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ClinicalTrials.gov public records Last synced Nov 6, 2026, 3:13 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1009–1032 of 1,170 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sham Control Group Clear all

Conditions: Knee Osteoarthritis, Knee Osteoarthritis (Knee OA), Knee Osteoarthritis (OA)
Interventions: Genicular Artery Embolization, Lipiodol, Simple angiogram; Procedure · Device
Lead sponsor: University of Utah; Other
Eligibility: 40 Years to 80 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Pain Syndrome, Pain Management
Interventions: B Braun HNS 12 nerve stimulator, B Braun HNS 12 nerve stimulator sham control; Device
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Stanford, California

Conditions: Total Knee Arthroplasty (Postoperative Pain), Total Hip Arthroplasty (Postoperative Pain)
Interventions: Transcranial Direct Current Stimulation, Cognitive-Behavioral (CB) intervention; Device · Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 90 Years
Enrollment: 106 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Fibromyalgia, Chronic Pain, Depression
Interventions: rTMS, Sham rTMS; Device
Lead sponsor: University of Washington; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Contrast-induced Acute Kidney Injury
Interventions: RIPC, Sham-RIPC; Device
Lead sponsor: Oladipupo Olafiranye, MD, MS; Other
Eligibility: 18 Years and older
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 2
States / cities: Pittsburgh, Pennsylvania

Conditions: Hip Injuries
Interventions: Ropivacaine, Normal Saline Sham Injection, General Anesthesia; Drug · Other · Procedure
Lead sponsor: Georgetown University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Bronchopulmonary Dysplasia
Interventions: Minimally invasive surfactant therapy, Continuation on CPAP; Device · Other
Lead sponsor: Menzies Institute for Medical Research; Other
Eligibility: 1 Minute to 6 Hours
Enrollment: 486 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2022
U.S. locations: 5
States / cities: New Haven, Connecticut • Honolulu, Hawaii • Evanston, Illinois + 2 more

Conditions: Brain Injuries, Traumatic, Brain Injuries, Acute, TBI (Traumatic Brain Injury)
Interventions: Placebo Infusion, Autologous BMMNC Infusion; Biological
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years to 55 Years
Enrollment: 37 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2025
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Ankle Fracture, Calcaneus Fracture, Talus Fracture, Pilon Fracture
Interventions: Manual Therapy Group, Control Group; Other
Lead sponsor: Intermountain Health Care, Inc.; Other
Eligibility: 18 Years to 70 Years
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Heart Failure With Normal Ejection Fraction
Interventions: low level transcutaneous vagus nerve stimulation; Device
Lead sponsor: University of Oklahoma; Other
Eligibility: 21 Years to 90 Years
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Oklahoma City, Oklahoma

Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: Leg heat therapy, Leg sham therapy; Device
Lead sponsor: Indiana University; Other
Eligibility: 18 Years and older
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 2
States / cities: Indianapolis, Indiana

Conditions: Stress Urinary Incontinence
Interventions: Vesair Balloon, Sham balloon placement; Device · Other
Lead sponsor: Solace Therapeutics, Inc.; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 158 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 25
States / cities: Phoenix, Arizona • San Diego, California • Temecula, California + 22 more

Conditions: Obsessive Compulsive Disorder (OCD)
Interventions: Low Intensity Focused Ultrasound; Device
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 60 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: OSA, SCI/D, Upper Airway Exercise
Interventions: UA and RMT, Sham exercise; Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 89 Years
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Premature Birth, Stress
Interventions: massage therapy, Sham; Other
Lead sponsor: National Center for Complementary and Integrative Health (NCCIH); NIH
Eligibility: 28 Weeks to 33 Weeks
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2009
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Sweet Taste Perception
Interventions: Low sugar diet, Sham diet manipulation; Other
Lead sponsor: Monell Chemical Senses Center; Other
Eligibility: 18 Years to 60 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2010
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Ileus
Interventions: Acupuncture, Sham acupuncture; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 89 Years
Enrollment: 107 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 2
States / cities: Jacksonville, Florida • Rochester, Minnesota

Conditions: Nicotine Dependence
Interventions: Transcranial Direct Current Stimulation, sham, Nicotine patch, Placebo patch, Varenicline Pill, Placebo pill, Motivational Interviewing; Device · Drug · Behavioral
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 65 Years
Enrollment: 112 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2020
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Pupillary Response
Interventions: Transcutaneous Auricular Vagal Nerve Stimulation (taVNS), Sham Stimulation; Procedure
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 65 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: New York, New York

Conditions: COPD, Chronic Obstructive Pulmonary Disease
Interventions: Active HEPA Air Cleaner, Motivational interviewing, Sham Air Cleaner; Device · Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 40 Years and older
Enrollment: 144 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Achilles Tendinopathy
Interventions: Blood Flow Restriction Training, Sham Blood Flow Restriction Training, Eccentric Exercise; Other
Lead sponsor: Womack Army Medical Center; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Fort Bragg, North Carolina

Conditions: Childbirth
Interventions: Materna Prep Device, Sham Control; Device
Lead sponsor: Materna Medical; Industry
Eligibility: 18 Years and older · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014
U.S. locations: 1
States / cities: Mountain View, California

Conditions: Weight Loss, Appetite Loss
Interventions: tDCS, Shame- No current; Device
Lead sponsor: University at Buffalo; Other
Eligibility: 18 Years to 80 Years
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Tinnitus
Interventions: VNS Treatment, VNS Control; Device
Lead sponsor: MicroTransponder Inc.; Industry
Eligibility: 22 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 3
States / cities: Iowa City, Iowa • Buffalo, New York • Dallas, Texas

Search by objective public record fields.

Genicular Artery Embolization for Reducing Pain in Medically Refractory Symptomatic Knee Osteoarthritis

Peripheral Neurostimulation for Nerve Block Placement

Effects of tDCS Combined With CBI on Postsurgical Pain

Transcranial Magnetic Stimulation for Treating Women With Chronic Widespread Pain

Biochemical Effects of Remote Ischemic Pre-Conditioning on Contrast-induced Acute Kidney Injury

Use of Regional Anesthesia in Hip Arthroscopy

OPTIMIST-A Trial: Minimally-invasive Surfactant Therapy in Preterm Infants 25-28 Weeks Gestation on CPAP

Autologous Stem Cell Study for Adult TBI (Phase 2b)

Manual Therapy After Ankle/Hindfoot Fractures

Neuromodulation to Treat Patients With Heart Failure With Preserved Ejection Fraction

Leg Heat Therapy in Heart Failure With Preserved Ejection Fraction

Vesair Clinical Trial

OCD LIFU Target Engagement

Novel by Upper Airway Respiratory Muscle Training to Treat OSA in Chronic SCI

Effects of Massage on the Immune System of Preterm Infants

The Effect of Dietary Sugar Consumption on Sweet Taste Perception

Acupuncture and Post-Operative Ileus

Nicotine Withdrawal Symptoms and Smoking Relapse

taVNS on Pupillary Response and Perceptual Learning

Motivational Interviewing and Air Cleaners for Smokers With COPD (MOVE COPD)

Efficacy of BFR Training Combined With Eccentric Exercise as Assessed by SWE in Subjects With Chronic AT

A Clinical Phase II Study of the Materna Device to Shorten Delivery Time During Childbirth

Role of Transcranial Direct Current Stimulation in Appetite and Weight Control

Vagus Nerve Stimulation (VNS) Paired With Tones for Tinnitus