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ClinicalTrials.gov public records Last synced Oct 20, 2026, 12:29 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 745–768 of 1,011 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Sham Condition Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Targeting Language-specific and Executive-control Networks With Transcranial Direct Current Stimulation in Logopenic Variant PPA

NCT03887481
View directory record Official record
Conditions
Logopenic Progressive Aphasia, Primary Progressive Aphasia
Interventions
High-definition active tDCS (HD-tDCS) + "Repeat After Me" (RAM) Treatment, Sham + "Repeat After Me" (RAM) Treatment
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 20, 2026, 12:29 AM EDT
Completed Not applicable Interventional Results available

STimulation to Improve Auditory haLLucinations

NCT02360228
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder
Interventions
tACS (alpha), tDCS
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 27, 2018 · Synced Oct 20, 2026, 12:29 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Study to Investigate Vagus Nerve Stimulation to Augment Executive Function in Healthy and Cognitively Impaired Populations

NCT07424365
View directory record Official record
Conditions
Mild Cognitive Impairment (MCI), Parkinsons Disease (PD), Healthy Adult
Interventions
transcutaneous auricular vagus nerve stimulation, sham stimulation
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 20, 2026 · Synced Oct 20, 2026, 12:29 AM EDT
Not listed Phase 3 Interventional

EASE Trial: Exhale Airway Stents for Emphysema

NCT00391612
View directory record Official record
Conditions
Emphysema
Interventions
Exhale® Drug-Eluting Stent, Sham control
Device
Lead sponsor
Broncus Technologies
Industry
Eligibility
35 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
26
States / cities
Phoenix, Arizona • Fresno, California • Los Angeles, California + 21 more
Source: ClinicalTrials.gov public record
Updated Jan 12, 2011 · Synced Oct 20, 2026, 12:29 AM EDT
Not listed Not applicable Interventional

Randomized Controlled Trial of a Behavioral Training App

NCT06447909
View directory record Official record
Conditions
Behavior, Child, Disruptive Behavior, Executive Dysfunction, Attention-deficit, Anxiety, Depression, Stress
Interventions
Treatment App, Sham app
Behavioral
Lead sponsor
New York University
Other
Eligibility
6 Years to 12 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 7, 2024 · Synced Oct 20, 2026, 12:29 AM EDT
Terminated Not applicable Interventional

TMS as a Treatment for Apathy in Alzheimer's Disease

NCT05389644
View directory record Official record
Conditions
Alzheimer Disease, Apathy in Dementia
Interventions
Intermittent Theta Burst Stimulation (iTBS)
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
50 Years to 80 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 15, 2025 · Synced Oct 20, 2026, 12:29 AM EDT
Completed Not applicable Interventional

Remote Study of NightWare for PTSD With Nightmares

NCT03934658
View directory record Official record
Conditions
PostTraumatic Stress Disorder, Sleep Disorder, Stress Disorder, Sleep Initiation and Maintenance Disorders, Combat Disorders, Nightmares Associated With Chronic Post-Traumatic Stress Disorder, Nightmare, Nightmares, REM-Sleep Type
Interventions
NightWare Therapeutic System, NightWare Therapeutic System in Sham Mode
Device
Lead sponsor
NightWare
Industry
Eligibility
18 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jan 28, 2022 · Synced Oct 20, 2026, 12:29 AM EDT
Recruiting Phase 1 Interventional

Using taVNS to Modulate Cardiovascular Function in Individuals With Neurologic Disease

NCT07557706
View directory record Official record
Conditions
PARKINSON DISEASE (Disorder)
Interventions
transcutaneous auricular vagus nerve stimulation
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 20, 2026, 12:29 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Novel Brain Stimulation Therapies in Stroke Guided Expressions of Plasticity

NCT03020433
View directory record Official record
Conditions
Stroke, Cerebrovascular Disorders, Nervous System Diseases, Brain Diseases, Cardiovascular Diseases, Vascular Diseases, Central Nervous System Diseases
Interventions
rTMS Contralesional M1, rTMS Contralesional PMC, rTMS Ipsilesional PMC, rTMS sham at Ipsilesional M1
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
21 Years and older
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 16, 2020 · Synced Oct 20, 2026, 12:29 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Modified Brostrӧm Procedure With and Without Possible Arthroscopy for Lateral Ankle Instability

NCT02470338
View directory record Official record
Conditions
Lateral Ankle Instability
Interventions
MBP plus arthroscopy (Group A), MBP alone (Group B)
Procedure
Lead sponsor
Edna Rath
Federal
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Sep 25, 2025 · Synced Oct 20, 2026, 12:29 AM EDT
Completed Not applicable Interventional Results available

Four-week Open-trial Extension TNS for ADHD

NCT03870737
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder (ADHD)
Interventions
Active TNS
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
8 Years to 12 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 29, 2019 · Synced Oct 20, 2026, 12:29 AM EDT
Completed Not applicable Interventional Results available

rTMS in First Episode Psychosis

NCT02131129
View directory record Official record
Conditions
Schizophrenia, Schizophreniform Disorder, Schizoaffective Disorder
Interventions
rTMS, Sham Comparator
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 40 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 19, 2023 · Synced Oct 20, 2026, 12:29 AM EDT
Completed Not applicable Interventional

