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ClinicalTrials.gov public records Last synced Oct 23, 2026, 4:19 AM EDT

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Showing 193–216 of 1,656 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Sham-Control Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Expressive Writing in Improving the Wellbeing or Comforting Capacity of Caregivers of Patients With Cancer

NCT02339870
View directory record Official record
Conditions
Caregiver
Interventions
Psychosocial Support for Caregiver, Questionnaire Administration, Sham Intervention
Other
Lead sponsor
University of Washington
Other
Eligibility
19 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 15, 2016 · Synced Oct 23, 2026, 4:19 AM EDT
Not yet recruiting Phase 1 Interventional

Nanopulse Laser Therapy

NCT07520383
View directory record Official record
Conditions
TBI (Traumatic Brain Injury)
Interventions
Nano-Pulsed Laser Therapy (NPLT)
Device
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 23, 2026, 4:19 AM EDT
Completed Phase 3 Interventional Results available

Efficacy and Safety of Intrathecal OAV101 (AVXS-101) in Pediatric Patients With Type 2 Spinal Muscular Atrophy (SMA)

NCT05089656
View directory record Official record
Conditions
Type 2 Spinal Muscular Atrophy
Interventions
OAV101, Sham control
Genetic · Procedure
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
2 Years to 17 Years
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
6
States / cities
Farmington, Connecticut • Chicago, Illinois • Strasburg, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Oct 23, 2026, 4:19 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Temporal Interference Methods for Non-invasive Deep Brain Stimulation, Study 1.3

NCT07594795
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Temporal Interference (TI) Electrical Stimulation - dACC 20 Hz TI Active, Temporal Interference (TI) Electrical Stimulation - dACC 20 Hz TI Sham, Temporal Interference (TI) Electrical Stimulation - dACC Comparison Frequency TI Active, Temporal Interference (TI) Electrical Stimulation - dACC Comparison Frequency TI Sham
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 23, 2026, 4:19 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

24 Week Clinical Trial to Evaluate Safety and Effectiveness of a Hair Growth System to Treat Male and Female Baldness

NCT01686295
View directory record Official record
Conditions
Androgenetic Alopecia
Interventions
iRestore Hair Rejuvenation System, sham device
Device
Lead sponsor
Freedom Laser Therapy, Inc.
Industry
Eligibility
25 Years to 60 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Paramus, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 18, 2012 · Synced Oct 23, 2026, 4:19 AM EDT
Recruiting Not applicable Interventional

Transcutaneous Auricular Neurostimulation After Lumbar Surgery

NCT06100172
View directory record Official record
Conditions
Pain, Postoperative, Opioid Use, Lumbar Spine Injury
Interventions
Sparrow Ascent Transcutaneous Auricular Neurostimulation (tAN), Sham Control Device
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Oct 23, 2026, 4:19 AM EDT
Recruiting Not applicable Interventional

Acupressure for the Reduction of Anxiety in Patients Receiving Cancer-Directed Therapy

NCT06723041
View directory record Official record
Conditions
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Interventions
Acupressure Therapy, Acupressure Therapy - placebo, Acupressure Therapy - self-administered, Health Promotion and Education, Survey Administration
Procedure · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 23, 2026, 4:19 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

tVNS During Motor Training in Older Adults

NCT06323954
View directory record Official record
Conditions
Older Adults
Interventions
tVNS stimulation, Sham stimulation
Procedure
Lead sponsor
Georgia Institute of Technology
Other
Eligibility
65 Years to 84 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 23, 2026, 4:19 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Using EEG Operant Conditioning to Improve Trait Self-Control and Promote Healthy Behavior

NCT01801254
View directory record Official record
Conditions
Obesity, Type II Diabetes, Cardiovascular Disease, Health Behavior
Interventions
STRIDES, Sham Control
Other
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 30, 2015 · Synced Oct 23, 2026, 4:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

4 mA tDCS, Estrogen, and Leg Muscle Fatigability

NCT04471805
View directory record Official record
Conditions
Healthy
Interventions
Sham transcranial direct current stimulation 4 mA, Transcranial direct current stimulation 4 mA
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 10, 2023 · Synced Oct 23, 2026, 4:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Semi-Recumbent Vibration Therapy in Older Adults

NCT02533063
View directory record Official record
Conditions
Sarcopenia, Aging
Interventions
VibeTech One
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
70 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 2, 2019 · Synced Oct 23, 2026, 4:19 AM EDT
Recruiting Not applicable Interventional

Auricular Acupressure in Prehabilitation

NCT06516198
View directory record Official record
Conditions
Frailty, Thoracic, Prehabilitation, Lung Surgery, Wedge Resection, Segmentectomy, Lobectomy, Pneumonectomy; Status
Interventions
Auricular Acupressure
Other
Lead sponsor
University of Chicago
Other
Eligibility
50 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 9, 2025 · Synced Oct 23, 2026, 4:19 AM EDT
Terminated Not applicable Interventional Results available

