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Showing 1–24 of 36 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Sham Biofeedback Clear all
Recruiting Not applicable Interventional

MINT Conditioning to Improve Gait

NCT07041775
View directory record Official record
Conditions
Stroke, Stroke Gait Rehabilitation
Interventions
myoelectric interface for neurorehabilitation (MINT) conditioning, One muscle myoelectric feedback
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 85 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
2
States / cities
Chicago, Illinois • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Sep 2, 2026, 10:31 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Multiple Component Mobile-aid Pain Reduction Intervention to Decrease Myofascial Pain

NCT05860205
View directory record Official record
Conditions
Myofascial Pain Syndrome
Interventions
Multiple Component Mobile-Aid Pain Reduction Intervention, Osteopathic Manipulation Treatment, Sham Osteopathic Manipulation
Behavioral · Other
Lead sponsor
Kailea Manning
Other
Eligibility
18 Years to 64 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
2
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated May 15, 2023 · Synced Sep 2, 2026, 10:31 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mobile Neurofeedback for Low Back Pain

NCT05669027
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Neurofeedback, Sham (Placebo Control)
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 90 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Sep 2, 2026, 10:31 PM EDT
Terminated Not applicable Interventional

Randomized Controlled Trial of Biofeedback Therapy for Dyssynergic Defecation

NCT00257842
View directory record Official record
Conditions
Dyssynergia
Interventions
Standard treatment, sham feedback and biofeedback therapy
Procedure
Lead sponsor
Augusta University
Other
Eligibility
15 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 16, 2014 · Synced Sep 2, 2026, 10:31 PM EDT
Recruiting Not applicable Interventional

Mechanistic Study of Inspiratory Training in Childhood Asthma (MICA)

NCT05945355
View directory record Official record
Conditions
Asthma in Children, Obesity, Pediatric Obesity, Pediatric Asthma
Interventions
Pro2 - Low Dose - 40% of participant's MIP, Pro2 - High Dose - 75% of participant's MIP, Pro2 - SHAM - 15% of participant's MIP
Device
Lead sponsor
Duke University
Other
Eligibility
6 Years to 17 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 2, 2026, 10:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Psychophysiologic Predictors of Post-deployment Mental Health Outcomes

NCT00838006
View directory record Official record
Conditions
Post-traumatic Stress Disorder
Interventions
heart rate variability biofeedback, Cognitive bias modification training, Sham Comparator
Device
Lead sponsor
Biomedical Research Foundation
Other
Eligibility
18 Years to 60 Years
Enrollment
426 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Blackstone, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 1, 2020 · Synced Sep 2, 2026, 10:31 PM EDT
Enrolling by invitation Not applicable Interventional

App-based Breathing Program for Migraine Relief

NCT07297901
View directory record Official record
Conditions
Migraine, Heart Rate Variability (HRV), Autonomic Nervous System, Headache (Migraine), Headache, Chronic Pain, mHealth, Breathing
Interventions
Baseline Survey, Heart rate variability biofeedback, Sham Control Group
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Sep 2, 2026, 10:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

An Evaluation of Neurofeedback Efficacy in Adults With ADHD

NCT01852357
View directory record Official record
Conditions
ADHD
Interventions
Neurofeedback, Sham Neurofeedback
Other
Lead sponsor
University of North Carolina, Wilmington
Other
Eligibility
18 Years to 40 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Wilmington, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 25, 2016 · Synced Sep 2, 2026, 10:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Real-time Sensorimotor Feedback for Injury Prevention Assessed in Virtual Reality

NCT02933008
View directory record Official record
Conditions
Injury of Anterior Cruciate Ligament
Interventions
aNMT Biofeedback, Sham Biofeedback, Neuromuscular Training
Other
Lead sponsor
Emory University
Other
Eligibility
12 Years to 18 Years · Female only
Enrollment
420 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
2
States / cities
Flowery Branch, Georgia • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 2, 2026, 10:31 PM EDT
Recruiting Not applicable Interventional

A Study of a Novel EEG Neurofeedback System for PTSD Treatment

NCT06770998
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
EEG-neurofeedback training, Sham training
Device
Lead sponsor
Foundation for Atlanta Veterans Education and Research, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
6
States / cities
Birmingham, Alabama • Decatur, Georgia • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Sep 2, 2026, 10:31 PM EDT
Not listed Not applicable Interventional

Inspiratory Muscle Training in COPD

NCT03438019
View directory record Official record
Conditions
COPD
Interventions
PrO2, Threshold Inspiratory Muscle Trainer
Device
Lead sponsor
Miami VA Healthcare System
Federal
Eligibility
40 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jul 19, 2018 · Synced Sep 2, 2026, 10:31 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Using Heart Rate Variability Biofeedback to Improve Attention and Memory in PTSD+ Combat Veterans

