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ClinicalTrials.gov public records Last synced Oct 11, 2026, 2:21 PM EDT

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Showing 169–192 of 524 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Sham Transcranial Direct Current Stimulation (Sham tDCS) Clear all
Completed Phase 2Phase 3 Interventional

Investigating tDCS as a Treatment for Unipolar and Bipolar Depression

NCT01562184
View directory record Official record
Conditions
Unipolar Depression, Bipolar Depression
Interventions
Sham tDCS device, Soterix tDCS device
Device
Lead sponsor
The University of New South Wales
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
5
States / cities
Atlanta, Georgia • Towson, Maryland • Cherry Hill, New Jersey + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 2, 2015 · Synced Oct 11, 2026, 2:21 PM EDT
Not yet recruiting Not applicable Interventional

Noninvasive Brain Stimulation Combined With Written Exposure Therapy for PTSD in Military Personnel With TBI

NCT07715799
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Transcranial Direct Current Stimulator, Written Exposure Therapy
Device · Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 70 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 11, 2026, 2:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Transcranial Direct Current Stimulation (tDCS) in Chronic Corneal Pain

NCT01575002
View directory record Official record
Conditions
Corneal Pain, Chronic Pain, Neuropathic Pain
Interventions
Transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Oct 11, 2026, 2:21 PM EDT
Completed Not applicable Interventional Results available

Transcranial Direct Current Stimulation (tDCS) As A Treatment For Cigarette Craving and Cognitive Deficits in Schizophrenic

NCT02128919
View directory record Official record
Conditions
Schizophrenia, Cognition, Cigarette Smoking
Interventions
tDCS
Device
Lead sponsor
Nathan Kline Institute for Psychiatric Research
Other
Eligibility
18 Years to 60 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Orangeburg, New York
Source: ClinicalTrials.gov public record
Updated Aug 30, 2017 · Synced Oct 11, 2026, 2:21 PM EDT
Completed Not applicable Interventional Results available

Self-Administered Transcranial Direct Current Stimulation for Pain in Older Adults With Knee Osteoarthritis

NCT04016272
View directory record Official record
Conditions
Osteo Arthritis Knee
Interventions
Active tDCS, Sham tDCS
Device
Lead sponsor
Florida State University
Other
Eligibility
50 Years to 85 Years
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 10, 2023 · Synced Oct 11, 2026, 2:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Non-invasive Brain Stimulation and Occupational Therapy To Enhance Stroke Recovery

NCT00792428
View directory record Official record
Conditions
Stroke, Cerebrovascular Accident, CVA, Acute Stroke, Acute Cerebrovascular Accident, Apoplexy
Interventions
Real Transcranial Direct Current Stimulation, Sham Transcranial Direct Current Stimulation
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
21 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 4, 2018 · Synced Oct 11, 2026, 2:21 PM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers Results available

Investigating Motor Cortex Processing for Pain Modulation

NCT01404039
View directory record Official record
Conditions
Motor Activity
Interventions
Motor Learning, Somatosensory Learning, Observational Task, Mental Imagery, transcranial direct current stimulation
Behavioral · Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 64 Years · Male only
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Oct 11, 2026, 2:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Transcranial Direct Current Stimulation on Human Brains: A Neuroimaging Study

NCT02421146
View directory record Official record
Conditions
Chronic Schizophrenia
Interventions
Transcranial direct current stimulation, Transcranial direct current stimulation - Sham
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 60 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Glen Oaks, New York
Source: ClinicalTrials.gov public record
Updated Apr 30, 2018 · Synced Oct 11, 2026, 2:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Transcranial Electrical Stimulation for Cervical Dystonia

NCT03369613
View directory record Official record
Conditions
Primary Cervical Dystonia
Interventions
transcranial electrical stimulation
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 25, 2022 · Synced Oct 11, 2026, 2:21 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Motor Learning in Dysphagia Rehabilitation

NCT02576470
View directory record Official record
Conditions
Dysphagia, Swallowing Disorders, Deglutition Disorders, Stroke
Interventions
Biofeedback, Transcranial Direct Current Stimulation, Financial Reward, targeted dysphagia training maneuver, Videofluoroscopy (VF) and Barium, Transcranial Magnetic Stimulation, Submental Electromyography
Behavioral · Device · Radiation
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 100 Years
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 4, 2019 · Synced Oct 11, 2026, 2:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of tDCS Applied During Sleep on Memory Consolidation

NCT02596568
View directory record Official record
Conditions
Sleep
Interventions
transcranial direct current stimulation (tDCS), Sham
Device · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 60 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 30, 2023 · Synced Oct 11, 2026, 2:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neurophysiological Effects on tPCS and tDCS on Healthy Subjects and on Patients With Chronic Visceral Pain

NCT02497196
View directory record Official record
Conditions
Visceral Pain, Pancreatitis, Pelvic Pain
Interventions
Active tPCS, Active tDCS, Sham tPCS, Sham tDCS
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Oct 11, 2026, 2:21 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Dorsolateral Prefrontal Cortex Transcranial Direct Current and Muscle Fatigue Stimulation on Muscle Fatigue

NCT06389162
View directory record Official record
Conditions
Fatigue
Interventions
transcranial direct current stimulation
Device
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Apr 29, 2024 · Synced Oct 11, 2026, 2:21 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Targeted Alternating Current and Cognitive Training Intervention for Cognitive Control in Bipolar Disorders

NCT07845409
View directory record Official record
Conditions
Bipolar Disorder, Bipolar and Related Disorders, Veterans, Suicide, Suicidal Ideation, Mental Disorders
Interventions
Soterix 1x1 tES mini-CT
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years and older
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2031
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 11, 2026, 2:21 PM EDT
Recruiting Phase 2 Interventional

Enhancing Modulation Effects of Baduanjin Through Neuromodulation for Knee OA

NCT05839535
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
BDJ, tDCS, sham tDCS, exercise
Behavioral · Device · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
45 Years to 75 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 11, 2026, 2:21 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Augmentation of Locomotor Adaptation Post-Stroke

NCT02892084
View directory record Official record
Conditions
Stroke
Interventions
tDCS, Sham tDCS
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 85 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 28, 2018 · Synced Oct 11, 2026, 2:21 PM EDT
Recruiting Not applicable Interventional

Non-invasive Brain Stimulation Using Tdcs of the Third (of Many) Visual Pathways

NCT07469384
View directory record Official record
Conditions
SCHIZOPHRENIA 1 (Disorder), Schizo Affective Disorder
Interventions
transcranial direct current stimulation, Sham stimulation
Device
Lead sponsor
Nathan Kline Institute for Psychiatric Research
Other
Eligibility
18 Years to 55 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Orangeburg, New York
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 11, 2026, 2:21 PM EDT
Completed Phase 1Phase 2 Interventional

Transcranial Direct Current Stimulation (tDCS) in Chronic Stroke Recovery

NCT01014897
View directory record Official record
Conditions
Stroke
Interventions
tDCS
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 13, 2020 · Synced Oct 11, 2026, 2:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Closed-loop System Using Transcranial Direct Current Stimulation (tDCS) for Epilepsy

NCT01415362
View directory record Official record
Conditions
Epilepsy, Seizures
Interventions
Transcranial Direct Current Stimulation
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Oct 11, 2026, 2:21 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Treating Depression With Transcranial Direct Current Stimulation (tDCS)

NCT00481988
View directory record Official record
Conditions
Depression
Interventions
transcranial direct current stimulation, iomed phoresor transcranial direct current stimulation
Device
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 20, 2013 · Synced Oct 11, 2026, 2:21 PM EDT
Completed Not applicable Interventional Results available

Improving Hallucinations by Targeting the rSTS With tES

NCT05165654
View directory record Official record
Conditions
Hallucinations, Auditory, Psychosis
Interventions
Transcranial Electrical Stimulation
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 50 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Oct 11, 2026, 2:21 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Patient-Centered NeuroRehabilitation (PCN)

NCT03036319
View directory record Official record
Conditions
Cognitive Deficit
Interventions
Active tDCS, Sham tDCS, Cognitively based intervention, Active tACS, Sham tACS, Active tRNS, Sham tRNS
Device · Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
50 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Oct 11, 2026, 2:21 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Overnight Thalamic TES-TI to Modulate Sleep Spindles in Individuals With Schizophrenia Spectrum Disorders and Matched Healthy Controls

NCT07680114
View directory record Official record
Conditions
Schizophrenia
Interventions
TES-TI, Sham TES-TI
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 11, 2026, 2:21 PM EDT
Not yet recruiting Not applicable Interventional

Neuromodulation for Patients With Parkinson's Disease

NCT07767006
View directory record Official record
Conditions
Adults With Parkinson's Disease
Interventions
tDCS combined with TUS
Device
Lead sponsor
Felipe Fregni, MD, PhD, MPH
Other
Eligibility
40 Years to 85 Years
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 11, 2026, 2:21 PM EDT