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ClinicalTrials.gov public records Last synced Sep 6, 2026, 2:20 AM EDT

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Showing 1–24 of 32 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Sham filter Clear all
Not yet recruiting Not applicable Interventional

Circadian Light Exposure Adjustment for Restfulness

NCT07391852
View directory record Official record
Conditions
Sleep Onset Latency
Interventions
Amber Tinted Glasses, Clear Glasses, Smart Lightbulbs
Device
Lead sponsor
University of Arizona
Other
Eligibility
60 Months to 83 Months
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Sep 6, 2026, 2:20 AM EDT
Recruiting Not applicable Interventional

Using Indoor Air Filtration to Slow Atherothrombosis Progression in Adults With Ischemic Heart Disease History

NCT05867381
View directory record Official record
Conditions
Air Pollution, Atherosclerosis
Interventions
HEPA filtration, Sham filtration
Device
Lead sponsor
University of Southern California
Other
Eligibility
65 Years to 84 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Sep 6, 2026, 2:20 AM EDT
Recruiting Phase 3 Interventional

Multi-Center Clean Air Randomized Controlled Trial in COPD

NCT06376994
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
Air cleaner, Sham air cleaner
Device
Lead sponsor
JHSPH Center for Clinical Trials
Other
Eligibility
40 Years and older
Enrollment
770 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
11
States / cities
Birmingham, Alabama • Los Angeles, California • Iowa City, Iowa + 7 more
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Sep 6, 2026, 2:20 AM EDT
Not yet recruiting Phase 3 Interventional

RB-PDT for Fusarium Keratitis: The LUMIERE Study

NCT07743489
View directory record Official record
Conditions
Fusarium Keratitis
Interventions
Rose Bengal Photodynamic Therapy, Sham RB-PDT
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
434 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
2
States / cities
Palo Alto, California • Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 16, 2026 · Synced Sep 6, 2026, 2:20 AM EDT
Completed Not applicable Interventional Results available

Motivational Interviewing and Air Cleaners for Smokers With COPD (MOVE COPD)

NCT03658538
View directory record Official record
Conditions
COPD, Chronic Obstructive Pulmonary Disease
Interventions
Active HEPA Air Cleaner, Motivational interviewing, Sham Air Cleaner
Device · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
40 Years and older
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 23, 2025 · Synced Sep 6, 2026, 2:20 AM EDT
Completed Not applicable Interventional

Cleaner Air for Lower Cardiometabolic Risk

NCT05994937
View directory record Official record
Conditions
PreDiabetes
Interventions
PAC with HEPA filter intact, PAC with HEPA filter removed
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 85 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Sep 6, 2026, 2:20 AM EDT
Completed Not applicable Interventional

Indoor Air Quality and Respiratory Symptoms in Former Smokers

NCT02956213
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
HEPA portable air filter, Sham Control/Active Comparator
Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
40 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 12, 2019 · Synced Sep 6, 2026, 2:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Environmental Intervention to Reduce Allergens in Urban Schools and Childhood Asthma

NCT01913795
View directory record Official record
Conditions
Asthma
Interventions
integrated pest management, air purifier, Sham air purifier
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
4 Years to 15 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 6, 2022 · Synced Sep 6, 2026, 2:20 AM EDT
Recruiting Not applicable Interventional

Reducing AIR Pollution Exposure to Lower Blood PRESSURE Among New York City Public Housing Residents

NCT05874479
View directory record Official record
Conditions
Blood Pressure
Interventions
Active PAC, Sham PAC
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 100 Years
Enrollment
440 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Sep 6, 2026, 2:20 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Sunscreen Based on Bioadhesive Nanoparticles

NCT02668536
View directory record Official record
Conditions
Melanoma, UV Ray Skin Damage
Interventions
Standard Sunscreen, BNP
Drug · Device
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 12, 2018 · Synced Sep 6, 2026, 2:20 AM EDT
Recruiting Not applicable Interventional

The Airports, Air Quality, and Asthma (AAA) Study

NCT07047430
View directory record Official record
Conditions
Pediatric Asthma
Interventions
Portable air cleaner with HEPA filter, Less effective portable air cleaner (no HEPA)
Device
Lead sponsor
University of Washington
Other
Eligibility
6 Years to 12 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 1, 2025 · Synced Sep 6, 2026, 2:20 AM EDT
Completed Not applicable Interventional

Home Air Filtration for Traffic-Related Air Pollution

NCT04279249
View directory record Official record
Conditions
Cardiovascular Risk Factor, Blood Pressure
Interventions
HEPA Air Filtration, Sham HEPA Air Filtration
Other
Lead sponsor
UConn Health
Other
Eligibility
30 Years and older
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 31, 2024 · Synced Sep 6, 2026, 2:20 AM EDT
Active, not recruiting Not applicable Interventional

Breathing Device in Postural Orthostatic Tachycardia Syndrome (POTS)

