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ClinicalTrials.gov public records Last synced Oct 21, 2026, 5:55 AM EDT

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Showing 337–360 of 519 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Sham Control Device Clear all
Completed Not applicable Interventional

Acupuncture in Reducing Muscle and Bone Symptoms in Women Receiving Letrozole, Exemestane, or Anastrozole for Stage 0, Stage I, Stage II, or Stage III Breast Cancer

NCT00641303
View directory record Official record
Conditions
Anxiety Disorder, Breast Cancer, Depression, Fatigue, Hot Flashes, Pain, Sleep Disorders
Interventions
acupuncture therapy, sham intervention
Procedure
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older · Female only
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 8, 2023 · Synced Oct 21, 2026, 5:55 AM EDT
Completed Not applicable Interventional

FemPulse Therapy First-in-Human Experience

NCT03874637
View directory record Official record
Conditions
Urinary Bladder, Overactive
Interventions
Treament, Sham Control
Device
Lead sponsor
FemPulse Corporation
Industry
Eligibility
21 Years and older · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
2
States / cities
Woodbury, Minnesota • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 14, 2019 · Synced Oct 21, 2026, 5:55 AM EDT
Completed Not applicable Interventional Results available

Acute Treatment of Migraine With e-TNS

NCT02590939
View directory record Official record
Conditions
Migraine
Interventions
CEFALY Active, CEFALY Placebo
Device
Lead sponsor
Cefaly Technology
Industry
Eligibility
18 Years to 65 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
3
States / cities
New Haven, Connecticut • Lenexa, Kansas • New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 6, 2018 · Synced Oct 21, 2026, 5:55 AM EDT
Recruiting Not applicable Interventional

Therapeutic Evaluative Conditioning to Reduce Adolescents' Self-injurious Thoughts and Behaviors During and After Psychiatric Inpatient Hospitalization

NCT05796531
View directory record Official record
Conditions
Self-Injurious Behavior, Suicidal Ideation, Suicide Attempts
Interventions
Therapeutic Evaluative Conditioning, Neutral comparison condition
Behavioral
Lead sponsor
Franciscan Hospital For Children, INC.
Other
Eligibility
12 Years to 19 Years
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Brighton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 12, 2024 · Synced Oct 21, 2026, 5:55 AM EDT
Terminated Phase 1 Interventional Results available

Stellate Ganglion Blockade in Corona Virus 2019 (COVID-19) Positive Patients

NCT04445337
View directory record Official record
Conditions
COVID 19, ARDS
Interventions
Stellate Ganglion Block
Drug
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 85 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Jan 20, 2025 · Synced Oct 21, 2026, 5:55 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Heat Therapy, Functional Capacity, and Vascular Health in Older Adults

NCT05706181
View directory record Official record
Conditions
Aging Well, Walking, Difficulty, Hyperemia
Interventions
Home-based leg heat therapy, Home-based sham therapy
Other
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
55 Years to 80 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jun 5, 2026 · Synced Oct 21, 2026, 5:55 AM EDT
Completed Phase 1 Interventional

Trial of Early Noninvasive Ventilation for Amyotrophic Lateral Sclerosis (ALS)

NCT00580593
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis
Interventions
BiPAP® S/T System, sham-NIPPV
Device · Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 79 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 10, 2013 · Synced Oct 21, 2026, 5:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Latera RCT - Latera vs. Sham Control for Lateral Nasal Valve Collapse

NCT03400787
View directory record Official record
Conditions
Nasal Valve Collapse, Nasal Breathing
Interventions
Latera Implant, Sham Procedure
Device
Lead sponsor
Spirox, Inc.
Industry
Eligibility
18 Years and older
Enrollment
137 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
11
States / cities
Roseville, California • Torrance, California • Atlanta, Georgia + 8 more
Source: ClinicalTrials.gov public record
Updated Feb 9, 2021 · Synced Oct 21, 2026, 5:55 AM EDT
Terminated Not applicable Interventional Results available

