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ClinicalTrials.gov public records Last synced Oct 4, 2026, 10:10 AM EDT

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Showing 49–72 of 89 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Sham (no implant) Clear all
Completed Not applicable Interventional

Treatment Study of Soft Palatal Implants in Obstructive Sleep Apnea

NCT00263770
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
soft palate implant, Positive airway pressure (PAP)
Device · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 20, 2011 · Synced Oct 4, 2026, 10:10 AM EDT
Terminated Not applicable Interventional

Condensed Percutaneous Tibial Nerve Stimulation (PTNS) Protocol

NCT03559946
View directory record Official record
Conditions
Overactive Bladder Syndrome
Interventions
percutaneous tibial nerve stimulation (PTNS), Sham procedure
Device
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Oct 4, 2026, 10:10 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Does Percutaneous Tibial Nerve Stimulation (PTNS) Improve Outcomes in Patients Presenting With Fecal Incontinence

NCT01274585
View directory record Official record
Conditions
Fecal Incontinence
Interventions
Posterior tibial nerve stimulation (PTNS), Posterior tibial nerve stimulation
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 5, 2018 · Synced Oct 4, 2026, 10:10 AM EDT
Completed Not applicable Interventional Results available

Clinical Intervention in Alcohol Use Disorder

NCT02168400
View directory record Official record
Conditions
Alcohol Use Disorder, Eligible to go Into the MRI Scanner, Short-term Abstinence From Alcohol Use (2 Week Abstinent)
Interventions
Transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 5, 2024 · Synced Oct 4, 2026, 10:10 AM EDT
Completed Not applicable Interventional Results available

Feasibility of Placing Bravo PH Capsule in Proximal Esophagus

NCT00378898
View directory record Official record
Conditions
Gastroesophageal Reflux Disease
Interventions
BRAVO capsule, Fluoroscopy, sham BRAVO capsule placement
Device · Procedure · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 4, 2017 · Synced Oct 4, 2026, 10:10 AM EDT
Terminated Phase 4 Interventional Results available

Palatal Implants in Combination With Continuous Positive Airway Pressure to Treat Obstructive Sleep Apnea

NCT00730041
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Pillar Palatal Implant System, Sham system
Device
Lead sponsor
Medtronic Xomed, Inc.
Industry
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
7
States / cities
Little Rock, Arkansas • Berkeley, California • Denver, Colorado + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 12, 2010 · Synced Oct 4, 2026, 10:10 AM EDT
Recruiting Not applicable Interventional

taVNS for FRNS in Children

NCT05588063
View directory record Official record
Conditions
Nephrotic Syndrome in Children, Minimal Change Disease, Focal Segmental Glomerulosclerosis
Interventions
Transcutaneous auricular vagus nerve stimulation, Sham device
Device
Lead sponsor
Northwell Health
Other
Eligibility
3 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
New Hyde Park, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Oct 4, 2026, 10:10 AM EDT
Terminated Not applicable Interventional Results available

Acupuncture to Prevent Chemotherapy Dose Reduction Due to Chemotherapy-induced Peripheral Neuropathy in Breast and Colorectal Cancer Patients (GCC1232)

NCT01881932
View directory record Official record
Conditions
Breast Cancer, Colorectal Cancer
Interventions
Acupuncture using Seirin® needles, Sham Acupuncture using Park Sham placebo acupuncture device
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 7, 2019 · Synced Oct 4, 2026, 10:10 AM EDT
Active, not recruiting Phase 2 Interventional

Dual Intravitreal Implantation of NT-501 Encapsulated Cell Therapy for Glaucoma

NCT04577300
View directory record Official record
Conditions
Glaucoma
Interventions
NT-501, Sham comparator
Drug · Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Oct 4, 2026, 10:10 AM EDT
Terminated Not applicable Interventional Results available

Continuous Lumbar Plexus Block With and Without Parasacral Block in Patients Undergoing Total Hip Replacement

NCT02161484
View directory record Official record
Conditions
Osteoarthritis of Hip, Regional Anesthesia, Other Acute Postoperative Pain, Total Hip Arthroplasty, Peripheral Nerve Block, Lumbar Plexus Nerve Block, Parasacaral (Sciatic) Nerve Block
Interventions
Continuous Lumbar Plexus Block, Parasacral Nerve Block, Ropivacine 0.2%, Bupivacaine 0.0625%
Procedure · Drug
Lead sponsor
Rita Merman
Other
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 29, 2018 · Synced Oct 4, 2026, 10:10 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers

Intrauterine Device Insertion Pain Management

NCT06951191
View directory record Official record
Conditions
IUD Insertion Pain, IUD Insertion
Interventions
Benzocaine 20%, Lidocaine 2%, Sham injection, Saline 0.9%
Drug · Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older · Female only
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Oct 4, 2026, 10:10 AM EDT
Recruiting Phase 2 Interventional

An Acupuncture Study for People At High Risk for Sepsis

NCT06344819
View directory record Official record
Conditions
Sepsis
Interventions
Acupuncture, Sham Acupuncture
Procedure · Other
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 4, 2026, 10:10 AM EDT
Recruiting Not applicable Interventional

