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ClinicalTrials.gov public records Last synced Oct 19, 2026, 1:04 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 625–648 of 1,011 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Sham Condition Clear all
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Development of Adaptive Deep Brain Stimulation for OCD

NCT04281134
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Summit RC+S System, One Month Blinded Discontinuation Period:
Device · Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
21 Years to 70 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
3
States / cities
Pittsburgh, Pennsylvania • Providence, Rhode Island • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Oct 19, 2026, 1:04 PM EDT
Active, not recruiting Not applicable Interventional

ExAblate Pallidotomy for Medically-Refractory Dyskinesia Symptoms or Motor Fluctuations of Advanced Parkinson's Disease

NCT03319485
View directory record Official record
Conditions
Parkinson Disease
Interventions
ExAblate Pallidotomy, Sham ExAblate Pallidotomy
Device
Lead sponsor
InSightec
Industry
Eligibility
30 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
11
States / cities
Stanford, California • Boynton Beach, Florida • Baltimore, Maryland + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 20, 2026 · Synced Oct 19, 2026, 1:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Treating Cancer-Related Fatigue Through Systematic Light Exposure (Light for Fatigue Study)

NCT03119363
View directory record Official record
Conditions
Multiple Myeloma, Fatigue
Interventions
AYO light glasses (Experimental), AYO light glasses (Comparator)
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
194 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2022
U.S. locations
3
States / cities
Hackensack, New Jersey • New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 16, 2022 · Synced Oct 19, 2026, 1:04 PM EDT
Completed Not applicable Interventional Results available

Transcranial Magnetic Stimulation in Spino-Cerebellar Ataxia

NCT01975909
View directory record Official record
Conditions
Spinocerebellar Ataxia
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 30, 2017 · Synced Oct 19, 2026, 1:04 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Theta-Burst Stimulation as a Treatment for Reducing Cocaine Use

NCT02927236
View directory record Official record
Conditions
Cocaine Use Disorder, Cocaine Dependence
Interventions
Transcranial magnetic stimulation (TMS)
Device
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
22 Years to 60 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 25, 2025 · Synced Oct 19, 2026, 1:04 PM EDT
Recruiting Not applicable Interventional

Clinical Trial Evaluating the Safety and Efficacy of Nucleus Pulposus Allograft in Participants With Degenerative Disc Disease

NCT06778447
View directory record Official record
Conditions
Degenerative Disc Disease, Disc Degeneration, Lumbar Discogenic Pain
Interventions
VIA Disc NP, Sham
Other
Lead sponsor
VIVEX Biologics, Inc.
Industry
Eligibility
22 Years to 85 Years
Enrollment
325 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
19
States / cities
Napa, California • Santa Monica, California • Thornton, Colorado + 16 more
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 19, 2026, 1:04 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Temporal Interference Methods for Addiction Treatment

NCT07210268
View directory record Official record
Conditions
Nicotine Use Disorder, Substance Use Disorders
Interventions
TI-NDBS, Sham TI-NDBS
Device
Lead sponsor
Indiana University
Other
Eligibility
21 Years to 50 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Bloomington, Indiana • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 19, 2026, 1:04 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Solving Stigma Through POV Simulation: Enhancing Pharmacist Empathy-based Practices With Sickle Cell Disease Patients

NCT07217548
View directory record Official record
Conditions
Stigma
Interventions
point of view simulation, Control
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 19, 2026, 1:04 PM EDT
Not listed Not applicable Interventional

Augmenting Treatment Effects of Voice Therapy in Parkinson Disease

NCT02265315
View directory record Official record
Conditions
Parkinson Disease
Interventions
Transcranial Magnetic Stimulation, Lee Silverman Voice Treatment
Other · Behavioral
Lead sponsor
Le Bonheur Children's Hospital
Other
Eligibility
45 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 22, 2020 · Synced Oct 19, 2026, 1:04 PM EDT
Recruiting Not applicable Interventional

Effects of rTMS on Food Choice in Anorexia Nervosa

NCT05918835
View directory record Official record
Conditions
Anorexia Nervosa
Interventions
High-frequency repetitive transcranial magnetic stimulation (active rTMS), Sham repetitive transcranial magnetic stimulation (sham rTMS)
Device
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 19, 2026, 1:04 PM EDT
Recruiting Not applicable Interventional

BTL Emsella Chair Versus Sham for the Treatment of Overactive Bladder

NCT04873037
View directory record Official record
Conditions
Overactive Bladder Syndrome, Overactive Bladder, Urinary Frequency, Urinary Urgency
Interventions
BTL Emsella Chair, Sham BTL Emsella Chair
Device
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 19, 2026, 1:04 PM EDT
Active, not recruiting Not applicable Interventional

Electroacupuncture for the Management of Symptom Clusters in Cancer Patients and Survivors