NCT00625105
View directory record Official record
Conditions
PTSD
Interventions
Biofeedback
Behavioral
Lead sponsor
William Jennings Bryan Dorn VA Medical Center
Federal
Eligibility
20 Years to 40 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 6, 2014 · Synced Sep 2, 2026, 10:31 PM EDT
Recruiting Not applicable Interventional

Inspiratory Pulmonary Rehabilitation for Children With Obesity and Asthma

NCT05608668
View directory record Official record
Conditions
Pediatric Obesity, Pediatric Asthma
Interventions
Pro2 - 60% of participant's MIP, Pro2 - 15% of participant's MIP
Device
Lead sponsor
Duke University
Other
Eligibility
8 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Sep 2, 2026, 10:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Acute Effects of an Isometric Loading Intervention on Lower Extremity Landing Biomechanics in Individuals With Patellar Tendinopathy

NCT03262181
View directory record Official record
Conditions
Tendinopathy
Interventions
Isometric Exercise, Sham Transcutaneous Electrical Nerve Stimulation
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
15 Years to 28 Years · Male only
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 18, 2019 · Synced Sep 2, 2026, 10:31 PM EDT
Completed Not applicable Interventional Results available

High-resolution, Relational, Resonance-based, Electroencephalic Mirroring (HIRREM) to Relieve Insomnia

NCT01971567
View directory record Official record
Conditions
Insomnia
Interventions
HIRREM
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 9, 2018 · Synced Sep 2, 2026, 10:31 PM EDT
Completed Not applicable Interventional Results available

Virtual Reality Therapy for Chronic Low Back Pain

NCT04409353
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Distraction-Based VR, Sham VR, Skills-Based VR, Activity Tracker
Device
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
13 Years and older
Enrollment
413 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Sep 2, 2026, 10:31 PM EDT
Completed Not applicable Interventional

Optimizing Gait Biomechanics for Posttraumatic Osteoarthritis Prevention

NCT05007366
View directory record Official record
Conditions
Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, Knee Osteoarthritis, Knee Injuries, Cartilage, Articular, Gait
Interventions
Real-time gait biofeedback, Sham real-time gait biofeedback
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 35 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 17, 2023 · Synced Sep 2, 2026, 10:31 PM EDT
Recruiting Not applicable Interventional

Gait Rehabilitation to Treat FastOA

NCT05848622
View directory record Official record
Conditions
Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, Knee Osteoarthritis, Osteo Arthritis Knee, Knee Injuries, Cartilage, Articular, Gait
Interventions
Real-time gait biofeedback, Sham real-time gait biofeedback
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
16 Years to 35 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Sep 2, 2026, 10:31 PM EDT
Completed Not applicable Interventional Results available

EEG Biofeedback Therapy as an Adjunct Treatment for PTSD

NCT01591408
View directory record Official record
Conditions
PTSD, Anxiety, Trauma, Sleep Disorders
Interventions
EEG biofeedback
Device
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years to 40 Years · Male only
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 19, 2016 · Synced Sep 2, 2026, 10:31 PM EDT
Completed Not applicable Interventional Results available

Inspiratory Muscle Rehabilitation in Children With Obesity

NCT05412134
View directory record Official record
Conditions
Pediatric Obesity
Interventions
Pro2 - 75% of participant's MIP, Pro2 - 15% of participant's MIP
Device
Lead sponsor
Duke University
Other
Eligibility
8 Years to 17 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 17, 2024 · Synced Sep 2, 2026, 10:31 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Self-activation in Individuals With and Without Nicotine Dependence

NCT03170258
View directory record Official record
Conditions
Addiction Nicotine
Interventions
Neurofeedback (from fMRI and/or EEG)
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 45 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 4, 2024 · Synced Sep 2, 2026, 10:31 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Visible Abdominal Distension

NCT06369753
View directory record Official record
Conditions
Irritable Bowel Syndrome, Dyspepsia, Functional Bloating
Interventions
Biofeedback, Placebo
Behavioral
Lead sponsor
Hospital Universitari Vall d'Hebron Research Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Sep 2, 2026, 10:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

EEG Alpha/Theta Neurofeedback to Reduce Trait Anxiety

NCT02964520
View directory record Official record
Conditions
Anxiety
Interventions
Neurofeedback training, Sham comparator: Sham neurofeedback training
Behavioral
Lead sponsor
University of Hartford
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
West Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 4, 2017 · Synced Sep 2, 2026, 10:31 PM EDT
Completed Not applicable Interventional Results available

Pilot Feasibility Study of Neurofeedback for Attention Deficit Hyperactivity Disorder (ADHD)

NCT00886483
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder
Interventions
Active Neurofeedback, Sham neurofeedback
Device
Lead sponsor
L. Eugene Arnold
Other
Eligibility
6 Years to 12 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 10, 2016 · Synced Sep 2, 2026, 10:31 PM EDT