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ClinicalTrials.gov public records Last synced Sep 17, 2026, 10:44 PM EDT

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Showing 1–24 of 165 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Sham Theta Burst Stimulation Clear all
Not yet recruiting Phase 2Phase 3 Interventional

A Randomized, Double-Blind Controlled Comparison of NRX-101 vs. Placebo for Adults Being Treated With Robotic Transcranial Magnetic Stimulation for Treatment Resistant Depression: The SPARC-TMS Trial

NCT07227103
View directory record Official record
Conditions
Treatment Resistant Depression, Treatment Resistant Depression (TRD)
Interventions
Neuronavigated robotic-enabled TMS, NRX-101, Sham TMS, Oral Placebo
Device · Drug
Lead sponsor
NeuroRx, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
3
States / cities
Sarasota, Florida • West Palm Beach, Florida • Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Sep 17, 2026, 10:44 PM EDT
Completed Not applicable Interventional Results available

Project Relief: Developing Brain Stimulation as a Treatment for Chronic Pain

NCT04156802
View directory record Official record
Conditions
Chronic Pain, Chronic Lower Back Pain, Back Pain, Opioid Use, Opiate Dependence, Pain, Chronic, Neuropathic Pain, Chemotherapy-induced Peripheral Neuropathy
Interventions
Real TBS to the mPFC, Sham TBS to the mPFC, Real TBS to the MC, Sham TBS to the MC
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 75 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 11, 2023 · Synced Sep 17, 2026, 10:44 PM EDT
Recruiting Phase 2 Interventional

Transcranial Magnetic Stimulation + Language Therapy to Treat Mild Aphasia

NCT06842745
View directory record Official record
Conditions
Aphasia, Stroke, Aphasia Following Cerebral Infarction, Aphasia, Acquired
Interventions
Transcranial Magnetic Stimulation (TMS), Speech-Language Therapy (SLT)
Device · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
40 Years to 85 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Sep 17, 2026, 10:44 PM EDT
Completed Not applicable Interventional Results available

Theta Burst Stimulation in Young Adults With Depression

NCT03737032
View directory record Official record
Conditions
Depression
Interventions
Intermittent Theta Burst Stimulation, Continuous Theta Burst Stimulation, Sham Theta Burst Stimulation
Device
Lead sponsor
Erika Forbes
Other
Eligibility
18 Years to 25 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 18, 2024 · Synced Sep 17, 2026, 10:44 PM EDT
Not listed Not applicable Interventional

Theta Burst TMS for Treatment of Methamphetamine Use Disorder

NCT06372288
View directory record Official record
Conditions
Methamphetamine Abuse
Interventions
Transcranial Magnetic Stimulation, Sham Transcranial Magnetic Stimulation
Device
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years to 55 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 25, 2024 · Synced Sep 17, 2026, 10:44 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Developing rTMS Treatment Strategies for Pain in Opiate Dependence

NCT03576781
View directory record Official record
Conditions
Pain, Chronic Pain, Opioid Dependence, Opioid Use
Interventions
Real iTBS, Sham iTBS, Real cTBS, Sham cTBS
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
2
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 5, 2020 · Synced Sep 17, 2026, 10:44 PM EDT
Recruiting Not applicable Interventional

Enhancing Prefrontal Oscillations and Working Memory in Early-course Schizophrenia

NCT05102929
View directory record Official record
Conditions
Schizophrenia
Interventions
active intermittent Theta Burst Stimulation (iTBS), sham intermittent Theta Burst Stimulation (iTBS)
Device
Lead sponsor
Fabio Ferrarelli
Other
Eligibility
18 Years to 40 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 17, 2026, 10:44 PM EDT
Not yet recruiting Phase 4 Interventional

Neuromodulation of Mood Switch Circuitry in Bipolar Disorder

NCT07680153
View directory record Official record
Conditions
Bipolar Disorder (BD), Bipolar 1 Depression, rTMS, fMRI
Interventions
MagVenture MagPro TMS system, Sham Stimulation
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 70 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 17, 2026, 10:44 PM EDT
Recruiting Not applicable Interventional

Individually Targeted Neuromodulation for Contamination-based OCD

NCT05048251
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
cTBS, iTBS, sham
Device
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 55 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 14, 2024 · Synced Sep 17, 2026, 10:44 PM EDT
Terminated Not applicable Interventional Results available

Intermittent Theta Burst for the Treatment of Alcohol Use Disorders in Veterans

NCT03291431
View directory record Official record
Conditions
Alcohol Use Disorder, Depressive Disorder, Cigarette Smoking
Interventions
Intermittent theta burst transcranial magnetic stimulation
Device
Lead sponsor
Stanford University
Other
Eligibility
21 Years to 65 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
2
States / cities
Palo Alto, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Oct 15, 2023 · Synced Sep 17, 2026, 10:44 PM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Measuring the Effects of Neurostimulation on Risky and Ambiguous Decision-Making Capacity in People With and Without Substance Use Disorder