Safety and Efficacy of EndoBarrier in Subjects With Type 2 Diabetes Who Are Obese

NCT01728116
View directory record Official record
Conditions
Type 2 Diabetes, Obesity
Interventions
EndoBarrier, Sham Procedure
Device · Procedure
Lead sponsor
Morphic Medical Inc.
Industry
Eligibility
21 Years to 65 Years
Enrollment
325 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
25
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Little Rock, Arkansas + 20 more
Source: ClinicalTrials.gov public record
Updated Feb 1, 2017 · Synced Oct 21, 2026, 5:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Stress and Sleep Study

NCT05218109
View directory record Official record
Conditions
Stress, Psychological, Sleep, Transcutaneous Electric Nerve Stimulation, Vagus Nerve Stimulation, Mindfulness
Interventions
tVNS, Mindfulness, sham tVNS, Number Puzzle
Device · Behavioral · Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 30 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 4, 2024 · Synced Oct 21, 2026, 5:55 AM EDT
Terminated No phase listed Observational

The Effects of Pulsed Elelectro-Magnetic Fields ("PEMF") in the Treatment of Venous Stasis Leg Ulcers

NCT03416049
View directory record Official record
Conditions
Venous Stasis Ulcers
Interventions
PEMF therapy with a high-power PEMF device, PEMF therapy with a medium PEMF power device, PEMF therapy with a low-power PEMF device, PEMF therapy with the sham PEMF device
Device
Lead sponsor
PEMF Systems, Inc.
Industry
Eligibility
21 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 5, 2024 · Synced Oct 21, 2026, 5:55 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Acupressure for Fatigue in Systemic Lupus Erythematosus

NCT03200548
View directory record Official record
Conditions
Fatigue, Lupus Erythematosus, Systemic, Pain, Chronic, Quality of Life, Sleep
Interventions
Relaxing acupressure plus usual care, Usual care, Stimulating acupressure plus usual care, Sham acupressure plus usual care
Behavioral
Lead sponsor
Suzanna Zick
Other
Eligibility
18 Years and older · Female only
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 12, 2023 · Synced Oct 21, 2026, 5:55 AM EDT
Not listed Phase 2 Interventional

Study of Low-level Laser Therapy in the Acute Treatment of Migraine

NCT02969642
View directory record Official record
Conditions
Migraine Headache
Interventions
Argus Migraine Treatment device
Device
Lead sponsor
The San Francisco Clinical Research Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 2, 2016 · Synced Oct 21, 2026, 5:55 AM EDT
Completed Not applicable Interventional Results available

Pilot Study of PEMF Therapy in Treatment of Post-operative Pain Following Total Knee Arthroplasty

NCT02211534
View directory record Official record
Conditions
Post-Operative Pain Following Total Knee Arthroplasty
Interventions
Pulsed Electromagnetic Field Device (Provant), Sham Pulsed Electromagnetic Field Device
Device
Lead sponsor
Regenesis Biomedical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
14
States / cities
Birmingham, Alabama • Phoenix, Arizona • El Cajon, California + 10 more
Source: ClinicalTrials.gov public record
Updated Oct 27, 2017 · Synced Oct 21, 2026, 5:55 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

BRIDGE Device for Treatment of Opioid Withdrawal

NCT04162145
View directory record Official record
Conditions
Opioid Withdrawal, Pain, Craving
Interventions
Active BRIDGE device placement, Inactive BRIDGE device placement
Device
Lead sponsor
BrightView LLC
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
2
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 25, 2020 · Synced Oct 21, 2026, 5:55 AM EDT
Enrolling by invitation Not applicable Interventional

Study to Investigate Vagus Nerve Stimulation Paired With Motor Task for Remyelination and Functional Recovery

NCT06641271
View directory record Official record
Conditions
Multiple Sclerosis (MS) - Relapsing-remitting, Multiple Sclerosis
Interventions
Closed Loop Trans-Auricular Vagus Nerve Stimulation System, Placebo
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 70 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 21, 2026, 5:55 AM EDT
Terminated Not applicable Interventional Results available

