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ClinicalTrials.gov public records Last synced Oct 22, 2026, 3:31 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 457–480 of 519 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Sham Control Device Clear all
Not listed Not applicable Interventional

AVPI Migraine Study

NCT05537818
View directory record Official record
Conditions
Migraine
Interventions
AVPI Device
Device
Lead sponsor
Nocira, LLC
Industry
Eligibility
18 Years to 75 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
3
States / cities
Scottsdale, Arizona • Saint Charles, Missouri • Springfield, Missouri
Source: ClinicalTrials.gov public record
Updated May 10, 2023 · Synced Oct 22, 2026, 3:31 AM EDT
Completed Not applicable Interventional

Safety and Feasibility of Paired Vagus Nerve Stimulation With Rehabilitation for Improving Upper Extremity Function in People With Cervical Spinal Cord Injury

NCT05601661
View directory record Official record
Conditions
Cervical Spinal Cord Injury
Interventions
Active VNS, Sham VNS, Arm rehabilitation
Device · Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 28, 2025 · Synced Oct 22, 2026, 3:31 AM EDT
Completed Phase 1 Interventional Results available

Electrical Stimulation for Critically Ill Covid-19 Patients

NCT04685213
View directory record Official record
Conditions
Covid19, Muscle Atrophy, Muscle Weakness
Interventions
Electrical Stimulation, Electrical Stimulation - Sham
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 100 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 16, 2023 · Synced Oct 22, 2026, 3:31 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

BRIDGE Device for Treatment of Opioid Withdrawal

NCT04162145
View directory record Official record
Conditions
Opioid Withdrawal, Pain, Craving
Interventions
Active BRIDGE device placement, Inactive BRIDGE device placement
Device
Lead sponsor
BrightView LLC
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
2
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 25, 2020 · Synced Oct 22, 2026, 3:31 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Role of Sympathetic Overactivity and Angiotensin II in PTSD and CV

NCT02560805
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Microneurography, Combat virtual reality video clip, Handgrip Exercise, Cold Pressor Test (CPT), Sodium Nitroprusside (SNP), Phenylephrine, Losartan, Atenolol, Transcutaneous Vagal Nerve Stimulation (tVNS), Sham Transcutaneous Vagal Nerve Stimulation (tVNS)
Procedure · Behavioral · Drug + 1 more
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2027
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 22, 2026, 3:31 AM EDT
Not listed Not applicable Interventional

Treatment of Fibromyalgia With the FibroNova Neuromodulation Device

NCT06271746
View directory record Official record
Conditions
Fibromyalgia
Interventions
FibroNova (Active mode), FibroNova (Sham mode)
Device
Lead sponsor
Theranica
Industry
Eligibility
18 Years to 70 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
3
States / cities
Chesterfield, Missouri • Springfield, Missouri • Virginia Beach, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 11, 2024 · Synced Oct 22, 2026, 3:31 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effect of Surface Acoustic Waves on the Prevention of Colonization in Longterm Indwelling Urinary Caatheters

NCT03090373
View directory record Official record
Conditions
Baacterial Colonization, Urinary Tract Infections
Interventions
UroShield
Device
Lead sponsor
Rosenblum, Jonathan I., DPM
Individual
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Elmsford, New York
Source: ClinicalTrials.gov public record
Updated Mar 24, 2017 · Synced Oct 22, 2026, 3:31 AM EDT
Not yet recruiting Phase 1 Interventional

Nanopulse Laser Therapy

NCT07520383
View directory record Official record
Conditions
TBI (Traumatic Brain Injury)
Interventions
Nano-Pulsed Laser Therapy (NPLT)
Device
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 22, 2026, 3:31 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Improving Social Interaction for Adolescents With Autism During the Transition to Adulthood

NCT03785327
View directory record Official record
Conditions
Autism Spectrum Disorder, Typical Development
Interventions
tDCS, Autism Training
Device · Behavioral
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
18 Years to 21 Years · Male only
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Dec 23, 2022 · Synced Oct 22, 2026, 3:31 AM EDT
Recruiting Not applicable Interventional

