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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Sham Program Clear all
Completed Not applicable Interventional Results available

Nursing Assistant Intervention to Prevent Delirium in Nursing Homes

NCT02994979
View directory record Official record
Conditions
Delirium
Interventions
Delirium-prevention, Sham comparator
Other
Lead sponsor
Jewish Home & Hospital Lifecare System
Other
Eligibility
18 Years and older
Enrollment
219 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 3, 2019 · Synced Sep 2, 2026, 1:51 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Functional Near-Infrared Spectroscopy and Virtual Reality Relaxation Programs for Pain Management in Patients With Cancer

NCT06456411
View directory record Official record
Conditions
Breast Carcinoma, Kidney Carcinoma, Carcinoma
Interventions
Functional Near-Infrared Spectroscopy, Questionnaire Administration, Virtual Technology Intervention, Cold Stimulation
Procedure · Other
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 2, 2026, 1:51 AM EDT
Not listed Not applicable Interventional

Computerized Cognitive Rehabilitation in MS Patients

NCT03729713
View directory record Official record
Conditions
Multiple Sclerosis, Cognitive Impairment
Interventions
Computerized cognitive rehabilitation, Sham placebo
Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 16, 2022 · Synced Sep 2, 2026, 1:51 AM EDT
Active, not recruiting Not applicable Interventional Results available

Parkinson's Disease: Enhancing Physical Therapy With Brain Stimulation for Treating Postural Instability.

NCT03981055
View directory record Official record
Conditions
Parkinson Disease
Interventions
Active Comparator: Active tDCS and Active TUS, Sham Comparator: Sham TDCS and Sham TUS, Physical Therapy
Device · Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
40 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Sep 2, 2026, 1:51 AM EDT
Completed Not applicable Interventional

Electrical Vestibular Nerve Stimulation (VeNS) Compared to Sham Control As a Means of Improving Glycemic Control in Adults with Type 2 Diabetes Mellitus

NCT04595968
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Vestal DM Active device, Lifestyle modification, Vestal DM Sham device
Device · Behavioral
Lead sponsor
Neurovalens Ltd.
Industry
Eligibility
22 Years to 70 Years
Enrollment
267 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
15
States / cities
Birmingham, Alabama • La Jolla, California • Sacramento, California + 12 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 2, 2026, 1:51 AM EDT
Completed Not applicable Interventional Results available

Improving ADHD Teen Driving

NCT02848092
View directory record Official record
Conditions
Attention Deficit Disorder, Attention Deficit Disorder With Hyperactivity
Interventions
FOCAL+, Rules of The road
Behavioral · Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
16 Years to 19 Years
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 2, 2023 · Synced Sep 2, 2026, 1:51 AM EDT
Terminated Not applicable Interventional

Effectiveness of Transcranial Direct Current Stimulation (tDCS).

NCT04902274
View directory record Official record
Conditions
Ankle Sprains, Musculoskeletal Injury
Interventions
Transcranial Direct Current Stimulation, Sham Transcranial Direct Current Stimulation, Physical Therapy
Other
Lead sponsor
Keller Army Community Hospital
Federal
Eligibility
18 Years to 40 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
West Point, New York
Source: ClinicalTrials.gov public record
Updated Apr 27, 2022 · Synced Sep 2, 2026, 1:51 AM EDT
Completed Not applicable Interventional Results available

Controlled Study of Kneehab XP for Patients Undergoing Total Knee Replacement

NCT01548040
View directory record Official record
Conditions
Total Knee Replacement
Interventions
Kneehab XP, Quadriceps TENS
Device
Lead sponsor
Theragen Inc.
Industry
Eligibility
40 Years and older
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 10, 2018 · Synced Sep 2, 2026, 1:51 AM EDT
Completed Not applicable Interventional

Nerve Stimulation Using a TENS to Provide Pain Relief During Surgery for Overactive Bladder

