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Showing 25–41 of 17 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Sham SCS Clear all
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Neuromodulation of the Cortex and Spinal Cord

NCT06586437
View directory record Official record
Conditions
Cerebral Palsy
Interventions
Clinical Assessments, Brain-Spinal Cord fMRI, Hoffmann Reflex Assessments, MEG Imaging, Transcutaneous Current Stimulation
Behavioral
Lead sponsor
Father Flanagan's Boys' Home
Other
Eligibility
11 Years to 45 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Boys Town, Nebraska
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Sep 8, 2026, 8:05 AM EDT
Recruiting Not applicable Interventional

Transcutaneous Electrical Stimulation for Stroke Patients

NCT06950593
View directory record Official record
Conditions
Upper Limb Hemiparesis Following Stroke
Interventions
Task Specific Training (TST), Transcutaneous electrical spinal cord stimulation (TESS), Sham transcutaneous electrical spinal cord stimulation (Sham TESS)
Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 11, 2025 · Synced Sep 8, 2026, 8:05 AM EDT
Recruiting Not applicable Interventional

Safety of Transcutaneous Electrical Stimulation Potentiating Recovery in Acute Spinal Cord Injury Syndromes

NCT07090473
View directory record Official record
Conditions
Acute Spinal Cord Injury (SCI), Acute Spinal Cord Injury of Traumatic Origin (tSCI)
Interventions
transcutaneous spinal cord stimulation, sham transcutaneous spinal cord stimulation
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 8, 2026, 8:05 AM EDT
Recruiting Not applicable Interventional

Spinal Cord Transcutaneous Stimulation Effect on Blood Pressure in Acute Spinal Cord Injury (SCI)

NCT05731986
View directory record Official record
Conditions
Spinal Cord Injuries, Spinal Cord Diseases, Trauma, Nervous System, Nervous System Diseases, Central Nervous System Diseases, Hypotension, Orthostatic Hypotension, Cardiovascular Diseases, Acute Spinal Cord Injury, Blood Pressure
Interventions
Orthostatic challenge, Biostim-5 transcutaneous spinal stimulation - Mapping, Biostim-5 transcutaneous spinal stimulation - "Optimal" testing, Biostim-5 transcutaneous spinal stimulation - "Sham" testing
Diagnostic Test · Device
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 75 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 1, 2025 · Synced Sep 8, 2026, 8:05 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Neural Facilitation of Movements in People With SCI

NCT05354206
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Electrophysiology assessment - corticospinal tract, Electrophysiology assessment - reticulospinal tract, Training with some stimulation
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
16 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Sep 8, 2026, 8:05 AM EDT
Recruiting Not applicable Interventional

Non-Invasive Interventions for Respiratory Recovery in Chronic Spinal Cord Injury

NCT07135583
View directory record Official record
Conditions
Spinal Cord Injury, Chronic, Spinal Cord Injury Cervical, Spinal Cord Injury Thoracic, Incomplete Spinal Cord Injury
Interventions
Active Comparator: Single Intervention 1, Active Comparator: Single Intervention 2, Respiratory Resistance Exercise
Other · Behavioral
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Sep 8, 2026, 8:05 AM EDT
Completed Not applicable Interventional Results available

Direct Comparison of Spinal Cord Stimulator Parameter Settings

NCT05283863
View directory record Official record
Conditions
Spinal Cord Stimulation, High-frequency Stimulation, High-density Stimulation
Interventions
High-frequency stimulation, Sham Stimulation
Device
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years to 75 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 20, 2024 · Synced Sep 8, 2026, 8:05 AM EDT
Recruiting Not applicable Interventional

Transcutaneous Spinal Cord Stimulation Combined With Arm Bike for Cardiovascular Recovery in SCI

NCT06313515
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Transcutaneous Spinal Cord Stimulation, Arm-crank bike exercise, Sham Stimulation
Device · Behavioral · Other
Lead sponsor
University of Washington
Other
Eligibility
21 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 8, 2026, 8:05 AM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Stimulation-based Therapy to Improve Balance in DCM

