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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Sham protocol Clear all
Recruiting Phase 1Phase 2 Interventional

Deep Repetitive Transcranial Magnetic Stimulation (rTMS) of the Precuneus for Alzheimer Disease (AD)

NCT06597942
View directory record Official record
Conditions
Alzheimer&Amp;Amp;#39;s Disease, Alzheimer Disease, Dementia Alzheimer Type, Mild Alzheimer&Amp;Amp;#39;s Disease, Moderate Alzheimer&Amp;Amp;#39;s Disease, Alzheimer&Amp;#39;s Disease (AD), Alzheimer&Amp;#39;s Dementia
Interventions
TMS, Transcranial Magnetic Stimulation Sham
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
60 Years to 100 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Sep 4, 2026, 7:33 AM EDT
Not yet recruiting Not applicable Interventional

Can a Specific OMT Protocol Influence Patient Pain and Associated Analgesia Use for Primary Headache Disorders?

NCT06546462
View directory record Official record
Conditions
Headache Disorders, Headache, Analgesia, Opioid Use, Osteopathy
Interventions
Osteopathic Manipulative Treatment (OMT), Sham Light touch arm
Other
Lead sponsor
New York Institute of Technology
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Old Westbury, New York
Source: ClinicalTrials.gov public record
Updated Mar 16, 2025 · Synced Sep 4, 2026, 7:33 AM EDT
Completed Not applicable Interventional Results available

t-RNS After Hand Recovery in Chronic Stroke

NCT05489146
View directory record Official record
Conditions
Stroke
Interventions
transcranial random noise stimulation and functional electrical stimulation facilitated task practice
Device
Lead sponsor
Amit Sethi
Other
Eligibility
18 Years to 80 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 27, 2022 · Synced Sep 4, 2026, 7:33 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

TMS With Real-time E-field and EEG Source Imaging

NCT06645613
View directory record Official record
Conditions
Healthy Volunteers Only
Interventions
Transcranial Magnetic Stimulation Device
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 26, 2026 · Synced Sep 4, 2026, 7:33 AM EDT
Recruiting Not applicable Interventional

Osteopathic Manipulative Therapy Effects on Post-Acute Sequelae of COVID-19 (PASC) or Long COVID

NCT06883513
View directory record Official record
Conditions
Long-COVID, PASC, Long COVID Syndrome
Interventions
Osteopathic Manipulative Therapy Long-COVID protocol, Osteopathic Manipulative Therapy NOT Long-COVID treatment protocol
Other
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 18, 2025 · Synced Sep 4, 2026, 7:33 AM EDT
Completed Not applicable Interventional Results available

Acupuncture for Female IC/PBSyndrome and Its Effect on the Urinary Microbiome: A Randomized Controlled Trial

NCT02232282
View directory record Official record
Conditions
Painful Bladder Syndrome, Interstitial Cystitis
Interventions
standard acupuncture treatment, Control Sham/Minimal Acupuncture
Device
Lead sponsor
Loyola University
Other
Eligibility
21 Years to 65 Years · Female only
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 13, 2022 · Synced Sep 4, 2026, 7:33 AM EDT
Not yet recruiting Phase 3 Interventional

Effects, Metabolic Mechanisms and Predictors of Response to Acupuncture in Treating Psychoneurological Symptoms Among Breast Cancer Survivors

NCT07695948
View directory record Official record
Conditions
Breast Cancer
Interventions
Acupuncture, Sham acupuncture
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older · Female only
Enrollment
252 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 4, 2026, 7:33 AM EDT
Completed Not applicable Interventional Results available

Neuromodulation for Post-Traumatic Stress Disorder

NCT02377089
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Trigeminal Nerve Stimulation, Placebo
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years to 65 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 7, 2022 · Synced Sep 4, 2026, 7:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Aerobic Exercise with Blood Flow Restriction on Post-exercise Hypotension in Young Adults: the Role of Histamine Receptors

NCT06629337
View directory record Official record
Conditions
Prehypertension (elevated Blood Pressure) or Hypertension
Interventions
H1 receptor blockade: 540 mg (Allegra), H2 receptor blockade: 40 mg (Pepcid AC)
Genetic
Lead sponsor
California Baptist University
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Riverside, California
Source: ClinicalTrials.gov public record
Updated Oct 7, 2024 · Synced Sep 4, 2026, 7:33 AM EDT
Completed Phase 2 Interventional

HKT-500-US12 In Adult Patients With OA Knee Pain

NCT00647231
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
HKT-500 Topical Patch, Placebo Patch
Drug · Other
Lead sponsor
Hisamitsu Pharmaceutical Co., Inc.
Industry
Eligibility
45 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
29
States / cities
Birmingham, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 25 more
Source: ClinicalTrials.gov public record
Updated Jun 3, 2015 · Synced Sep 4, 2026, 7:33 AM EDT
Completed Not applicable Interventional

Ischemic Preconditioning Claudication Study

NCT03511157
View directory record Official record
Conditions
Intermittent Claudication, Ischemia Vascular, Peripheral Arterial Disease, Peripheral Vascular Disease
Interventions
Ischemic Preconditioning, Control Group
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 13, 2022 · Synced Sep 4, 2026, 7:33 AM EDT
Completed Not applicable Interventional Results available

The Effects Upon the Bladder of Transcutaneous Tibial Nerve Stimulation in Acute Traumatic Spinal Cord Injury

