Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.

Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 22, 2026, 4:36 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 54 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Sham Hypoxia Clear all
Active, not recruiting Not applicable Interventional

Acute Intermittent Hypoxia on Leg Function Following Spinal Cord Injury

NCT02274116
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
SHAM - Intermittent Room Air - room air mixture, AIH - Intermittent Hypoxia - hypoxia air mixture
Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2027
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 20, 2026 · Synced Oct 22, 2026, 4:36 AM EDT
Recruiting Not applicable Interventional

Hypoxia Pathways for Early Recovery After Spinal Cord Injury

NCT07002437
View directory record Official record
Conditions
Spinal Cord Injuries (SCI)
Interventions
Augmented Acute Intermittent Hypoxia (aAIH), Acute Intermittent Hypercapnic-Hypoxia (AIHH), Sham AIH
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 70 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 3, 2025 · Synced Oct 22, 2026, 4:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Acute Intermittent Hypoxia on Sensory Function in Healthy Adults

NCT03283072
View directory record Official record
Conditions
Sensitivity
Interventions
Intervention 1, Intervention 2, Intervention 3, Intervention 4 (sham)
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 40 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 21, 2023 · Synced Oct 22, 2026, 4:36 AM EDT
Completed Not applicable Interventional

Iron Absorption in The Low Oxygen Exposure and Weight Status (LOWS) Study

NCT07542873
View directory record Official record
Conditions
Obesity (Disorder)
Interventions
Normobaric hypoxia (NH), Normobaric normoxia (NN)
Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
22 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 22, 2026, 4:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Improving Human Cerebrovascular Function Using Acute Intermittent Hypoxia

NCT05164705
View directory record Official record
Conditions
Healthy Brain Perfusion
Interventions
Acute Intermittent Hypoxia, Sham Acute Intermittent Hypoxia
Other
Lead sponsor
Northwestern University
Other
Eligibility
21 Years to 50 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 22, 2026, 4:36 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Daily Low Oxygen Exposure and Weight Status

NCT04801810
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Normobaric hypoxia, Normobaric normoxia
Other
Lead sponsor
Florida State University
Other
Eligibility
20 Years to 50 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Apr 1, 2022 · Synced Oct 22, 2026, 4:36 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Respiratory and Autonomic Plasticity Following Intermittent Hypoxia

NCT00860743
View directory record Official record
Conditions
Sleep Apnea Syndromes
Interventions
Antioxidant cocktail
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
20 Years to 40 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 1, 2017 · Synced Oct 22, 2026, 4:36 AM EDT
Completed Not applicable Interventional

FLO2 for Recovery After SCI

NCT03833674
View directory record Official record
Conditions
Spinal Cord Injury (SCI)
Interventions
Daily AIH Block, Sham dAIH Block, Respiratory Strength Training Block, AIH + Strength Training Block
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 70 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 29, 2024 · Synced Oct 22, 2026, 4:36 AM EDT
Active, not recruiting Not applicable Interventional

A Multi-Center Clinical Trial in Individuals With Spinal Cord Injury

NCT03644277
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Acute Intermitted Hypoxia, Massed Practise, Rapael Glove
Other · Procedure
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 75 Years
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
3
States / cities
Chicago, Illinois • East Hanover, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 24, 2025 · Synced Oct 22, 2026, 4:36 AM EDT
Completed Not applicable Interventional

Peripheral Nerve Stimulation to Reduce Hypoxic Events

NCT02554110
View directory record Official record
Conditions
Apnea, Hypoventilation, Hypoxemia
Interventions
Stimulator active device, Stimulator sham Device
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 15, 2018 · Synced Oct 22, 2026, 4:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Acute Intermittent Hypoxia on Motor Learning

NCT05341466
View directory record Official record
Conditions
Incomplete Spinal Cord Injury
Interventions
Acute Intermittent Hypoxia, SHAM Acute Intermittent Hypoxia
Other
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years to 70 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
2
States / cities
Aurora, Colorado • Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated May 14, 2025 · Synced Oct 22, 2026, 4:36 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Breathing Training and Nitrate on Exercise at Simulated Altitude

NCT07216755
View directory record Official record
Conditions
Healthy Adults, Mechanical Ventilation Dependence, Hypoxia, Exercise Training, Exercise Intolerance, Dietary Supplement, Nitrate Supplementation, Inspiratory Muscle Training
Interventions
Respiratory Muscle Training (RMT), Sham Respiratory Muscle Training, Dietary Supplement: Beetroot Juice Concentrate, placebo beverage
Device · Dietary Supplement
Lead sponsor
Embry-Riddle Aeronautical University
Other
Eligibility
18 Years to 40 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Daytona Beach, Florida
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced Oct 22, 2026, 4:36 AM EDT
Recruiting Not applicable Interventional