NCT07298460
View directory record Official record
Conditions
Degenerative Cervical Myelopathy
Interventions
Transcutaneous spinal cord stimulation, Balance and Gait Training
Device · Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
50 Years to 90 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Sep 8, 2026, 8:05 AM EDT
Recruiting Not applicable Interventional

Spinal Cord Stimulation for Autonomic Recovery in Inpatient Rehabilitation After Acute SCI

NCT06540859
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Transcutaneous Spinal Cord Stimulation, Sham Stimulation
Device
Lead sponsor
University of Washington
Other
Eligibility
21 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 26, 2025 · Synced Sep 8, 2026, 8:05 AM EDT
Completed Not applicable Interventional Results available

Sensory Testing of Multiple Forms of Spinal Cord Stimulation for Pain

NCT04732325
View directory record Official record
Conditions
Chronic Pain, Failed Back Surgery Syndrome, Complex Regional Pain Syndromes, Neuropathic Pain
Interventions
Spinal cord stimulation
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Sep 8, 2026, 8:05 AM EDT
Completed Not applicable Interventional

Transcutaneous Electrical Spinal Cord Stimulation for Lower Limbs

NCT01949285
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Transcutaneous Electrical Spinal Cord Stimulation
Device
Lead sponsor
NeuroEnabling Technologies, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 23, 2017 · Synced Sep 8, 2026, 8:05 AM EDT
Recruiting Not applicable Interventional

SCS for Patient With Painful Diabetic Neuropathy and Peripheral Arterial Disease

NCT06480786
View directory record Official record
Conditions
Peripheral Arterial Disease, Painful Diabetic Neuropathy, Diabetes Mellitus, Type 2, Chronic Pain, Spinal Cord Stimulation, Chronic Pain Syndrome, Limb Pain
Interventions
Spinal cord stimulation, Sham stimulation
Device
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 89 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced Sep 8, 2026, 8:05 AM EDT
Withdrawn Not applicable Interventional

The Biophysical Impact of Transcutaneous Spinal Cord Stimulation Within a Single Session

NCT03046875
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Transcutaneous Spinal Cord Stimulation, Sham stimulation
Other
Lead sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 27, 2018 · Synced Sep 8, 2026, 8:05 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Rehab and Mechanical Ventilation

NCT07427121
View directory record Official record
Conditions
Inspiratory Strength Training (IST), Transcutaneous Spinal Stimulation, Sham Spinal Stimulation
Interventions
Spinal cord stimulation, Inspiratory Strength Training, Sham Stimulation
Device · Behavioral · Other
Lead sponsor
University of Florida
Other
Eligibility
25 Years to 80 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 8, 2026, 8:05 AM EDT
Not yet recruiting Not applicable Interventional

Exoskeletal-assisted Walking Combined With Transcutaneous Spinal Cord Stimulation: Effect on Imaging and Serum Biomarkers of Skeletal Muscle Mass and Bone Strength.

NCT07418398
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Exoskeleton-Assisted Walking (EAW), Sham Transcutaneous Spinal Cord Stimulation (tSCS), Active Transcutaneous Spinal Cord Stimulation (tSCS)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 60 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
2
States / cities
West Orange, New Jersey • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Sep 8, 2026, 8:05 AM EDT
Recruiting Not applicable Interventional

Harnessing Neuroplasticity of Postural Sensorimotor Networks Using Non-Invasive Spinal Neuromodulation to Maximize Functional Recovery After Spinal Cord Injury

NCT06213012
View directory record Official record
Conditions
Spinal Cord Injuries, Neuromodulation
Interventions
Transcutaneous Spinal cord Stimulation, Epidural Spinal Stimulation (ESS)
Device
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
22 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 8, 2026, 8:05 AM EDT