Effect of Transcutaneous Vagal Stimulation (TVS) on Endothelial Function in PAD

NCT03445754
View directory record Official record
Conditions
Peripheral Artery Disease, Endothelial Dysfunction, Autonomic Imbalance
Interventions
TVS, Sham TVS
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 85 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Oct 20, 2026, 12:29 AM EDT
Completed Not applicable Interventional Results available

A Pilot Study of TMS Effects on Pain and Depression in Patients With Fibromyalgia

NCT00523302
View directory record Official record
Conditions
Major Depression, Fibromyalgia
Interventions
Active TMS, Sham TMS
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 11, 2018 · Synced Oct 20, 2026, 12:29 AM EDT
Not listed Not applicable Interventional

Augmenting Cognitive Behavioral Therapy With Inhibitory Control Training

NCT04076553
View directory record Official record
Conditions
Binge-Eating Disorder, Bulimia Nervosa
Interventions
CBT, ICT
Behavioral
Lead sponsor
Drexel University
Other
Eligibility
18 Years to 55 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 9, 2021 · Synced Oct 20, 2026, 12:29 AM EDT
Completed Phase 2 Interventional Results available

Zimura Compared to Sham in Patients With Autosomal Recessive Stargardt Disease (STGD1)

NCT03364153
View directory record Official record
Conditions
Stargardt's Macular Dystrophy
Interventions
avacincaptad pegol, Sham
Drug
Lead sponsor
Astellas Pharma Global Development, Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
17
States / cities
Phoenix, Arizona • Los Angeles, California • Gainesville, Florida + 14 more
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Oct 20, 2026, 12:29 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Temporal Interference Methods for Non-invasive Deep Brain Stimulation, Study 1.3

NCT07594795
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Temporal Interference (TI) Electrical Stimulation - dACC 20 Hz TI Active, Temporal Interference (TI) Electrical Stimulation - dACC 20 Hz TI Sham, Temporal Interference (TI) Electrical Stimulation - dACC Comparison Frequency TI Active, Temporal Interference (TI) Electrical Stimulation - dACC Comparison Frequency TI Sham
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 20, 2026, 12:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Changing Thought and Action in Tobacco Dependence With Transcranial Magnetic Stimulation

NCT00973622
View directory record Official record
Conditions
Tobacco Dependence
Interventions
repetitive transcranial magnetic stimulation (rTMS) 10 Hertz (Hz), repetitive transcranial magnetic stimulation (rTMS) 20Hz, SHAM repetitive transcranial magnetic stimulation (rTMS)
Device
Lead sponsor
University of Arkansas
Other
Eligibility
19 Years to 55 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Sep 24, 2013 · Synced Oct 20, 2026, 12:29 AM EDT
Recruiting Not applicable Interventional

Cerebellar Deep Brain Stimulation for Movement Disorders in Cerebral Palsy in Children and Young Adults

NCT06122675
View directory record Official record
Conditions
Dyskinetic Cerebral Palsy, Dystonic Cerebral Palsy
Interventions
DBS
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
7 Years to 25 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 5, 2026 · Synced Oct 20, 2026, 12:29 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Temporal Interference Neurostimulation and Addiction

NCT04432064
View directory record Official record
Conditions
Nicotine Use Disorder, Substance Use Disorders
Interventions
Active TI-NDBS, Sham TI-NDBS, tDCS
Device · Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 50 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 24, 2025 · Synced Oct 20, 2026, 12:29 AM EDT
Active, not recruiting Not applicable Interventional

Network-targeted Theta-burst Stimulation for Episodic Memory Improvement in Mild Cognitive Impairment

NCT04558164
View directory record Official record
Conditions
Cognitive Dysfunction, Memory Disorders in Old Age
Interventions
Active Theta Burst Stimulation, Sham Theta Burst Stimulation
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
55 Years to 100 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 20, 2026, 12:29 AM EDT
Not yet recruiting Not applicable Interventional

Noninvasive Brain Stimulation Combined With Written Exposure Therapy for PTSD in Military Personnel With TBI

NCT07715799
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Transcranial Direct Current Stimulator, Written Exposure Therapy
Device · Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 70 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 20, 2026, 12:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Using Combined EEG and Non-invasive Brain Stimulation to Examine and Improve Reward Functioning in Opioid Use Disorder

NCT04432493
View directory record Official record
Conditions
Opioid-use Disorder
Interventions
Active repetitive transcranial magnetic stimulation (rTMS), Sham repetitive transcranial magnetic stimulation (rTMS)
Device
Lead sponsor
Rutgers University
Other
Eligibility
18 Years to 55 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 8, 2024 · Synced Oct 20, 2026, 12:29 AM EDT
Completed Not applicable Interventional

The RA PROTECTION Study

NCT04306744
View directory record Official record
Conditions
Rheumatoid Arthritis
Interventions
Vorso PROTECT System, Vorso PROTECT System - Sham (OFF)
Device
Lead sponsor
Nesos Corp
Industry
Eligibility
18 Years to 80 Years
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Duncansville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 30, 2023 · Synced Oct 20, 2026, 12:29 AM EDT