NCT00962728
View directory record Official record
Conditions
Postural Tachycardia Syndrome, Postural Orthostatic Tachycardia Syndrome
Interventions
Inspiratory Threshold Device (Res-Q-Gard ITD), Sham Inspiratory Threshold Device
Device
Lead sponsor
Alfredo Gamboa
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 21, 2025 · Synced Sep 6, 2026, 2:20 AM EDT
Completed Not applicable Interventional Results available

Cleaner Air for Better Cardiac Biomarkers

NCT05379400
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
Portable air cleaner (PAC), Sham Portable air cleaner (PAC)
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 100 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Sep 6, 2026, 2:20 AM EDT
Active, not recruiting Not applicable Interventional

Far Red Light to Improve Functioning in PAD

NCT06165016
View directory record Official record
Conditions
Peripheral Artery Disease, Peripheral Vascular Disease, Aging, Walking, Difficulty
Interventions
Far red light therapy, Sham light therapy
Device
Lead sponsor
Northwestern University
Other
Eligibility
50 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Birmingham, Alabama • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 6, 2026, 2:20 AM EDT
Recruiting Not applicable Interventional

Action Towards Health Equity and Improved Air Quality in the Duwamish Valley: A Multilevel Asthma Intervention

NCT06552013
View directory record Official record
Conditions
Asthma in Children
Interventions
MERV 13 filter, Sham filter
Other
Lead sponsor
University of Washington
Other
Eligibility
6 Years to 17 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 12, 2024 · Synced Sep 6, 2026, 2:20 AM EDT
Not listed Phase 2Phase 3 Interventional

Safety and Effectiveness of the PXL Platinum 330 System With Riboflavin Solution for Refractory Corneal Ulcers

NCT05255016
View directory record Official record
Conditions
Keratitis, Corneal Ulcer
Interventions
PXL Platinum 330 system + Riboflavin 0.25% TE Solution, Sham CXL + Artificial Tears
Combination Product · Other
Lead sponsor
Peschke GmbH
Industry
Eligibility
18 Years and older
Enrollment
488 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
12
States / cities
Littleton, Colorado • Fort Myers, Florida • Tampa, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Oct 27, 2022 · Synced Sep 6, 2026, 2:20 AM EDT
Terminated Not applicable Interventional

Chronotherapy Randomized Controlled Trial

NCT02176824
View directory record Official record
Conditions
Major Depressive Disorder, Bipolar Depression, Suicidal Ideation
Interventions
Total Sleep deprivation, Sleep Phase Advance, and Bright Light Therapy, Partial Sleep deprivation, Sleep Phase Delay, and Low amber light., Treatment as usual
Behavioral · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 90 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 29, 2019 · Synced Sep 6, 2026, 2:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Boston Puerto Rican Health Study

NCT03187704
View directory record Official record
Conditions
Air Pollution, Cardiovascular Health
Interventions
HEPA air filtration
Other
Lead sponsor
Tufts University
Other
Eligibility
45 Years to 80 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 19, 2017 · Synced Sep 6, 2026, 2:20 AM EDT
Recruiting Not applicable Interventional

Asthma Intervention With Residential Ventilation and Air Cleaner (AIRVAC) Study

NCT07196436
View directory record Official record
Conditions
Asthma Control, Pulmonary Function, Quality of Life, Stress, Sleep Quality
Interventions
Energy Recovery Ventilator, Portable Air Cleaner, Energy Recovery Ventilator (Sham), Portable Air Cleaner (Sham)
Device
Lead sponsor
The University of Texas at Arlington
Other
Eligibility
5 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Arlington, Texas • Plano, Texas
Source: ClinicalTrials.gov public record
Updated Oct 28, 2025 · Synced Sep 6, 2026, 2:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Reducing Particulate Matter-associated Cardiovascular Health Effects for Seniors

NCT04103346
View directory record Official record
Conditions
Cardiometabolic Health
Interventions
air filtration with air purifier with hepa filter, sham
Other
Lead sponsor
University of Michigan
Other
Eligibility
60 Years and older
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Sep 6, 2026, 2:20 AM EDT
Recruiting Not applicable Interventional

Project 4: ACHIEVE PATHFINDER

NCT06070428
View directory record Official record
Conditions
Heart Failure
Interventions
PAC provision at hospital discharge, Control non-intervention; PAC without filter
Other
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Sep 6, 2026, 2:20 AM EDT
Completed Not applicable Interventional

Home Air Purification for Eosinophilic COPD

NCT04252235
View directory record Official record
Conditions
COPD, Eosinophilia
Interventions
Air purifier, Sham air purifier
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
40 Years and older
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Sep 6, 2026, 2:20 AM EDT
Completed Not applicable Interventional

Clinical Trial of Air Cleaners to Improve Indoor Air Quality and COPD Health

NCT02236858
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
HEPA Air Cleaner, Sham HEPA Air Cleaner
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
40 Years and older
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 13, 2021 · Synced Sep 6, 2026, 2:20 AM EDT