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ClinicalTrials.gov public records Last synced Oct 22, 2026, 1:10 AM EDT

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Showing 49–63 of 63 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Sham Photobiomodulation Clear all
Completed Not applicable Interventional Results available

Study of Photobiomodulation to Treat Dry Age-Related Macular Degeneration (LIGHTSITE III)

NCT04065490
View directory record Official record
Conditions
Dry Age-related Macular Degeneration
Interventions
Valeda Light Delivery System, Valeda Light Delivery System Sham Mode
Device
Lead sponsor
LumiThera, Inc.
Industry
Eligibility
50 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
10
States / cities
Beverly Hills, California • Palo Alto, California • Altamonte Springs, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 22, 2026, 1:10 AM EDT
Completed Phase 1 Interventional

A Study Evaluating the Efficacy of the Vielight Neuro RX Gamma in the Treatment of Post COVID-19 Cognitive Impairment

NCT05857124
View directory record Official record
Conditions
Post COVID-19 Cognitive Impairment
Interventions
Vielight Neuro RX Gamma active device, Vielight Neuro RX Gamma sham device
Device
Lead sponsor
Vielight Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Fullerton, California
Source: ClinicalTrials.gov public record
Updated Jun 15, 2025 · Synced Oct 22, 2026, 1:10 AM EDT
Completed Not applicable Interventional

A Project to Test the Efficacy and Safety of An Innovative Treatment for Opiate Use Disorders.

NCT05995873
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
Sham unilateral transcranial photobiomodulation, transcranial photobiomodulation at 810 nm at 250 mW/cm2 for 4 minutes
Other · Device
Lead sponsor
MindLight, LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Newton Highlands, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 22, 2026, 1:10 AM EDT
Recruiting Not applicable Interventional

Integrated Platform for Measuring and Reducing Symptoms of Autism Spectrum Disorder

NCT06006637
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Cognilum TM: Light Treatment Condition
Device
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
2 Years to 8 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
New York, New York • Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 22, 2026, 1:10 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Evaluating the Technology and Assessing the Biological Effects of Commercially Available PhotoBioModulation Devices

NCT06403644
View directory record Official record
Conditions
Physiological Wellness
Interventions
NovoTHOR XL Photobiomodulation Full Body Light Bed, ARRC LED Photobiomodulation Full Body Light Bed
Device
Lead sponsor
United States Air Force Research Laboratory
Federal
Eligibility
18 Years to 45 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Beavercreek, Ohio
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Oct 22, 2026, 1:10 AM EDT
Recruiting Not applicable Interventional

tPBM in Older Adults With Traumatic Brain Injury

NCT06956404
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Transcranial photobiomodulator (tPBM), Transcranial photobiomodulator (tPBM) in sham mode
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
55 Years to 85 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Oct 22, 2026, 1:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Revitalize Cognition: Near Infrared Stimulation in Older Adults

NCT02582593
View directory record Official record
Conditions
Aging
Interventions
MedX 1116 Rehab Console, Sham MedX 1116 Rehab Console
Device
Lead sponsor
University of Florida
Other
Eligibility
62 Years to 99 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
2
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 19, 2025 · Synced Oct 22, 2026, 1:10 AM EDT
Recruiting Not applicable Interventional

Obstructive Sleep Apnea Therapeutic Intervention for REsiDual Sleepiness

NCT06698809
View directory record Official record
Conditions
Obstructive Sleep Apnea, Sleepiness
Interventions
Active tPBM
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 75 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Oct 22, 2026, 1:10 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Transcranial Photobiomodulation in Anxiety Disorders

NCT07133893
View directory record Official record
Conditions
Symptoms of Anxiety
Interventions
Attention bias assessment and modification, Transcranial photobiomodulation
Behavioral · Device
Lead sponsor
Francisco Gonzalez-Lima, PhD
Other
Eligibility
18 Years to 100 Years
Enrollment
280 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Oct 22, 2026, 1:10 AM EDT
Completed Not applicable Interventional

Efficacy And Safety Of An Innovative Treatment Of Opiate Use Disorders

NCT04340622
View directory record Official record
Conditions
Opioid-use Disorder, Opioid Dependence, Opioid Abuse
Interventions
supra-luminous LED, Sham
Device
Lead sponsor
MindLight, LLC
Industry
Eligibility
18 Years to 70 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
Belmont, Massachusetts • Newton Highlands, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 25, 2021 · Synced Oct 22, 2026, 1:10 AM EDT
Recruiting Not applicable Interventional

Photobiomodulation for Lower Back Pain Post Spinal Fusion and Decompression Surgery

NCT06282770
View directory record Official record
Conditions
Spinal Fusion, Chronic Lower Back Pain
Interventions
Laser Diode Brace, Sham Laser Diode Brace
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 75 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Oct 22, 2026, 1:10 AM EDT
Terminated Not applicable Interventional Results available

Photobiomodulation for the Management of Temporomandibular Disorder Pain

NCT04415281
View directory record Official record
Conditions
Pain Related to TMD
Interventions
THOR® laser system, sham THOR® laser system
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 12, 2023 · Synced Oct 22, 2026, 1:10 AM EDT
Completed Not applicable Interventional

Photobiomodulation Therapy in Persons With Multiple Sclerosis

NCT03691766
View directory record Official record
Conditions
Multiple Sclerosis, Relapsing-Remitting
Interventions
Photobiomodulation Therapy, Placebo
Other
Lead sponsor
Marquette University
Other
Eligibility
20 Years to 60 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 26, 2021 · Synced Oct 22, 2026, 1:10 AM EDT
Recruiting Not applicable Interventional

Photobiomodulation in Head and Neck Cancer-Related Chronic Lymphedema

NCT06837480
View directory record Official record
Conditions
Head and Neck Cancer, Lymphedema of the Head and Neck
Interventions
LTU-904 Portable Laser Therapy Unit (active laser device), LTU-904 Portable Laser Therapy Unit (sham/inactive laser device)
Device
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 22, 2026, 1:10 AM EDT
Recruiting Not applicable Interventional

An Examination of Whether Infrared Light Therapy Can Reduce Stress in People With Epilepsy

NCT07509177
View directory record Official record
Conditions
Epilepsy
Interventions
Photobiomodulation
Other
Lead sponsor
Cynthia Kerson
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
4
States / cities
North Miami, Florida • Cincinnati, Ohio • Warren, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Oct 22, 2026, 1:10 AM EDT