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ClinicalTrials.gov public records Last synced Oct 3, 2026, 8:51 AM EDT

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Showing 25–48 of 78 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Sexually transmitted infection testing: Clear all
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Integrated Health Services (IHS): A Structural Intervention to Improve HIV/STI Screening and PrEP Navigation in Primary Care

NCT07446764
View directory record Official record
Conditions
HIV, STDs
Interventions
Integrated HIV/STI Testing and PrEP Navigation Model
Behavioral
Lead sponsor
My Brother's Keeper, Inc.
Other
Eligibility
18 Years to 45 Years
Enrollment
700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2028
U.S. locations
1
States / cities
Ridgeland, Mississippi
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Oct 3, 2026, 8:51 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Getting to Zero Among HHI MSM in the American South

NCT05075967
View directory record Official record
Conditions
HIV Infections
Interventions
Health Access Coalitions, Social Media, Peer Support, Promoting Human Autonomy Support & Empathy (PHASE)
Behavioral
Lead sponsor
HIV Prevention Trials Network
Network
Eligibility
15 Years and older · Male only
Enrollment
2,700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 3, 2026, 8:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Ending the HIV Epidemic Through Point-of-Care Technologies (EHPOC)

NCT04793750
View directory record Official record
Conditions
HIV Infections, Syphilis
Interventions
Cepheid GeneXpert HIV-1 Qual POC HIV VL test, DPP HIV-Syphilis test system, OraQuick
Diagnostic Test
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
224 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
3
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Oct 3, 2026, 8:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility Testing a Meditation App for Youth in the Legal System

NCT05146167
View directory record Official record
Conditions
Behavioral Health
Interventions
Bodhi AIM (intervention group), HIB (control group)
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
13 Years to 18 Years
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 3, 2026, 8:51 AM EDT
Completed Not applicable Interventional Results available

Zenyth: Motivational Interviewing-based Telehealth Intervention for Bacterial Sexually Transmitted Infection Screening

NCT06100250
View directory record Official record
Conditions
Sexually Transmitted Diseases, Gonorrhea, Chlamydia, Syphilis, HIV
Interventions
Motivational interviewing and specimen self-collection
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 1, 2025 · Synced Oct 3, 2026, 8:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Home Self-Testing for HIV to Increase HIV Testing Frequency in Men Who Have Sex With Men (The iTest Study)

NCT01161446
View directory record Official record
Conditions
HIV
Interventions
Home HIV self-testing with OraQuick ADVANCE® Rapid HIV-1/2 Antibody Test, Home HIV self-testing with OraQuick ADVANCE® Rapid HIV-1/2 Antibody Test
Behavioral · Device
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older · Male only
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 7, 2017 · Synced Oct 3, 2026, 8:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Assessing the Feasibility and Preliminary Impact of a mHealth App on Reducing STI Risk in Black MSM PrEP Users

NCT05395754
View directory record Official record
Conditions
STI, Sexually Transmitted Diseases, Pre-exposure Prophylaxis
Interventions
App Intervention
Device
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Oct 3, 2026, 8:51 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Evaluation of Doxycycline Post-exposure Prophylaxis to Reduce Sexually Transmitted Infections in PrEP Users and HIV-infected Men Who Have Sex With Men

NCT03980223
View directory record Official record
Conditions
Gonorrhea, Chlamydia, Syphilis
Interventions
Doxycycline Hyclate Delayed-Release 200 mg
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Male only
Enrollment
641 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
3
States / cities
San Francisco, California • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 12, 2024 · Synced Oct 3, 2026, 8:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mobile Enhanced Prevention Support for People Leaving Jail

NCT04036396
View directory record Official record
Conditions
HIV Infections, Sexually Transmitted Diseases, Bacterial, Hepatitis C, Substance Use Disorders
Interventions
Mobile Enhanced Prevention Support, Usual Care plus Customized Referrals
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 49 Years · Male only
Enrollment
233 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
3
States / cities
Los Angeles, California • Santa Fe Springs, California
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 3, 2026, 8:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mobile-Based Application "MyChoices"

NCT03179319
View directory record Official record
Conditions
HIV, Sexually Transmitted Diseases, Pre-exposure Prophylaxis, Risk Reduction
Interventions
MyChoices
Behavioral
Lead sponsor
Fenway Community Health
Other
Eligibility
15 Years to 24 Years · Male only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
2
States / cities
Boston, Massachusetts • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Dec 16, 2020 · Synced Oct 3, 2026, 8:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reality Check: An HIV Risk Reduction Serial Drama

NCT03352219
View directory record Official record
Conditions
HIV (Human Immunodeficiency Virus), Sexually Transmitted Diseases
Interventions
Reality Check, Physical Activity Attention Control
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 24 Years
Enrollment
203 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 24, 2017 · Synced Oct 3, 2026, 8:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sexual Health Texting Intervention to Support Adolescent Females

NCT02419690
View directory record Official record
Conditions
Teen Sexual Health
Interventions
text message intervention
Behavioral
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
13 Years to 18 Years · Female only
Enrollment
244 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 10, 2020 · Synced Oct 3, 2026, 8:51 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Penicillin Allergy Testing in STD Clinics

NCT04620746
View directory record Official record
Conditions
Penicillin Allergy
Interventions
Penicillin Major Determinant (PrePen) Skin Testing, Direct Oral challenge
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
284 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
2
States / cities
New Orleans, Louisiana • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 21, 2023 · Synced Oct 3, 2026, 8:51 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

