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ClinicalTrials.gov public records Last synced Sep 19, 2026, 5:49 PM EDT

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Showing 1–24 of 529 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Sham transcranial direct current stimulation Clear all
Terminated Not applicable Interventional Results available

Transcranial Direct Current Stimulation to Lower Neuropathic Pain in People With Multiple Sclerosis

NCT03219073
View directory record Official record
Conditions
Multiple Sclerosis, Neuropathic Pain
Interventions
Active tDCS using tDCS device, SHAM tDCS using tDCS device
Device
Lead sponsor
Thorsten Rudroff
Other
Eligibility
18 Years to 65 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 28, 2022 · Synced Sep 19, 2026, 5:49 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of Brain-stimulation on Metamemory Monitoring and Control

NCT03693729
View directory record Official record
Conditions
Healthy
Interventions
HD-tDCS
Device
Lead sponsor
Brooklyn College of the City University of New York
Other
Eligibility
18 Years to 35 Years
Enrollment
216 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Jul 9, 2020 · Synced Sep 19, 2026, 5:49 PM EDT
Recruiting Not applicable Interventional

Remotely-supervised Neuromodulation in PPA

NCT07260253
View directory record Official record
Conditions
Primary Progressive Aphasia(PPA), Progressive Aphasia, Progressive Aphasia in Alzheimer's Disease, Logopenic Progressive Aphasia (LPA), Logopenic Variant Primary Progressive Aphasia, Logopenic Variant of Primary Progressive Aphasia (LPA)
Interventions
Lexical Retrieval Cascade Treatment, Remotely Supervised Transcranial Direct Current Stimulation- Active, Remotely Supervised Transcranial Direct Current Stimulation - Sham
Behavioral · Device
Lead sponsor
Maya Henry
Other
Eligibility
40 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
2
States / cities
San Francisco, California • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Sep 19, 2026, 5:49 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Psychobiological Responses Following Exercise and Brain Stimulation

NCT06874595
View directory record Official record
Conditions
Psychological
Interventions
Cycling exercise at 65% of HRR for 20 minutes followed by HD-tDCS (exercise + HD-tDCS), Cycling exercise at 65% of HRR exercise followed by sham HD-tDCS (exercise + sham tDCS), No exercise followed by HD-tDCS (no exercise + HD-tDCS)., State Anxiety Inventory, Visual Analog Scale for Anxiety
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 50 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Sep 19, 2026, 5:49 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Cerebral Excitability and Cognitive Performance

NCT03807934
View directory record Official record
Conditions
Cognitive Change
Interventions
Stimulation via Soterix Medical or Neuroelectrics noninvasive brain stimulation systems
Other
Lead sponsor
Tufts University
Other
Eligibility
18 Years to 65 Years
Enrollment
1,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 4, 2021 · Synced Sep 19, 2026, 5:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Metaplasticity Experimental Design and Comparison of Motor Outcome Measure Sensitivity to Change

NCT03304262
View directory record Official record
Conditions
Healthy
Interventions
rTMS
Device
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Aug 24, 2023 · Synced Sep 19, 2026, 5:49 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Investigating Accelerated Learning in Healthy Subjects

NCT03055884
View directory record Official record
Conditions
Healthy Adults
Interventions
tDCS, Verbal paired-associate learning task
Device · Behavioral
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
18 Years to 35 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Jan 25, 2022 · Synced Sep 19, 2026, 5:49 PM EDT
Recruiting Not applicable Interventional

Home-based TDCS (Transcranial Direct Current Stimulation) for Cognitive and Behavioral Symptoms in Huntington's Disease

NCT06843252
View directory record Official record
Conditions
Huntington Disease
Interventions
Transcranial direct current stimulation (tDCS), Sham tDCS
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 85 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Sep 19, 2026, 5:49 PM EDT
Completed Phase 2 Interventional

Brain Monitoring, tDCS and Robotic Training in SCI

NCT06813287
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Electroencephalography (EEG), Upper extremity robot
Diagnostic Test · Device
Lead sponsor
Kathleen Friel
Other
Eligibility
16 Years to 65 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Sep 19, 2026, 5:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Repeated Prefrontal Cortex Stimulation on Antisocial and Aggressive Behavior

NCT02674516
View directory record Official record
Conditions
Antisocial Behavior, Aggression
Interventions
Transcranial direct current stimulation, Sham transcranial direct current stimulation
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 17, 2022 · Synced Sep 19, 2026, 5:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Brain and Cognitive Changes After Reasoning Training in Individuals With Mild Cognitive Impairment

NCT02596906
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
tDCS, Sham tDCS
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
50 Years to 80 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 29, 2023 · Synced Sep 19, 2026, 5:49 PM EDT
Completed Not applicable Interventional

Treatment of Memory Disorders in Gulf War Illness With High Definition Transcranial Direct Cortical Stimulation

