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ClinicalTrials.gov public records Last synced Nov 4, 2026, 10:12 AM EST

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Showing 1273–1296 of 1,663 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Sham (Control) Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Brain Stimulation on Higher-Order Cognition

NCT03814967
View directory record Official record
Conditions
Schizophrenia
Interventions
Transcranial Direct Current Stimulation
Device
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 50 Years
Enrollment
86 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 29, 2025 · Synced Nov 4, 2026, 10:12 AM EST
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Theta-Burst Stimulation as a Treatment for Reducing Cocaine Use

NCT02927236
View directory record Official record
Conditions
Cocaine Use Disorder, Cocaine Dependence
Interventions
Transcranial magnetic stimulation (TMS)
Device
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
22 Years to 60 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 25, 2025 · Synced Nov 4, 2026, 10:12 AM EST
Completed No phase listed Observational

Effectiveness and Acceptability of Stellate Ganglion Block for Posttraumatic Stress Disorder Symptoms - Acceptability

NCT03302312
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Not listed
Lead sponsor
RTI International
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
Honolulu, Hawaii • Fort Bragg, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 30, 2018 · Synced Nov 4, 2026, 10:12 AM EST
Suspended Not applicable Interventional

Acute Study of Effect of Ultrasound Vagus Nerve Stimulation on Glycemia

NCT04094649
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Ultrasound Vagus Nerve Stimulation (DECIMA)
Device
Lead sponsor
Aucta Technologies, Inc.
Industry
Eligibility
21 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 20, 2021 · Synced Nov 4, 2026, 10:12 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

DB RCT for Specialized Phototherapy in Parkinson's Disease.

NCT04453033
View directory record Official record
Conditions
Parkinson Disease
Interventions
Celeste Specialized Phototherapy Device
Device
Lead sponsor
PhotoPharmics, Inc.
Industry
Eligibility
45 Years and older
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Nov 4, 2026, 10:12 AM EST
Completed Not applicable Interventional Results available

EEG Biofeedback Therapy as an Adjunct Treatment for PTSD

NCT01591408
View directory record Official record
Conditions
PTSD, Anxiety, Trauma, Sleep Disorders
Interventions
EEG biofeedback
Device
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years to 40 Years · Male only
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 20, 2016 · Synced Nov 4, 2026, 10:12 AM EST
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Investigation and Modulation of the Mu-opioid Mechanisms in TMD (in Vivo)

NCT03724032
View directory record Official record
Conditions
Temporomandibular Disorder
Interventions
HD-tDCS*, Sham HD-tDCS*
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 15, 2023 · Synced Nov 4, 2026, 10:12 AM EST
Completed Phase 3 Interventional

Transdermal Patch for BupRenorphine Induction DurinG PrEgnancy (Patch BRIDGE)

NCT05790252
View directory record Official record
Conditions
Opioid Use Disorder, Pregnancy Related, Pregnancy, High Risk, Pregnancy Complications, Buprenorphine Withdrawal
Interventions
Buprenorphine Transdermal Matrix Patch, Sham patch
Drug · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 110 Years · Female only
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Nov 4, 2026, 10:12 AM EST
Completed Phase 3 Interventional Results available

A Study to Determine the Safety and Efficacy of NT-501 in Macular Telangiectasia Type 2 - Protocol B

NCT03319849
View directory record Official record
Conditions
Macular Telangiectasia Type 2
Interventions
NT-501, Sham
Combination Product · Procedure
Lead sponsor
Neurotech Pharmaceuticals
Industry
Eligibility
21 Years to 80 Years
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
22
States / cities
Beverly Hills, California • Colorado Springs, Colorado • Atlanta, Georgia + 18 more
Source: ClinicalTrials.gov public record
Updated Sep 24, 2024 · Synced Nov 4, 2026, 10:12 AM EST
Completed Not applicable Interventional Results available

Treatment of Post-Operative Pain Following Orthopedic Surgery With SPRINT® Peripheral Nerve Stimulation (PNS) System

NCT04341948
View directory record Official record
Conditions
Postoperative Pain, Total Knee Replacement, Total Knee Arthroplasty, Partial Knee Replacement
Interventions
SPRINT Peripheral Nerve Stimulation (PNS) System
Device
Lead sponsor
SPR Therapeutics, Inc.
Industry
Eligibility
21 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
10
States / cities
Little Rock, Arkansas • San Diego, California • Gainesville, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Nov 4, 2026, 10:12 AM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

Overnight Thalamic TES-TI to Modulate Sleep Spindles in Individuals With Schizophrenia Spectrum Disorders and Matched Healthy Controls

NCT07680114
View directory record Official record
Conditions
Schizophrenia
Interventions
TES-TI, Sham TES-TI
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Nov 4, 2026, 10:12 AM EST
Completed Not applicable Interventional

Laser Acupuncture Before and After Embryo Transfer Improves IVF Outcomes

NCT02815371
View directory record Official record
Conditions
Embryo Implantation
Interventions
Needle Acupuncture, Laser Acupuncture, Sham Laser Acupuncture
Procedure
Lead sponsor
Reproductive Medicine Associates of New Jersey
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
803 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
2
States / cities
Norwalk, Connecticut • Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 28, 2016 · Synced Nov 4, 2026, 10:12 AM EST
Recruiting Phase 2 Interventional

