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Showing 1–23 of 23 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Sham-NMES Clear all
Completed Not applicable Interventional Results available

Use of Neuromuscular Electrostimulation (NMES) for Treatment or Prevention of ICU-Associated Weakness

NCT00709124
View directory record Official record
Conditions
Intensive Care Unit, Muscle Weakness
Interventions
Neuromuscular Electrostimulation (NMES) CareStim Muscle Stimulation Device (Care Rehab; McLean, VA), Sham
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 22, 2018 · Synced Sep 9, 2026, 3:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of NMES Therapy for Pain Relief Associated With Knee Osteoarthritis

NCT04367597
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Home-based Neuromuscular Electrical Stimulation (NMES) therapy
Device
Lead sponsor
CyMedica Orthopedics, Inc
Industry
Eligibility
21 Years and older
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
5
States / cities
Tucson, Arizona • Houston, Texas • Katy, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 17, 2021 · Synced Sep 9, 2026, 3:40 AM EDT
Terminated No phase listed Interventional Results available

Breath Synchronized Abdominal Muscle Stimulation to Facilitate Ventilator Weaning: a Pilot Study

NCT03019107
View directory record Official record
Conditions
Electric Stimulation, Respiration, Artificial, Ventilator Weaning
Interventions
Breath synchronized abdominal NMES, Sham breath synchronized abdominal NMES
Device
Lead sponsor
Liberate Medical
Industry
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Nov 7, 2021 · Synced Sep 9, 2026, 3:40 AM EDT
Completed Not applicable Interventional Results available

Efficacy of Electrical Stimulation for Dysphagia in Head & Neck Cancer Patients

NCT00629265
View directory record Official record
Conditions
Dysphagia
Interventions
Neurotech NT2000 Neuromuscular Electrical Stimulation (NMES)
Device
Lead sponsor
Boston Medical Center
Other
Eligibility
21 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
14
States / cities
Scottsdale, Arizona • San Diego, California • Evanston, Illinois + 8 more
Source: ClinicalTrials.gov public record
Updated Oct 30, 2014 · Synced Sep 9, 2026, 3:40 AM EDT
Terminated Not applicable Interventional

Quantifying Effects of Treatment of Pediatric Dysphonia

NCT00237679
View directory record Official record
Conditions
Voice Disorders, Gastroesophageal Reflux
Interventions
Neuromuscular Electrical Stimulation, Unstimulated
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
6 Years to 11 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 13, 2015 · Synced Sep 9, 2026, 3:40 AM EDT
Terminated Not applicable Interventional

Treatment of Muscle Weakness in Critically Ill Patients

NCT02247895
View directory record Official record
Conditions
Critical Illness, Respiratory Failure, Myopathy, Weakness
Interventions
Sham Treatment, Electrical stimulation
Device
Lead sponsor
Gerald Supinski
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 21, 2020 · Synced Sep 9, 2026, 3:40 AM EDT
Terminated Not applicable Interventional

Neuromuscular Electrical Stimulation (NMES) for Dysphagia in Neonates

NCT02007759
View directory record Official record
Conditions
Dysphagia
Interventions
VitalStim, Sham VitalStim
Device
Lead sponsor
Sanford Health
Other
Eligibility
36 Weeks to 42 Weeks
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Jul 17, 2017 · Synced Sep 9, 2026, 3:40 AM EDT
Completed Not applicable Interventional Results available

Controlled Study of Kneehab XP for Patients Undergoing Total Knee Replacement

NCT01548040
View directory record Official record
Conditions
Total Knee Replacement
Interventions
Kneehab XP, Quadriceps TENS
Device
Lead sponsor
Theragen Inc.
Industry
Eligibility
40 Years and older
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 10, 2018 · Synced Sep 9, 2026, 3:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Trigger Point Dry Needling With and Without Electrical Stimulation in Healthy Subjects

NCT07384247
View directory record Official record
Conditions
People With Identified Painful Trigger Points (Tp) Within the Soleus and Gastrocnemius Muscles Complex, Healthy Subjects or Volunteers
Interventions
Dry needling with electrical stimulation, Dry needling, Electrical stimulation, Sham
Procedure
Lead sponsor
University of Rhode Island
Other
Eligibility
18 Years to 55 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Kingston, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Sep 9, 2026, 3:40 AM EDT
Completed Not applicable Interventional

Pivotal Evaluation of Abdominal Neuromuscular Electrical Stimulation (VentFree) for Weaning From Mechanical Ventilation

NCT05759013
View directory record Official record
Conditions
Respiration, Artificial, Ventilators, Mechanical
Interventions
Breath synchronized abdominal FES, Sham breath synchronized abdominal FES
Device
Lead sponsor
Liberate Medical
Industry
Eligibility
22 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
15
States / cities
Long Beach, California • Jacksonville, Florida • Hines, Illinois + 9 more
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Sep 9, 2026, 3:40 AM EDT
Completed Not applicable Interventional Results available

