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ClinicalTrials.gov public records Last synced Nov 15, 2026, 7:25 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 73–96 of 147 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sham Air Clear all

Conditions: Fibromyalgia, Central Neuropathic Pain
Interventions: Nitrous oxide gas for inhalation, Placebo; Drug
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years to 75 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Asthma
Interventions: integrated pest management, air purifier, Sham air purifier; Other
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 4 Years to 15 Years
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Pollution; Exposure, Smoke Inhalation, Exposure to Pollution
Interventions: Cigarette Smoke, Clean Air and Clean Clothing/Sham exposure; Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 50 Years
Enrollment: 66 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Spinal Cord Injuries
Interventions: Repeated exposure to acute Intermittent Hypoxia (rAIH), Normal Room Air, Upper-limb Training by Research Staff, Lower-limb Training by Research Staff; Other
Lead sponsor: Shirley Ryan AbilityLab; Other
Eligibility: 18 Years to 85 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Asthma, Allergic Rhinitis, Allergic Conjunctivitis
Interventions: Active air purifier in respiratory allergies/asthma, Sham air purifier; Other
Lead sponsor: Molekule; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 49 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Persistent Post-concussive Syndrome, Concussion Post Syndrome
Interventions: Hyperbaric oxygen at 1.5 ATA, Sham treatment; Drug
Lead sponsor: Essentia Health; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Fargo, North Dakota

Conditions: Mild Traumatic Brain Injury, Post-Concussive Syndrome
Interventions: Hyperbaric Oxygen Therapy; Procedure
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 19 Years to 60 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 3
States / cities: Portsmouth, Virginia • Richmond, Virginia

Conditions: Aging
Interventions: Acute Intermittent Hypoxia, Computerized Cognitive Training; Device · Behavioral
Lead sponsor: University of Florida; Other
Eligibility: 65 Years to 89 Years
Enrollment: 11 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Diabetes Mellitus
Interventions: HBOT intervention, Sham intervention; Device
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 65 Years and older
Enrollment: 155 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2024
U.S. locations: 2
States / cities: New York, New York • Madison, Wisconsin

Conditions: Radiation Injuries
Interventions: Hyperbaric Oxygen Therapy, Sham treatment; Procedure
Lead sponsor: National Baromedical Services; Other
Eligibility: Not listed
Enrollment: 248 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2015
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: Traumatic Brain Injury
Interventions: Repetitive Transcranial Magnetic Stimulation; Device
Lead sponsor: University of New Mexico; Other
Eligibility: 18 Years to 55 Years
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Stroke
Interventions: Single-pulse Transcranial Magnetic Stimulation (TMS), Paired-pulse Transcranial Magnetic Stimulation (ppTMS), Low-frequency Repetitive Transcranial Magnetic Stimulation (rTMS), Sham Motor Cortex Stimulation; Device
Lead sponsor: Emory University; Other
Eligibility: 40 Years to 80 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2021
U.S. locations: 3
States / cities: Atlanta, Georgia

Conditions: Peripheral Artery Disease
Interventions: intermittent pneumatic compression, exercise, Sham device, Health Education; Device · Behavioral
Lead sponsor: Northwestern University; Other
Eligibility: 55 Years and older
Enrollment: 211 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2026
U.S. locations: 4
States / cities: Chicago, Illinois • Detroit, Michigan • Minneapolis, Minnesota

Conditions: Venous Leg Ulcer (VLU)
Interventions: Topical Wound Oxygen Therapy, Sham Control Topical Wound Oxygen; Device
Lead sponsor: AOTI Ltd.; Industry
Eligibility: 18 Years and older
Enrollment: 212 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: New York, New York