NCT03542383
View directory record Official record
Conditions
Memory Disorders, Word Finding Difficulty
Interventions
High Definition Transcranial Direct Current Stimulation, Sham High Definition Transcranial Direct Current Stimulation
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
45 Years to 78 Years
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Sep 19, 2026, 5:49 PM EDT
Completed Not applicable Interventional Results available

Using Transcranial Direct Current Stimulation (tDCS) to Improve Post-Stroke Aphasia

NCT01709383
View directory record Official record
Conditions
Aphasia
Interventions
Transcranial Direct Current Stimulation, Sham Stimulation
Device
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 5, 2017 · Synced Sep 19, 2026, 5:49 PM EDT
Completed Not applicable Interventional Results available

Improving Visual Attention in Schizophrenia

NCT03880227
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder
Interventions
Active anodal tDCS, Sham tDCS
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
18 Years to 60 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Jul 12, 2021 · Synced Sep 19, 2026, 5:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cognitive Enhancement Through Model-based and Individualized Neurostimulation

NCT06235970
View directory record Official record
Conditions
Transcranial Electrical Stimulation (tES)
Interventions
Transcranial electrical stimulation (tES) including SHAM
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 45 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Sep 19, 2026, 5:49 PM EDT
Completed Not applicable Interventional Results available

Cerebellar tDCS and Balance Training in PwMS

NCT04391023
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Sham Transcranial Direct Current Stimulation (tDCS), Balance Training, 2 mA Transcranial Direct Current Stimulation, 4 mA Transcranial Direct Current Stimulation
Device · Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 70 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 17, 2024 · Synced Sep 19, 2026, 5:49 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Transcranial Direct Current Stimulation on Pain Perception

NCT01860950
View directory record Official record
Conditions
Pain
Interventions
anodal tDCS, cathodal tDCS, sham tDCS
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 75 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 3, 2018 · Synced Sep 19, 2026, 5:49 PM EDT
Terminated Not applicable Interventional

Transcranial Treatments in Eating Disorders

NCT02535780
View directory record Official record
Conditions
Anorexia Nervosa, Bulimia Nervosa
Interventions
Transcranial magnetic stimulation, Transcranial direct current stimulation
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 24, 2016 · Synced Sep 19, 2026, 5:49 PM EDT
Active, not recruiting Not applicable Interventional

Transcranial Direct Current Stimulation for Cognitive Improvement in Parkinson's Patients

NCT03191916
View directory record Official record
Conditions
Parkinson Disease
Interventions
transcranial direct current stimulation, Sham (for transcranial direct current stimulation)
Device
Lead sponsor
Sanford Health
Other
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2025
U.S. locations
1
States / cities
Fargo, North Dakota
Source: ClinicalTrials.gov public record
Updated Mar 3, 2025 · Synced Sep 19, 2026, 5:49 PM EDT
Completed Not applicable Interventional Results available

Transcranial Direct Current Stimulation (tDCS) in Human Subjects With PTSD Receiving an Exposure-based, Behavioral Therapy

NCT05419999
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Soterix 1x1 tDCS mini CT, Sham Soterix 1x1 tDCS Mini CT, Written Exposure Therapy (WET)
Device · Other · Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced Sep 19, 2026, 5:49 PM EDT
Completed Not applicable Interventional Results available

Brain Stimulation and Hand Training in Children With Hemiparesis

NCT02250092
View directory record Official record
Conditions
Pediatric Hemiparesis
Interventions
Transcranial Direct Current Stimulation (tDCS), Placebo Comparator
Device
Lead sponsor
University of Minnesota
Other
Eligibility
8 Years to 21 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
2
States / cities
Minneapolis, Minnesota • Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 17, 2020 · Synced Sep 19, 2026, 5:49 PM EDT
Completed No phase listed Observational

Transcranial Direct Current Stimulation and Autism

NCT01603225
View directory record Official record
Conditions
Autism Spectrum Disorders
Interventions
Transcranial Direct Current Stimulation (tDCS)
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
14 Years to 79 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 23, 2023 · Synced Sep 19, 2026, 5:49 PM EDT
Completed Not applicable Interventional Results available

Brain Stimulation and Cognitive Training - Efficacy

NCT05111548
View directory record Official record
Conditions
Schizophrenia, Schizo Affective Disorder, Bipolar Disorder
Interventions
tDCS (Active), BrainHQ, tDCS (Inactive)
Device · Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Sep 19, 2026, 5:49 PM EDT
Not yet recruiting Not applicable Interventional

Applying Neuromodulation to Boost the Efficacy of Motivational Interviewing

NCT07787572
View directory record Official record
Conditions
Cannabis Use Disorder
Interventions
transcranial alternating current stimulation, sham transcranial alternating current stimulation, Motivational interviewing (MI)
Device · Behavioral
Lead sponsor
The Mind Research Network
Other
Eligibility
21 Years to 65 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Sep 19, 2026, 5:49 PM EDT