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ClinicalTrials.gov public records Last synced Oct 17, 2026, 1:49 PM EDT

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Showing 1–24 of 45 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Sham Osteopathic Manipulation Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

The Use of Osteopathic Medical Manipulation to Decrease the Incidence and Severity of Post-Operative Sore Throat

NCT03720301
View directory record Official record
Conditions
Pharyngitis, Dysphonia
Interventions
Osteopathic Manipulation Treatment, Sham
Procedure
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years and older
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 25, 2018 · Synced Oct 17, 2026, 1:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Osteopathic Manipulative Therapy on Hip Range of Motion

NCT06644989
View directory record Official record
Conditions
Runners
Interventions
Spencer Technique, Sham (No Treatment)
Procedure · Other
Lead sponsor
Lake Erie College of Osteopathic Medicine
Other
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Bradenton, Florida
Source: ClinicalTrials.gov public record
Updated Oct 24, 2024 · Synced Oct 17, 2026, 1:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Osteopathic Manipulative Therapy Effects on Prolonged Post-COVID Olfactory Dysfunction

NCT05112887
View directory record Official record
Conditions
COVID-19 Lower Respiratory Infection, SARS-CoV2 Infection
Interventions
Osteopathic Manipulative Therapy
Other
Lead sponsor
Ohio University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Dublin, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 9, 2021 · Synced Oct 17, 2026, 1:49 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Will the Use of Osteopathic Manipulative Treatments Help Alleviate Headache Pain

NCT01704625
View directory record Official record
Conditions
Headache
Interventions
Osteopathic Manipulative Treatment, Sham Osteopathic Manipulative Treatment
Procedure
Lead sponsor
Good Samaritan Hospital Medical Center, New York
Other
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
West Islip, New York
Source: ClinicalTrials.gov public record
Updated Oct 11, 2012 · Synced Oct 17, 2026, 1:49 PM EDT
Not listed Not applicable Interventional

Effects Of Osteopathic Manipulative Medicine(OMM) On Lower Extremity Muscle Characteristics In Parkinson's Disease(PD) Patients

NCT05884944
View directory record Official record
Conditions
Parkinson Disease, Osteopathy in Diseases Classified Elsewhere
Interventions
Sham- Light touch, not reaching restrictive barrier, Experimental: Interventional Group- OMM- Muscle energy
Procedure
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Aug 7, 2024 · Synced Oct 17, 2026, 1:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Osteopathic Manipulative Treatment and Bio Electro-Magnetic Regulation Therapy on Low Back Pain in Adults.

NCT04704375
View directory record Official record
Conditions
Musculoskeletal Pain
Interventions
Bio Electro-Magnetic Regulation (BEMER) Therapy, OMT (osteopathic manipulative treatment), Light touch
Device · Procedure
Lead sponsor
Lake Erie College of Osteopathic Medicine
Other
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Bradenton, Florida
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 17, 2026, 1:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Osteopathic Manipulation on Circulating Immune Markers

NCT07622966
View directory record Official record
Conditions
Healthy Adult Participants, Osteopathic Manipulative Treatment (OMT)
Interventions
Osteopathic Manipulative Treatment (OMT), Sham Comparator
Other
Lead sponsor
Edward Via Virginia College of Osteopathic Medicine
Other
Eligibility
18 Years to 70 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Monroe, Louisiana
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 17, 2026, 1:49 PM EDT
Completed Not applicable Interventional

Effect of Osteopathic Manipulative Medicine (OMM) on Pulmonary Function and Speech in Parkinson's Disease

NCT01636011
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Osteopathic Manipulative Medicine Treatment, Light Touch sham
Other
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Oct 16, 2017 · Synced Oct 17, 2026, 1:49 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Optimizing Lymphatic Pumping for Influenza Vaccine Responses in Vulnerable Populations

NCT07786467
View directory record Official record
Conditions
No Disease or Condition is Being Directly Studied, The Focus of the Study in Healthy Volunteers
Interventions
Osteopathic manipulation, Sham
Other
Lead sponsor
Lake Erie College of Osteopathic Medicine
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Erie, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Oct 17, 2026, 1:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Alterations in Bioelectric Activity at Acupuncture Points Following CV4 Cranial Manipulation

NCT05190731
View directory record Official record
Conditions
Autonomic Imbalance
Interventions
Osteopathic cranial manipulative medicine, Sham
Other
Lead sponsor
Jan T Hendryx
Other
Eligibility
18 Years to 78 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Erie, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 22, 2022 · Synced Oct 17, 2026, 1:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Echinacea Purpurea and Osteopathy in Children With Recurrent Otitis Media

NCT00689468
View directory record Official record
Conditions
Otitis Media
Interventions
Cranial osteopathic manipulative treatment., Echinacea purpurea, Sham osteopathic manipulative treatment, "Echinacea purpurea" placebo
Procedure · Dietary Supplement
Lead sponsor
University of Arizona
Other
Eligibility
12 Months to 60 Months
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2002
U.S. locations
3
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 3, 2008 · Synced Oct 17, 2026, 1:49 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Physical Exam, Static & Dynamic Ultrasound Assessment, & Treatment of Thoracolumbar Fascia (TLF) Mediated Low Back Pain

NCT06818175
View directory record Official record
Conditions
Low Back Pain, Chronic Low-back Pain, Acute Low Back Pain
Interventions
Ultrsound Guided Hydrodissection of the Thoracolumbar Fascia, Osteopathic Manipulative Treatment (OMT)
Procedure
Lead sponsor
Edward Via Virginia College of Osteopathic Medicine
Other
Eligibility
18 Years to 50 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 17, 2026, 1:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Osteopathic Manipulative Medicine in Pregnancy: Physiologic and Clinical Effects

NCT00426244
View directory record Official record
Conditions
Low Back Pain, Pregnancy
Interventions
Osteopathic Manipulative Treatment, Placebo Ultrasound
Other
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Aug 21, 2018 · Synced Oct 17, 2026, 1:49 PM EDT
Not yet recruiting Not applicable Interventional

Can a Specific OMT Protocol Influence Patient Pain and Associated Analgesia Use for Primary Headache Disorders?

