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ClinicalTrials.gov public records Last synced Oct 27, 2026, 10:56 PM EDT

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Showing 1–24 of 48 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Sham diet Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Acute Grape Seed Extract Supplementation on the Heart Rate Recovery in Young Individuals

NCT07137988
View directory record Official record
Conditions
Healthy Young Men
Interventions
600 mg grape seed extract, 600 mg Starch
Dietary Supplement
Lead sponsor
California Baptist University
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Riverside, California
Source: ClinicalTrials.gov public record
Updated Aug 22, 2025 · Synced Oct 27, 2026, 10:56 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Treatment of Mild Gestational Diabetes With Glyburide Versus Placebo

NCT00744965
View directory record Official record
Conditions
Mild Gestational Diabetes
Interventions
Glyburide, Placebo
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
16 Years to 45 Years · Female only
Enrollment
395 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2016
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 12, 2020 · Synced Oct 27, 2026, 10:56 PM EDT
Completed Phase 1Phase 2 Interventional

Result of tDCS in ASD Children With Comorbidities Like PANDAS, Rare Genetic Diseases or Autoimmune Disorders

NCT06368726
View directory record Official record
Conditions
Attention, Visual Perceptual Weakness, Social Behavior, Fluency Disorder, EEG With Periodic Abnormalities
Interventions
tDCS or Transcranial Direct Current Stimulation, Risperidone, Sham tDCS
Device · Drug · Other
Lead sponsor
Spanish Foundation for Neurometrics Development
Other
Eligibility
6 Years to 11 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 27, 2026, 10:56 PM EDT
Recruiting Phase 2 Interventional

Neuroimaging Correlates and Feasibility of Transcranial Magnetic Stimulation (TMS) to Improve Smoking Cessation Outcomes in Veterans With Comorbid PTSD

NCT05723588
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
active repetitive transcranial magnetic stimulation, sham repetitive transcranial magnetic stimulation, cognitive behavioral therapy for smoking cessation, nicotine replacement therapy
Device · Behavioral · Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Oct 27, 2026, 10:56 PM EDT
Completed Not applicable Interventional

The Health Effects of a Blueberry Enriched Diet on Obese Children

NCT01809795
View directory record Official record
Conditions
Obesity
Interventions
Blueberry Smoothie, Sham Smoothie
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
12 Years to 17 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 18, 2014 · Synced Oct 27, 2026, 10:56 PM EDT
Completed Not applicable Interventional

Training Response Inhibition to Obesogenic Foods

NCT04659837
View directory record Official record
Conditions
Inhibitory Control Training, Gameifaction
Interventions
No-Added-Sugar Diet
Behavioral
Lead sponsor
Drexel University
Other
Eligibility
18 Years to 65 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 9, 2020 · Synced Oct 27, 2026, 10:56 PM EDT
Recruiting Not applicable Interventional

THREAT: Testing Harms Related to Exposure to Allergenic and Epithelial Toxins

NCT07271381
View directory record Official record
Conditions
Allergic, Inflammatory
Interventions
Environmental Exposures, Control Exposures
Other
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 27, 2026, 10:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Fiber and Fish Oil Supplements for the Prevention of Colorectal Cancer

NCT04211766
View directory record Official record
Conditions
Healthy Subject
Interventions
Dietary Fiber, Fish Oil, Comparator
Dietary Supplement · Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
50 Years to 75 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 27, 2024 · Synced Oct 27, 2026, 10:56 PM EDT
Completed Not applicable Interventional

Gluten Immunity and Islet Autoimmunity in Type-1 Diabetes

NCT01932476
View directory record Official record
Conditions
Type 1 Diabetes, Celiac Disease
Interventions
Gluten Challenge, Sham Challenge
Dietary Supplement
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 50 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Oct 27, 2026, 10:56 PM EDT
Completed Not applicable Interventional

Auricular Point Acupressure to Self-Manage Chronic Pain or Aromatase Inhibitor Musculoskeletal Symptoms in Breast Cancer Survivors: Effectiveness and Scientific Underpinnings

NCT03697200
View directory record Official record
Conditions
Aromatase Inhibitor, Musculoskeletal Symptoms, Postmenopausal Breast Cancer Survivors
Interventions
APA, Sham APA control, Education control
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Female only
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 28, 2021 · Synced Oct 27, 2026, 10:56 PM EDT
Completed Not applicable Interventional Results available

ENDObesity® II Study: TransPyloric Shuttle® System for Weight Loss

NCT02518685
View directory record Official record
Conditions
Obesity
Interventions
TransPyloric Shuttle, Sham procedure, Lifestyle Counseling
Device · Behavioral
Lead sponsor
BaroNova, Inc.
Industry
Eligibility
22 Years to 60 Years
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
9
States / cities
Scottsdale, Arizona • San Diego, California • Miami, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 17, 2019 · Synced Oct 27, 2026, 10:56 PM EDT
Recruiting Not applicable Interventional

Low FODMAP Plus PEG 3350 for the Treatment of Patients with Irritable Bowel Syndrome-Constipation

NCT03687814
View directory record Official record
Conditions
Irritable Bowel Syndrome Characterized by Constipation
Interventions
Low FODMAP diet/PEG 3350, sham diet/PEG 3350
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 4, 2025 · Synced Oct 27, 2026, 10:56 PM EDT
Completed Not applicable Interventional Results available

Obalon Balloon System Pivotal IDE (SMART) Trial

NCT02235870
View directory record Official record
Conditions
Obesity
Interventions
Obalon Intragastric Balloons, Sham Device, Nutrition and Lifestyle Program
Device · Behavioral
Lead sponsor
Obalon Therapeutics, Inc.
Industry
Eligibility
22 Years to 64 Years
Enrollment
711 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
15
States / cities
Scottsdale, Arizona • Anaheim, California • Coronado, California + 12 more
Source: ClinicalTrials.gov public record
Updated Mar 8, 2018 · Synced Oct 27, 2026, 10:56 PM EDT
Recruiting Not applicable Interventional

