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ClinicalTrials.gov public records Last synced Nov 8, 2026, 8:05 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1153–1171 of 1,171 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Sham Control Group Clear all

Conditions: Plaque
Interventions: 3M™ Oral Rinse, Vehicle Control Oral Rinse, PerioShield™ Oral Health Rinse, Water; Device · Other
Lead sponsor: Solventum US LLC; Industry
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Loma Linda, California

Conditions: Legal Abortion With Complication, Pain
Interventions: Paracervical Block, Sham Paracervical Block; Procedure
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 18 Years to 60 Years · Female only
Enrollment: 121 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Low Back Pain
Interventions: foot orthotics, Sham foot orthotic; Device
Lead sponsor: Logan College of Chiropractic; Other
Eligibility: 18 Years and older
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Chesterfield, Missouri

Conditions: Pain, Amputation
Interventions: 10 mL 2% lidocaine, 10 mL preservative free saline; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Heart Failure
Interventions: Splanchnic nerve block, Sham-control procedure; Device · Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Overweight/Obese Population
Interventions: Modified Go/No-Go Task; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 20 Years to 55 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Erectile Dysfunction
Interventions: Shockwave therapy, Sham shockwave therapy; Device · Other
Lead sponsor: University of Miami; Other
Eligibility: 30 Years to 70 Years · Male only
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Obesity
Interventions: GI Sleeve Implantable weight loss device (EndoBarrier), Sham Procedure; Device · Procedure
Lead sponsor: Morphic Medical Inc.; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 4
States / cities: Weston, Florida • Burlington, Massachusetts • Lebanon, New Hampshire + 1 more

Conditions: Persistent Post-concussive Syndrome, Concussion Post Syndrome
Interventions: Hyperbaric oxygen at 1.5 ATA, Sham treatment; Drug
Lead sponsor: Essentia Health; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Fargo, North Dakota

Conditions: Mobility Limitation
Interventions: Dry Needling, Sham Needling; Procedure · Other
Lead sponsor: Keller Army Community Hospital; Federal
Eligibility: 18 Years to 40 Years
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: West Point, New York

Conditions: End Stage Kidney Disease, Depressive Symptoms
Interventions: Joviality(TM), Inert Virtual Reality; Behavioral · Other
Lead sponsor: University of Illinois at Urbana-Champaign; Other
Eligibility: 21 Years and older
Enrollment: 61 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 3
States / cities: Chicago, Illinois

Conditions: Abortion Late, Pain
Interventions: Local anesthetic for tenaculum placement, Sham, Paracervical Block, Dilator Placement, Post-procedural assessment, Preprocedural pain control; Procedure · Behavioral · Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older · Female only
Enrollment: 14 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015
U.S. locations: 2
States / cities: San Diego, California

Conditions: Hearing Disability, Depression, Mobility Disability
Interventions: Sham Digital Program - General health education and interactive quizzes unrelated to depression or CBT., Toivoa-002 - A digital Cognitive Behavioral Therapy program combined with NBHWC-certified coaching.; Device
Lead sponsor: Toivoa Inc; Industry
Eligibility: 22 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 4
States / cities: Dover, Delaware • East Orange, New Jersey • Cleveland, Ohio + 1 more

Conditions: Dysphonia
Interventions: Online Voice quality education module, Vocal hygiene module; Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 100 Years
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: New York, New York

Conditions: BPH (Benign Prostatic Hyperplasia), Lower Urinary Tract Symptoms (LUTS)
Interventions: Zenflow Spring System, Sham Procedure; Device
Lead sponsor: Zenflow, Inc.; Industry
Eligibility: 45 Years and older · Male only
Enrollment: 279 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 7
States / cities: Los Angeles, California • Glenview, Illinois • Las Vegas, Nevada + 3 more

Conditions: Fibromyalgia
Interventions: Alpha-stim; Device
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 20 Years to 60 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Decatur, Georgia

Conditions: Osteoarthritis of the Knee
Interventions: Autologous bone marrow aspirate concentrate (BMAC), Corticosteroid injections, Crossover Autologous bone marrow aspirate concentrate (BMAC); Other · Drug
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years to 70 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2028
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Neuropathic Pain, Chronic Pain
Interventions: Ultrasound, Sham (No Treatment); Device
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Stanford, California

Conditions: Sickle Cell Disease, Chronic Kidney Diseases, Systemic Lupus Erythematosus, Childhood Cancer, Inflammatory Bowel Diseases, Stem Cell Transplant, Organ Transplant, Diabetes Mellitus, Type 1, Cystic Fibrosis
Interventions: PiCASO Intervention Group, Sham Comparator: Attention Control Group; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 16 Years to 22 Years
Enrollment: 222 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Durham, North Carolina

Search by objective public record fields.

A Clinical Study to Evaluate Effects of an Oral Rinse on Plaque and Gingivitis

Paracervical Block for Pain Control in First Trimester Abortion

Duration of Spinal Manipulation Effects as Influenced by Orthotics

Sciatic Block in Contralateral Limb Phantom and Residual Limb Pain

Splanchnic X: Splanchnic Nerve Block in Heart Failure With Reduced Ejection Fraction

Healthy Behaviors Learning Task and Sleep

Low Intensity Shockwaves Therapy for the Treatment of Erectile Dysfunction. 12- Month Follow-Up

Multi-Center Pre-Bariatric Weight Loss Study

Hyperbaric Oxygen Effects on Persistent Post-concussive Symptoms

Dry Needling and Stretching vs. Stretching Alone on Hamstring Flexibility in Patients With Knee Pain

Virtual Reality in Hemodialysis to Improve Psychological Well-being

Paracervical Block for Pain Control With Osmotic Dilator Placement

Reduction of Depression Through Dual Treatment: Digital CBT & NBHWC Coaching

Assessing the Effects of Patient Self-Rating of Voice Quality on Voice Therapy Attendance and Outcomes

Safety and Effectiveness Study of the Zenflow Spring System

Randomized Controlled Trial of CES for Fibromyalgia

Bone Marrow Aspirate Concentrate (BMAC) vs Corticosteroid Injection

Ultrasound for Peripheral Nerve Modulation

Peer i-Coaching for Activated Self-Management Optimization in Adolescents and Young Adults With Chronic Conditions