An Investigation of the EndoStim® Lower Esophageal Sphincter (LES) Stimulation System for the Treatment of Reflux

NCT02749071
View directory record Official record
Conditions
Gastroesophageal Reflux Disease (GERD), Reflux, Gastroesophageal, Gastroesophageal Reflux, Acid Reflux
Interventions
Laparoscopic implantation surgery with or without crural repair, EndoStim stimulation for first six months of study, EndoStim stimulation from Month 6 thru end of study, Sham EndoStim stimulation for first six months of study
Procedure · Device
Lead sponsor
EndoStim Inc.
Industry
Eligibility
22 Years to 75 Years
Enrollment
161 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
18
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Los Angeles, California + 13 more
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 21, 2026, 5:55 AM EDT
Completed Not applicable Interventional Results available

Duchenne Muscular Dystrophy Clinical Trial

NCT01874275
View directory record Official record
Conditions
Duchenne Muscular Dystrophy
Interventions
VECTTOR
Device
Lead sponsor
Alan Neuromedical Technologies, LLC
Industry
Eligibility
8 Years to 20 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 4, 2015 · Synced Oct 21, 2026, 5:55 AM EDT
Completed Not applicable Interventional Results available

Inspiratory Muscle Rehabilitation in Children With Obesity

NCT05412134
View directory record Official record
Conditions
Pediatric Obesity
Interventions
Pro2 - 75% of participant's MIP, Pro2 - 15% of participant's MIP
Device
Lead sponsor
Duke University
Other
Eligibility
8 Years to 17 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 18, 2024 · Synced Oct 21, 2026, 5:55 AM EDT
Not listed Phase 3 Interventional

Study of the Application of Magnetic Fields for the Treatment of Parkinson's Disease

NCT00863226
View directory record Official record
Conditions
Parkinson's Disease, Quality of Life
Interventions
Resonator Device
Device
Lead sponsor
pico-tesla Magnetic Therapies, LLC
Industry
Eligibility
30 Years to 85 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
6
States / cities
Aurora, Colorado • Denver, Colorado • Englewood, Colorado + 3 more
Source: ClinicalTrials.gov public record
Updated Dec 14, 2011 · Synced Oct 21, 2026, 5:55 AM EDT
Recruiting Not applicable Interventional

Safety and Effectiveness of eGERD Device to Reduce Gastroesophageal Reflux Disease (GERD) Symptoms

NCT06613438
View directory record Official record
Conditions
GERD (Gastroesophageal Reflux Disease)
Interventions
eGERD device, eGERD_Sham
Device
Lead sponsor
Gerd Care Medical Ltd
Industry
Eligibility
22 Years to 75 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 21, 2026, 5:55 AM EDT
Completed Not applicable Interventional

Auricular Vagus Nerve Stimulation (aVNS) in Chronic Spinal Cord Injuries (SCI)

NCT06588608
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
auricular nerve stimulation (aVNS), sham aVNS
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 21, 2026, 5:55 AM EDT
Not listed Early Phase 1 Interventional

Photobiomodulation to Improve Cognition in TBI, With fMRI

NCT04230577
View directory record Official record
Conditions
Traumatic Brain Injury, Closed Head Injury, Cognitive Dysfunction
Interventions
Real LED Intervention, Sham LED Intervention
Device
Lead sponsor
Boston VA Research Institute, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 25, 2022 · Synced Oct 21, 2026, 5:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Psychophysiologic Predictors of Post-deployment Mental Health Outcomes

NCT00838006
View directory record Official record
Conditions
Post-traumatic Stress Disorder
Interventions
heart rate variability biofeedback, Cognitive bias modification training, Sham Comparator
Device
Lead sponsor
Biomedical Research Foundation
Other
Eligibility
18 Years to 60 Years
Enrollment
426 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Blackstone, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 2, 2020 · Synced Oct 21, 2026, 5:55 AM EDT