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ClinicalTrials.gov public records Last synced Nov 4, 2026, 11:33 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 913–936 of 1,170 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sham Control Group Clear all

Conditions: Mild Cognitive Impairment
Interventions: Application of Transcranial Alternating Current Stimulation for Modulation of Sleep and Cognitive Performance; Device
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 80 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Ectasia
Interventions: VEGA UV-A Illumination System, Riboflavin; Device · Drug
Lead sponsor: Topcon Medical Systems, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 103 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 12
States / cities: Phoenix, Arizona • Atlanta, Georgia • Bloomington, Minnesota + 6 more

Conditions: Keratoconus
Interventions: Riboflavin and Sodium Iodide solution and Ultraviolet-A treatment, Placebo and sham treatment; Combination Product
Lead sponsor: Epion Therapeutics; Industry
Eligibility: 8 Years to 45 Years
Enrollment: 396 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 13
States / cities: Rowland Heights, California • San Francisco, California • Miami, Florida + 10 more

Conditions: Fall Risk, Fall Risk, Fall Prevention, Accidental Falls, Accidental Falls/Prevention & Control
Interventions: LIBERTY Patch, Sham Patch; Device
Lead sponsor: SuperPatch Limited LLC; Industry
Eligibility: 55 Years to 85 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Mansfield, Texas

Conditions: Myofascial Pain Syndrome (MPS), Chronic Low-back Pain (cLBP)
Interventions: Acupuncture, Sham Acupuncture, Total-Body PET/CT Imaging; Procedure
Lead sponsor: University of California, Davis; Other
Eligibility: 18 Years and older
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Fibromyalgia
Interventions: Lymphatic Enhancement Technology (LET), Sham Lymphatic Enhancement Technology (LET); Device
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Female Sexual Dysfunction
Interventions: percutaneous tibial nerve stimulation (PTNS), Sham procedure; Device
Lead sponsor: Stony Brook University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 79 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Stony Brook, New York

Conditions: Acupuncture, Pain, Range of Motion
Interventions: One Needle Hand Acupuncture with Movement, One Needle Hand Acupuncture without Movement, Control Acupuncture with Movement; Procedure
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 99 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Chesterfield, Missouri

Conditions: Pain, Virtual Reality, Placebo, Temporomandibular Disorder
Interventions: RelieVRx, Sham-VR, No-VR (natural history control); Device · Other
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years to 88 Years
Enrollment: 78 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 2
States / cities: Baltimore, Maryland

Conditions: Fibromyalgia, Healthy Volunteers
Interventions: EEG, Neuroimaging EEG/fMRI (Aim 1), HD-tDCS treatments, Sham HD-tDCS treatments, Neuroimaging EEG/fMRI (Aim 3); Diagnostic Test · Device
Lead sponsor: University of Michigan; Other
Eligibility: 19 Years to 74 Years
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2026
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: COPD, COPD - Chronic Obstructive Pulmonary Disease
Interventions: Activated ROAM System with User Feedback, Sham Comparator; Device
Lead sponsor: Barron Associates, Inc.; Industry
Eligibility: 21 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Stress Disorders, Post-Traumatic
Interventions: taVNS; Device
Lead sponsor: Northwell Health; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Manhasset, New York

Conditions: Ankyloglossia, Breast Feeding, Enlarged Labial Frenum
Interventions: Lingual Frenotomy, Labial Frenotomy, Sham Procedure; Procedure
Lead sponsor: University of South Florida; Other
Eligibility: Up to 2 Weeks
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Migraine
Interventions: Precision; Device
Lead sponsor: Boston Scientific Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 179 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2018
U.S. locations: 15
States / cities: Denver, Colorado • Stamford, Connecticut • Augusta, Georgia + 11 more

Conditions: Healthy Adults, Mechanical Ventilation Dependence, Hypoxia, Exercise Training, Exercise Intolerance, Dietary Supplement, Nitrate Supplementation, Inspiratory Muscle Training
Interventions: Respiratory Muscle Training (RMT), Sham Respiratory Muscle Training, Dietary Supplement: Beetroot Juice Concentrate, placebo beverage; Device · Dietary Supplement
Lead sponsor: Embry-Riddle Aeronautical University; Other
Eligibility: 18 Years to 40 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Daytona Beach, Florida