NCT06546462
View directory record Official record
Conditions
Headache Disorders, Headache, Analgesia, Opioid Use, Osteopathy
Interventions
Osteopathic Manipulative Treatment (OMT), Sham Light touch arm
Other
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Mar 17, 2025 · Synced Oct 17, 2026, 1:49 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Investigating the Efficacy of OMT to Recover Olfactory Perception After COVID-19

NCT06766279
View directory record Official record
Conditions
Anosmia
Interventions
Osteopathic Manipulative Treatment, Sham treatment
Procedure
Lead sponsor
Burrell College of Health Sciences
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Las Cruces, New Mexico
Source: ClinicalTrials.gov public record
Updated Jan 9, 2025 · Synced Oct 17, 2026, 1:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Osteopathic Cranial Manipulative Medicine on Visual Function

NCT02728713
View directory record Official record
Conditions
Visual Function
Interventions
Cranial Manipulation, Sham/Placebo
Procedure
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 35 Years
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2005
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Source: ClinicalTrials.gov public record
Updated Apr 5, 2016 · Synced Oct 17, 2026, 1:49 PM EDT
Completed Not applicable Interventional

Effects of Osteopathic Manipulative Therapy on Arrhythmias

NCT04004741
View directory record Official record
Conditions
Cardiac Arrhythmia
Interventions
Osteopathic Manipulative Treatment, Light Touch Therapy
Procedure
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Glen Head, New York
Source: ClinicalTrials.gov public record
Updated Apr 6, 2023 · Synced Oct 17, 2026, 1:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of OMT on Functional Outcomes and Anti-inflammatory Biomarkers in Mild to Moderate Traumatic Brain Injury

NCT03163901
View directory record Official record
Conditions
Vestibular Disorder, Headache, Traumatic Brain Injury
Interventions
Osteopathic Manipulative Treatment
Other
Lead sponsor
Michigan State University
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Mason, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 24, 2020 · Synced Oct 17, 2026, 1:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Tissue Changes Following Thoracic Myofascial Release

NCT06651671
View directory record Official record
Conditions
Myofascial Dysfunction, Myofascial Release
Interventions
Myofascial release, Sham (No Treatment)
Procedure
Lead sponsor
Rowan University
Other
Eligibility
18 Years to 35 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Stratford, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 22, 2024 · Synced Oct 17, 2026, 1:49 PM EDT
Completed Not applicable Interventional

Preventative Osteopathic Manipulative Treatment (OMT) and the Nursing Home Patient

NCT01000142
View directory record Official record
Conditions
General Health Status
Interventions
Osteopathic Manipulative Treatment, Light Touch
Procedure
Lead sponsor
A.T. Still University of Health Sciences
Other
Eligibility
65 Years to 100 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
2
States / cities
Kirksville, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 28, 2018 · Synced Oct 17, 2026, 1:49 PM EDT
Completed Not applicable Interventional

The Effect of OMT on Patients With COPD: Correlating Pulmonary Function Tests With Biochemical Alterations

NCT01582958
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
Osteopathic Manipulative Treatment (OMT), sham omt
Procedure · Other
Lead sponsor
Michigan State University
Other
Eligibility
49 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 8, 2015 · Synced Oct 17, 2026, 1:49 PM EDT
Completed Phase 4 Interventional

Effect of Osteopathic Manipulative Treatment for Patients With Chronic Headache

NCT01332864
View directory record Official record
Conditions
Headache, Cephalgia, Migraine
Interventions
Osteopathic Manipulative Treatment (OMT), Light touch
Procedure
Lead sponsor
Western University of Health Sciences
Other
Eligibility
Not listed
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Pomona, California
Source: ClinicalTrials.gov public record
Updated Feb 13, 2013 · Synced Oct 17, 2026, 1:49 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

The Effect of Osteopathic Manipulative Techniques on Human Tear Composition

NCT07633496
View directory record Official record
Conditions
No Disease or Condition is Being Directly Studied, The Focus of the Study in Healthy Volunteers
Interventions
Osteopathic Manipulative Treatment, Sham
Other
Lead sponsor
Lake Erie College of Osteopathic Medicine
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Erie, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 17, 2026, 1:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of Osteopathic Manipulative Medicine on the Autonomic Nervous System

NCT02193373
View directory record Official record
Conditions
Osteopathic Manual Manipulation of Neurovascular Regulation
Interventions
Osteopathic Manual Medicine, Sham
Other
Lead sponsor
New York Institute of Technology
Other
Eligibility
20 Years to 50 Years
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Jul 5, 2019 · Synced Oct 17, 2026, 1:49 PM EDT