NCT06577454
View directory record Official record
Conditions
Opioid Use Disorder, Healthy Volunteers
Interventions
TMS (MagVenture MagPro 100 with MagOption)
Device
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 60 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Sep 17, 2026, 10:44 PM EDT
Completed Not applicable Interventional Results available

Therapeutic Efficacy of Transcranial Magnetic Stimulation in Schizophrenia

NCT01551979
View directory record Official record
Conditions
Schizophrenia
Interventions
Repetitive Transcranial Magnetic Stimulation
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 11, 2018 · Synced Sep 17, 2026, 10:44 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effectiveness of Transcranial Magnetic Stimulation of the Default Mode Network to Improve Sleep - Clinical Trial

NCT06631209
View directory record Official record
Conditions
Insomnia
Interventions
Transcranial Magnetic Stimulation (TMS), Sham
Device · Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 60 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Sep 17, 2026, 10:44 PM EDT
Completed Phase 2 Interventional Results available

Individualized Functional Connectivity Targeting in aiTBS for Depression

NCT05680727
View directory record Official record
Conditions
Depressive Disorder, Major, Depression, Mood Disorders, Mental Disorder, Psychiatric Disorder
Interventions
transcranial magnetic stimulation
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
22 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Sep 17, 2026, 10:44 PM EDT
Recruiting Not applicable Interventional

Cortical Inhibition as a Biomarker of Response in a Comparison of Bilateral Versus Unilateral Accelerated Theta Burst Stimulation for Suicidal Ideation in Treatment-Resistant Depression -COMBAT-SI

NCT05377177
View directory record Official record
Conditions
Suicidal Ideation, Treatment-resistant Depression
Interventions
Accelerated Theta Burst Stimulation
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 70 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2030
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Sep 17, 2026, 10:44 PM EDT
Enrolling by invitation Not applicable Interventional

TMS in Anxiety-Parkinson's Disease

NCT06999330
View directory record Official record
Conditions
Parkinsons Disease (PD), Anxiety
Interventions
Theta burst stimulation active coil, Sham coil
Device
Lead sponsor
HealthPartners Institute
Other
Eligibility
40 Years to 90 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Sep 17, 2026, 10:44 PM EDT
Recruiting Not applicable Interventional

TMS for Complex Regional Pain Syndrome

NCT03137472
View directory record Official record
Conditions
Complex Regional Pain Syndromes
Interventions
Transcranial Magnetic Stimulation (TMS)
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2028
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Sep 17, 2026, 10:44 PM EDT
Not yet recruiting Not applicable Interventional

Early Brainwave Biomarkers for Personalized Neuromodulation in Treatment-resistant Depression

NCT07528157
View directory record Official record
Conditions
Major Depressive Disorder, Treatment Resistant Depression
Interventions
Personalized iTBS, Non-Personalized iTBS, Sham iTBS
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Sep 17, 2026, 10:44 PM EDT
Completed Not applicable Interventional

Theta Burst Stimulation to Improve Inhibitory Motor Physiology in Tourette Syndrome

NCT05628805
View directory record Official record
Conditions
Tourette Syndrome, Tourette Syndrome in Children, Tourette Syndrome in Adolescence, Tourette Syndrome, Modifier of
Interventions
iTBS
Device
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
10 Years to 21 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Sep 17, 2026, 10:44 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Novel Repetitive Synchronized Associative Stimulation Neuromodulation Approach for Spinal Cord Injury Patients

NCT06494059
View directory record Official record
Conditions
SCI - Spinal Cord Injury
Interventions
Intermittent theta burst stimulation (iTBS), Functional electrical stimulation (FES), Transcutaneous spinal cord stimulation (TSCS), Sham Intermittent theta burst stimulation (iTBS)
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Sep 17, 2026, 10:44 PM EDT
Recruiting Not applicable Interventional

Randomized Assessment of TcMS for VT Storm

NCT05599022
View directory record Official record
Conditions
Ventricular Tachycardia
Interventions
Magnetic Stimulation
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Sep 17, 2026, 10:44 PM EDT
Active, not recruiting Not applicable Interventional

Rapid Acting Transcranial Magnetic Stimulation

NCT04739969
View directory record Official record
Conditions
Treatment Resistant Depression
Interventions
Active TBS-DLPFC, Sham TBS-DLPFC
Device
Lead sponsor
Stanford University
Other
Eligibility
22 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 5, 2025 · Synced Sep 17, 2026, 10:44 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Functional Roles of Dorsolateral Prefrontal Cortex

NCT03882931
View directory record Official record
Conditions
Healthy Participants
Interventions
Theta Burst Transcranial Magnetic Stimulation, Focused Ultrasound, Sham
Other
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 35 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 18, 2019 · Synced Sep 17, 2026, 10:44 PM EDT
Recruiting Not applicable Interventional

ADHD PreSMA Response Inhibition Therapy

NCT06325813
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder
Interventions
Active repetitive TMS, Sham repetitive TMS
Device
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
12 Years to 17 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Sep 17, 2026, 10:44 PM EDT