- Conditions
- Cognitive Aging, Alzheimer Disease, Protection Against
- Interventions
- Active NIR-PBM, Sham NIR-PBM
- Device
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 65 Years to 89 Years
- Enrollment
- 168 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2026
- U.S. locations
- 2
- States / cities
- Tucson, Arizona • Gainesville, Florida
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 31
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Traumatic Brain Injury, Closed Head Injury, Cognitive Dysfunction
- Interventions
- Real LED Intervention, Sham LED Intervention
- Device
- Lead sponsor
- Boston VA Research Institute, Inc.
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2023
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Depression, Major Depressive Disorder
- Interventions
- Transcranial Light Therapy, Sham Transcranial Light Therapy
- Device
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 49 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts • Orangeburg, New York
- Conditions
- Phobias, Claustrophobia, Social Phobia
- Interventions
- Extinction Training, Low-Level Laser Therapy, Sham Low-Level Laser Therapy
- Behavioral · Device
- Lead sponsor
- University of Texas at Austin
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 112 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2020
- U.S. locations
- 1
- States / cities
- Austin, Texas
- Conditions
- Traumatic Brain Injury
- Interventions
- Transcranial photobiomodulator (tPBM), Transcranial photobiomodulator (tPBM) in sham mode
- Device
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 55 Years to 85 Years
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Major Depressive Disorder
- Interventions
- Transcranial Photobiomodulator, Sham
- Device
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 55 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 3
- States / cities
- Charlestown, Massachusetts • New York, New York • Orangeburg, New York
- Conditions
- Epilepsy
- Interventions
- Photobiomodulation
- Other
- Lead sponsor
- Cynthia Kerson
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 4
- States / cities
- North Miami, Florida • Cincinnati, Ohio • Warren, Ohio + 1 more
- Conditions
- Opioid-use Disorder, Depression, Anxiety, Craving
- Interventions
- unilateral transcranial photobiomodulation, near infrared mode, Sham treatment
- Device
- Lead sponsor
- MindLight, LLC
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 22 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019
- U.S. locations
- 1
- States / cities
- Newton Highlands, Massachusetts
- Conditions
- Opioid Use Disorder
- Interventions
- Sham unilateral transcranial photobiomodulation, transcranial photobiomodulation at 810 nm at 250 mW/cm2 for 4 minutes
- Other · Device
- Lead sponsor
- MindLight, LLC
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 130 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Newton Highlands, Massachusetts
- Conditions
- Major Depressive Disorder
- Interventions
- Transcranial Photobiomodulator, Sham
- Device
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 3
- States / cities
- Boston, Massachusetts • New York, New York • Orangeburg, New York
- Conditions
- Alzheimer Disease
- Interventions
- Vielight Neuro Gamma, Sham Vielight Neuro Gamma
- Device · Other
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 23 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2021
- U.S. locations
- 2
- States / cities
- San Francisco, California
- Conditions
- Cognitive Decline, Cognitive Dysfunction, Alzheimer Disease, Vascular Disease, Peripheral
- Interventions
- Transcranial Photobiomodulation, Transcranial Photobiomodulation helmet (Neuradiant 1070 Plus) with no light administered
- Device
- Lead sponsor
- The University of Texas at Arlington
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Arlington, Texas
- Conditions
- Parkinson Disease
- Interventions
- Active NIR-PBM (MedX 1116, MCT502), Sham NIR-PBM (MedX 1116, MCT502)
- Device
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 62 Years to 89 Years
- Enrollment
- 23 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Disease Type and/or Category Not Applicable
- Interventions
- Omnilux
- Device
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 80 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Symptoms of Anxiety
- Interventions
- Attention bias assessment and modification, Transcranial photobiomodulation
- Behavioral · Device
- Lead sponsor
- Francisco Gonzalez-Lima, PhD
- Other
- Eligibility
- 18 Years to 100 Years
- Enrollment
- 280 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Austin, Texas
- Conditions
- Cognition Improvement, Emotion Regulation
- Interventions
- Active transcranial photobiomodulation, Active MCT dietary supplementation, Sham photobiomodulation, Sham dietary supplementation
- Device · Dietary Supplement
- Lead sponsor
- Francisco Gonzalez-Lima, PhD
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 180 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2030
- U.S. locations
- 1
- States / cities
- Austin, Texas
- Conditions
- Mild Cognitive Impairment, Alzheimer Disease
- Interventions
- Active tPBM-2.0, Sham tPBM-2.0, 18F-MK-6240
- Device · Drug
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 65 Years to 85 Years
- Enrollment
- 196 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 3
- States / cities
- Boston, Massachusetts • New York, New York • Orangeburg, New York
- Conditions
- Mild Cognitive Impairment (MCI), Amyloid Pathology
- Interventions
- Active Vielight Neuro RX-Duo device -Active transcranial photobiomodulation, Sham Vielight Neuro RX-Duo device -Sham transcranial photobiomodulation
- Device
- Lead sponsor
- University of Oklahoma
- Other
- Eligibility
- 55 Years to 95 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Oklahoma City, Oklahoma
- Conditions
- Aging
- Interventions
- MedX 1116 Rehab Console, Sham MedX 1116 Rehab Console
- Device
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 62 Years to 99 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2023
- U.S. locations
- 2
- States / cities
- Gainesville, Florida
- Conditions
- Attention Deficit Hyperactivity Disorder, Attention Difficulties, Attention Deficit, Cognitive Deficit, Wellness
- Interventions
- Transcranial photobiomodulation, Sham transcranial photobiomodulation
- Device
- Lead sponsor
- Francisco Gonzalez-Lima, PhD
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 500 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2027
- U.S. locations
- 1
- States / cities
- Austin, Texas
- Conditions
- Aging
- Interventions
- Medx Console System, Sham Medx Console System, Vielight 810 intranasal stand alone unit, Sham Vielight 810 intranasal stand alone unit
- Device
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 65 Years to 89 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2026
- U.S. locations
- 2
- States / cities
- Tucson, Arizona • Gainesville, Florida
- Conditions
- Opioid-use Disorder, Opioid Dependence, Opioid Abuse
- Interventions
- supra-luminous LED, Sham
- Device
- Lead sponsor
- MindLight, LLC
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 39 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 2
- States / cities
- Belmont, Massachusetts • Newton Highlands, Massachusetts
- Conditions
- Alzheimer's Disease
- Interventions
- Photobiomodulation
- Device
- Lead sponsor
- Cedars-Sinai Medical Center
- Other
- Eligibility
- 55 Years to 89 Years
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Autism Spectrum Disorder
- Interventions
- Cognilum TM: Light Treatment Condition
- Device
- Lead sponsor
- State University of New York - Upstate Medical University
- Other
- Eligibility
- 2 Years to 8 Years
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 2
- States / cities
- New York, New York • Syracuse, New York