NCT02573402
View directory record Official record
Conditions
Spinal Cord Injury, Neurogenic Bladder
Interventions
Transcutaneous Tibial Nerve Stimulation, Control
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 9, 2018 · Synced Sep 4, 2026, 7:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of OMT on Functional Outcomes and Anti-inflammatory Biomarkers in Mild to Moderate Traumatic Brain Injury

NCT03163901
View directory record Official record
Conditions
Vestibular Disorder, Headache, Traumatic Brain Injury
Interventions
Osteopathic Manipulative Treatment
Other
Lead sponsor
Michigan State University
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Mason, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 23, 2020 · Synced Sep 4, 2026, 7:33 AM EDT
Completed Not applicable Interventional

Frontoparietal Synchronization to Modulate Drug Craving in Opioid Use Disorder

NCT03907644
View directory record Official record
Conditions
Opioid-use Disorder
Interventions
Transcranial Alternating Current Stimulation (tACS)
Device
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 61 Years · Male only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jul 10, 2023 · Synced Sep 4, 2026, 7:33 AM EDT
Withdrawn Not applicable Interventional

A Pilot Study of Deep Brain Stimulation of the Amygdala for Treatment-Refractory Combat Post-Traumatic Stress Disorder

NCT01658748
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Week 0 Medtronic 3387 electrodes/Activa PC amygdala DBS, Week 12 Medtronic 3387 electrodes/Activa PC amygdala DBS
Device
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
25 Years to 65 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 28, 2013 · Synced Sep 4, 2026, 7:33 AM EDT
Recruiting Not applicable Interventional

AuriculoTherapy NeuroImaging

NCT06825390
View directory record Official record
Conditions
Low Back Pain, Chronic Low-back Pain, Back Pain, Low, Lumbar Disc Disease, Lumbar Discogenic Pain, Lumbar Pain Syndrome, Lumbar Post-Laminectomy Syndrome, Back Pain Lower Back Chronic, Back Pain Without Radiation, Pain;Back Low;Chronic
Interventions
Cryo-auriculotherapy, Sham auriculotherapy, Experimental auricular stimulation
Device · Other
Lead sponsor
Keith M Vogt
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Sep 4, 2026, 7:33 AM EDT
Active, not recruiting Phase 1Phase 2 Interventional

Study of AR-14034 in Participants With Neovascular Age-Related Macular Degeneration (nAMD)

NCT05769153
View directory record Official record
Conditions
Neovascular Age-related Macular Degeneration (nAMD)
Interventions
AR-14034 SR implant lower dose, AR-14034 SR implant higher dose, AR-14034 SR implant, Aflibercept Injection, Sham procedure
Drug
Lead sponsor
Alcon Research
Industry
Eligibility
50 Years and older
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
42
States / cities
Dothan, Alabama • Gilbert, Arizona • Phoenix, Arizona + 37 more
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Sep 4, 2026, 7:33 AM EDT
Completed Not applicable Interventional

Acupuncture for Tonsillectomy Pain

NCT01389349
View directory record Official record
Conditions
Children, Postoperative Pain, Tonsillar Hypertrophy, Obstructive Sleep Apnea, Chronic Tonsillitis
Interventions
Acupuncture, Sham Control
Other
Lead sponsor
Children's ENT of San Diego, Inc.
Other
Eligibility
2 Years to 17 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
2
States / cities
El Centro, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated May 17, 2012 · Synced Sep 4, 2026, 7:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Noninvasive Modulation of Motivational Brain Regions in Healthy Volunteers

NCT04972786
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Repetitive Transcranial Magnetic Stimulation
Device
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years to 55 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jul 15, 2024 · Synced Sep 4, 2026, 7:33 AM EDT
Terminated Not applicable Interventional

OMT of Somatic Dysfunction and Chronic Low Back Pain in Patients With Type 2 Diabetes Mellitus

NCT02054650
View directory record Official record
Conditions
Chronic Low Back Pain, Type 2 Diabetes Mellitus
Interventions
Osteopathic Manual Treatment (OMT), Sham OMT
Other
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
18 Years to 79 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated May 25, 2016 · Synced Sep 4, 2026, 7:33 AM EDT
Completed Not applicable Interventional Results available

A Study Using Transorbital Alternating Current Stimulation for People With Glaucoma

NCT03188042
View directory record Official record
Conditions
Glaucoma
Interventions
rtACS Stimulation, Sham Intervention
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
50 Years to 70 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 8, 2024 · Synced Sep 4, 2026, 7:33 AM EDT
Terminated Not applicable Interventional

Condensed Percutaneous Tibial Nerve Stimulation (PTNS) Protocol

NCT03559946
View directory record Official record
Conditions
Overactive Bladder Syndrome
Interventions
percutaneous tibial nerve stimulation (PTNS), Sham procedure
Device
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Aug 13, 2023 · Synced Sep 4, 2026, 7:33 AM EDT
Recruiting Not applicable Interventional

Assessing the Impact of dTMS on Neural Targets Associated With Alcohol Use Disorder

NCT06949423
View directory record Official record
Conditions
Alcohol Use Disorder (AUD), Transcranial Magnetic Stimilation
Interventions
Deep Transcranial Magnetic Stimulation (dTMS) H7 coil - Active, Deep Transcranial Magnetic Stimulation (dTMS) H7 coil - Sham
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Sep 4, 2026, 7:33 AM EDT
Completed Not applicable Interventional Results available

Auricular Acupuncture For The Treatment Of Non-Epileptic Seizures

NCT01919307
View directory record Official record
Conditions
Convulsion, Non-Epileptic
Interventions
Auricular acupuncture
Other
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
18 Years to 75 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 4, 2018 · Synced Sep 4, 2026, 7:33 AM EDT