Non-Invasive Low Intensity Focused Ultrasound Stimulation for Drug-Resistant Epilepsy

NCT07680842
View directory record Official record
Conditions
Drug-Resistant Epilepsy, Epilepsy, Epilepsy (Treatment Refractory), Epilepsy Comorbidities, Epilepsy, Drug Resistant, Epilepsy, Generalized, Epilepsy, Focal
Interventions
Target optimization using LIFU, Serial LIFU stimulation
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 2, 2026 · Synced Oct 22, 2026, 3:31 AM EDT
Completed Not applicable Interventional

Gamma Sensory Flicker for Parkinson's Disease Patients With Freezing of Gait

NCT06295458
View directory record Official record
Conditions
Gait Disorders, Neurologic, Parkinson Disease
Interventions
David Delight Plus Device, Sham Therapy
Device · Other
Lead sponsor
Emory University
Other
Eligibility
50 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Oct 22, 2026, 3:31 AM EDT
Terminated Not applicable Interventional Results available

Safety and Efficacy Study of Autologous Concentrated Bone Marrow Aspirate (cBMA) for Critical Limb Ischemia (CLI)

NCT01049919
View directory record Official record
Conditions
Critical Limb Ischemia, Peripheral Arterial Disease, Peripheral Vascular Disease
Interventions
Bone marrow concentration device, Placebo procedure (sham)
Device · Procedure
Lead sponsor
Zimmer Biomet
Industry
Eligibility
21 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2020
U.S. locations
25
States / cities
Little Rock, Arkansas • Sacramento, California • Miami, Florida + 20 more
Source: ClinicalTrials.gov public record
Updated May 28, 2021 · Synced Oct 22, 2026, 3:31 AM EDT
Completed Not applicable Interventional Results available

Percutaneous Auricular Neuromodulation for Postoperative Analgesia

NCT05521516
View directory record Official record
Conditions
Postoperative Pain, Acute
Interventions
Active Percutaneous Auricular Neuromodulation with NSS-2 Bridge, Sham Treatment
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 4, 2025 · Synced Oct 22, 2026, 3:31 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Efficacy of Cranial Electrotherapy Stimulation (CES) for the Treatment of Major Depressive Disorder

NCT03222752
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Cranial Electrotherapy Stimulation, Sham Cranial Electrotherapy Stimulation
Device
Lead sponsor
Electromedical Products International, Inc.
Industry
Eligibility
22 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Forest, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 27, 2023 · Synced Oct 22, 2026, 3:31 AM EDT
Completed Not applicable Interventional

Prospective Evaluation of RINCE to Reduce Fibromyalgia Effects - 202

NCT02613949
View directory record Official record
Conditions
Fibromyalgia
Interventions
RINCE
Device
Lead sponsor
Cerephex Corporation
Industry
Eligibility
22 Years to 75 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
4
States / cities
Birmingham, Alabama • Sacramento, California • Chicago, Illinois + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2018 · Synced Oct 22, 2026, 3:31 AM EDT
Recruiting Not applicable Interventional

BFRT for Subacromial Pain

NCT06873113
View directory record Official record
Conditions
Shoulder Pain
Interventions
Active BFRT, Sham BFRT, Strengthening Exercises with BFRT, Skilled Physical Therapy Care
Device · Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 50 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 8, 2025 · Synced Oct 22, 2026, 3:31 AM EDT
Completed Not applicable Interventional

Randomized Blinded Evaluation of the Effects of TENS and IFC Compared to a Sham Device and SOC in Patients With Non-Specific CLBP

NCT05972889
View directory record Official record
Conditions
Non-Specific Chronic Lower Back Pain
Interventions
NexWave, Sham
Device
Lead sponsor
Zynex Medical, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
334 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
8
States / cities
Greenwood Village, Colorado • Saint Augustine, Florida • Atlanta, Georgia + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 28, 2025 · Synced Oct 22, 2026, 3:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

