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Showing 1–24 of 53 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Sham continuous theta burst stimulation Clear all
Recruiting Not applicable Interventional

Mechanisms Of Orbitofrontal Stimulation in Depression

NCT07230990
View directory record Official record
Conditions
Major Depressive Disorder (MDD)
Interventions
Sham TMS, Active TMS
Device
Lead sponsor
Subha Subramanian
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Sep 20, 2026, 9:32 PM EDT
Recruiting Not applicable Interventional

Individually Targeted Neuromodulation for Contamination-based OCD

NCT05048251
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
cTBS, iTBS, sham
Device
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 55 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 14, 2024 · Synced Sep 20, 2026, 9:32 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neural Basis of Sensory Learning: Brain Regions

NCT05079516
View directory record Official record
Conditions
Basic Science
Interventions
Theta burst transcranial magnetic stimulation
Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 45 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Sep 20, 2026, 9:32 PM EDT
Completed Not applicable Interventional

Sequential Bilateral Accelerated Theta Burst Stimulation in Adolescents With Suicidal Ideation

NCT04502758
View directory record Official record
Conditions
Suicidal Ideation, Major Depressive Disorder
Interventions
MagVenture TMS Therapy System w/Theta Burst Stimulation, Sham MagVenture TMS Therapy System w/Theta Burst Stimulation
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
12 Years to 18 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 20, 2026, 9:32 PM EDT
Recruiting Early Phase 1 Interventional

Developing Transcranial Neuromodulation Protocols for Learning and Decision-Making

NCT06561828
View directory record Official record
Conditions
Normal Physiology
Interventions
continuous Theta Burst Stimulation (cTBS), intermittent Theta Burst Stimulation (iTBS), sham Theta Burst Stimulation (sham TBS)
Device
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 45 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2044
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Sep 20, 2026, 9:32 PM EDT
Enrolling by invitation Not applicable Interventional

Causal Role of Rostromedial Prefrontal Cortex for Positive Savoring in Depression

NCT07467473
View directory record Official record
Conditions
Left Rostromedial Prefrontal Cortex - Accelerated Intermittent Theta Burst, Left Dorsolateral Prefrontal Cortex - Accelerated Intermittent Theta Burst, Left Primary Somatosensory Cortex - Accelerated Intermittent Theta Burst
Interventions
Accelerated Intermittent Theta Burst Transcranial Magnetic Stimulation
Device
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Sep 20, 2026, 9:32 PM EDT
Recruiting Not applicable Interventional

TMS + Exposure Therapy for Pediatric OCD

NCT05931913
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Transcranial Magnetic Stimulation: intermittent theta burst to dorsolateral prefrontal cortex, Exposure with Response Prevention, Transcranial Magnetic Stimulation: Sham, Transcranial Magnetic Stimulation: continuous theta burst to pre supplementary motor area
Device · Behavioral
Lead sponsor
Bradley Hospital
Other
Eligibility
12 Years to 21 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
2
States / cities
Minneapolis, Minnesota • Riverside, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 20, 2026, 9:32 PM EDT
Completed Not applicable Interventional

Theta Burst Stimulation Plus Habit Override Training for Compulsive Behaviors

NCT04580043
View directory record Official record
Conditions
Compulsive Behavior, Obsessive-Compulsive Disorder
Interventions
Habit Override Practice, Transcranial Magnetic Stimulation, Sham Training, Sham Transcranial Magnetic Stimulation
Behavioral · Device
Lead sponsor
Rebecca Price
Other
Eligibility
18 Years to 60 Years
Enrollment
203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Sep 20, 2026, 9:32 PM EDT
Recruiting Not applicable Interventional

Cerebellar Modulation of Cognition in Psychosis

NCT06107764
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder, Bipolar Disorder I, Psychosis
Interventions
intermittant theta burst stimulation (iTBS), continuous theta burst stimulation (cTBS), sham rTMS
Device
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 55 Years
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
2
States / cities
Belmont, Massachusetts • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Sep 20, 2026, 9:32 PM EDT
Terminated Not applicable Interventional Results available

Repetitive TMS and Occupational Therapy in Children and Young Adults With Chronic Hemiparesis

NCT02057276
View directory record Official record
Conditions
Pediatric Stroke, Cerebral Palsy, Chronic Hemiparesis
Interventions
Repetitive Transcranial Magnetic Stimulation, Sham Repetitive Transcranial Magnetic Stimulation, Occupational Therapy
Device · Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
10 Years to 20 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 13, 2017 · Synced Sep 20, 2026, 9:32 PM EDT
Recruiting Not applicable Interventional

Transcranial Magnetic Stimulation of the Default Mode Network to Improve Sleep

NCT04953559
View directory record Official record
Conditions
Insomnia, Primary
Interventions
Active cTBS, Sham cTBS
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 16, 2022 · Synced Sep 20, 2026, 9:32 PM EDT
Completed Phase 4 Interventional

Rapid Antidepressant Improvement Secondary to Excitatory Brain Responses

NCT04276259
View directory record Official record
Conditions
Major Depressive Disorder, Depression
Interventions
Buprenorphine, Naltrexone, Oral Placebo, IM Placebo, Theta burst stimulation (TBS) of the ventromedial prefrontal cortex.
Drug · Device
Lead sponsor
Marta Peciña, MD PhD
Other
Eligibility
18 Years to 55 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Sep 20, 2026, 9:32 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Testing a Neurocognitive Model of Distancing Using Transcranial Magnetic Stimulation.