Alleviant ALLAY-HFrEF Study

NCT06812533
View directory record Official record
Conditions
Heart Failure
Interventions
Alleviant ALV1 System, Sham-Control
Device · Other
Lead sponsor
Alleviant Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
40
States / cities
Los Angeles, California • Sacramento, California • San Diego, California + 31 more
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 4, 2026, 10:10 AM EDT
Recruiting Not applicable Interventional

Reducing AIR Pollution Exposure to Lower Blood PRESSURE Among New York City Public Housing Residents

NCT05874479
View directory record Official record
Conditions
Blood Pressure
Interventions
Active PAC, Sham PAC
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 100 Years
Enrollment
440 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 4, 2026, 10:10 AM EDT
Completed Phase 2 Interventional Results available

Safety and Efficacy of Brimonidine Tartrate Posterior Segment Drug Delivery System in Improving Visual Function

NCT00972374
View directory record Official record
Conditions
Rhegmatogenous Macula-off Retinal Detachment
Interventions
400 ug Brimonidine Implant, 200 ug Brimonidine Implant, Sham (no implant)
Drug · Other
Lead sponsor
Allergan
Industry
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Abilene, Texas
Source: ClinicalTrials.gov public record
Updated Apr 24, 2013 · Synced Oct 4, 2026, 10:10 AM EDT
Suspended Not applicable Interventional

The Effect of Sympathetic Modulation on Cerebral Vasospasm Secondary to Aneurysmal Subarachnoid Hemorrhage

NCT06443177
View directory record Official record
Conditions
Vasospasm, Cerebral, Aneurysmal Subarachnoid Hemorrhage
Interventions
Vectris trial leads and stimulation, Sham
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2028 – 2031
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 4, 2026, 10:10 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

The Effects of Sensory Training On Pain Modulation, Cognition and Time to Fatigue in Healthy Adults

NCT02672371
View directory record Official record
Conditions
Healthy Participants
Interventions
Active eMNS, Sham eMNS
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 40 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Oct 4, 2026, 10:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Wearable Focused Ultrasound Stimulation for Peripheral Nerve Pain Management

NCT07160049
View directory record Official record
Conditions
Pain Management, Peripheral Neuropathic Pain
Interventions
Cold Pressor Task - Upper Limb, Algometry Pain Tests in the Upper Limb, Algometry Pain Tests in the Lower Limb
Device
Lead sponsor
Evan (Huiliang) Wang
Other
Eligibility
20 Years to 40 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Oct 4, 2026, 10:10 AM EDT
Completed Phase 2 Interventional Results available

Platelet-Rich Plasma Therapy for Patellar Tendinopathy

NCT03136965
View directory record Official record
Conditions
Patellar Tendinitis
Interventions
PRP, Dry Needling, Dry Needling - Sham
Biological · Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 39 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 26, 2023 · Synced Oct 4, 2026, 10:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Priming Expectations and Motor Learning With tDCS

NCT06039605
View directory record Official record
Conditions
Expectations, Motor Learning
Interventions
Transcranial Direct Current Stimulation
Device
Lead sponsor
Arizona State University
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 4, 2026, 10:10 AM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Study of Use of Synera for Pain During Local Skin Infiltration With Lidocaine Before Epidural Placement

NCT01775605
View directory record Official record
Conditions
Pain, Anxiety
Interventions
Synera
Drug
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated May 14, 2015 · Synced Oct 4, 2026, 10:10 AM EDT
Terminated Not applicable Interventional Results available

Safety and Efficacy of EndoBarrier in Subjects With Type 2 Diabetes Who Are Obese

NCT01728116
View directory record Official record
Conditions
Type 2 Diabetes, Obesity
Interventions
EndoBarrier, Sham Procedure
Device · Procedure
Lead sponsor
Morphic Medical Inc.
Industry
Eligibility
21 Years to 65 Years
Enrollment
325 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
25
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Little Rock, Arkansas + 20 more
Source: ClinicalTrials.gov public record
Updated Feb 1, 2017 · Synced Oct 4, 2026, 10:10 AM EDT
Completed Not applicable Interventional Results available

Neuromodulation for Accidental Bowel Leakage

NCT03278613
View directory record Official record
Conditions
Fecal Incontinence, Bowel Incontinence
Interventions
ES-130
Device
Lead sponsor
NICHD Pelvic Floor Disorders Network
Network
Eligibility
18 Years and older · Female only
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
9
States / cities
Birmingham, Alabama • Downey, California • La Jolla, California + 6 more
Source: ClinicalTrials.gov public record
Updated Jun 3, 2025 · Synced Oct 4, 2026, 10:10 AM EDT
Completed Phase 1 Interventional Results available

Placebo-controlled Trial of Transdiscal Radiofrequency Annuloplasty

NCT00750191
View directory record Official record
Conditions
Lower Back Pain
Interventions
The Transdiscal Radiofrequency Annuloplasty
Device
Lead sponsor
Baylis Medical Company
Industry
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
2
States / cities
Winston-Salem, North Carolina • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 8, 2014 · Synced Oct 4, 2026, 10:10 AM EDT