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ClinicalTrials.gov public records Last synced Nov 6, 2026, 4:13 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1033–1056 of 1,170 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sham Control Group Clear all

Conditions: Parkinson's
Interventions: rTMS, Sham TMS; Device
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 45 Years to 90 Years
Enrollment: 107 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Chronic Pain, Opioid Use, Adductor Canal Block, Total Knee Arthroplasty
Interventions: ambIT pump with catheter, ambIT pump with sham catheter; Device
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 18 Years to 75 Years
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Sudden Cardiac Death, Prolonged QTc Interval
Interventions: EC with nicotine, EC without nicotine, control, TC with nicotine (own brand), research TC with very low level nicotine; Other
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 21 Years to 45 Years
Enrollment: 110 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Postoperative Pain After Uterine Fibroid Embolization, Uterine Fibroids (UF), Uterine Fibroids, Pelvic Pain, Pain Management
Interventions: TUNES (Transmucosal Uterosacral Electrical Stimulation), Sham TUNES Device; Device
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 28 Years to 52 Years · Female only
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Alzheimer Disease, Alzheimer Dementia
Interventions: GENUS device (Active Settings), GENUS device (Sham Settings); Device
Lead sponsor: Massachusetts Institute of Technology; Other
Eligibility: 50 Years to 100 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2027
U.S. locations: 1
States / cities: Cambridge, Massachusetts

Conditions: Traumatic Brain Injury
Interventions: Acupuncture, Sham Acupuncture; Device
Lead sponsor: AOMA Graduate School of Integrative Medicine; Other
Eligibility: 18 Years to 50 Years
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Sleep, Fatigue, Anxiety, Cancer, Depression
Interventions: Melatonin, Placebo for Melatonin, Methylphenidate; Drug · Other
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 169 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Plantar Fascitis
Interventions: Local Steroid Injection into the plantar heel, Ultrasound Guided Injection, Anatomical Guided injection; Procedure
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 62 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2026
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Restless Legs Syndrome
Interventions: Noctrix Health NPNS device v1.0 - Active, Noctrix Health NPNS device v1.0 - Sham; Device
Lead sponsor: Noctrix Health, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 43 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 3
States / cities: Downey, California • Menlo Park, California • San Ramon, California

Conditions: Chronic Obstructive Pulmonary Disease, Muscle Weakness
Interventions: Cholecalciferol, Laboratory Biomarker Analysis, Multivitamin, Placebo, Questionnaire Administration; Dietary Supplement · Other
Lead sponsor: Roswell Park Cancer Institute; Other
Eligibility: 50 Years and older
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Cystoid Macular Edema
Interventions: Pegaptanib Sodium, Control; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Injury, Inflammation
Interventions: dicreatinol sulfate, placebo sugar pill; Dietary Supplement · Drug
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 25 Years
Enrollment: 42 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Muscular Atrophy, Spinal
Interventions: Nusinersen; Drug
Lead sponsor: Biogen; Industry
Eligibility: 7 Days and older
Enrollment: 145 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 7
States / cities: Palo Alto, California • Aurora, Colorado • Chicago, Illinois + 4 more

Conditions: Arterial Stiffness
Interventions: E-cigarette, Nicotine 0%, Menthol Inhalant Product; Drug
Lead sponsor: University of Texas at Austin; Other
Eligibility: 20 Years to 30 Years
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Psychology, Social, Inflammation, Defeat, Social, Interaction, Social
Interventions: Influenza vaccine, Placebo; Biological
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 35 Years
Enrollment: 104 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 2
States / cities: Chapel Hill, North Carolina

Conditions: Hidradenitis Suppurativa (HS)
Interventions: AviClear Lase Treatment, Sham (No Treatment); Device
Lead sponsor: Wynn Medical Center; Other
Eligibility: 18 Years to 60 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Rosemead, California