NCT03698591
View directory record Official record
Conditions
Emotion Regulation, Real Versus Sham Transcranial Magnetic Stimulation (TMS)
Interventions
Transcranial magnetic stimulation task, Sham transcranial magnetic stimulation task
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 39 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Sep 20, 2026, 9:32 PM EDT
Completed Not applicable Interventional Results available

TMS for Improving Response Inhibition in Adolescents With OCD

NCT05104697
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
Bradley Hospital
Other
Eligibility
13 Years to 18 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Riverside, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 27, 2025 · Synced Sep 20, 2026, 9:32 PM EDT
Recruiting Not applicable Interventional

Rapid Antidepressant Dynamics in Acute Neuromodulation Treatments

NCT06976840
View directory record Official record
Conditions
Depression, Major Depressive Disorder
Interventions
Intermittent theta burst stimulation, Sham theta burst stimulation, Continuous theta burst stimulation
Device
Lead sponsor
Marta Peciña, MD PhD
Other
Eligibility
18 Years to 55 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 20, 2026, 9:32 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neuromodulation of Brain and Emotional Responses to Psychological Stress

NCT06603064
View directory record Official record
Conditions
Healthy, Anxiety
Interventions
Active continuous theta burst stimulation, Sham continuous theta burst stimulation
Device
Lead sponsor
University of Pittsburgh
Other
Eligibility
30 Years to 50 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 20, 2026, 9:32 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Frontal and Parietal Contributions to Proprioception and Motor Skill Learning

NCT05739994
View directory record Official record
Conditions
Basic Science
Interventions
Theta burst transcranial magnetic stimulation, Sham theta burst transcranial magnetic stimulation
Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 45 Years
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Sep 20, 2026, 9:32 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Theta Burst Stimulation on the Brain, Behavior, and Clinical Symptoms in Adults With Bipolar Disorder

NCT04696471
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Continuous Theta Burst Stimulation (cTBS), Sham Continuous Theta Burst Stimulation (Sham cTBS)
Device
Lead sponsor
Mary Phillips, MD MD (Cantab)
Other
Eligibility
18 Years to 35 Years
Enrollment
146 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Sep 20, 2026, 9:32 PM EDT
Completed Early Phase 1 Interventional

The Effects of Theta Burst Stimulation on the Brain Response to Drug and Alcohol Cues

NCT02939352
View directory record Official record
Conditions
Alcoholism, Cocaine Addiction, Drug Addiction
Interventions
Real continuous Theta Burst Stimulation, Sham continuous Theta Burst Stimulation
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
25 Years to 55 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 22, 2018 · Synced Sep 20, 2026, 9:32 PM EDT
Completed Not applicable Interventional Results available

Theta Burst Stimulation in Young Adults With Depression

NCT03737032
View directory record Official record
Conditions
Depression
Interventions
Intermittent Theta Burst Stimulation, Continuous Theta Burst Stimulation, Sham Theta Burst Stimulation
Device
Lead sponsor
Erika Forbes
Other
Eligibility
18 Years to 25 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 18, 2024 · Synced Sep 20, 2026, 9:32 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effectiveness of Transcranial Magnetic Stimulation of the Default Mode Network to Improve Sleep - Clinical Trial

NCT06631209
View directory record Official record
Conditions
Insomnia
Interventions
Transcranial Magnetic Stimulation (TMS), Sham
Device · Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 60 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Sep 20, 2026, 9:32 PM EDT
Recruiting Not applicable Interventional

Disrupting Fear-based Memory Consolidation

NCT05560113
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Continuous theta burst stimulation (cTBS), Sham continuous theta burst stimulation (cTBS)
Other
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 28, 2025 · Synced Sep 20, 2026, 9:32 PM EDT
Terminated Not applicable Interventional Results available

QuitFast: Evaluating Transcranial Magnetic Stimulation as a Tool to Reduce Smoking Directly Following a Quit Attempt

NCT03576768
View directory record Official record
Conditions
Smoking, Cigarette, Craving, Addiction, Nicotine
Interventions
Real cTBS, Sham cTBS, Real iTBS, Sham iTBS
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 23, 2021 · Synced Sep 20, 2026, 9:32 PM EDT
Recruiting Early Phase 1 Interventional

Synaptic Mechanisms of Continuous Theta Burst Stimulation in Depression

NCT07560878
View directory record Official record
Conditions
Major Depression
Interventions
D-Cycloserine (DCS), Continuous theta-burst stimulation (cTBS), Transcranial Magnetic Stimulation Sham, Memantine, Lorazepam (drug), Baclofen, Placebo
Drug · Device
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Sep 20, 2026, 9:32 PM EDT