, 2013 · Synced Oct 26, 2026, 2:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Culturally-Tailored HIV Risk Reduction for African-American MSM

NCT00691561
View directory record Official record
Conditions
HIV Infections
Interventions
Project ABLE
Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older · Male only
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 11, 2010 · Synced Oct 26, 2026, 2:22 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

DOT Diary Mobile App for Pre-Exposure Prophylaxis Adherence in Young Men

NCT03771638
View directory record Official record
Conditions
Adherence, Medication, Risk Behavior, Pre-Exposure Prophylaxis, HIV Prevention
Interventions
Emtricitabine / Tenofovir Disoproxil Oral Tablet, DOT Diary mobile app
Drug · Other
Lead sponsor
Public Health Foundation Enterprises, Inc.
Other
Eligibility
18 Years to 35 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
2
States / cities
San Francisco, California • Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 3, 2025 · Synced Oct 26, 2026, 2:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adaptation and Implementation of Project Encuentro in the U.S.-Mexico Border

NCT03293875
View directory record Official record
Conditions
HIV
Interventions
Community Events, Social Network HIV Testing, Peer Network Intervention
Behavioral
Lead sponsor
City University of New York
Other
Eligibility
18 Years and older
Enrollment
840 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Sep 26, 2025 · Synced Oct 26, 2026, 2:22 PM EDT
Completed Not applicable Interventional Results available

Testing an Integrated Bio-Behavioral Primary HIV Prevention Intervention Among High-Risk People Who Use Drugs

NCT03282890
View directory record Official record
Conditions
Risk Behavior, HIV/AIDS, Medication Adherence, Substance Abuse
Interventions
CHRP-BB
Other
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years and older
Enrollment
237 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 17, 2025 · Synced Oct 26, 2026, 2:22 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Reducing HIV Risk Among Episodic Substance Using Men Who Have Sex With Men (SUMSM)

NCT01279044
View directory record Official record
Conditions
HIV Infections, Episodic Substance Use
Interventions
Adapted Personalized Cognitive Risk-reduction Counseling intervention (PCC), Standard HIV testing with information only
Behavioral
Lead sponsor
San Francisco Department of Public Health
Government
Eligibility
18 Years and older · Male only
Enrollment
385 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 7, 2014 · Synced Oct 26, 2026, 2:22 PM EDT
Completed Phase 1 Interventional

HIV Prevention in Very High Risk Men Who Have Sex With Men

NCT01291589
View directory record Official record
Conditions
Risk Reduction Behavior
Interventions
Cognitive-behavioral therapy
Behavioral
Lead sponsor
Fenway Community Health
Other
Eligibility
18 Years and older · Male only
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 9, 2016 · Synced Oct 26, 2026, 2:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project UNITY - HIV Risk Reduction and Vaccine Education Interventions

NCT00150098
View directory record Official record
Conditions
HIV Infections, Hepatitis B
Interventions
Enhanced HIV risk reduction and HIV vaccine education
Behavioral
Lead sponsor
New York Blood Center
Other
Eligibility
18 Years and older · Female only
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2010
U.S. locations
2
States / cities
New York, New York • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 8, 2014 · Synced Oct 26, 2026, 2:22 PM EDT