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ClinicalTrials.gov public records Last synced Oct 17, 2026, 10:30 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 1,011 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Sham Condition Clear all
Terminated Not applicable Interventional Results available

Neural and Behavioral Effects of Cognitive Bias Modification (CBM)

NCT04430543
View directory record Official record
Conditions
Alcohol Drinking
Interventions
Cognitive Bias Modification, Sham Training
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years to 34 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 17, 2026, 10:30 PM EDT
Completed Not applicable Interventional Results available

Clinical and Microbiologic Outcomes of Adjunctive Antimicrobial Photodynamic Therapy in the Non-surgical and Surgical Treatment of Teeth With Periodontal Disease

NCT05252000
View directory record Official record
Conditions
Periodontal Diseases
Interventions
mechanical debridement, adjunctive aPDT, sham aPDT
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Oct 17, 2026, 10:30 PM EDT
Terminated Phase 3 Interventional Results available

A Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 in Non-proliferative Diabetic Retinopathy (NPDR)

NCT05066230
View directory record Official record
Conditions
Non-proliferative Diabetic Retinopathy
Interventions
KSI-301, Sham injection
Drug · Other
Lead sponsor
Kodiak Sciences Inc
Industry
Eligibility
18 Years and older
Enrollment
253 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
46
States / cities
Phoenix, Arizona • Beverly Hills, California • Fullerton, California + 42 more
Source: ClinicalTrials.gov public record
Updated Sep 5, 2024 · Synced Oct 17, 2026, 10:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Development of Non-Invasive Brain Stimulation Techniques

NCT03351764
View directory record Official record
Conditions
Normal Physiology
Interventions
Sham TMS, TMS
Device
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 65 Years
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 17, 2026, 10:30 PM EDT
Completed Not applicable Interventional Results available

Empower: tDCS for Major Depressive Disorder at Home

NCT05202119
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Transcranial direct current stimulation, Sham Transcranial direct current stimulation
Device
Lead sponsor
Flow Neuroscience AB
Industry
Eligibility
18 Years and older
Enrollment
174 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Oct 17, 2026, 10:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise and Transcranial Magnetic Stimulation: Increasing Brain Plasticity in Parkinson's Disease

NCT02741765
View directory record Official record
Conditions
Parkinson Disease
Interventions
Sham rTMS, Real rTMS, Supervised aerobic exercise
Behavioral · Other
Lead sponsor
NYU Langone Health
Other
Eligibility
35 Years to 85 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 16, 2019 · Synced Oct 17, 2026, 10:30 PM EDT
Completed Phase 2 Interventional Results available

Dextroamphetamine and tDCS to Improve the Fluency

NCT02514044
View directory record Official record
Conditions
Stroke
Interventions
Dexedrine, Active tDCS, Speech Therapy, Placebo, Sham tDCS
Drug · Device · Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 3, 2018 · Synced Oct 17, 2026, 10:30 PM EDT
Completed Not applicable Interventional Results available

STimulation to Improve Auditory haLLucinations

NCT02360228
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder
Interventions
tACS (alpha), tDCS
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 27, 2018 · Synced Oct 17, 2026, 10:30 PM EDT
Recruiting Not applicable Interventional

Personalized Ultrasonic Brain Stimulation for Fibromyalgia

NCT07361328
View directory record Official record
Conditions
Fibromyalgia (FM)
Interventions
Low-intensity ultrasound brain stimulation, Sham (No Treatment)
Device
Lead sponsor
University of Utah
Other
Eligibility
22 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 23, 2026 · Synced Oct 17, 2026, 10:30 PM EDT
Not listed Phase 2 Interventional

Development and Evaluation of Computerized Olfactory Training Program for Cognitive Decline in Early Alzheimer's Disease

NCT05122598
View directory record Official record
Conditions
Mild Cognitive Impairment, Early Alzheimer's Disease, Memory Impairment
Interventions
COT, Sham
Drug
Lead sponsor
Evon Medics LLC
Industry
Eligibility
55 Years to 95 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
3
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated May 17, 2022 · Synced Oct 17, 2026, 10:30 PM EDT
Completed Not applicable Interventional

NightWare Randomized Trial 02

NCT04040387
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Combat Disorders, Ptsd, Nightmare, Nightmares, REM-Sleep Type, Nightmare Disorder With Associated Non-Sleep Disorder
Interventions
NightWare Therapeutic System, Sham NightWare
Device
Lead sponsor
NightWare
Industry
Eligibility
22 Years and older
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
4
States / cities
Bethesda, Maryland • Minneapolis, Minnesota • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 17, 2026, 10:30 PM EDT
Active, not recruiting Not applicable Interventional

Accelerated Intermittent Theta-Burst Stimulation (aiTBS) in Treatment-Resistant Depression of Bipolar II Disorder

NCT05849402
View directory record Official record
Conditions
Bipolar II Disorder, Most Recent Episode Major Depressive, Current Depressive Episode, Treatment Resistant Depression
Interventions
Active Comparator: Active aiTBS, Sham Comparator: Sham aiTBS
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 17, 2026, 10:30 PM EDT
Terminated Not applicable Interventional