WHC+ (Women's Health CoOp PLUS)

NCT01497405
View directory record Official record
Conditions
HIV, Sexual Risk, Sexually Transmitted Diseases, Substance Abuse, Violence, Victimization
Interventions
Test, Treat, Retain(TTR) + Women's Health CoOp (WHC), Test, Treat, Retain(TTR) only
Behavioral · Biological
Lead sponsor
RTI International
Other
Eligibility
15 Years to 55 Years · Female only
Enrollment
641 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Research Triangle Park, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced Oct 3, 2026, 8:51 AM EDT
Completed Not applicable Interventional Results available

Spotting Syphilis: A Dual Point-of-Care Syphilis Screening Initiative in a Low-Resource Healthcare Setting

NCT07498153
View directory record Official record
Conditions
Syphilis, HIV Infections
Interventions
Chembio HIV/Syphilis rapid POC test
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
14 Years to 65 Years · Female only
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 3, 2026, 8:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The S.A.F.E. Study : Computer-Aided Counseling to Prevent Teen Pregnancy/Sexually Transmitted Diseases (STDs)

NCT00151151
View directory record Official record
Conditions
Pregnancy, Sexually Transmitted Diseases
Interventions
Computer-Assisted Motivational Intervention, Didactic Educational Counseling
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
13 Years to 21 Years · Female only
Enrollment
660 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2007
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 13, 2011 · Synced Oct 3, 2026, 8:51 AM EDT
Recruiting Not applicable Interventional

Point of Care STI Testing

NCT06844045
View directory record Official record
Conditions
Point of Care STI Testing
Interventions
Gonorrhea/chlamydia Point-of-Care Testing
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
16 Years to 24 Years
Enrollment
6,460 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 3, 2026, 8:51 AM EDT
Recruiting Phase 4 Interventional

Doxycycline Prophylaxis for Prevention of Sexually Transmitted Infections

NCT06738407
View directory record Official record
Conditions
Gonorrhea, Chlamydia, Syphilis, Sexually Transmitted Infections (STIs)
Interventions
Doxycycline hyclate delayed released 200 mg, Doxycycline hyclate delayed released 200 mg weekly, Per standard of care with quarterly STI testing/treatment and sexual health counseling
Drug · Other
Lead sponsor
Westat
Other
Eligibility
13 Years to 29 Years · Female only
Enrollment
760 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
13
States / cities
Los Angeles, California • San Francisco, California • Washington D.C., District of Columbia + 10 more
Source: ClinicalTrials.gov public record
Updated May 15, 2026 · Synced Oct 3, 2026, 8:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Louisville Teen Pregnancy Prevention Project

NCT01411878
View directory record Official record
Conditions
Pregnancy, Sexually Transmitted Diseases
Interventions
Reducing the Risk, Love Notes
Behavioral
Lead sponsor
University of Louisville
Other
Eligibility
14 Years to 19 Years
Enrollment
1,450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
12
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 24, 2017 · Synced Oct 3, 2026, 8:51 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Use of a Rapid Test for Gonorrhea & Chlamydia for Women Presenting With Possible Sexually Transmitted Infections

NCT03098394
View directory record Official record
Conditions
Sexually Transmitted Infection, Gonorrhea Female, Chlamydia Females
Interventions
Cepheid Xpert CT/NG Rapid Turnaround Test, Polymerase chain reaction (PCR)
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 31, 2023 · Synced Oct 3, 2026, 8:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Game Plan: Efficacy of a Brief, Web-based Intervention on Alcohol Use and Sexually-transmitted Infections

NCT04552171
View directory record Official record
Conditions
Sexually Transmitted Diseases, Bacterial, Alcohol; Harmful Use
Interventions
Access to Game Plan app and 24-hour helpline
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older · Male only
Enrollment
314 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 3, 2026, 8:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Positive Prevention PLUS Program

NCT02540278
View directory record Official record
Conditions
Pregnancy in Adolescence
Interventions
Positive Prevention PLUS
Behavioral
Lead sponsor
California State University, San Bernardino
Other
Eligibility
12 Years to 19 Years
Enrollment
4,267 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
San Bernardino, California
Source: ClinicalTrials.gov public record
Updated Sep 3, 2015 · Synced Oct 3, 2026, 8:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Young Women's Health CoOp (Cooperative) in Cape Town

NCT02677025
View directory record Official record
Conditions
HIV, Substance Abuse
Interventions
Young Women's Health CoOp (YWHC), HIV Counseling/Testing
Behavioral
Lead sponsor
RTI International
Other
Eligibility
16 Years to 21 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Research Triangle Park, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced Oct 3, 2026, 8:51 AM EDT
Not yet recruiting Not applicable Interventional

Implementation of an Opt-Out Testing and Rapid Diagnostic Strategy for Syphilis and HIV in Pregnant Patients Presenting to the Emergency Department

NCT07525076
View directory record Official record
Conditions
HIV Infections, Syphilis Infection
Interventions
Chembio HIV/Syphilis rapid Point of Care (POC) test, Laboratory-based HIV and syphilis testing
Diagnostic Test
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
14 Years to 45 Years · Female only
Enrollment
1,400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 3, 2026, 8:51 AM EDT