Conditions: Hypertension, Pure Autonomic Failure, Multiple System Atrophy, Autonomic Failure
Interventions: Heating pad, Sham control; Other
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years to 80 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2026
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: COPD, COPD - Chronic Obstructive Pulmonary Disease
Interventions: Activated ROAM System with User Feedback, Sham Comparator; Device
Lead sponsor: Barron Associates, Inc.; Industry
Eligibility: 21 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Psychiatric Disorders, Anxiety Disorders
Interventions: Gaze-Contingent Music Reward Therapy; Behavioral
Lead sponsor: National Institute of Mental Health (NIMH); NIH
Eligibility: 8 Years to 17 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Meibomian Gland Dysfunction, Evaporative Dry Eye
Interventions: Dexamethasone, 0.4mg, Prednisone acetate, Control; Drug · Other
Lead sponsor: Warrenville Eyecare; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Warrenville, Illinois

Conditions: Spinal Cord Injury, Neurogenic Bladder
Interventions: Transcutaneous Tibial Nerve Stimulation, Control; Device
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years to 65 Years
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Traumatic Brain Injury With Brief Loss of Consciousness, Post-Concussion Syndrome
Interventions: Hyperbaric oxygen (HBO2) at 1.5 atms, Sham control 1.2 atms; Drug
Lead sponsor: U.S. Army Medical Research and Development Command; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 71 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 5
States / cities: Colorado Springs, Colorado • Fort Carson, Colorado • Jacksonville, North Carolina + 2 more

Conditions: Refractory Angina
Interventions: Arm 1: treatment with Shockwave Reducer, Arm 2 (control): Implantation procedure with no device implanted, Arm 3 (unblinded, non-randomized): Single arm registry; Device · Other
Lead sponsor: Shockwave Medical, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 380 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2032
U.S. locations: 72
States / cities: Phoenix, Arizona • Scottsdale, Arizona • Tucson, Arizona + 57 more

Conditions: TBI (Traumatic Brain Injury), Headache, Depression
Interventions: Active rTMS, Headache Management Therapy, Sham rTMS, Headache Education Control; Device · Behavioral
Lead sponsor: Veterans Medical Research Foundation; Other
Eligibility: 18 Years to 65 Years
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: San Diego, California

Search by objective public record fields.

Cognitive Dysfunction In Parkinson's

Enhanced Recovery After Major Surgery and Chronic Pain for Total Knee Arthroplasty

Smoking and Ventricular Repolarization

Transmucosal Uterosacral Electrical Stimulation for Pelvic Pain Relief

Daily Light and Sound Stimulation to Improve Brain Functions in Alzheimer's Disease

Translational Research Examining Acupuncture Treatment in Traumatic Brain Injury

Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer

Plantar Fasciitis Randomized Clinical Control Trial

Noninvasive Peripheral Nerve Stimulation for Restless Legs Syndrome

Cholecalciferol Supplementation in Strengthening Inspiratory Muscles in Cholecalciferol-Deficient Patients With Chronic Obstructive Pulmonary Disease

The Effect of Macugen in Patients With Chronic, Post-Operative Cystoid Macular Edema

Nutritional Supplement, Eccentric Exercise and Recovery

Study of Nusinersen (BIIB058) in Participants With Spinal Muscular Atrophy

Vascular Effects of a Single Bout of Electronic Cigarette Use

Body and Social Behavior

1726-nm Laser for Acne Inversa (Hidradenitis Suppurativa)

Overnight Trials With Heat Stress in Autonomic Failure Patients With Supine Hypertension

Respiratory Oxygen Adherence Monitor for Chronic Obstructive Pulmonary Disease Patients

Gaze-Contingent Music Therapy Augmentation of CBT for Pediatric Anxiety

Dextenza With ILUX for Treatment of MGD

The Effects Upon the Bladder of Transcutaneous Tibial Nerve Stimulation in Acute Traumatic Spinal Cord Injury

mTBI Mechanisms of Action of HBO2 for Persistent Post-Concussive Symptoms

Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II

Combined Transcranial Magnetic Stimulation and Therapy for MTBI Related Headaches