The Path Study: Cognitive and Inflammation Targeted Gut-brain Interventions in Alcohol; Probiotics, Alcohol, Transcutaneous Vagus Nerve Stimulation, and HIV Study

NCT05090267
View directory record Official record
Conditions
Cognition, Gut Microbiome
Interventions
Probiotic Supplement, Transcutaneous Vagal Nerve Stimulation (tVNS)
Dietary Supplement · Device
Lead sponsor
University of Florida
Other
Eligibility
35 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 27, 2026, 10:56 PM EDT
Completed Not applicable Interventional Results available

A Prospective, Randomized Multicenter Study to Evaluate the Safety and Efficacy of the ReShape Duo™ Intragastric Balloon System in Obese Subjects

NCT01673698
View directory record Official record
Conditions
Obesity
Interventions
ReShape Duo balloon, Diet counseling, Exercise counseling
Device · Other
Lead sponsor
ReShape Lifesciences
Industry
Eligibility
21 Years to 60 Years
Enrollment
326 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
8
States / cities
Scottsdale, Arizona • Dalton, Georgia • Marquette, Michigan + 5 more
Source: ClinicalTrials.gov public record
Updated Dec 7, 2015 · Synced Oct 27, 2026, 10:56 PM EDT
Completed Phase 1 Interventional

Treatment of Orthostatic Hypotension in Autonomic Failure

NCT00223691
View directory record Official record
Conditions
Autonomic Failure, Orthostatic Hypotension
Interventions
Atomoxetine, Acarbose, Pyridostigmine Bromide, Yohimbine, Midodrine HCl, placebo, Modafinil, Octreotide, water intake, Diphenhydramine Hydrochloride, Ranitidine HCL, Tranylcypromine, Ergotamine/ Caffeine, Celecoxib, Pseudoephedrine, Methylphenidate, Indomethacin, Ibuprofen, Oxymetazoline 0.05% nasal solution, Bovril, Acetazolamide, Rivastigmine tartrate, Carbidopa/levodopa, Inflatable abdominal binder, inflatable abdominal binder (sham)
Drug · Other · Dietary Supplement + 1 more
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 85 Years
Enrollment
389 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2017
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 18, 2017 · Synced Oct 27, 2026, 10:56 PM EDT
Recruiting Not applicable Interventional

IBS Skin Patch Test Food Allergy Study

NCT06288672
View directory record Official record
Conditions
Irritable Bowel Syndrome
Interventions
True avoidance diet, Sham avoidance diet
Other
Lead sponsor
IBS-80, LLC
Industry
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
North Wales, Pennsylvania • Barboursville, West Virginia
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Oct 27, 2026, 10:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Healthy Behaviors Learning Task and Sleep

NCT02910648
View directory record Official record
Conditions
Overweight/Obese Population
Interventions
Modified Go/No-Go Task
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
20 Years to 55 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 8, 2022 · Synced Oct 27, 2026, 10:56 PM EDT
Terminated Phase 2Phase 3 Interventional Results available

Adrabetadex to Treat Niemann-Pick Type C1 (NPC1) Disease

NCT04958642
View directory record Official record
Conditions
Niemann-Pick Disease, Type C
Interventions
Adrabetadex
Drug
Lead sponsor
Mandos LLC
Industry
Eligibility
4 Years to 21 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
15
States / cities
Birmingham, Alabama • Orange, California • San Francisco, California + 12 more
Source: ClinicalTrials.gov public record
Updated Aug 29, 2023 · Synced Oct 27, 2026, 10:56 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Nutritional Supplement, Eccentric Exercise and Recovery

NCT01444170
View directory record Official record
Conditions
Injury, Inflammation
Interventions
dicreatinol sulfate, placebo sugar pill
Dietary Supplement · Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 25 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 15, 2019 · Synced Oct 27, 2026, 10:56 PM EDT
Completed Not applicable Interventional Results available

Resin Infiltration to Arrest Early Tooth Decay

NCT01584024
View directory record Official record
Conditions
Dental Caries
Interventions
Resin infiltration, Sham treatment
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 24 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
West Point, New York
Source: ClinicalTrials.gov public record
Updated Feb 12, 2019 · Synced Oct 27, 2026, 10:56 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Spices for Cultivating a Healthy Gut Microbiome and Cardiometabolic Profile

NCT06313580
View directory record Official record
Conditions
Cardiometabolic Syndrome
Interventions
Yogurt with added Spices, Yogurt without added Spices
Other
Lead sponsor
University of Alabama, Tuscaloosa
Other
Eligibility
50 Years to 69 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Tuscaloosa, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 20, 2024 · Synced Oct 27, 2026, 10:56 PM EDT
Completed Not applicable Interventional Results available

The Immune Directed Individualized Elimination Therapy (iDIET) Study

NCT05543512
View directory record Official record
Conditions
Eosinophilic Esophagitis, EoE
Interventions
Algorithm to diagnose food allergens, Sham diet
Device · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
16 Years to 80 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 27, 2026, 10:56 PM EDT
Not listed Phase 1Phase 2 Interventional

LIWA for Treatment of Alzheimer Patients

NCT02204969
View directory record Official record
Conditions
Alzheimer Disease
Interventions
Lithia water, Transcranial Magnetic stimulation
Dietary Supplement · Device
Lead sponsor
American Society Of Thermalism And Climatology Inc
Other
Eligibility
50 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 6, 2015 · Synced Oct 27, 2026, 10:56 PM EDT