Conditions: Septic Shock
Interventions: Low Level Transcutaneous Vagus Nerve Stimulation; Device
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years and older
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2027
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Post Operative Delirium, Cognitive Impairment, Vagus Nerve Stimulation, Depression
Interventions: Transcutaneous vagal nerve stimulation, Sham (No Treatment); Device
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Amyotrophic Lateral Sclerosis (ALS)
Interventions: Transcranial Direct Current Stimulation (tDCS), Sham tDCS + anodal tDCS; Other
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 18 Years to 80 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Myocardial Infarction, Psychosocial Factors
Interventions: Gratitude Journaling Plus SOC, Memorable Events Journaling Plus SOC; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 35 Years and older
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Alzheimer's Disease
Interventions: Repetitive Transcranial Magnetic Stimulation (rTMS), NICE Cognitive Training; Device · Behavioral
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 55 Years to 90 Years
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Mild Cognitive Impairment, Early Alzheimer's Disease, Memory Impairment
Interventions: COT, Sham; Drug
Lead sponsor: Evon Medics LLC; Industry
Eligibility: 55 Years to 95 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 3
States / cities: Washington D.C., District of Columbia

Conditions: Multiple Sclerosis, Cognitive Impairment
Interventions: non-invasive transcranial electrical stimulation; Device
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 65 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Incomplete Spinal Cord Injury
Interventions: Acute Intermittent Hypoxia, SHAM Acute Intermittent Hypoxia; Other
Lead sponsor: University of Colorado, Boulder; Other
Eligibility: 18 Years to 70 Years
Enrollment: 56 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 2
States / cities: Aurora, Colorado • Boulder, Colorado

Conditions: Wound Healing and Prevention, Oral Inflammation, Photobiomodulation, Post-operative Pain Management, Tooth Extraction Site Healing
Interventions: Low-level laser therapy; Other
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years and older
Enrollment: 39 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Charleston, South Carolina

Search by objective public record fields.

Application of Transcranial Alternating Current Stimulation for Modulation of Sleep and Cognitive Performance

Safety Study of the VEGA UV-A System to Treat Ectasia

Epithelium-On Corneal Cross-linking in Subjects 8 to 45 Years of Age With Keratoconus

Prevention and Reduction of Falls: Testing and Evaluating Cutting Edge Haptic Technology

Imaging Metabolic and Perfusion Changes in Acupuncture Therapy for Myofascial Pain Syndrome

LET for Fibromyalgia

Trial of Tibial Nerve Stimulation for Treating Sexual Dysfunction

One Needle Hand Acupuncture for MSK Disorders

Neural Mechanisms of Immersive Virtual Reality in Chronic Pain (VR TMD EEG)

Explosive Synchronization of Brain Network Activity in Chronic Pain

Respiratory Oxygen Adherence Monitor for Chronic Obstructive Pulmonary Disease Patients

taVNS to Reduce PTSD Symptoms in WTC Responders

Prospective Evaluation of Lingual Frenotomy in Newborns With Simultaneous Lip Tie for the Relief of Breastfeeding Pain.

Treatment for Migraines With an Implantable Device

Effects of Breathing Training and Nitrate on Exercise at Simulated Altitude

Neuromodulation to Regulate Inflammation and Autonomic Imbalance in Sepsis

Effects of Transcutaneous Vagal Nerve Stimulation on Post-Surgical Return to Consciousness, Delirium, and Depression

Remotely Supervised tDCS for Slowing ALS Disease Progression

The Effects of Journaling on Health-Related Mood and Clinical Outcomes in Post-MI Patients

Effects of a Combined Transcranial Magnetic Stimulation (TMS) and Cognitive Training in Alzheimer Patients

Development and Evaluation of Computerized Olfactory Training Program for Cognitive Decline in Early Alzheimer's Disease

Non-invasive Transcranial Electrical Stimulation in MS

The Effect of Acute Intermittent Hypoxia on Motor Learning

Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva