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ClinicalTrials.gov public records Last synced Oct 17, 2026, 4:29 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 34 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Sham VR Clear all
Completed Not applicable Interventional Accepts healthy volunteers

The Feasibility, Safety and Tolerability of VR-based Audiovisual Stimulation

NCT06234930
View directory record Official record
Conditions
Healthy Aging, Alzheimer's Disease
Interventions
Audiovisual stimulation VR system
Device
Lead sponsor
Clarity Health Technologies, Inc
Industry
Eligibility
50 Years to 90 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
2
States / cities
Portola Valley, California • Leesburg, Florida
Source: ClinicalTrials.gov public record
Updated Sep 2, 2025 · Synced Oct 17, 2026, 4:29 PM EDT
Completed Not applicable Interventional

Using Virtual Reality and Sensor Technology to Enhance Outcomes From Treatment for Binge Eating

NCT05041660
View directory record Official record
Conditions
Binge Eating, Inhibition (Psychology)
Interventions
Virtual-reality-based training, Inhibitory Control Training, Sham Inhibitory Control Training, Computerized training
Other
Lead sponsor
Drexel University
Other
Eligibility
18 Years to 65 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 13, 2021 · Synced Oct 17, 2026, 4:29 PM EDT
Completed Not applicable Interventional Results available

EaseVRx for the Reduction of Chronic Pain and Opioid Use

NCT04139564
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
EaseVRx headset, Active control VR sham program
Device
Lead sponsor
AppliedVR Inc.
Industry
Eligibility
18 Years to 64 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 27, 2024 · Synced Oct 17, 2026, 4:29 PM EDT
Completed Not applicable Interventional Results available

Virtual Reality Distraction for Reduction

NCT04416555
View directory record Official record
Conditions
Postoperative Pain
Interventions
Placebo comparator: VR googles and the non reality experience, Active Comparator: VR googles and the real VR program to enter act with and experience
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 27, 2023 · Synced Oct 17, 2026, 4:29 PM EDT
Withdrawn Not applicable Interventional

Personalized Approach Bias Modification in Heavy Drinking Veterans With Mild to Moderate Traumatic Brain Injury

NCT06380985
View directory record Official record
Conditions
Alcohol Use Disorder, Mild-Moderate Traumatic Brain Injury
Interventions
Personalized VR Alcohol Approach Bias Modification (ApBM) Condition, Sham Condition
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 27, 2024 · Synced Oct 17, 2026, 4:29 PM EDT
Recruiting Not applicable Interventional

Neural Mechanisms of Immersive Virtual Reality in Chronic Pain (VR TMD EEG)

NCT06214923
View directory record Official record
Conditions
Pain, Virtual Reality, Placebo, Temporomandibular Disorder
Interventions
RelieVRx, Sham-VR, No-VR (natural history control)
Device · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 88 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 17, 2026, 4:29 PM EDT
Active, not recruiting Not applicable Interventional

Virtual Reality in Hemodialysis to Improve Psychological Well-being

NCT05642364
View directory record Official record
Conditions
End Stage Kidney Disease, Depressive Symptoms
Interventions
Joviality(TM), Inert Virtual Reality
Behavioral · Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
21 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
3
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Oct 17, 2026, 4:29 PM EDT
Completed Not applicable Interventional

RCT of VR Therapy for IBS

NCT06687616
View directory record Official record
Conditions
IBS - Irritable Bowel Syndrome
Interventions
SynerGI, Sham VR
Device
Lead sponsor
Christopher Almario
Other
Eligibility
10 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
2
States / cities
Los Angeles, California • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced Oct 17, 2026, 4:29 PM EDT
Completed Not applicable Interventional

A Nature-Based Virtual Reality (VR) Intervention in Family Caregivers of Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Recipients

NCT05909202
View directory record Official record
Conditions
Neoplasm, Caregivers
Interventions
Sham VR, Active VR
Device
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years to 100 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Oct 17, 2026, 4:29 PM EDT
Completed Not applicable Interventional Results available

Use of J3 Bioscience Lubricating Intravaginal Ring VR101 to Relieve the Symptoms of Vaginal Dryness

NCT03150407
View directory record Official record
Conditions
Menopause Related Conditions, Postmenopausal Symptoms
Interventions
VR101 Device (Efficacy), Sham Control Ring, VR101 Device (Safety)
Device · Other
Lead sponsor
J3 Bioscience, Inc.
Industry
Eligibility
35 Years and older · Female only
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
2
States / cities
Meridian, Idaho • West Jordan, Utah
Source: ClinicalTrials.gov public record
Updated Nov 7, 2022 · Synced Oct 17, 2026, 4:29 PM EDT
Completed Not applicable Interventional

Enhancing Prospective Thinking in Early Recovery (PARK)

NCT05908097
View directory record Official record
Conditions
Opioid Use, Opioid Use Disorder, Substance Use Disorders
Interventions
Virtual Reality Avatar Intervention, Virtual Reality Empty Park
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 60 Years
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Indianapolis, Indiana • Coburg, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 17, 2026, 4:29 PM EDT
Completed Not applicable Interventional Results available

tDCS Plus Virtual Reality for PTSD

NCT03372460
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Active stimulation, Sham stimulation, Virtual Reality (VR)
Device · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 13, 2024 · Synced Oct 17, 2026, 4:29 PM EDT
Active, not recruiting Phase 1Phase 2 Interventional

Neural Mechanisms of Immersive Virtual Reality in Chronic Pain

NCT04851301
View directory record Official record
Conditions
Pain, Virtual Reality, Placebo, Temporomandibular Disorder
Interventions
Active Virtual Reality, sham Virtual Reality, No Intervention, Naloxone, Saline, Natural history
Behavioral · Other · Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 88 Years
Enrollment
259 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 17, 2026, 4:29 PM EDT
Not yet recruiting Not applicable Interventional

VR Pilot for Pancreatitis

NCT06362187
View directory record Official record
Conditions
Chronic Pancreatitis, Recurrent Pancreatitis
Interventions
Gut Directed VR, Sham Control VR
Device
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 17, 2026, 4:29 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Functional Near-Infrared Spectroscopy and Virtual Reality Relaxation Programs for Pain Management in Patients With Cancer

NCT06456411
View directory record Official record
Conditions
Breast Carcinoma, Kidney Carcinoma, Carcinoma
Interventions
Functional Near-Infrared Spectroscopy, Questionnaire Administration, Virtual Technology Intervention, Cold Stimulation
Procedure · Other
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 17, 2026, 4:29 PM EDT
Recruiting Not applicable Interventional

Virtual Reality Mindfulness Meditation After ACL Reconstruction

NCT05527171
View directory record Official record
Conditions
Anterior Cruciate Ligament Injury
Interventions
Virtual Reality Mindfulness Meditation, Virtual Reality Sham
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
14 Years to 25 Years · Female only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 17, 2026, 4:29 PM EDT
Recruiting Not applicable Interventional

DevRobust Treatment for Mal de Débarquement Syndrome

NCT05460520
View directory record Official record
Conditions
Mal de Débarquement Syndrome
Interventions
VOR Readaptation, VOR Habituation, Visual Motion Desensitization, Opposing visual motion stimulus
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 78 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 17, 2026, 4:29 PM EDT
Recruiting Not applicable Interventional

Improving Visual Field Deficits With Noninvasive Brain Stimulation

NCT05085210
View directory record Official record
Conditions
Visual Field Defect, Peripheral, Stroke, Visual Impairment, Hemianopsia, Quadrantanopia, Cortical Blindness, Visual Field Defect Homonymous Bilateral, Occipital Lobe Infarct, Visual Fields Hemianopsia
Interventions
transcranial random noise stimulation (tRNS), Computer Based Visual Training, Sham stimulation, Virtual Reality Based Visual Training
Device · Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Oct 17, 2026, 4:29 PM EDT
Not yet recruiting Not applicable Interventional

Visual Restoration Using Focused Ultrasound Stimulation and Immersive Virtual Reality After Stroke

NCT06875206
View directory record Official record
Conditions
Stroke, Visual Field Defect, Visual Field Defect Following Cerebrovascular Accident, Hemianopia, Quadrantanopia, Occipital Lobe Infarct, Visual Fields Hemianopsia
Interventions
Low-intensity focused ultrasound, Immersive virtual reality, Inactive Low-intensity focused ultrasound
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 17, 2026, 4:29 PM EDT
Active, not recruiting Not applicable Interventional Results available

EaseVRx-8w+ for the Treatment of Chronic Lower Back Pain

NCT05263037
View directory record Official record
Conditions
Chronic Low-back Pain, Anxiety, Depression
Interventions
EaseVRx, Sham VR
Device
Lead sponsor
AppliedVR Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
1,093 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Van Nuys, California
Source: ClinicalTrials.gov public record
Updated Jan 29, 2025 · Synced Oct 17, 2026, 4:29 PM EDT
Recruiting Not applicable Interventional

Virtual Reality for SCD VOC

NCT07674277
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
Sham 2D Headset Control, Passive Immersive 3D Virtual Reality, Active Immersive Interactive 3D Virtual Reality
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 88 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 17, 2026, 4:29 PM EDT
Completed Not applicable Interventional

Intraoperative VR for Older Patients Undergoing TKA

NCT04748549
View directory record Official record
Conditions
Total Knee Arthroplasty
Interventions
Virtual Reality Immersive Relaxation, Immersive Audio Experience, Sham Virtual Reality Experience
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
60 Years and older
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Oct 17, 2026, 4:29 PM EDT
Recruiting Not applicable Interventional

Functional Dyspepsia Treatment Using Virtual Reality

NCT05836597
View directory record Official record
Conditions
Functional Dyspepsia
Interventions
Virtual reality
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Oct 17, 2026, 4:29 PM EDT
Active, not recruiting Not applicable Interventional

A Study Of Virtual Reality Vs Sham VR On Fibromyalgia

NCT07202572
View directory record Official record
Conditions
Fibromyalgia
Interventions
TRIPP VR Meditation, Sham VR
Device · Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 17, 2026, 4:29 PM EDT