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Showing 1–14 of 14 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Sham tDCS and Mindfulness Clear all
Recruiting Not applicable Interventional

Transcranial Direct Current Stimulation for Depression

NCT07042217
View directory record Official record
Conditions
Unipolar Depression
Interventions
transcranial direct current stimulation (tDCS) and mindfulness instruction, Sham tDCS and Mindfulness
Device
Lead sponsor
Soterix Medical
Industry
Eligibility
22 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Woodbridge, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Sep 28, 2026, 7:29 AM EDT
Completed Not applicable Interventional Results available

Home-based tDCS and Mindfulness-based Meditation for Self-management of Clinical Pain and Symptoms

NCT04375072
View directory record Official record
Conditions
Osteo Arthritis Knee
Interventions
active tDCS paired with active MBM, sham tDCS paired with active MBM, active tDCS paired with sham MBM, sham tDCS paired with sham MBM
Device
Lead sponsor
University of Arizona
Other
Eligibility
50 Years to 85 Years
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 11, 2025 · Synced Sep 28, 2026, 7:29 AM EDT
Completed Not applicable Interventional Results available

Brain Stimulation and Meditation for Pain After Total Knee Arthroplasty

NCT05673720
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
active tDCS paired with active MBM, sham tDCS paired with sham MBM
Device
Lead sponsor
Florida State University
Other
Eligibility
50 Years to 85 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Nov 23, 2025 · Synced Sep 28, 2026, 7:29 AM EDT
Completed Not applicable Interventional Results available

Remotely Supervised tDCS for Persistent Post-traumatic Headache

NCT04012853
View directory record Official record
Conditions
Persistent Post Traumatic Headache, Mild Traumatic Brain Injury
Interventions
transcranial direct current stimulation
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
20 Years to 60 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 13, 2023 · Synced Sep 28, 2026, 7:29 AM EDT
Completed Not applicable Interventional Results available

Self Transcranial Direct Current Stimulation and Mindfulness-based Meditation for Pain in Older Adults With Knee Osteoarthritis

NCT03747640
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Self Transcranial Direct Current Stimulation (tDCS), mindfulness-based meditation, Sham Self Transcranial Direct Current Stimulation (tDCS), sham meditation
Device · Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
50 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2022 · Synced Sep 28, 2026, 7:29 AM EDT
Completed Not applicable Interventional Results available

Mindful Breathing and tDCS for Depression

NCT03897699
View directory record Official record
Conditions
Depression, Depressive Disorder
Interventions
Transcranial Direct Current Stimulation, Mindful Breathing, Sham
Device · Behavioral · Other
Lead sponsor
University of Minnesota
Other
Eligibility
16 Years to 24 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 12, 2023 · Synced Sep 28, 2026, 7:29 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Interactions Between Placebo Effects and Mindful Awareness State

NCT07108101
View directory record Official record
Conditions
Placebo Effect, Mindfulness, Pain, Transcranial Direct Current Stimulation (tDCS)
Interventions
tDCS stimulation (sham), tDCS stimulation (real), Mindful state induction, No minfulness induction
Behavioral
Lead sponsor
Trustees of Dartmouth College
Other
Eligibility
18 Years to 55 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Hanover, New Hampshire
Source: ClinicalTrials.gov public record
Updated Aug 5, 2025 · Synced Sep 28, 2026, 7:29 AM EDT
Completed Not applicable Interventional Results available

Pain Relief for OsteoArthritis Through Combined Treatment (PROACT)

NCT03884374
View directory record Official record
Conditions
Osteoarthritis of Knee
Interventions
Focused Breathing and Attention Training (BAT), Standard Breathing and Attention Training (BAT), Transcranial Direct Current Stimulation (tDCS), Sham Transcranial Direct Current Stimulation (tDCS)
Behavioral · Device
Lead sponsor
University of Florida
Other
Eligibility
45 Years to 85 Years
Enrollment
317 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
2
States / cities
Birmingham, Alabama • Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 14, 2025 · Synced Sep 28, 2026, 7:29 AM EDT
Completed Not applicable Interventional Results available

Brain Stimulation and Enhancing Cognition in Older Adults

NCT03653351
View directory record Official record
Conditions
Cognitive Impairment, Mild, Depressive Symptoms, Anxiety
Interventions
Active Transcranial Direct Current Stimulation (tDCS), Sham Transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
60 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
2
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 7, 2021 · Synced Sep 28, 2026, 7:29 AM EDT
Recruiting Phase 2 Interventional

Home-Based Transcranial Direct Current Stimulation (tDCS) for Depression in Multiple Sclerosis (MS)

NCT06901687
View directory record Official record
Conditions
Multiple Sclerosis, Depression
Interventions
Active tDCS, Sham tDCS
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Sep 28, 2026, 7:29 AM EDT
Completed Phase 2 Interventional Results available

A Teleheath tDCS Approach to Decrease Cannabis Use

NCT05005013
View directory record Official record
Conditions
Cannabis Use Disorder, Multiple Sclerosis
Interventions
Transcranial Direct Current Stimulation (tDCS), Sham - Transcranial Direct Current Stimulation (tDCS), Mindfulness
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years to 65 Years · Female only
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 23, 2025 · Synced Sep 28, 2026, 7:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Tobacco Smoking: a Transcranial Direct Current Stimulation (TDCS) Telehealth Study

NCT05460676
View directory record Official record
Conditions
Smoking Cessation
Interventions
Transcranial Direct Current Stimulation (tDCS), Mindfulness, Sham - Transcranial Direct Current Stimulation (tDCS)
Device · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years to 75 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 28, 2026, 7:29 AM EDT
Completed Not applicable Interventional Results available

Mindfulness-Based Intervention and Transcranial Direct Current Brain Stimulation to Reduce Heavy Drinking

NCT02861807
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Intoxication, Alcoholism
Interventions
Brain stimulation with mindfulness-based relapse prevention
Device
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Feb 4, 2020 · Synced Sep 28, 2026, 7:29 AM EDT
Recruiting Not applicable Interventional

RS-tDCS for Cannabis Use Disorder: The C.A.R.E.S. Initiative

NCT07184983
View directory record Official record
Conditions
Cannabis Use Disorder
Interventions
Active Transcranial Direct Current Stimulation (tDCS), Sham Transcranial Direct Current Stimulation (tDCS), Mindfulness meditation
Device · Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
22 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Sep 28, 2026, 7:29 AM EDT