One Needle Hand Acupuncture for MSK Disorders

NCT04048941
View directory record Official record
Conditions
Acupuncture, Pain, Range of Motion
Interventions
One Needle Hand Acupuncture with Movement, One Needle Hand Acupuncture without Movement, Control Acupuncture with Movement
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 99 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Chesterfield, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 17, 2026, 10:30 PM EDT
Completed Not applicable Interventional Results available

Singing and Cardiovascular Health in Older Adults

NCT04121741
View directory record Official record
Conditions
Cardiovascular Diseases, Cardiovascular Risk Factor, Cardiovascular Health
Interventions
Singing with Music Therapist, Singing with Guided Video, Control Arm
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
55 Years to 79 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Oct 17, 2026, 10:30 PM EDT
Completed Not applicable Interventional Results available

Transcranial Magnetic Stimulation for the Treatment of Veterans With Alcohol Use Disorders

NCT03191266
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Active rTMS, Sham rTMS
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Oct 17, 2026, 10:30 PM EDT
Completed Phase 2 Interventional Results available

Masked Faces in Parkinson Disease: Mechanism and Treatment

NCT00350402
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Respiratory muscle strength training
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
45 Years to 80 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 6, 2012 · Synced Oct 17, 2026, 10:30 PM EDT
Terminated Phase 3 Interventional Results available

Bevacizumab in Treating Patients With Metastatic Breast Cancer That Overexpresses HER-2/NEU

NCT00520975
View directory record Official record
Conditions
Breast Carcinoma, Recurrent Breast Carcinoma, Stage IV Breast Cancer
Interventions
Bevacizumab, Carboplatin, Paclitaxel, Placebo, Trastuzumab
Biological · Drug · Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2015
U.S. locations
373
States / cities
Jonesboro, Arkansas • Castro Valley, California • Emeryville, California + 236 more
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 17, 2026, 10:30 PM EDT
Recruiting Phase 1 Interventional

Autologous suraL nervE Grafting to the Substantia nigrA in Patients With Synuclienopathies

NCT06683365
View directory record Official record
Conditions
Multiple System Atrophy, Parkinsons Disease
Interventions
Sural Nerve Graft to the Substantia Nigra, Sham surgery
Procedure
Lead sponsor
Craig van Horne, MD, PhD
Other
Eligibility
40 Years to 75 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Oct 17, 2026, 10:30 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Alpha Auditory Entrainment for Cognitive Enhancement and Sensory Hypersensitivity in Youth With Developmental Disorders

NCT06227780
View directory record Official record
Conditions
Fragile X Syndrome, Autism Spectrum Disorder, Autistic Disorder, Asperger Syndrome
Interventions
Alpha Auditory Entrainment, Sham
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
5 Years to 10 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 17, 2026, 10:30 PM EDT
Withdrawn Not applicable Interventional

A Study to Evaluate the Role of Alternative Medicine in Difficult to Treat GERD Patients

NCT00591877
View directory record Official record
Conditions
Gastroesophageal Reflux Disease
Interventions
Acupuncture, Sham Acupuncture, Yoga
Procedure · Other
Lead sponsor
Midwest Biomedical Research
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 26, 2012 · Synced Oct 17, 2026, 10:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sustaining Aviator Performance During Extended Operational Flight

NCT04697901
View directory record Official record
Conditions
Transcranial Direct Current Stimulation
Interventions
Active Transcranial Direct Current Stimulation (tDCS), Sham Transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
United States Army Aeromedical Research Laboratory
Federal
Eligibility
18 Years to 40 Years · Male only
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Fort Rucker, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 25, 2022 · Synced Oct 17, 2026, 10:30 PM EDT
Completed Not applicable Interventional

Impact of Neuromodulation on Language Impairments in Stroke Patients

NCT03699930
View directory record Official record
Conditions
Stroke, Aphasia
Interventions
tDCS, Speech and language therapy
Device · Behavioral
Lead sponsor
Casa Colina Hospital and Centers for Healthcare
Other
Eligibility
18 Years to 85 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Pomona, California
Source: ClinicalTrials.gov public record
Updated Jul 7, 2023 · Synced Oct 17, 2026, 10:30 PM EDT
Terminated Not applicable Interventional

Use of tAN® in Alcohol Withdrawal Management

NCT06771037
View directory record Official record
Conditions
Alcohol Withdrawal
Interventions
Transcutaneous Auricular Neurostimulation (tAN)
Device
Lead sponsor
Erin Takemoto
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Wernersville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 17, 2026, 10:30 PM EDT
Not yet recruiting Not applicable Interventional

Battlefield Acupressure for Acute Back Pain Management in the Emergency Department

NCT07771686
View directory record Official record
Conditions
Acute Back Pain
Interventions
Battlefield auricular acupressure, Sham
Procedure
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 17, 2026, 10:30 PM EDT