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ClinicalTrials.gov public records Last synced Nov 15, 2026, 7:39 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 121–144 of 147 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sham Air Clear all

Conditions: Acute Hypoxemic Respiratory Failure
Interventions: Lucinactant, Sham Comparator; Drug · Other
Lead sponsor: Windtree Therapeutics; Industry
Eligibility: Up to 2 Years
Enrollment: 165 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Warrington, Pennsylvania

Conditions: Spinal Cord Injuries
Interventions: Acute Intermittent Hypoxia, Sham Acute Intermittent Hypoxia; Other
Lead sponsor: Shirley Ryan AbilityLab; Other
Eligibility: 18 Years to 70 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Adverse Effect of Other Agents Primarily Affecting the Cardiovascular System, Initial Encounter
Interventions: Cigarette, NIDA test type with 16.6 mg nicotine, Cigarette, NIDA test type with <0.45 mg nicotine, Electronic cigarette with 18 mg/ml nicotine, Electronic Cigarette with no nicotine, Moist snuff, Sham Smoking, Secondhand cigarette smoke (SHS), Conditioned, filtered air, Sham Moist Snuff; Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 50 Years
Enrollment: 81 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2021
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Plantar Fasciitis
Interventions: Duolith SD1, Sham Duolith SD1; Device
Lead sponsor: Storz Medical AG; Industry
Eligibility: 18 Years and older
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2006
U.S. locations: 6
States / cities: Palo Alto, California • Hamden, Connecticut • Newtown, Connecticut + 3 more

Conditions: Opioid Use Disorder, Moderate, Opioid Use Disorder, Severe, Withdrawal Symptoms, Craving, Negative Affectivity
Interventions: CBOT + TAU, Sham + TAU; Drug
Lead sponsor: Evon Medics LLC; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 190 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 4
States / cities: Washington D.C., District of Columbia • Rockville, Maryland

Conditions: Spinal Cord Injuries
Interventions: AIH - Intermittent Hypoxia - hypoxia air mixture, SHAM - Intermittent Room Air - room air mixture, TESS - Transcutaneous Electrical Spinal Cord Stimulation + Functional Task Practice; Other · Device
Lead sponsor: Spaulding Rehabilitation Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Cambridge, Massachusetts

Conditions: Asthma
Interventions: Bronchial Thermoplasty; Other
Lead sponsor: Boston Scientific Corporation; Industry
Eligibility: Not listed
Enrollment: 192 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 6
States / cities: Los Angeles, California • Detroit, Michigan • Saint Paul, Minnesota + 3 more

Conditions: Obstructive Sleep Apnea
Interventions: Respiratory muscle strength training, Sham respiratory muscle strength training; Device
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 80 Years
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Spinal Cord Injuries
Interventions: SHAM - Intermittent Room Air - room air mixture, AIH - Intermittent Hypoxia - hypoxia air mixture; Other
Lead sponsor: Spaulding Rehabilitation Hospital; Other
Eligibility: 18 Years to 75 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2027
U.S. locations: 1
States / cities: Cambridge, Massachusetts

Conditions: Post-concussive Symptoms, Traumatic Brain Injury
Interventions: hyperbaric oxygen, sham hyperbaric air; Drug · Other
Lead sponsor: U.S. Army Medical Research and Development Command; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 79 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 5
States / cities: Camp Pendleton, California • Fort Carson, Colorado • Fort Gordon, Georgia + 2 more

Conditions: Sepsis
Interventions: Bilateral phrenic nerve stimulation and measurement of transdiaphragmatic pressure, Midazolam, Volitional Measurement of Maximal Inspiratory Pressure (MIP), Inspiratory Muscle Strength Training (IMST), SHAM Inspiratory Muscle Strength Training (IMST), Diaphragm thickness measurement, Blood and Urine samples; Procedure · Drug · Device + 1 more
Lead sponsor: University of Florida; Other
Eligibility: 18 Years and older
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting, Multiple Sclerosis, Secondary Progressive
Interventions: Acute Intermittent Hypoxia, Sham Acute Intermittent Hypoxia; Other
Lead sponsor: Shirley Ryan AbilityLab; Other
Eligibility: 18 Years to 75 Years
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Spinal Cord Injury
Interventions: Acute Intermittent Hypoxia (AIH), SHAM-Intermittent Room Air; Drug · Other
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 53 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Prosthesis-Related Infections
Interventions: ABS deployed and active, ABS deployed and NOT active; Device
Lead sponsor: Nimbic Systems, LLC; Industry
Eligibility: 21 Years and older
Enrollment: 816 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Spinal Cord Injuries
Interventions: Acute Intermittent Hypoxia (AIH), Upper extremity training, Sham Acute intermittent hypoxia; Other · Behavioral
Lead sponsor: Shirley Ryan AbilityLab; Other
Eligibility: 18 Years to 70 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Cardiac Arrest
Interventions: Active Remote Ischemic Conditioning, Sham Remote Ischemic Conditioning; Device
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Cardiovascular Diseases
Interventions: Portable air cleaner (PAC), Sham Portable air cleaner (PAC); Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 100 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Respiratory Distress Syndrome, Newborn, Premature Birth, Bronchopulmonary Dysplasia
Interventions: Lucinactant 175 mg/kg, Lucinactant 90 mg/kg, Placebo; Drug
Lead sponsor: Windtree Therapeutics; Industry
Eligibility: 3 Days to 10 Days
Enrollment: 136 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2006
U.S. locations: 1
States / cities: Warrington, Pennsylvania

Conditions: Cognitive Impairment, Traumatic Brain Injury
Interventions: repetitive Transcranial Magnetic Stimulation; Device
Lead sponsor: Hunter Holmes Mcguire Veteran Affairs Medical Center; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Obstructive Sleep Apnea
Interventions: Mild Intermittent Hypoxia, Sham MIH; Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 30 Years to 60 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Fecal Incontinence
Interventions: Translumbosacral Neuromodulation Therapy (TNT), Sham TNT Therapy; Device · Other
Lead sponsor: Augusta University; Other
Eligibility: 18 Years and older
Enrollment: 132 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 2
States / cities: Augusta, Georgia • Boston, Massachusetts

Conditions: Chronic Cough, OSA
Interventions: Straight CPAP, Sham CPAP; Device
Lead sponsor: Krishna M. Sundar; Other
Eligibility: 18 Years to 80 Years
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Air Pollution, Cardiometabolic Health
Interventions: HEPA filter, Sham filter; Device
Lead sponsor: University of Southern California; Other
Eligibility: 65 Years to 84 Years
Enrollment: 52 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Obstructive Sleep Apnea
Interventions: PAP therapy, Sham PAP therapy; Device
Lead sponsor: University of Tennessee; Other
Eligibility: 6 Years to 12 Years
Enrollment: 79 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2016
U.S. locations: 1
States / cities: Memphis, Tennessee

Search by objective public record fields.

Lucinactant for Treatment of Acute Hypoxemic Respiratory Failure in Children up to Two Years Old

Timing and Dosage of Acute Intermittent Hypoxia in Persons With SCI

Cardiovascular Assessment of the Effects of Tobacco and Nicotine Delivery Products

Study of Effectiveness and Safety of Extracorporeal Shock Wave Therapy (ESWT) for Treatment of Painful Heel Syndrome

Computerized Chemosensory-Based Orbitofrontal Cortex (CBOT) for Opioid Use Disorder

Pairing Intermittent Hypoxia and Transcutaneous Electrical Spinal Cord Stimulation to Promote Arm Use After Cervical SCI

Bronchial Thermoplasty 10+ Year Study

Airway Muscle Training for Obstructive Sleep Apnea

Acute Intermittent Hypoxia on Leg Function Following Spinal Cord Injury

Hyperbaric Oxygen Therapy (HBO2) for Persistent Post-concussive Symptoms After Mild Traumatic Brain Injury (mTBI)

Project 4A: Inspiratory Muscle Training and Diaphragm Strength

Effects of Acute Intermittent Hypoxia on Neuroplasticity in MS

Study Effects of Intermittent Hypoxia on Restoring Hand Function Following SCI

Air Barrier System for the Prevention of Prosthesis-related Infections

Daily Intermittent Hypoxia and Task-Specific Upper Limb Training in Persons With Chronic Incomplete SCI

Remote Ischemic Conditioning to Enhance Resuscitation (RICE) Pilot

Cleaner Air for Better Cardiac Biomarkers

SURFAXIN® Treatment for Prevention of Bronchopulmonary Dysplasia (BPD) in Very Low Birth Weight (VLBW) Infants.

rTMS for Cognitive Rehabilitation After TBI

Intermittent Hypoxia-initiated Plasticity in Humans: A Multi-pronged Therapeutic Approach to Treat Sleep Apnea and Overlapping Co-morbidities

Translumbosacral Neuromodulation for FI

Sham CPAP vs. Straight CPAP for Chronic Cough

HEPA, PM2.5, and Cardiometabolic Health

Effects of Positive Airway Pressure (PAP) in Children With Obstructive Sleep Apnea (OSA)