A Study to Test Whether BI 764524 Helps People With an Eye Condition Called Diabetic Retinopathy

NCT06321302
View directory record Official record
Conditions
Diabetic Retinopathy
Interventions
BI 764524, Sham comparator to BI 764524, Aflibercept (Eylea®) - US only
Drug
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
18 Years and older
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
40
States / cities
Phoenix, Arizona • Bakersfield, California • Beverly Hills, California + 33 more
Source: ClinicalTrials.gov public record
Updated Oct 28, 2026 · Synced Nov 4, 2026, 10:12 AM EST
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Application of Transcranial Alternating Current Stimulation for Modulation of Sleep and Cognitive Performance

NCT03112902
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Application of Transcranial Alternating Current Stimulation for Modulation of Sleep and Cognitive Performance
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 17, 2021 · Synced Nov 4, 2026, 10:12 AM EST
Terminated Phase 3 Interventional Results available

Safety Study of the VEGA UV-A System to Treat Ectasia

NCT01398839
View directory record Official record
Conditions
Ectasia
Interventions
VEGA UV-A Illumination System, Riboflavin
Device · Drug
Lead sponsor
Topcon Medical Systems, Inc.
Industry
Eligibility
18 Years and older
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
12
States / cities
Phoenix, Arizona • Atlanta, Georgia • Bloomington, Minnesota + 6 more
Source: ClinicalTrials.gov public record
Updated Jun 29, 2022 · Synced Nov 4, 2026, 10:12 AM EST
Suspended Phase 2 Interventional

Dose-Ranging Trial of Inhaled Cannabis for Acute Migraine Treatment

NCT05427630
View directory record Official record
Conditions
Migraine, Cannabis, THC
Interventions
THC ~2.5%, THC ~5%, THC ~10%, Sham Cannabis
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Nov 4, 2026, 10:12 AM EST
Completed Phase 3 Interventional

Epithelium-On Corneal Cross-linking in Subjects 8 to 45 Years of Age With Keratoconus

NCT06100939
View directory record Official record
Conditions
Keratoconus
Interventions
Riboflavin and Sodium Iodide solution and Ultraviolet-A treatment, Placebo and sham treatment
Combination Product
Lead sponsor
Epion Therapeutics
Industry
Eligibility
8 Years to 45 Years
Enrollment
396 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
13
States / cities
Rowland Heights, California • San Francisco, California • Miami, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Nov 4, 2026, 10:12 AM EST
Completed Not applicable Interventional Results available

High-resolution, Relational, Resonance-based, Electroencephalic Mirroring (HIRREM) to Relieve Insomnia

NCT01971567
View directory record Official record
Conditions
Insomnia
Interventions
HIRREM
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 10, 2018 · Synced Nov 4, 2026, 10:12 AM EST
Enrolling by invitation Not applicable Interventional

Prevention and Reduction of Falls: Testing and Evaluating Cutting Edge Haptic Technology

NCT07781397
View directory record Official record
Conditions
Fall Risk, Fall Risk, Fall Prevention, Accidental Falls, Accidental Falls/Prevention & Control
Interventions
LIBERTY Patch, Sham Patch
Device
Lead sponsor
SuperPatch Limited LLC
Industry
Eligibility
55 Years to 85 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Mansfield, Texas
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Nov 4, 2026, 10:12 AM EST
Recruiting Not applicable Interventional

Auricular Neuromodulation in Veterans With Fibromyalgia

NCT06415591
View directory record Official record
Conditions
Fibromyalgia
Interventions
Percutaneous electrical nerve field stimulation
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Nov 4, 2026, 10:12 AM EST
Recruiting Phase 2 Interventional

Extracorporeal Shockwave Therapy as an Additional Treatment for Spasticity Secondary to Spinal Cord Injury

NCT07894991
View directory record Official record
Conditions
Spinal Cord Injury, Spasticity
Interventions
Focused extracorporeal shockwave therapy, Botulinum toxin, Sham
Device · Drug · Other
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 4, 2026 · Synced Nov 4, 2026, 10:12 AM EST
Completed Not applicable Interventional Results available

Sham Controlled Trial of Rapid Induction Percutaneous Tibial Nerve Stimulation

NCT03547518
View directory record Official record
Conditions
Overactive Bladder
Interventions
PTNS treatment, Sham treatment
Device
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Nov 4, 2026, 10:12 AM EST
Recruiting Not applicable Interventional

Imaging Metabolic and Perfusion Changes in Acupuncture Therapy for Myofascial Pain Syndrome

NCT07494162
View directory record Official record
Conditions
Myofascial Pain Syndrome (MPS), Chronic Low-back Pain (cLBP)
Interventions
Acupuncture, Sham Acupuncture, Total-Body PET/CT Imaging
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Nov 4, 2026, 10:12 AM EST
Not listed Phase 2 Interventional

Study of Low-level Laser Therapy in the Acute Treatment of Migraine

NCT02969642
View directory record Official record
Conditions
Migraine Headache
Interventions
Argus Migraine Treatment device
Device
Lead sponsor
The San Francisco Clinical Research Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 2, 2016 · Synced Nov 4, 2026, 10:12 AM EST