Dose Optimization Study of Acute Intermittent Hypoxia in Spinal Cord Injury

NCT07739992
View directory record Official record
Conditions
Spinal Cord Injuries (SCI)
Interventions
Sham AIH, Acute Intermittent Hypoxia (AIH) 15, Acute Intermittent Hypoxia (AIH) 23
Other
Lead sponsor
Milap Sandhu
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 22, 2026, 4:36 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Repetitive Acute Intermittent Hypoxia for Spinal Cord Repair

NCT03433599
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Repeated exposure to acute Intermittent Hypoxia (rAIH), Normal Room Air, Upper-limb Training by Research Staff, Lower-limb Training by Research Staff
Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 30, 2022 · Synced Oct 22, 2026, 4:36 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Treatment of Sleep Apnea in Patients With Cervical Spinal Cord Injury

NCT02922894
View directory record Official record
Conditions
Sleep Apnea, Spinal Cord Injury
Interventions
Acute episodic hypoxia, Supplemental oxygen, Trazodone, Placebo, Sham
Procedure · Drug
Lead sponsor
John D. Dingell VA Medical Center
Federal
Eligibility
18 Years to 89 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 22, 2026, 4:36 AM EDT
Completed Not applicable Interventional

Acute Intermittent Hypoxia to Improve Airway Protection in Chronic Traumatic Brain Injury

NCT06520358
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Acute Intermittent Hypoxia (AIH), Task specific Airway Protection Training, Sham AIH
Other · Behavioral
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 9, 2026 · Synced Oct 22, 2026, 4:36 AM EDT
Completed Not applicable Interventional Results available

SCI Acute Intermittent Hypoxia and Non-Invasive Spinal Stimulation Combined With Gait Training

NCT03922802
View directory record Official record
Conditions
Spinal Cord Injuries, Spinal Cord Diseases
Interventions
Acute Intermittent Hypoxia + Non Invasive Spinal Cord Stimulation + Gait Training, Sham Acute Intermittent Hypoxia + Non Invasive Spinal Cord Stimulation + Gait Training, Sham Acute Intermittent Hypoxia + Sham Non Invasive Spinal Cord Stimulation + Gait Training
Device · Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Oct 22, 2026, 4:36 AM EDT
Completed Not applicable Interventional

Acute Intermittent Hypoxia in Persons With Multiple Sclerosis

NCT04280484
View directory record Official record
Conditions
Multiple Sclerosis, Relapsing-Remitting
Interventions
Intermittent Hypoxia, Sham Hypoxia
Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 24, 2020 · Synced Oct 22, 2026, 4:36 AM EDT
Completed Not applicable Interventional

Intermittent Hypoxia Paired with High Intensity Training in Brain Injury

NCT04472442
View directory record Official record
Conditions
Brain Injuries
Interventions
Intermittent hypoxia, Sham hypoxia
Procedure
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 85 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 17, 2024 · Synced Oct 22, 2026, 4:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Enhancing Cognition in Older Adults With Intermittent Hypoxia and Cognitive Training

NCT03957213
View directory record Official record
Conditions
Aging
Interventions
Acute Intermittent Hypoxia, Computerized Cognitive Training
Device · Behavioral
Lead sponsor
University of Florida
Other
Eligibility
65 Years to 89 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 4, 2022 · Synced Oct 22, 2026, 4:36 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Low Oxygen Exposure and Weight Status

NCT05289310
View directory record Official record
Conditions
Obesity
Interventions
Normobaric hypoxia (NH), Normobaric normoxia (NN)
Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
22 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 22, 2026, 4:36 AM EDT
Active, not recruiting Not applicable Interventional

Project Tendura: The Impact of Blood Flow Restriction Resistance Training (BFR-RT) in Patients With Achilles Tendon Rupture (ATR) Repair

NCT07498166
View directory record Official record
Conditions
Achilles Tendon Rupture, Blood Flow Restriction Therapy, Achilles Tendon Repairs/Reconstructions, Dynamic Blood Flow Restriction
Interventions
Blood Flow Restriction Resistance Training (BFR-RT), Sham Blood Flow Restriction, Standard Physical Therapy
Device · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Oct 22, 2026, 4:36 AM EDT
Completed Early Phase 1 Interventional

Effect of a Novel Intervention Using Daily Intermittent Hypoxia and High Intensity Training on Upper Limb Function in Individuals With Spinal Cord Injury

NCT03643770
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Upper extremity training/Armeo Spring
Combination Product
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 75 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Oct 22, 2026, 4:36 AM EDT
Recruiting Not applicable Interventional

Effects of Acute Intermittent Hypoxia on Neuroplasticity in MS

NCT06390930
View directory record Official record
Conditions
Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting, Multiple Sclerosis, Secondary Progressive
Interventions
Acute Intermittent Hypoxia, Sham Acute Intermittent Hypoxia
Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 75 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Oct 22, 2026, 4:36 AM EDT