Conditions: Sleep-disordered Breathing, Chronic Opioid Use
Interventions: Sham Air, Supplemental Oxygen; Other · Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 75 Years
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Down Syndrome, Obstructive Sleep Apnea Syndrome
Interventions: Continuous positive airway pressure, Sham or placebo continuous positive airway pressure; Device
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 8 Years to 20 Years
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Mild Cognitive Impairment, Memory Impairment
Interventions: IHT Treatment, Sham-IHT Control; Device · Other
Lead sponsor: University of North Texas Health Science Center; Other
Eligibility: 55 Years to 79 Years
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Fort Worth, Texas

Conditions: Asthma
Interventions: Stand Alone Air Cleaner, HVAC Modification; Other
Lead sponsor: University of California, Davis; Other
Eligibility: 6 Years to 12 Years
Enrollment: 219 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: Davis, California

Conditions: Cannabis Use, Cannabis Use Disorder
Interventions: Magstim SuperRapid2, Sham rTMS; Device
Lead sponsor: University of Minnesota; Other
Eligibility: 15 Years to 21 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2029
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: TBI Depression
Interventions: Low Frequency Right sided repetitive transcranial magnetic stimulation (LFR rTMS), Sham Comparator: Sham Treatment; Combination Product · Device
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Pediatric Asthma
Interventions: Portable air cleaner with HEPA filter, Less effective portable air cleaner (no HEPA); Device
Lead sponsor: University of Washington; Other
Eligibility: 6 Years to 12 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Sleep Apnea, Obstructive
Interventions: soft palate implant, Positive airway pressure (PAP); Device · Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 80 Years
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Migraine, Episodic Migraine, Migraine With Aura, Migraine Without Aura
Interventions: CoolStat active device, CoolStat sham device; Device
Lead sponsor: CoolTech LLC; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 3
States / cities: Scottsdale, Arizona • East Lansing, Michigan • Charlotte, North Carolina

Conditions: Asthma
Interventions: integrated pest management, air purifier, No intervention (control); Other
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 4 Years to 15 Years
Enrollment: 236 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Boston, Massachusetts

Search by objective public record fields.

Nitrous Oxide as Treatment for Fibromyalgia

Environmental Intervention to Reduce Allergens in Urban Schools and Childhood Asthma

Controlled Exposure of Healthy Nonsmokers to Secondhand and Thirdhand Cigarette Smoke

Repetitive Acute Intermittent Hypoxia for Spinal Cord Repair

Molekule for Allergic Rhinitis/Asthma

Hyperbaric Oxygen Effects on Persistent Post-concussive Symptoms

Hyperbaric Oxygen Therapy (HBO2T) for Post-Concussive Symptoms (PSC) After Mild Traumatic Brain Injury (mTBI)

Enhancing Cognition in Older Adults With Intermittent Hypoxia and Cognitive Training

Hyperbaric Oxygen Therapy for Cognition in Diabetic Elderly at High Dementia Risk

Study to Determine if Hyperbaric Oxygen Therapy is Helpful for Treating Radiation Tissue Injuries

Noninvasive Modulation of Motivational Brain Regions in Healthy Volunteers

Customized Cortical Stimulation Therapy in the Rehabilitation of Stroke Patients

Intermittent Pneumatic Compression With and Without Exercise to Improve Functioning in Peripheral Artery Disease

Trial to Evaluate Cyclical Topical Wound Oxygen Therapy in the Treatment of Chronic Venous Leg Ulcers

Supplemental Oxygen for Sleep-Disordered Breathing in Adults With Chronic Opioid Use.

Obstructive Sleep Apnea and Neurocognitive and Cardiovascular Function in Children With Down Syndrome

IHT for Mild Cognitive Impairment

Asthma and Indoor-air: Reducing Exposures

Transcranial Magnetic Stimulation for Adolescents and Young Adults With Cannabis Use Disorder

Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Depression & Other Neuropsychiatric Symptoms After Traumatic Brain Injury (TBI)

The Airports, Air Quality, and Asthma (AAA) Study

Treatment Study of Soft Palatal Implants in Obstructive Sleep Apnea

Transnasal Cooling for Migraine

School Inner-City Asthma Intervention Study (SICAS-2)