NCT05283577
View directory record Official record
Conditions
Cancer
Interventions
Electroacupuncture, Sham-Electroacupuncture
Other
Lead sponsor
University of California, Irvine
Other
Eligibility
16 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Jan 23, 2026 · Synced Oct 19, 2026, 1:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of OMT on Functional Outcomes and Anti-inflammatory Biomarkers in Mild to Moderate Traumatic Brain Injury

NCT03163901
View directory record Official record
Conditions
Vestibular Disorder, Headache, Traumatic Brain Injury
Interventions
Osteopathic Manipulative Treatment
Other
Lead sponsor
Michigan State University
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Mason, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 24, 2020 · Synced Oct 19, 2026, 1:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Prefrontal Cortex Stimulation on Antisocial and Aggressive Behavior

NCT02427672
View directory record Official record
Conditions
Antisocial Behavior, Aggression
Interventions
Transcranial direct current stimulation, Sham transcranial direct current stimulation
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 19, 2026, 1:04 PM EDT
Completed Not applicable Interventional

Individualized Non-invasive Brain Stimulation for the Treatment of Major Depressive Disorder

NCT06874374
View directory record Official record
Conditions
Depression - Major Depressive Disorder, Transcranial Alternating Current Stimulation
Interventions
Closed-loop tACS, Sham Comparator
Device
Lead sponsor
Pulvinar Neuro, LLC
Industry
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 19, 2026, 1:04 PM EDT
Completed Phase 3 Interventional

EEG/Event-related Brain Potential Risk Markers as Predictors and Outcomes of SUD Treatment in Adolescents

NCT02016378
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Bias retraining, Sham retraining
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
14 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 13, 2022 · Synced Oct 19, 2026, 1:04 PM EDT
Recruiting Not applicable Interventional

Closed-Loop Transcranial Alternating Current Stimulation for the Treatment of Major Depressive Disorder

NCT07282678
View directory record Official record
Conditions
Depression - Major Depressive Disorder, Transcranial Alternating Current Stimulation
Interventions
Closed-loop tACS, Sham Comparator
Device
Lead sponsor
Pulvinar Neuro, LLC
Industry
Eligibility
22 Years and older
Enrollment
214 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 19, 2026, 1:04 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neuromodulation of Memory in Aging

NCT05460468
View directory record Official record
Conditions
Mild Cognitive Impairment, MCI
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 75 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 19, 2026, 1:04 PM EDT
Completed Not applicable Interventional

Osteopathic Manual Medicine Treatment in Autism

NCT01676389
View directory record Official record
Conditions
Autism Spectrum Disorders
Interventions
Sham OMM, Osteopathic Manual Medicine (Body Therapy)
Other
Lead sponsor
New York Institute of Technology
Other
Eligibility
3 Years to 11 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
2
States / cities
Central Islip, New York • Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Jan 21, 2016 · Synced Oct 19, 2026, 1:04 PM EDT
Recruiting Phase 2 Interventional

Apimostinel + Automated Neurocognitive Training for Depression

NCT06400121
View directory record Official record
Conditions
Depression
Interventions
Apimostinel Infusion, Intravenous, Cognitive Training, Sham Training, Isotonic Solution, Intravenous
Drug · Behavioral
Lead sponsor
Rebecca Price
Other
Eligibility
18 Years to 60 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 19, 2026, 1:04 PM EDT
Terminated Not applicable Interventional Results available

Transcranial Direct Current Stimulation (tDCS) in Pediatric Obsessive Compulsive Disorder (OCD)

NCT04548609
View directory record Official record
Conditions
Obsessive-Compulsive Disorder, Pediatric Psychiatric Disorder
Interventions
Transcranial Direct Current Stimulation
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
10 Years to 17 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 19, 2026, 1:04 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Treatment of Central Retinal Vein Occlusion Using Stem Cells Study

NCT03981549
View directory record Official record
Conditions
Central Retinal Vein Occlusion
Interventions
Autologous Bone Marrow CD34+ Stem Cells, Sham Therapy
Biological
Lead sponsor
The Emmes Company, LLC
Industry
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Dec 2, 2024 · Synced Oct 19, 2026, 1:04 PM EDT
Not listed Phase 2 Interventional

Pilot Study of Topical Steroid for Prevention of Chronic Lung Disease in Extremely Premature Infants.

NCT01268215
View directory record Official record
Conditions
Bronchopulmonary Dysplasia
Interventions
Infasurf, Pulmicort, Sham
Drug · Other
Lead sponsor
East Carolina University
Other
Eligibility
24 Weeks to 28 Weeks
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 29, 2010 · Synced Oct 19, 2026, 1:04 PM EDT
Active, not recruiting Not applicable Interventional Results available

Parkinson's Disease: Enhancing Physical Therapy With Brain Stimulation for Treating Postural Instability.

NCT03981055
View directory record Official record
Conditions
Parkinson Disease
Interventions
Active Comparator: Active tDCS and Active TUS, Sham Comparator: Sham TDCS and Sham TUS, Physical Therapy
Device · Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
40 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Oct 19, 2026, 1:04 PM EDT