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ClinicalTrials.gov public records Last synced Nov 5, 2026, 7:38 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 961–984 of 1,170 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sham Control Group Clear all

Conditions: ACL Injury
Interventions: Neuromuscular Training; Other
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 10 Years to 19 Years · Female only
Enrollment: 593 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Cardiovascular Diseases, Cardiovascular Risk Factor, Cardiovascular Health
Interventions: Singing with Music Therapist, Singing with Guided Video, Control Arm; Other
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 55 Years to 79 Years
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Rhinosinusitis Acute
Interventions: Sham Treatment, Facial Effleurage, Antibiotics; Other · Drug
Lead sponsor: Edward Via Virginia College of Osteopathic Medicine; Other
Eligibility: 18 Years to 69 Years
Enrollment: 138 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Spartanburg, South Carolina

Conditions: Chronic Low Back Pain, Opioid Use, Unspecified
Interventions: Cognitive Behavioral Therapy for Pain, Transcranial Direct Current Stimulation, Sham Transcranial Direct Current Stimulation; Behavioral · Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 70 Years
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2021
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Older Adults
Interventions: tVNS stimulation, Sham stimulation; Procedure
Lead sponsor: Georgia Institute of Technology; Other
Eligibility: 65 Years to 84 Years
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Depression
Interventions: Reclaim™ DBS System; Device
Lead sponsor: MedtronicNeuro; Industry
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 5
States / cities: Charlestown, Massachusetts • Cleveland, Ohio • Philadelphia, Pennsylvania + 2 more

Conditions: Obesity, Type II Diabetes, Cardiovascular Disease, Health Behavior
Interventions: STRIDES, Sham Control; Other
Lead sponsor: University of Rochester; Other
Eligibility: 18 Years and older
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Binge Drinking, Heavy Drinking, Young Adult, Heavy Drinker, Alcohol Drinking, Alcohol Drinking in College, Drinking Behavior, Drunkenness, Drinking Excessive, Drinking Problem, Drink Too Much, College Drinking
Interventions: Regulation of craving, Control (NO REGULATION); Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 25 Years
Enrollment: 57 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Brain Concussion, Mild Traumatic Brain Injury, Headache, Post-Concussion Symptoms
Interventions: Repetitive Transcranial Magnetic Stimulation, Sham Repetitive Transcranial Magnetic Stimulation; Device
Lead sponsor: State University of New York - Upstate Medical University; Other
Eligibility: 18 Years to 55 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Syracuse, New York

Conditions: Muscle Weakness
Interventions: High velocity low amplitude thoracic spine manipulation, Sham; Procedure
Lead sponsor: University of New England; Other
Eligibility: 18 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Portland, Maine

Conditions: Neck Pain
Interventions: BEMER, OMT, Sham OMT + Sham BEMER; Device · Procedure
Lead sponsor: Lake Erie College of Osteopathic Medicine; Other
Eligibility: Not listed
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Bradenton, Florida

Conditions: Development, Child
Interventions: Low Sweet, Regular Sweet; Behavioral
Lead sponsor: Temple University; Other
Eligibility: 3 Years to 6 Years
Enrollment: 172 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2024
U.S. locations: 2
States / cities: Philadelphia, Pennsylvania

Conditions: Hemorrhage, Surgical, Hemorrhage Postoperative, Blood Loss, Surgical, Blood Loss, Postoperative
Interventions: Sham comparator, DrugSorb-ATR system; Device
Lead sponsor: CytoSorbents, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 27
States / cities: Sacramento, California • Denver, Colorado • New Haven, Connecticut + 22 more

Conditions: Osteoarthritis, Knee
Interventions: Calibrated AposTherapy®, Non-Calibrated Sham Apos Therapy Device; Device
Lead sponsor: NYU Langone Health; Other
Eligibility: 45 Years to 75 Years
Enrollment: 77 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: New York, New York

Conditions: Obesity
Interventions: tDCS, Sham brain stimulation, Go-No GO task; Device · Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Fibromyalgia
Interventions: Energy Healing; Other
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years to 75 Years · Female only
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Irvine, California

Conditions: Congenital Heart Defect
Interventions: electro-acupuncture (EA), sham; Device
Lead sponsor: West Virginia University; Other
Eligibility: Up to 18 Years
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2024
U.S. locations: 1
States / cities: Morgantown, West Virginia

