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ClinicalTrials.gov public records Last synced Oct 17, 2026, 4:27 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 3,877 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Sham Clear all
Recruiting Not applicable Interventional

Locomotor Function Following Transcutaneous Electrical Spinal Cord Stimulation in Individuals With Hemiplegic Stroke

NCT05167786
View directory record Official record
Conditions
Stroke
Interventions
Noninvasive spinal stimulation with gait training, Conventional gait training, Exploratory Phase - Optimization of Gait Training and Spinal Stimulation
Device · Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years and older
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Oct 17, 2026, 4:27 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

tVNS During Motor Training in Older Adults

NCT06323954
View directory record Official record
Conditions
Older Adults
Interventions
tVNS stimulation, Sham stimulation
Procedure
Lead sponsor
Georgia Institute of Technology
Other
Eligibility
65 Years to 84 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 17, 2026, 4:27 AM EDT
Completed Not applicable Interventional

Effect of Transcutaneous Vagal Stimulation (TVS) on Endothelial Function in PAD

NCT03445754
View directory record Official record
Conditions
Peripheral Artery Disease, Endothelial Dysfunction, Autonomic Imbalance
Interventions
TVS, Sham TVS
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 85 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Oct 17, 2026, 4:27 AM EDT
Recruiting Phase 4 Interventional

Travoprost Intraocular Implant + iStent Infinite

NCT06066645
View directory record Official record
Conditions
Glaucoma, Open-Angle
Interventions
Travoprost Intraocular Implant, iStent infinite, Sham procedure
Drug · Device · Other
Lead sponsor
Glaukos Corporation
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 17, 2026, 4:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Low Intensity Ultrasound Neuromodulation of Repetitive Negative Thinking In Depression

NCT05697172
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Low-intensity focused ultrasound
Other
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 5, 2024 · Synced Oct 17, 2026, 4:27 AM EDT
Completed Not applicable Interventional Results available

Trial of Low Field Magnetic Stimulation Augmentation of Antidepressant Therapy in Treatment-Resistant Depression

NCT01654796
View directory record Official record
Conditions
Treatment Resistant Depression
Interventions
Low Field Magnetic Stimulation (LFMS), Sham LFMS
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
6
States / cities
Birmingham, Alabama • New Haven, Connecticut • Atlanta, Georgia + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 5, 2017 · Synced Oct 17, 2026, 4:27 AM EDT
Not listed Not applicable Interventional

Peripheral Nerve Stimulation Therapy for Atrial Fibrillation

NCT05653583
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Wrist Device, Ear Device, Sham Device
Device
Lead sponsor
Cala Health, Inc.
Industry
Eligibility
22 Years to 79 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
2
States / cities
Rochester, Minnesota • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Oct 17, 2026, 4:27 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Handgrip Training and Brain Blood Flow Regulation

NCT07223645
View directory record Official record
Conditions
Inactivity/Low Levels of Exercise
Interventions
Handgrip Training
Device
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 35 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 17, 2026, 4:27 AM EDT
Completed Not applicable Interventional

tDCS and Aphasia Treatment

NCT01922245
View directory record Official record
Conditions
Aphasia
Interventions
Soterix 1x1 tDCS
Device
Lead sponsor
Hunter College of City University of New York
Other
Eligibility
18 Years to 100 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 14, 2020 · Synced Oct 17, 2026, 4:27 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

How Does Vagus Nerve Stimulation Affect Blood Glucose, Food, and Movement Cravings?

NCT07457372
View directory record Official record
Conditions
Vagus Nerve Stimulation
Interventions
Active taVNS, Sham taVNS
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 35 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Duluth, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 17, 2026, 4:27 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Brain Stimulation to the Hippocampus in Schizophrenia

NCT07010614
View directory record Official record
Conditions
Schizophrenia Disorders, Mental Disorder, Psychotic Disorder
Interventions
Intracranial electrodes, TMS, TMS sham
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 17, 2026, 4:27 AM EDT
Completed Not applicable Interventional

Dry Needling and Stretching vs. Stretching Alone on Hamstring Flexibility in Patients With Knee Pain

NCT02498704
View directory record Official record
Conditions
Mobility Limitation
Interventions
Dry Needling, Sham Needling
Procedure · Other
Lead sponsor
Keller Army Community Hospital
Federal
Eligibility
18 Years to 40 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
West Point, New York
Source: ClinicalTrials.gov public record
Updated Feb 23, 2016 · Synced Oct 17, 2026, 4:27 AM EDT
Recruiting Phase 2 Interventional

A Single Dose of BRTX 100 for Patients With Chronic Lumbar Disc Disease (cLDD)

NCT04042844
View directory record Official record
Conditions
Lumbar Disc Disease
Interventions
BRTX-100, Saline
Biological · Drug
Lead sponsor
BioRestorative Therapies
Industry
Eligibility
18 Years and older
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
19
States / cities
Birmingham, Alabama • Santa Monica, California • Walnut Creek, California + 15 more
Source: ClinicalTrials.gov public record
Updated Aug 26, 2025 · Synced Oct 17, 2026, 4:27 AM EDT
Withdrawn Early Phase 1 Interventional Accepts healthy volunteers

tFUS to Enhance Alertness and Performance

NCT06461221
View directory record Official record
Conditions
Reaction Time, Alertness
Interventions
Transcranial Focused Ultrasound
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
22 Years to 55 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Oct 17, 2026, 4:27 AM EDT
Completed Not applicable Interventional Results available

Combined Peripheral (BreEStim) and Central Electrical Stimulation (tDCS) for Neuropathic Pain Management - Spinal Cord Injury

NCT03302793
View directory record Official record
Conditions
Pain Management
Interventions
BreEStim, tDCS, tDCS sham
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 75 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 24, 2019 · Synced Oct 17, 2026, 4:27 AM EDT
Completed Phase 3 Interventional Results available

Glutathione in Preventing Peripheral Neuropathy Caused by Paclitaxel and Carboplatin in Patients With Ovarian Cancer, Fallopian Tube Cancer, and/or Primary Peritoneal Cancer

NCT02311907
View directory record Official record
Conditions
Chemotherapeutic Agent Toxicity, Neuropathy, Neurotoxicity Syndrome, Pain, Stage IIIA Fallopian Tube Cancer, Stage IIIA Ovarian Cancer, Stage IIIA Primary Peritoneal Cancer, Stage IIIB Fallopian Tube Cancer, Stage IIIB Ovarian Cancer, Stage IIIB Primary Peritoneal Cancer, Stage IIIC Fallopian Tube Cancer, Stage IIIC Ovarian Cancer, Stage IIIC Primary Peritoneal Cancer, Stage IV Fallopian Tube Cancer, Stage IV Ovarian Cancer, Stage IV Primary Peritoneal Cancer
Interventions
Carboplatin, Glutathione, Laboratory Biomarker Analysis, Paclitaxel, Placebo, Quality-of-Life Assessment
Drug · Other
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
18 Years and older
Enrollment
195 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
390
States / cities
Mobile, Alabama • Fairbanks, Alaska • Scottsdale, Arizona + 259 more
Source: ClinicalTrials.gov public record
Updated Feb 23, 2017 · Synced Oct 17, 2026, 4:27 AM EDT
Not listed Not applicable Interventional

tDCS and Impulsivity

NCT05845164
View directory record Official record
Conditions
Substance Use Disorders, Substance Abuse, Substance Use
Interventions
tDCS, tDCS Sham
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 79 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated May 6, 2023 · Synced Oct 17, 2026, 4:27 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

INSIGHT: Insomnia, Nightmares, and Sympathetic Hyperactivity Intervention

NCT07288593
View directory record Official record
Conditions
Nightmare, Insomnia, PTSD, TBI, Sleep Disorder (Disorder), REM Behavior Disorder
Interventions
NightWare smartwatch configured to detect physiological signs of sympathetic activation during sleep, such as heart-rate spikes and movement patterns., Sham (No Treatment)
Device
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 62 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Bethesda, Maryland • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 17, 2026, 4:27 AM EDT
Completed Not applicable Interventional

Effects of Whole Body Vibration on Quadriceps Function, Landing Biomechanics, and Performance in Individuals With ACL Reconstruction

NCT07681193
View directory record Official record
Conditions
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Tear, ACL Injury, ACL Tear, Biomechanical Phenomena
Interventions
Whole body vibration (WBV), Sham Whole body vibration
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 35 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 2, 2026 · Synced Oct 17, 2026, 4:27 AM EDT
Completed Not applicable Interventional

Evaluation of the TheraNova Neuromodulation System for the Treatment of Overactive Bladder Symptoms

NCT04758247
View directory record Official record
Conditions
Overactive Bladder
Interventions
TheraNova Neuromodulation System
Device
Lead sponsor
Theranova, L.L.C.
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
2
States / cities
Sacramento, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 28, 2024 · Synced Oct 17, 2026, 4:27 AM EDT
Completed Not applicable Interventional

Study of the Carbon Dioxide Treatment for Fat Reduction

NCT00974415
View directory record Official record
Conditions
Overweight
Interventions
CO2, Sham
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 17, 2026, 4:27 AM EDT
Not listed Not applicable Interventional

tDCS and Cognitive Training for Mild Cognitive Impairment and Alzheimer's Dementia

NCT04507815
View directory record Official record
Conditions
Alzheimer Disease, Mild Cognitive Impairment
Interventions
Active Transcranial Direct Current Stimulation (tDCS), Sham Transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
Minneapolis Veterans Affairs Medical Center
Federal
Eligibility
60 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 14, 2023 · Synced Oct 17, 2026, 4:27 AM EDT
Completed Not applicable Interventional Results available

Auricular Acupuncture For The Treatment Of Non-Epileptic Seizures

NCT01919307
View directory record Official record
Conditions
Convulsion, Non-Epileptic
Interventions
Auricular acupuncture
Other
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
18 Years to 75 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 5, 2018 · Synced Oct 17, 2026, 4:27 AM EDT
Terminated Not applicable Interventional

Transcranial Magnetic Stimulation (TMS) in the Treatment of Anorexia Nervosa

NCT05368844
View directory record Official record
Conditions
Anorexia Nervosa
Interventions
rTMS treatment using BrainsWay Model 104 system with H1-Coil, sham TMS using BrainsWay Model 104 system with H1-Coil
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 17, 2026, 4:27 AM EDT