NMES Efficacy on Patients With NBPP

NCT01999465
View directory record Official record
Conditions
Neonatal Brachial Plexus Palsy
Interventions
Standard NMES device, Sham NMES device
Device
Lead sponsor
University of Michigan
Other
Eligibility
3 Months to 9 Months
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 13, 2018 · Synced Sep 9, 2026, 3:40 AM EDT
Recruiting Not applicable Interventional

Transspinal Stimulation With and Without Blood Flow Restricted Exercise Via Telehealth in Persons With Tetraplegia

NCT05423600
View directory record Official record
Conditions
Tetraplegia/Tetraparesis
Interventions
BES + TS, Experimental: BES+sham TS
Procedure
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 70 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
3
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 9, 2026, 3:40 AM EDT
Not listed Not applicable Interventional

Electrical Stimulation After Botulinum Toxin Injections to the Upper Extremity

NCT04217187
View directory record Official record
Conditions
Stroke
Interventions
Neuromuscular Electrical Stimulation, Sham Electrical Stimulation
Device
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 6, 2020 · Synced Sep 9, 2026, 3:40 AM EDT
Completed Not applicable Interventional

Metabolic Health in Individuals With Spinal Cord Injury (SCI)

NCT03204240
View directory record Official record
Conditions
Spinal Cord Injuries, Skeletal Muscle Atrophy, Metabolic Disease
Interventions
Neuromuscular electrical stimulation
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 26, 2023 · Synced Sep 9, 2026, 3:40 AM EDT
Not listed Not applicable Interventional

Facilitating Functional Independence in Patients Receiving Prolonged Mechanical Ventilation

NCT02847988
View directory record Official record
Conditions
Muscle Weakness
Interventions
Neuromuscular electrical Stimulation (NMES), Sham Stimulation
Device
Lead sponsor
RML Specialty Hospital
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Hinsdale, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 10, 2021 · Synced Sep 9, 2026, 3:40 AM EDT
Completed Not applicable Interventional

BCI-controlled NMES in Subacute Stroke

NCT03379532
View directory record Official record
Conditions
Stroke
Interventions
BCI-NMES, Sham-NMES
Device
Lead sponsor
University Hospital, Geneva
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated May 7, 2024 · Synced Sep 9, 2026, 3:40 AM EDT
Terminated Not applicable Interventional

NMES to Improve Eyelid Functions in Cranial Nerve (CN) III and VII Palsy

NCT03239418
View directory record Official record
Conditions
Blepharoptosis, Lagophthalmos
Interventions
Neuromuscular electrical stimulation, Sham neuromuscular electrical stimulation
Device
Lead sponsor
Brooks Rehabilitation
Other
Eligibility
19 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 20, 2022 · Synced Sep 9, 2026, 3:40 AM EDT
Completed Not applicable Interventional

Electrical Stimulation to Strengthen Muscles in the Lower Legs in Patients Requiring Prolonged Mechanical Ventilation

NCT01825135
View directory record Official record
Conditions
Muscle Weakness
Interventions
Neuromuscular electrical stimulation, sham stimulation
Device
Lead sponsor
RML Specialty Hospital
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Hinsdale, Illinois
Source: ClinicalTrials.gov public record
Updated May 2, 2017 · Synced Sep 9, 2026, 3:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of a Home-based NMES Therapy for Knee Osteoarthritis Pain

NCT04128618
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
CyMedica e-vive NMES
Device
Lead sponsor
CyMedica Orthopedics, Inc
Industry
Eligibility
21 Years to 85 Years
Enrollment
159 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
2
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 24, 2020 · Synced Sep 9, 2026, 3:40 AM EDT
Completed Phase 2Phase 3 Interventional

Adjunctive Neuromuscular Electrical Stimulation for the Rehabilitation of Swallowing

NCT01279824
View directory record Official record
Conditions
Dysphagia
Interventions
swallowing therapy
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 90 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Chattanooga, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 4, 2012 · Synced Sep 9, 2026, 3:40 AM EDT
Completed Phase 2 Interventional Results available

Post Stroke Hand Functions: Bilateral Movements and Electrical Stimulation Treatments

NCT00369668
View directory record Official record
Conditions
Cerebrovascular Accident, Hemiplegia
Interventions
Bilateral movements and neuromuscular electrical stimulation, Bilateral movements and sham electrical stimulation
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
44 Years to 86 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 14, 2012 · Synced Sep 9, 2026, 3:40 AM EDT
Completed Not applicable Interventional

Muscle Stimulation for Physical Function During Stem Cell Transplant

NCT04364256
View directory record Official record
Conditions
Autologous Hematopoietic Stem Cell Transplant
Interventions
RS-4i Plus Sequential Stimulator (RS Medical, Vancouver, WA)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 1, 2026 · Synced Sep 9, 2026, 3:40 AM EDT
Terminated Not applicable Interventional Results available

Building Strength Through Rehabilitation for Heart Failure Patients (BISTRO-STUDY)

NCT03615469
View directory record Official record
Conditions
Heart Failure
Interventions
Transcutaneous electrical stimulation, Neuromuscular electrical stimulation
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 30, 2023 · Synced Sep 9, 2026, 3:40 AM EDT