Conditions: Primary Cervical Dystonia, Dystonia
Interventions: NeuroStar TMS therapy, Sham NeuroStar TMS therapy, Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS), Craniocervical Dystonia Questionnaire (CDQ-24), Cerebellar-brain Inhibition (CBI), Botulinum toxin injections; Device · Other · Procedure
Lead sponsor: University of Florida; Other
Eligibility: 30 Years to 75 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2021
U.S. locations: 2
States / cities: Gainesville, Florida

Conditions: ADHD
Interventions: Use of Noise Cancelling Headphones; Other
Lead sponsor: Duke University; Other
Eligibility: 6 Years to 17 Years
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Sleep Apnea Syndromes
Interventions: Antioxidant cocktail; Drug
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 20 Years to 40 Years
Enrollment: 63 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Postoperative Complications, Plastic Surgery
Interventions: Photobiomodulation; Device
Lead sponsor: Elixir MD Inc; Industry
Eligibility: 18 Years and older
Enrollment: 148 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Brain Injuries, Traumatic, Brain Injuries, Acute, TBI (Traumatic Brain Injury)
Interventions: Placebo Infusion, Autologous BMMNC Infusion; Biological
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years to 55 Years
Enrollment: 37 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2025
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Nightmare, Insomnia, PTSD, TBI, Sleep Disorder (Disorder), REM Behavior Disorder
Interventions: NightWare smartwatch configured to detect physiological signs of sympathetic activation during sleep, such as heart-rate spikes and movement patterns., Sham (No Treatment); Device
Lead sponsor: Uniformed Services University of the Health Sciences; Federal
Eligibility: 18 Years to 62 Years
Enrollment: 180 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 2
States / cities: Bethesda, Maryland • Minneapolis, Minnesota

Conditions: Assessment of Hip Strength, Range of Motion, EMG Activation, and Landing Mechanics in Healthy Subjects, Healthy Adult Subjects
Interventions: Hip Bump Manipulation, Sham (No Treatment); Procedure
Lead sponsor: Dominican University New York; Other
Eligibility: 18 Years to 45 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Orangeburg, New York

Search by objective public record fields.

Neuromuscular Intervention Targeted to Mechanisms of ACL Load in Female Athletes

Singing and Cardiovascular Health in Older Adults

The Effect of Facial Effleurage on Acute Rhinosinusitis

The Effects of Cognitive Behavioral Therapy and Transcranial Current Stimulation (tDCS) on Chronic Lower Back Pain

tVNS During Motor Training in Older Adults

Reclaim Deep Brain Stimulation Clinical Study for Treatment-Resistant Depression

Using EEG Operant Conditioning to Improve Trait Self-Control and Promote Healthy Behavior

Brief ROC Training Effects on Alcohol Drinking

Repetitive Transcranial Magnetic Stimulation for Post-concussion Headaches

Effects of a Thoracic Manipulation on Hip Adductor, Extensor, and Latissimus Dorsi Force in Those With Adductor Weakness

Effects of Osteopathic Manipulative Treatment and Bio Electro-Magnetic Regulation Therapy on Neck Pain in Adults

Snacks, Smiles and Taste Preferences

Safe and Timely Antithrombotic Removal - Direct Oral Anticoagulants Apixaban & Rivaroxaban (STAR-D)

Efficacy of AposTherapy® in Knee OA

The Effect of Brain Stimulation (tDCS) in Food Cravings Control in Overweight/Obese Women

The Effects of Energy Healing in Fibromyalgia

Electro-acupuncture (EA) in Children Undergoing Procedures for Congenital Heart Defects.

rTMS and Botulinum Toxin in Primary Cervical Dystonia

Effects of Noise Cancelling Headphones on Neurocognitive and Academic Outcomes in ADHD

Respiratory and Autonomic Plasticity Following Intermittent Hypoxia

ELIXIR MDTM Satisfaction Clinical Trial

Autologous Stem Cell Study for Adult TBI (Phase 2b)

INSIGHT: Insomnia, Nightmares, and Sympathetic Hyperactivity Intervention

Effects of Hip Bump Manipulation Versus Sham Treatment in Healthy Adults