Low-level Laser Therapy in Patients With Chronic Fibromyalgia

NCT02948634
View directory record Official record
Conditions
Chronic Pain
Interventions
Sham Phoenix Laser Treatment, Active Phoenix Laser Treatment
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 3, 2020 · Synced Oct 23, 2026, 4:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Intra-articular Pulsed Radiofrequency Neuromodulation Versus Intra-articular Steroids for Painful Knee Osteoarthritis

NCT04238598
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Pulse Radiofrequency, Standard of Care Intra- Articular Injection, Placebo Intra-Articular Injection
Procedure
Lead sponsor
Center For Interventional Pain and Spine
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Exton, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 30, 2023 · Synced Oct 23, 2026, 4:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Latera RCT - Latera vs. Sham Control for Lateral Nasal Valve Collapse

NCT03400787
View directory record Official record
Conditions
Nasal Valve Collapse, Nasal Breathing
Interventions
Latera Implant, Sham Procedure
Device
Lead sponsor
Spirox, Inc.
Industry
Eligibility
18 Years and older
Enrollment
137 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
11
States / cities
Roseville, California • Torrance, California • Atlanta, Georgia + 8 more
Source: ClinicalTrials.gov public record
Updated Feb 9, 2021 · Synced Oct 23, 2026, 4:19 AM EDT
Completed Not applicable Interventional Results available

Efficacy, Safety and Economic Benefits of Topical Wound Oxygen Therapy in the Treatment of Chronic Diabetic Foot Ulcers

NCT02326337
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
TWO2 Device, Placebo Device
Device
Lead sponsor
AOTI Ltd.
Industry
Eligibility
18 Years to 89 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
10
States / cities
Phoenix, Arizona • Vacaville, California • Washington D.C., District of Columbia + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Oct 23, 2026, 4:19 AM EDT
Active, not recruiting Not applicable Interventional

rTMS Plus CCFES-mediated Functional Task Practice for Severe Stroke

NCT03870672
View directory record Official record
Conditions
Stroke, Hemiplegia, Cerebrovascular Accident (CVA), Hemiparesis
Interventions
Contralaterally Controlled Functional Electrical Stimulation, New rTMS approach, Conventional rTMS approach, Sham rTMS approach
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Oct 23, 2026, 4:19 AM EDT
Recruiting Not applicable Interventional

Shaping Habitual Impulses For a Tobacco-free Style

NCT07025772
View directory record Official record
Conditions
ST+ABR, ST+SHAM, ST-only
Interventions
ST+ABR, ST+Sham, ST Only
Behavioral
Lead sponsor
University of Houston
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 23, 2026, 4:19 AM EDT
Completed Not applicable Interventional

Acupressure in Hospitalized Patients

NCT02762435
View directory record Official record
Conditions
Acupressure
Interventions
sham, control, acupressure
Other
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Apr 25, 2017 · Synced Oct 23, 2026, 4:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Healing Touch on Sleep

NCT01870076
View directory record Official record
Conditions
Elective Reconstructive Surgery Population
Interventions
Healing Touch, Healing Touch, Sham, Control, Presence
Behavioral
Lead sponsor
Shriners Hospitals for Children
Other
Eligibility
5 Years to 25 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 20, 2017 · Synced Oct 23, 2026, 4:19 AM EDT
Withdrawn Phase 2Phase 3 Interventional Accepts healthy volunteers

Transcranial Magnetic Stimulation (TMS) Effects on Pain Perception

NCT00349050
View directory record Official record
Conditions
Pain, Trigeminal Neuralgia, Neuropathic Pain
Interventions
laboratory pain assessment, transcranial magnetic stimulation
Device · Procedure
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 60 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 30, 2012 · Synced Oct 23, 2026, 4:19 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Plantar Fasciitis Randomized Clinical Control Trial

NCT03231150
View directory record Official record
Conditions
Plantar Fascitis
Interventions
Local Steroid Injection into the plantar heel, Ultrasound Guided Injection, Anatomical Guided injection
Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 10, 2025 · Synced Oct 23, 2026, 4:19 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

The Effect of Strain-counterstrain on Ankle Instability

NCT02025569
View directory record Official record
Conditions
Other Instability, Ankle and Foot
Interventions
Strain Counterstrain, Sham strain counterstrain
Other
Lead sponsor
Long Island University
Other
Eligibility
18 Years to 55 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Jan 1, 2014 · Synced Oct 23, 2026, 4:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Manipulation of the Cervical Spine on Pain Biomarkers

NCT03176654
View directory record Official record
Conditions
Neck Pain, Posterior
Interventions
HVLAT manipulation, Sham HVLAT manipulation
Procedure
Lead sponsor
Loma Linda University
Other
Eligibility
20 Years to 45 Years · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Aug 1, 2019 · Synced Oct 23, 2026, 4:19 AM EDT