NCT05330117
View directory record Official record
Conditions
Urinary Incontinence, Overactive Bladder, Pain, Acute
Interventions
TENS, Control TENS
Procedure
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 14, 2022 · Synced Sep 2, 2026, 1:51 AM EDT
Recruiting Not applicable Interventional

Treatment of Post Traumatic Knee Osteoarthritis With Extracorporeal Shockwave Therapy

NCT06686680
View directory record Official record
Conditions
Knee Osteoarthristis, ACL Injuries, Post-Traumatic
Interventions
extracorporeal shockwave therapy (ESWT), Sham Comparator
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 55 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 3, 2025 · Synced Sep 2, 2026, 1:51 AM EDT
Completed Not applicable Interventional Results available

Development of a Multi-faceted Cognitive Training Program for Children With Attention Deficit Hyperactivity Disorder (ADHD)

NCT01352468
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder
Interventions
Multifaceted cognitive training
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
7 Years to 12 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 31, 2017 · Synced Sep 2, 2026, 1:51 AM EDT
Not yet recruiting Early Phase 1 Interventional Accepts healthy volunteers

Mild Cognitive Impairment Community Screening and Early Intervention Via Stem Cell Therapy and Wearable Brain Computer Interface Device.

NCT07214974
View directory record Official record
Conditions
Mild Cognitive Impairment (MCI), Early Stages of Cognitive Decline, Alzheimer's Disease Dementia, Alzheimer's Disease Diagnosis, Alzheimer's Disease and Related Dementias, Parkinson's Disease, Parkinson's Disease (PD), Parkinson's Disease With Wearing-off Motor Fluctuations, Dementia (Diagnosis), Dementia MCI (Mild Cognitive Impairment)
Interventions
Structured wellness care, Wearable brain-computer interface devices, Stem Cell Therapy - Experimental, Control - Placebo Comparator
Behavioral · Device · Biological + 1 more
Lead sponsor
Noah Tech, Corp.
Industry
Eligibility
55 Years and older
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Palisades Park, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Sep 2, 2026, 1:51 AM EDT
Not yet recruiting Not applicable Interventional

Extracorporeal Shockwave Therapy and Platelet-Rich Plasma for Midportion Achilles Tendinopathy

NCT07483320
View directory record Official record
Conditions
Achilles Injuries Tendon, Achilles Tendinopathy (AT), Achilles Tendinitis, Left Leg, Achilles Tendinitis, Right Leg, Achilles Tendon Pain, Achilles Tendonitis
Interventions
Platelet Rich Plasma, Extracorporeal Shockwave Therapy, Sham PRP, Sham ESWT
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 26, 2026 · Synced Sep 2, 2026, 1:51 AM EDT
Completed Not applicable Interventional

Cervical Spine Thrust Joint Manipulation for Temporomandibular Disorder

NCT03300297
View directory record Official record
Conditions
Temporomandibular Disorder
Interventions
Cervical Spine Thrust Joint Manipulation, Cervical Spine Sham Manipulation, Home Program, Suboccipital Release
Other
Lead sponsor
Bradley University
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
Peoria, Illinois • Washington, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 17, 2019 · Synced Sep 2, 2026, 1:51 AM EDT
Completed Not applicable Interventional Results available

EaseVRx for the Reduction of Chronic Pain and Opioid Use

NCT04139564
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
EaseVRx headset, Active control VR sham program
Device
Lead sponsor
AppliedVR Inc.
Industry
Eligibility
18 Years to 64 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 26, 2024 · Synced Sep 2, 2026, 1:51 AM EDT
Completed Not applicable Interventional Results available

The KNEEhabilitation Study: Improving Disability in Individuals With Knee Osteoarthritis

NCT02634814
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Transcutaneous Electrical Nerve Stimulation, Therapeutic Exercise, Sham Transcutaneous Electrical Nerve Stimulation
Device · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
40 Years to 75 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 5, 2019 · Synced Sep 2, 2026, 1:51 AM EDT
Not yet recruiting Not applicable Interventional

