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ClinicalTrials.gov public records Last synced Nov 5, 2026, 11:51 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1369–1392 of 1,663 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sham (Control) Clear all

Conditions: Lateral Epicondylitis
Interventions: Blood Flow Restriction Device, Standard Physical Therapy; Device · Other
Lead sponsor: Julie Nuelle; Other
Eligibility: 18 Years to 65 Years
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: Spinal Manipulation, Sham Spinal Manipulation; Other
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years to 55 Years
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Baacterial Colonization, Urinary Tract Infections
Interventions: UroShield; Device
Lead sponsor: Rosenblum, Jonathan I., DPM; Individual
Eligibility: 18 Years and older
Enrollment: 63 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Elmsford, New York

Conditions: Obstructive Sleep Apnea
Interventions: Oral appliance, Oxygen, Oral appliance plus oxygen, No treatment; Device · Drug · Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 21 Years to 79 Years
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Low Back Pain, Myofascial Pain Syndromes
Interventions: Ischemic Compression, Low-Level Laser Therapy, Exercise Program, Sham Low-Level Laser Therapy; Other · Device
Lead sponsor: Nova Southeastern University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Chemotherapeutic Agent Toxicity, Neuropathy, Neurotoxicity Syndrome, Pain, Stage IIIA Fallopian Tube Cancer, Stage IIIA Ovarian Cancer, Stage IIIA Primary Peritoneal Cancer, Stage IIIB Fallopian Tube Cancer, Stage IIIB Ovarian Cancer, Stage IIIB Primary Peritoneal Cancer, Stage IIIC Fallopian Tube Cancer, Stage IIIC Ovarian Cancer, Stage IIIC Primary Peritoneal Cancer, Stage IV Fallopian Tube Cancer, Stage IV Ovarian Cancer, Stage IV Primary Peritoneal Cancer
Interventions: Carboplatin, Glutathione, Laboratory Biomarker Analysis, Paclitaxel, Placebo, Quality-of-Life Assessment; Drug · Other
Lead sponsor: Alliance for Clinical Trials in Oncology; Other
Eligibility: 18 Years and older
Enrollment: 195 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 390
States / cities: Mobile, Alabama • Fairbanks, Alaska • Scottsdale, Arizona + 259 more

Conditions: Parkinson's Disease
Interventions: DSP-1083 implantation, Sham surgery treatment; Combination Product · Procedure
Lead sponsor: Sumitomo Pharma America, Inc.; Industry
Eligibility: 40 Years to 72 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2030
U.S. locations: 3
States / cities: La Jolla, California • Lexington, Kentucky • New York, New York

Conditions: Facial Pain
Interventions: SinuSonic, Sham Device; Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Knee Osteoarthristis, ACL Injuries, Post-Traumatic
Interventions: extracorporeal shockwave therapy (ESWT), Sham Comparator; Device
Lead sponsor: Spaulding Rehabilitation Hospital; Other
Eligibility: 18 Years to 55 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Cambridge, Massachusetts

Conditions: Primary Cervical Dystonia, Dystonia
Interventions: NeuroStar TMS therapy, Sham NeuroStar TMS therapy, Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS), Craniocervical Dystonia Questionnaire (CDQ-24), Cerebellar-brain Inhibition (CBI), Botulinum toxin injections; Device · Other · Procedure
Lead sponsor: University of Florida; Other
Eligibility: 30 Years to 75 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2021
U.S. locations: 2
States / cities: Gainesville, Florida

Conditions: Post Traumatic Stress Disorder
Interventions: Active rTMS, Sham rTMS, Cognitive Processing Therapy; Device · Behavioral
Lead sponsor: The University of Texas at Dallas; Other
Eligibility: 18 Years to 60 Years
Enrollment: 330 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2028
U.S. locations: 3
States / cities: Tallahassee, Florida • Addison, Texas • Dallas, Texas

Conditions: Alzheimer Disease, Dementia
Interventions: tDCS device model Soterix mini-CT (Soterix Medical Inc., New York, NY) programed to deliver active tDCS., tDCS device model Soterix mini-CT (Soterix Medical Inc., New York, NY) programed to deliver sham tDCS.; Device
Lead sponsor: Albert Einstein College of Medicine; Other
Eligibility: 60 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Neurogenic Bladder Due to Spina Bifida
Interventions: Stamobil electric stimulator, sham tTNS device; Device
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 4 Years to 17 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Respiratory Tract Diseases, Cardiovascular Diseases
Interventions: DIY portable air cleaner with a highly effective filter, DIY portable air cleaner with sham filtration; Other
Lead sponsor: Environmental Protection Agency (EPA); Federal
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 1
States / cities: Fresno, California