RhinAer Procedure for Treatment of Chronic Rhinitis Study

NCT04533438
View directory record Official record
Conditions
Chronic Rhinitis
Interventions
RhinAer Stylus, Sham
Device
Lead sponsor
Aerin Medical
Industry
Eligibility
18 Years to 85 Years
Enrollment
116 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
13
States / cities
Roseville, California • Torrance, California • Plantation, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated May 2, 2025 · Synced Oct 22, 2026, 3:31 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Clinical Study Evaluating Nordlys™ SWT IPL for Dry Eye Disease (DED) Due to MGD

NCT06064071
View directory record Official record
Conditions
Meibomian Gland Dysfunction, Dry Eye Disease
Interventions
Nordlys SWT IPL, Meibomian Gland Expression (MGX), Sham Nordlys SWT IPL
Device · Procedure
Lead sponsor
Candela Corporation
Industry
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
2
States / cities
Miami, Florida • Marlborough, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 22, 2025 · Synced Oct 22, 2026, 3:31 AM EDT
Completed Not applicable Interventional Results available

Adaptive Design Study of NEST sTMS in Subjects With Major Depressive Disorder

NCT03288714
View directory record Official record
Conditions
Depressive Disorder, Depression, Depressive Disorder, Major, Depressive Episode, Major Depressive Disorder
Interventions
Synchronized Transcranial Magnetic Stimulation (sTMS), Sham Stimulation
Device
Lead sponsor
Wave Neuroscience
Industry
Eligibility
22 Years to 65 Years
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
14
States / cities
La Jolla, California • Los Angeles, California • Stanford, California + 11 more
Source: ClinicalTrials.gov public record
Updated Sep 5, 2021 · Synced Oct 22, 2026, 3:31 AM EDT
Completed Not applicable Interventional Results available

A Study to Evaluate the Safety and Effectiveness of Oculeve Intranasal Lacrimal Neurostimulator in Participants With Dry Eye Syndrome

NCT02680158
View directory record Official record
Conditions
Dry Eye Syndrome, Keratoconjunctivitis Sicca
Interventions
Oculeve Intranasal, Sham, Oculeve Extranasal
Device
Lead sponsor
Oculeve, Inc.
Industry
Eligibility
22 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
2
States / cities
Waterbury, Connecticut • Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 26, 2019 · Synced Oct 22, 2026, 3:31 AM EDT
Completed Not applicable Interventional

Respiratory Muscle Training in L-Onset Pompe Disease (LOPD)

NCT02801539
View directory record Official record
Conditions
Glycogen Storage Disease Type II
Interventions
RMT therapy using modified RMT device, Sham-RMT therapy using modified RMT device
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 30, 2019 · Synced Oct 22, 2026, 3:31 AM EDT
Completed Not applicable Interventional Results available

Acute Treatment of Migraine With e-TNS

NCT02590939
View directory record Official record
Conditions
Migraine
Interventions
CEFALY Active, CEFALY Placebo
Device
Lead sponsor
Cefaly Technology
Industry
Eligibility
18 Years to 65 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
3
States / cities
New Haven, Connecticut • Lenexa, Kansas • New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 6, 2018 · Synced Oct 22, 2026, 3:31 AM EDT
Recruiting Not applicable Interventional

Effects of Transcranial Focused Ultrasound Stimulation (tFUS) on Neurological and Cognitive Outcomes in Parkinson's Disease

NCT07207122
View directory record Official record
Conditions
Parkinson Disease
Interventions
Gen0Bh Transcranial Focused Ultrasound System (Active), Gen0Bh Transcranial Focused Ultrasound System (Sham)
Device
Lead sponsor
Sanmai Technologies PBC dba Sanmai
Industry
Eligibility
22 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
4
States / cities
Tucson, Arizona • Santa Monica, California • Gainesville, Florida + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 22, 2026, 3:31 AM EDT