Reduction of Depression in People With Disabilities Through Dual Treatment: Digital CBT & NBHWC Coaching

NCT07195292
View directory record Official record
Conditions
Hearing Disability, Depression, Mobility Disability
Interventions
Sham Digital Program - General health education and interactive quizzes unrelated to depression or CBT., Toivoa-002 - A digital Cognitive Behavioral Therapy program combined with NBHWC-certified coaching.
Device
Lead sponsor
Toivoa Inc
Industry
Eligibility
22 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
4
States / cities
Dover, Delaware • East Orange, New Jersey • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Sep 2, 2026, 1:51 AM EDT
Completed Not applicable Interventional

Safety and Feasibility of Paired Vagus Nerve Stimulation With Rehabilitation for Improving Upper Extremity Function in People With Cervical Spinal Cord Injury

NCT05601661
View directory record Official record
Conditions
Cervical Spinal Cord Injury
Interventions
Active VNS, Sham VNS, Arm rehabilitation
Device · Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Sep 2, 2026, 1:51 AM EDT
Completed Phase 4 Interventional

Use of ThermaCare Heat Wraps and Ibuprofen as an Adjunct to Physical Therapy for Neck Pain

NCT02327338
View directory record Official record
Conditions
Heat, Pain
Interventions
thermacare heat wraps, Ibuprofen
Device · Drug
Lead sponsor
Future Sciene Technology
Industry
Eligibility
18 Years to 80 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Henderson, Nevada
Source: ClinicalTrials.gov public record
Updated Jul 31, 2017 · Synced Sep 2, 2026, 1:51 AM EDT
Recruiting Not applicable Interventional

EMST in Patients Undergoing CRT for HNCA

NCT03916809
View directory record Official record
Conditions
Head and Neck Neoplasms, Deglutition Disorders
Interventions
EMST
Other
Lead sponsor
University of Wisconsin, Milwaukee
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
2
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 3, 2024 · Synced Sep 2, 2026, 1:51 AM EDT
Terminated Not applicable Interventional

Augmenting Internet-Based Cognitive Behavioral Therapy for Major Depressive Disorder With Low-Level Light Therapy

NCT02898233
View directory record Official record
Conditions
Depression
Interventions
Deprexis, Active low-level light therapy, Sham low-level light therapy
Other · Device
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jul 24, 2024 · Synced Sep 2, 2026, 1:51 AM EDT
Completed Not applicable Interventional Results available

A Phase III Trial of e-TNS for the Acute Treatment of Migraine

NCT03465904
View directory record Official record
Conditions
Migraine
Interventions
Verum Cefaly® Abortive Program device, Sham Cefaly® Abortive Program device
Device
Lead sponsor
Cefaly Technology
Industry
Eligibility
18 Years to 65 Years
Enrollment
607 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
10
States / cities
Tempe, Arizona • Encino, California • New Haven, Connecticut + 7 more
Source: ClinicalTrials.gov public record
Updated Dec 10, 2024 · Synced Sep 2, 2026, 1:51 AM EDT
Completed Not applicable Interventional

Hamstring Tightness

NCT02516137
View directory record Official record
Conditions
Hamstring Tightness
Interventions
Dry needling, Sham needling, Blunt needle placement, Standard hamstring stretching exercise
Procedure · Other
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 4, 2017 · Synced Sep 2, 2026, 1:51 AM EDT
Active, not recruiting Phase 2 Interventional

Multimodal Therapy for the Treatment of Fatigue in Patients With Prostate Cancer Receiving Radiotherapy With Androgen Deprivation Therapy

NCT01410942
View directory record Official record
Conditions
Prostate Cancer
Interventions
Placebo, Methylphenidate, Counseling Sessions, Sham Exercise, Standardized Exercise Intervention Program, Cognitive Behavioral Therapy (CBT)
Other · Drug · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Male only
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 2, 2026, 1:51 AM EDT