Conditions: Acupuncture, Pain, Range of Motion
Interventions: One Needle Hand Acupuncture with Movement, One Needle Hand Acupuncture without Movement, Control Acupuncture with Movement; Procedure
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 99 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Chesterfield, Missouri

Conditions: Angelman Syndrome
Interventions: rugonersen, Sham procedure; Drug · Procedure
Lead sponsor: OHB Pediatrics Ltd.; Industry
Eligibility: 1 Year to 50 Years
Enrollment: 165 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 5
States / cities: San Diego, California • Miami, Florida • Chicago, Illinois + 2 more

Conditions: Cardiovascular Diseases, Cardiovascular Risk Factor, Cardiovascular Health
Interventions: Singing with Music Therapist, Singing with Guided Video, Control Arm; Other
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 55 Years to 79 Years
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Abortion in First Trimester
Interventions: Transcutaneous electrical nerve stimulation (TENS), Moderate IV Sedation, SHAM: Transcutaneous electrical nerve stimulation (TENS), SHAM: Moderate IV Sedation; Device · Drug · Other
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 109 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: San Jose, California

Conditions: Overactive Bladder
Interventions: Fesoterodine, Placebo; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 65 Years and older
Enrollment: 566 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 125
States / cities: Birmingham, Alabama • Montgomery, Alabama • Green Valley, Arizona + 106 more

Conditions: Sleep, Sleep Hygiene
Interventions: Transcranial Electrical Stimulation; Device
Lead sponsor: Brain Electrophysiology Laboratory Company; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Eugene, Oregon

Conditions: Sickle Cell Disease
Interventions: Sham 2D Headset Control, Passive Immersive 3D Virtual Reality, Active Immersive Interactive 3D Virtual Reality; Device
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years to 88 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Caregiver
Interventions: Psychosocial Support for Caregiver, Questionnaire Administration, Sham Intervention; Other
Lead sponsor: University of Washington; Other
Eligibility: 19 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Epilepsy
Interventions: Acoustic 1Hz Stimulation, Sham Background Noise; Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 60 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2028
U.S. locations: 1
States / cities: New York, New York

Conditions: Down Syndrome
Interventions: Combined exercise intervention, Usual care / Sham intervention; Behavioral
Lead sponsor: University of Nevada, Las Vegas; Other
Eligibility: 18 Years to 35 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Las Vegas, Nevada

Search by objective public record fields.

Blood Flow Restriction & Tennis Elbow Rehab

Effects of Chiropractic Care on Cytokine Levels in Multiple Sclerosis

The Effect of Surface Acoustic Waves on the Prevention of Colonization in Longterm Indwelling Urinary Caatheters

Combined Upper-airway and Breathing Control Therapies for Obstructive Sleep Apnea

Ischemic Compression and Low-Level Laser Therapy for Myofascial Low Back Pain

Glutathione in Preventing Peripheral Neuropathy Caused by Paclitaxel and Carboplatin in Patients With Ovarian Cancer, Fallopian Tube Cancer, and/or Primary Peritoneal Cancer

A Multicenter Study to Evaluate Safety, Tolerability, and Clinical Responses of DSP-1083 Into Subjects With Parkinson's Disease

Treatment of Sinus Headache Using a Novel Device That Combines Acoustic Vibration With Oscillating Expiratory Pressure

Treatment of Post Traumatic Knee Osteoarthritis With Extracorporeal Shockwave Therapy

rTMS and Botulinum Toxin in Primary Cervical Dystonia

Multi-site Confirmatory Efficacy Treatment Trial of Combat-related PTSD

Neurostimulation for Cognitive Enhancement in Alzheimer's Disease

Tibial Nerve Stimulation for Pediatric Spina Bifida Neurogenic Bladder

ASPIRE Health Tulare County

One Needle Hand Acupuncture for MSK Disorders

BEACON - Phase III Clinical Study of Rugonersen in Angelman Syndrome.

Singing and Cardiovascular Health in Older Adults

Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Control During First Trimester Abortion

A Study Of Efficacy And Safety Of Fesoterodine In Vulnerable Elderly Subjects With Overactive Bladder

Electrical Synchronization of Slow Oscillations to Enhance Deep Sleep

Virtual Reality for SCD VOC

Expressive Writing in Improving the Wellbeing or Comforting Capacity of Caregivers of Patients With Cancer

Acoustic Stimulation for Seizure Suppression

Blood Flow Regulation in Individuals With Down Syndrome - Training Study